Son Q Duong, Calista Dominy, Naveen Arivazhagan, David M Barris, Kali Hopkins, Kenan W D Stern, Nadine Choueiter, David Ezon, Jennifer Cohen, Mark K Friedberg, Ali N Zaidi, Girish N Nadkarni
{"title":"Machine learning prediction of right ventricular volume and ejection fraction from two-dimensional echocardiography in patients with pulmonary regurgitation.","authors":"Son Q Duong, Calista Dominy, Naveen Arivazhagan, David M Barris, Kali Hopkins, Kenan W D Stern, Nadine Choueiter, David Ezon, Jennifer Cohen, Mark K Friedberg, Ali N Zaidi, Girish N Nadkarni","doi":"10.1007/s10554-025-03368-z","DOIUrl":"10.1007/s10554-025-03368-z","url":null,"abstract":"<p><p>Right ventricular (RV) end-diastolic volume (RVEDV) and ejection fraction (RVEF) by cardiac MRI (cMRI) guide management in chronic pulmonary regurgitation (PR). Two-dimensional echocardiography suboptimally correlate with RV volumes. This study tested whether combination of guideline-directed RV measures in a machine learning (ML) framework improves quantitative assessment of RVEDV and RVEF. RV measurements were obtained on subjects with > mild PR who had cMRI and echocardiogram within 90 days. A gradient-boosted trees algorithm predicted cMRI RV dilation (RVEDV > 160 ml/m<sup>2</sup>) and RV dysfunction (RVEF<47%), first with \"guideline-only\" measures, and then with \"expanded-features\" to include 44 total echocardiographic, clinical, and demographic variables. Model performance was compared to clinician visual assessment. Of 232 studies (56% tetralogy of Fallot, 20% pulmonary stenosis), the median age was 21.5 years, 21 (9%) had RV dilation, and 42 (18%) had RV dysfunction. For RV dilation prediction, the guideline-only model area under the receiver operating characteristic (AUROC)=0.68, and expanded-features model AUROC=0.85. At 90% sensitivity, the expanded-features model had 73% specificity, 25% positive predictive value (PPV), and 99% negative predictive value (NPV) This was similar to clinician performance (sensitivity 81%, specificity 81%, PPV 29%, NPV 98%). For prediction of RV dysfunction, the guideline-only AUROC= 0.71, additional features did not improve the model, and clinicians outperformed the model. In patients with PR, a ML model combining guidelines for RV assessment with demographic and additional echocardiographic parameters may effectively rule-out those with significant RV dilation at clinical thresholds for intervention, and performs similarly to expert clinicians.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"899-912"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michal Schäfer, Jason P Glotzbach, Vikas Sharma, Anwar Tandar, Frederick G Welt, Matthew L Goodwin, Douglas Smego, Craig H Selzman, Sara J Pereira
{"title":"Aortic shape and diameter variations are predictive of short-term complications in transcatheter aortic valve replacement.","authors":"Michal Schäfer, Jason P Glotzbach, Vikas Sharma, Anwar Tandar, Frederick G Welt, Matthew L Goodwin, Douglas Smego, Craig H Selzman, Sara J Pereira","doi":"10.1007/s10554-025-03381-2","DOIUrl":"10.1007/s10554-025-03381-2","url":null,"abstract":"<p><strong>Introduction: </strong>Anatomic and geometric considerations are critical components for transcatheter aortic valve replacement (TAVR) procedural planning. Aortic root geometry and 3-dimensional orientation have been previously associated with short-term complications but with mixed and inconsistent results. The purpose of this study was to investigate aortic 3-dimensional anatomical shape variants identified by principal component analysis (PCA) and whether these variants are associated with short-term complications.</p><p><strong>Methods: </strong>Pre-TAVR planning chest CT angiograms (N = 100) were analyzed to create 3-dimensional anatomic aortic models were subjected to PCA. Aortic shape variants described by principal components (PCs) and their respective scores were calculated for each patient in addition to standard planning geometric parameters. A short-term composite complication outcome within 1-month from the implantation included major and minor stroke, life-threatening and major bleeding, stage 3 acute kidney injury, new heart block and moderate plus paravalvular leak (PVL).</p><p><strong>Results: </strong>A total of 25 patients (25%) experienced perioperative complications following TAVR. Shape based PCs were: PC1 - variation in aortic arch height, isthmic angle, and aortic arch angle; PC2 aortic length; PC3- aortic tilt. Diameter based PCs described: PC1- diameter size along the entire aortic length; PC2- aortic diameter tapering, PC3- ascending to arch diameter ratio. On univariable logistic regression, four variables were predictive of periprocedural complications, including the ascending aortic diameter at the level of Valsalva sinuses (OR: 0.88 (95%CI: 0.78-1.00), P = 0.044), PC1-shape scores (OR: 1.01 (95%CI: 1.00-1.02), P = 0.011), PC2-shape scores (OR: 0.98 (95%CI: 0.97-1.00), P = 0.034), and PC-1 diameter scores (OR: 0.98 (95%CI: 0.96-1.00), P = 0.023). An optimized multivariable model considering only PC1-shape and PC1-diameter revealed a C-statistic of 0.76 with a sensitivity of 92.0% and specificity of 32.0%.</p><p><strong>Conclusion: </strong>Aortic shape variants combining increased aortic arch height, acute isthmic angle, and mild aortic arch angle as identified by PCA were associated along with aortic size with higher rates of periprocedural complications in patients undergoing transfemoral TAVR. PCA identified shape variations outperformed standard 2-dimensional geometric measurements and could be considered as part of risk stratification prior to TAVR planning.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"955-965"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Dayer, Nicola Ciocca, Panagiotis Antiochos, Henri Lu, Denise Auberson, David Meier, Pierre Monney, Christoph Gräni, David Rotzinger, Jonathon Leipsic, Georgios Tzimas
{"title":"Comparison of cardiac computed tomography recommendations in recent ESC vs. ACC/AHA guidelines.","authors":"Nicolas Dayer, Nicola Ciocca, Panagiotis Antiochos, Henri Lu, Denise Auberson, David Meier, Pierre Monney, Christoph Gräni, David Rotzinger, Jonathon Leipsic, Georgios Tzimas","doi":"10.1007/s10554-025-03375-0","DOIUrl":"10.1007/s10554-025-03375-0","url":null,"abstract":"<p><p>Cardiac computed tomography (CCT) continues to expand with increasing applications and technological advancements. Growing evidence on the clinical utility of CCT necessitates evaluating how this knowledge is incorporated into European Society of Cardiology (ESC) and American College of Cardiology (ACC)/American Heart Association (AHA) guidelines. We aimed to provide a comprehensive comparison of CCT indications between ESC and ACC/AHA guidelines to identify areas of consensus and divergence in the current landscape of CCT utilization. ESC and ACC/AHA guidelines were systematically reviewed for CCT recommendations. The class of recommendation (COR) and level of evidence (LOE) were compared using χ2 or Fisher exact tests. The latest ESC guidelines included 40 recommendations regarding CCT: 18 (45%) COR-I, 14 (35%) COR-IIa, 6 (15%) COR-IIb, and 2 (5%) COR-III. Two (5%) recommendation had LOE-A, 20 (50%) had LOE-B, and 18 (45%) had LOE-C. The latest ACC/AHA guidelines consisted of 54 recommendations: 18 (33.3%) COR-I, 28 (51.9%) COR-IIa, 6 (11.1%) COR-IIb, and 2 (3.7%) COR-III. Two recommendations were assigned LOE-A (3.7%), 30 (55.6%) were classified as LOE-B, and 22 (40.7%) as LOE-C. ACC/AHA guidelines had a significantly higher proportion of COR-IIa recommendations (P = 0.04) and similar proportions of COR-I and COR-IIb recommendations (P = 0.28; P = 0.76), compared to ESC guidelines. The proportion of LOE-B and LOE-C recommendations weren't statistically different (P = 0.54; P = 0.84). ACC/AHA guidelines included more CCT recommendations with a higher COR and LOE than ESC guidelines. These findings highlight the need for continued research and consensus-building to establish standardized, evidence-based CCT recommendations in clinical practice.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"933-941"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anan Abu Rmilah, Ramy Ghaly, Carlos Pfeiffer, Mohamed H Saeed, Abdulrahman Khojah, Suhaib Jaber, Hossam Alzu'Bi, Aziz Tabash, Anjula Chib, Raed Darwish, Larry Prokop, Tarec K Elajami, Reza Arsanjani
{"title":"Prognostic value of baseline RV dysfunction using TAPSE and TAPSE to PASP ratio in patients undergoing mitra-clip: a systematic review and meta-analysis.","authors":"Anan Abu Rmilah, Ramy Ghaly, Carlos Pfeiffer, Mohamed H Saeed, Abdulrahman Khojah, Suhaib Jaber, Hossam Alzu'Bi, Aziz Tabash, Anjula Chib, Raed Darwish, Larry Prokop, Tarec K Elajami, Reza Arsanjani","doi":"10.1007/s10554-025-03354-5","DOIUrl":"10.1007/s10554-025-03354-5","url":null,"abstract":"<p><p>Mitra-clip is an established therapy for high-risk surgical candidates who are refractory to optimal medical treatment. Reports have shown that right ventricular dysfunction (RVD) has been associated with increased morbidity and mortality in heart failure (HF) patients. Our goal of this systematic review/meta-analysis is to assess the prognosis of baseline RV function markers including TAPSE (tricuspid annular plane systolic excursion) and TAPSE:PASP (pulmonary artery systolic pressure) ratio after Mitra-clip. MEDLINE and EMBASE were searched from inception to December 20th, 2023, for studies discussing the prognostic outcome of pre-existing RVD in Mitra-clip patients. Definition of RV dysfunction was reported as an abnormal TAPSE (< 15-16 mm) or RV-PA (right ventricle-pulmonary artery) uncoupling expressed as abnormal TAPSE:PASP ratio (< 0.30-0.37 mm/mmHg). We included all original research studies (excluding reviews, meta-analysis, commentaries/editorials, and animal studies) that assessed the prognostic utility of TAPSE and TAPSE:PASP ratio in patients with MR undergoing Mitra-clip. Reviewers independently screened the studies and extracted the pertinent data. Odds ratios (OR) were calculated using a random-effects model. Twelve reports enrolling 3526 patients were included. Mean age ranged from 70 to 81 years and 61.1% patients were male. Primary, secondary, and mixed MR were reported in 36.9%, 61.4%, and 1.8% respectively. Mean LVEF ranged from 27% to 57.1% and 93.7% of patients had MR grade ≥ 3 + (at least moderate to severe MR). Patients with RVD had a reduction in the overall survival (OS) after Mitra-clip at 6 months (81.8% vs 90.5%, OR = 0.45 [0.35-0.58]; P < 0.001), 1-year (71.1% vs 85.7%, OR = 0.40 [0.33-0.48]; P < 0.001), and 2-year (60.3% vs 76.8%, OR = 0.37 [0.31-0.45]; P < 0.001) compared to normal RV group. Likewise, HF re-admission free survival was minimized among RVD patients at 6 months (76.8% vs 88.1%, OR = 0.47 [0.34-0.65]; P < 0.001), 1-year (64.5% vs 81.3%, OR = 0.44 [0.35-0.55]; P < 0.001), and 2-year (58.2% vs 78.9%, OR = 0.41 [0.30-0.56]; P < 0.001) compared to normal RV group. Decreased TAPSE: PASP was associated with lower OS at 6-month (OR = 0.46 [0.31-0.68]; P < 0.001), 1-year (OR = 0.37 [0.29-0.47]; P < 0.001), and 2-year (OR = 0.35 [0.25-0.47]; P < 0.001) and reduced HF re-admission free survival at 6-month ((OR = 0.44 [0.31-0.62]; P < 0.001), 1-year (OR = 0.41[0.31-0.54]; P < 0.001), and 2-year (OR = 0.41 [0.31-0.58]; P < 0.001) after Mitra-clip. Furthermore, decreased TAPSE negatively impacted the OS and HF re-admission at 6-month (OR = 0.40 [0.21-0.77]; P = 0.006), and 1-year (OR = 0.50 [0.31-0.80]; P = 0.004) and increased HF re-admission rate at 6-month (OR = 0.27 [0.13-0.56]; P = 0.0005), and 1-year (OR = 0.30 [0.15-0.58]; P = 0.0004). Pre-existing RVD as expressed by TAPSE < 15-16 mm or TAPSE:PASP ratio < 0.30-0.37 mmHg reduced the OS and HF readmission free survival after Mitra-clip.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"827-846"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unmasking cardiac rhythm disorders through the Lens of non-invasive imaging: the arrhythmia section of IJCVI.","authors":"Anna Giulia Pavon","doi":"10.1007/s10554-025-03406-w","DOIUrl":"https://doi.org/10.1007/s10554-025-03406-w","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":"41 5","pages":"823-824"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John P Farrant, Nicholas Black, Kentaro Yamagata, Fardad Soltani, Christopher Orsborne, Chi Kit Yan, David Clark, Luke Pleva, Clifford Garratt, Matthias Schmitt, Bernard Clarke, Josephine Naish, Anna Reid, Christopher A Miller
{"title":"Comprehensive reference ranges for cardiovascular magnetic resonance: time to move on from single centre data?","authors":"John P Farrant, Nicholas Black, Kentaro Yamagata, Fardad Soltani, Christopher Orsborne, Chi Kit Yan, David Clark, Luke Pleva, Clifford Garratt, Matthias Schmitt, Bernard Clarke, Josephine Naish, Anna Reid, Christopher A Miller","doi":"10.1007/s10554-025-03370-5","DOIUrl":"10.1007/s10554-025-03370-5","url":null,"abstract":"<p><p>Cardiovascular magnetic resonance (CMR) provides gold standard, and often unique, measurements of cardiovascular structure, function and tissue character. Fundamental to such capabilities are clearly defined normal ranges. This study aimed to (1) Determine normal ranges for an extensive set of CMR measurements, and the inter-scan reproducibility of these measurements; (2) Determine the impact of common variations in practice, and; (3) Systematically evaluate the findings in the context of published reference ranges. One hundred and 22 healthy adults, including a minimum of 10 males and 10 females per age decile, underwent assessment including CMR (3 T, Siemens). Twenty participants returned for a second CMR. Image analysis was performed using cvi42 by experienced observers. Age- and sex-specific reference ranges, in tabular and normogram formats, and their interscan reproducibility, are provided for left ventricular mass, wall thickness, volumes and ejection fraction; right ventricular volumes and ejection fraction; longitudinal, radial and circumferential LV strains; atrial area, volume and strains; native T1, T2, T2*, aortic distensibility and pulse wave velocity. Measurement reproducibility improved when baseline scans were used for reference, e.g., for basal slice selection. Myocardial T1 was the most reproducible of all CMR measurements. Common variations in practice resulted in significant measurement differences e.g., indexed left atrial volume was larger (47.3 vs 40.3 ml/m<sup>2</sup>, P < 0.0001), and its measurement less variable, when measured from atrial short-axis cine stacks compared to biplanar measurement from 4- to 2-chamber cines. Studies using similar methods to define normal ranges demonstrate clinically-relevant differences in the normal ranges produced. A comprehensive set of age and sex specific CMR reference ranges are provided, along with inter-scan reproducibility and the impact of common variations in practice. Single centre studies, whilst meticulous in design and delivery, result in clinically-relevant variations in normal ranges. We advocate that larger cohorts, including diverse ethnicities, such as the Healthy Hearts Consortium, may be a better approach to defining normal ranges for common CMR measurements.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"913-932"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Musso, Anne-Lise Hachulla, Christoph Gräni
{"title":"The forgotten bullet: a rare coronary-CT image discovery.","authors":"Philippe Musso, Anne-Lise Hachulla, Christoph Gräni","doi":"10.1007/s10554-025-03374-1","DOIUrl":"10.1007/s10554-025-03374-1","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1007-1008"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yang Chen, Hong Yu, Bin Fan, Yong Wang, Zhibo Wen, Zhihui Hou, Jihong Yu, Haiping Wang, Zhe Tang, Ning Li, Peng Jiang, Yang Wang, Weihua Yin, Bin Lu
{"title":"Diagnostic performance of deep learning-based coronary computed tomography angiography in detecting coronary artery stenosis.","authors":"Yang Chen, Hong Yu, Bin Fan, Yong Wang, Zhibo Wen, Zhihui Hou, Jihong Yu, Haiping Wang, Zhe Tang, Ning Li, Peng Jiang, Yang Wang, Weihua Yin, Bin Lu","doi":"10.1007/s10554-025-03383-0","DOIUrl":"10.1007/s10554-025-03383-0","url":null,"abstract":"<p><strong>Purpose: </strong>To validate a fully automated, deep learning model based on coronary computed tomography angiography (CCTA) for the diagnosis of obstructive coronary artery disease (CAD) with stenosis ≥ 50%, which is commonly used as a clinical threshold for further testing and management. This model aims to improve diagnostic efficiency by automating the identification of significant coronary stenosis(≥ 50%).</p><p><strong>Methods: </strong>This multicenter clinical trial included patients been undergone CCTA from October 13, 2022, to February 28, 2023. CCTA data from suspected coronary artery disease (CAD) patients were retrospectively analyzed using deep learning-based software for comprehensive assessment, including coronary segmentation, lumen, and stenosis determination with comparison to the reference standard of consensus by three experts. This study utilized a multi-stage deep learning framework for coronary artery segmentation and stenosis analysis from CCTA images, consisting of several key components, including the 3D Multi-resolution Cascade Convolutional Neural Network (CNN), 3D Cascade-Locally Optimized Network, and Stenosis Analysis Network. The clinical trial registry number was NCT06172985.</p><p><strong>Results: </strong>A total of 1090 patients (mean age: 59.90 ± 11.51 years, 47.3% female) were included in this multicenter study. Artificial intelligence (AI) demonstrated excellent performance at the patient level, accurately diagnosing ≥ 50% stenosis by assessing each patient's coronary artery condition. The AI system showed high values for accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). The values of the above statistics were 92.8%, 95.3%, 91.4%, 85.6%, and 97.3%, respectively. Excellent agreement was seen between expert readers and deep learning-determined maximal diameter stenosis for per-patient (kappa coefficients: 0.84, 95%CI: 0.81-0.88). Regarding diagnostic efficiency, comparing the AI with expert readers, the average reading time decreased from 5.94 min to 2.01 min (p < 0.001).</p><p><strong>Conclusion: </strong>A novel AI-based assessment of CCTA can accurately and rapidly identify patients with coronary artery stenosis ≥ 50%, aiding in effective triage within the defined study population.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"979-989"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Leite, Eduardo Vilela, Jorge Oliveira, Ricardo Fontes-Carvalho
{"title":"Positional mitral regurgitation: a dynamic phenomenon.","authors":"Marta Leite, Eduardo Vilela, Jorge Oliveira, Ricardo Fontes-Carvalho","doi":"10.1007/s10554-025-03364-3","DOIUrl":"10.1007/s10554-025-03364-3","url":null,"abstract":"<p><p>Mitral regurgitation (MR) is a dynamic condition influenced by positional changes and physical stress. We report a case of severe positional MR in a 74-year-old woman with dilated cardiomyopathy, highlighted by echocardiographic findings of leaflet tethering and restricted mobility. Upright positioning significantly alleviated symptoms and MR severity, underscoring the impact of hemodynamic factors on its clinical presentation.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1005-1006"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Takotsubo cardiomyopathy after orthotopic liver transplantation.","authors":"Maham Jehangir","doi":"10.1007/s10554-025-03350-9","DOIUrl":"10.1007/s10554-025-03350-9","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy (TC), a reversible condition often triggered by stress, is characterized by left ventricular (LV) dysfunction in the absence of obstructive coronary artery disease (CAD). This condition is rare after orthotopic liver transplantation (OLT). Imaging is crucial to diagnosis.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1015-1017"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}