The international journal of cardiovascular imaging最新文献

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Resting myocardial strain derived from gated SPECT and its associations with ventricular remodeling, synchrony, perfusion and function. 门控SPECT获得的静息心肌应变及其与心室重构、同步、灌注和功能的关系。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-16 DOI: 10.1007/s10554-026-03826-2
Guillermo Romero-Farina, Santiago Aguadé-Bruix, C David Cooke, Ignacio Ferreira-González, Ernest V Garcia
{"title":"Resting myocardial strain derived from gated SPECT and its associations with ventricular remodeling, synchrony, perfusion and function.","authors":"Guillermo Romero-Farina, Santiago Aguadé-Bruix, C David Cooke, Ignacio Ferreira-González, Ernest V Garcia","doi":"10.1007/s10554-026-03826-2","DOIUrl":"https://doi.org/10.1007/s10554-026-03826-2","url":null,"abstract":"<p><p>To evaluate the association between resting myocardial strain derived from gSPECT-MPI and left ventricular (LV) remodeling, mechanical dyssynchrony, myocardial perfusion, and LV function. We retrospectively analyzed 131 consecutive patients (age 64.07 ± 11 years; 63.36% men) who underwent resting gSPECT-MPI with myocardial strain analysis using StrainTool™ (Emory Cardiac Toolbox™). Global longitudinal (GLS), circumferential (GCS), and radial strain (GRS), LV function, remodeling, mechanical synchrony, and myocardial perfusion were assessed. Pearson and Spearman correlations and univariable and multivariable linear regression analyses were performed. GLS, GCS, and GRS showed significant Pearson and Spearman correlations with parameters of LV remodeling, mechanical synchrony, myocardial perfusion, and LV function. In multivariable linear regression analysis, LV mass (p = 0.031), LV ejection fraction (LVEF) (p < 0.001), and the end-systolic (p = 0.008) and end-diastolic (p = 0.022) eccentricity indices were independently associated with GLS (R² = 0.86; p < 0.001). Similarly, LVEF (p < 0.001) and the end-systolic and end-diastolic shape indices (both p < 0.001) were independently associated with GCS (R² = 0.84; p < 0.001). LVEF (p < 0.001) was independently associated with GRS (R² = 0.65; p < 0.001). Myocardial strain derived from resting gSPECT-MPI was associated with multiple markers of ventricular function, remodeling, mechanical synchrony, and myocardial perfusion. The distinct patterns of association observed for GLS, GCS, and GRS provide further insight into the relationships between myocardial deformations and conventional gSPECT-MPI parameters.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of CT-derived interarterial and intramural anomalous coronary arteries anatomy compared with 3D-reconstructed IVUS in-vivo reference. ct衍生的动脉间和壁内异常冠状动脉解剖与3d重建IVUS体内参考的准确性比较。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-16 DOI: 10.1007/s10554-026-03820-8
Anselm W Stark, Ali Mokhtari, Ryota Kakizaki, Marius R Bigler, Marc Ilic, Afreed Ashraf, Kiril Stoyanov, Christoph Ryffel, Lorenz Räber, Isaac Shiri, Christoph Gräni
{"title":"Accuracy of CT-derived interarterial and intramural anomalous coronary arteries anatomy compared with 3D-reconstructed IVUS in-vivo reference.","authors":"Anselm W Stark, Ali Mokhtari, Ryota Kakizaki, Marius R Bigler, Marc Ilic, Afreed Ashraf, Kiril Stoyanov, Christoph Ryffel, Lorenz Räber, Isaac Shiri, Christoph Gräni","doi":"10.1007/s10554-026-03820-8","DOIUrl":"https://doi.org/10.1007/s10554-026-03820-8","url":null,"abstract":"<p><p>In anomalous aortic origin of a coronary artery (AAOCA), coronary CT angiography (CCTA) is the primary tool for anatomical assessment. However, CCTA measurements lack validation against a high-resolution in-vivo standard. To assess CCTA reliability for lumen dimensions and intramural length (IML) in AAOCA, and to validate these against a three-dimensionally reconstructed intravascular ultrasound (3D-IVUS) reference using three additional IML methodologies. A total of 60 AAOCA patients with an interarterial/intramural course underwent both CCTA and IVUS. A 3D-IVUS was constructed and its geometric reproducibility assessed. CCTA reliability and agreement with 3D-IVUS were evaluated for ostial dimensions, position-dependent minimal lumen area (MLA), and IML, measured by interluminal space thickness (ILS), elliptic ratio, and pericoronary fat sign. 3D-IVUS reference standard showed excellent geometric reproducibility (median point-wise distance 0.19 mm, 95%CI 0.07-0.43 mm) and good-to-excellent intrareader reliability (ICC 0.72-0.96). CCTA intra- and inter-reader reliability was moderate-to-excellent for ostial parameters and ILS-derived IML (ICC 0.69-0.92) and poor-to-good for MLA (ICC 0.28-0.87). Against 3D-IVUS, CCTA ostial area demonstrated moderate correlation (r = 0.73, p < 0.001) with minimal bias, and ILS-derived IML showed moderate agreement (r = 0.59; bias + 0.23 mm), while the fat sign substantially overestimated length (+ 7.88 mm). Using 3D-IVUS as an in-vivo reference standard for the precise assessment of coronary anatomy in AAOCA, CCTA provided reproducible ostial measurements, and the ILS-based method showed the best performance among the evaluated CCTA approaches for estimating intramural length. However, wide limits of agreement preclude precise individual sizing, and position-dependent MLA measurements remain unreliable.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the comment by Yamaguchi et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis. 对Yamaguchi等人评论的回应:ct衍生的细胞外体积和严重主动脉瓣狭窄的预测目标。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-16 DOI: 10.1007/s10554-026-03828-0
Rita Almeida Carvalho, Márcia Presume, Pedro M Lopes, Pedro Freitas, António M Ferreira
{"title":"Response to the comment by Yamaguchi et al.: CT-derived extracellular volume and the prediction target in severe aortic stenosis.","authors":"Rita Almeida Carvalho, Márcia Presume, Pedro M Lopes, Pedro Freitas, António M Ferreira","doi":"10.1007/s10554-026-03828-0","DOIUrl":"https://doi.org/10.1007/s10554-026-03828-0","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative coronary artery and aortic valve calcification by virtual non-contrast Images from dual-energy delayed CT scans in patients with severe aortic stenosis. 严重主动脉狭窄患者双能延迟CT扫描虚拟非对比图像定量冠状动脉和主动脉瓣钙化。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-11 DOI: 10.1007/s10554-026-03822-6
Hidesato Fujito, Kaveh Rezaei Bookani, Bashaer Gheyath, Sunam Lee, Sung Woo Cho, Balaji Tamarappoo, Alan C Kwan, Raj Makkar, Damini Dey, Piotr Slomka, Daniel S Berman, John Friedman, Donghee Han
{"title":"Quantitative coronary artery and aortic valve calcification by virtual non-contrast Images from dual-energy delayed CT scans in patients with severe aortic stenosis.","authors":"Hidesato Fujito, Kaveh Rezaei Bookani, Bashaer Gheyath, Sunam Lee, Sung Woo Cho, Balaji Tamarappoo, Alan C Kwan, Raj Makkar, Damini Dey, Piotr Slomka, Daniel S Berman, John Friedman, Donghee Han","doi":"10.1007/s10554-026-03822-6","DOIUrl":"https://doi.org/10.1007/s10554-026-03822-6","url":null,"abstract":"<p><p>With the growing use of delayed dual-energy computed tomography (DECT) imaging for extracellular volume assessment, this study aimed to assess the accuracy of coronary artery calcium (CAC) and aortic valve calcification (AVC) quantification in virtual non-contrast (VNC) images derived from delayed DECT images. Eighty-eight patients undergoing pre-transcatheter aortic valve replacement (TAVR) cardiac CTA with DECT were retrospectively enrolled. We compared CAC score (CACS), CAC volume, AVC score (AVCS), and AVC volume between true non-contrast (TNC) and VNC images. VNC images were created by subtracting iodine from delayed CT angiography using commercial post-processing software. Concordance for the likelihood of severe aortic stenosis (AS) between TNC and VNC was assessed using guideline-based AVCS thresholds: men > 3,000 AU, women > 1,600 AU (highly likely); men > 2,000 AU, women > 1,200 AU (likely). CACS was lower in VNC than TNC (363.0 [13.7-1,154.0] AU vs. 470.1 [46.8-1,569.9] AU, p < 0.001), but the correlation was excellent (r = 0.966). No significant difference between VNC and TNC was observed in AVCS (959.5 [321.2-2,475.0] AU vs. 1,079.6 [492.2-2,329.4] AU, p = 0.521), with strong correlation (r = 0.966). Application of a correction factor (1.1-fold) improved agreement between VNC- and TNC-derived CACS (weighted κ = 0.839 to 0.869). Diagnostic concordance for severe AS between VNC and TNC was 92.1% (weighted kappa = 0.785) at the \"highly likely\" threshold and 97.7% (weighted kappa = 0.952) at the \"likely\" threshold. Delayed VNC images from DECT demonstrate strong agreement with TNC images for CACS and AVCS, suggesting that delayed VNC could potentially reduce the need for TNC acquisition in pre-TAVR assessment.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redefining NSTE-ACS risk assessment: The synergistic power of CT-enhanced GRACE 2.0 score for advanced prognosis. 重新定义NSTE-ACS风险评估:ct增强GRACE 2.0评分对晚期预后的协同作用
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-06 DOI: 10.1007/s10554-026-03811-9
Jing-Wen Ma, Shan Muhammad, U Joseph Schoepf, Chuang-Shi Wang, Zhi-Hui Hou, Yun-Qiang An, Er-Li Zhang, Yan Liang, Zhou Zhou, Ya-Hui Lin, Wei-Hua Yin, Bin Lu
{"title":"Redefining NSTE-ACS risk assessment: The synergistic power of CT-enhanced GRACE 2.0 score for advanced prognosis.","authors":"Jing-Wen Ma, Shan Muhammad, U Joseph Schoepf, Chuang-Shi Wang, Zhi-Hui Hou, Yun-Qiang An, Er-Li Zhang, Yan Liang, Zhou Zhou, Ya-Hui Lin, Wei-Hua Yin, Bin Lu","doi":"10.1007/s10554-026-03811-9","DOIUrl":"https://doi.org/10.1007/s10554-026-03811-9","url":null,"abstract":"<p><p>The Global Registry of Acute Coronary Events (GRACE) 2.0 risk score has been recommended in guidelines to orient therapeutic strategy and risk assessment for non-ST-segment elevation acute coronary syndrome (NSTE-ACS). To evaluate the incremental value of computed tomography (CT)-based coronary atherosclerosis plaque burden to GRACE 2.0 score in refining the intermediate-term prognostic accuracy and risk stratification for emergency NSTE-ACS. In this prospective cohort study, from January 2017 to January 2021, NSTE-ACS individuals were enrolled and randomly divided into a developing and validation sets by 7:3. We estimated the correlations between GRACE 2.0 score and CT findings. The primary outcomes are the incremental prognostic value of CT for the GRACE 2.0 score's efficacy in predicting 3-year mortality or myocardial infarction (MI). A total of 1248 consecutive NSTE-ACS patients undergoing CT scans were prospectively included. The risk of 3-year mortality or MI was greater in the higher CACS category (HR, 2.31 [95% CI, 1.45-3.67]), SIS category (HR, 3.37 [95% CI, 2.36-4.82]) and luminal stenosis degree (HR, 1.69 [95% CI, 1.15-2.48]) stratified by CAD-RADS (coronary artery disease reporting and Data System) 2.0 than in the lower ones. The CT-GRACE model integrating CACS category, SSS and GRACE 2.0 risk score was compared with the GRACE 2.0 risk score to evaluate their discrimination and reclassification ability in predicting 3-year mortality or MI. The C-statistics were 0.889 (0.842, 0.937) and 0.742 (0.659, 0.826) in the validation set, respectively (ΔAUC=0.147, P < 0.001). Coronary atherosclerosis plaque burden features could provide more meaningful information for GRACE 2.0 risk score to evaluate the intermediate-term prognosis for emergency NSTE-ACS.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic performance of quantitative flow ratio against intravascular ultrasound in left main coronary artery disease: a prospective single-centre study. 定量血流比对血管内超声在左主干冠状动脉疾病中的诊断性能:一项前瞻性单中心研究
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-05 DOI: 10.1007/s10554-026-03818-2
İskan Zengin, Fuat Polat, Deniz Elçik, Erlan Abibulaev, Ramazan Ozan, Rıdvan Yurt, Nihat Kalay, Saban Keleşoğlu, Cuma Süleymanoğlu, İsmail Düzgün, Namık Kemal Eryol
{"title":"Diagnostic performance of quantitative flow ratio against intravascular ultrasound in left main coronary artery disease: a prospective single-centre study.","authors":"İskan Zengin, Fuat Polat, Deniz Elçik, Erlan Abibulaev, Ramazan Ozan, Rıdvan Yurt, Nihat Kalay, Saban Keleşoğlu, Cuma Süleymanoğlu, İsmail Düzgün, Namık Kemal Eryol","doi":"10.1007/s10554-026-03818-2","DOIUrl":"https://doi.org/10.1007/s10554-026-03818-2","url":null,"abstract":"<p><p>Accurate assessment of left main coronary artery (LMCA) disease is essential for guiding revascularization. Intravascular ultrasound (IVUS) is the reference standard for anatomical evaluation of intermediate LMCA stenosis, whereas quantitative flow ratio (QFR) is an angiography-derived, wire-free physiological index. Data comparing these modalities in LMCA disease remain limited. This prospective single-center study included 135 patients with LMCA lesions undergoing coronary angiography and IVUS between January 2024 and June 2025. Offline QFR was calculated using QAngio XA 3D. Significant LMCA disease was defined as IVUS-derived minimum lumen area (MLA) < 6 mm² or QFR < 0.80. Agreement, correlation, and diagnostic performance of QFR were evaluated against IVUS. The mean age was 63.4 ± 9.7 years, and 88.1% were male. IVUS identified significant LMCA disease in 92 patients (68.1%) versus 50 (37.0%) by QFR. Agreement was moderate (κ = 0.426, 95% CI 0.197-0.656; p = 0.0003). Using IVUS as the reference, QFR showed 54.3% sensitivity and 100% specificity. QFR correlated moderately with IVUS-derived MLA (r = - 0.416, p < 0.001) but consistently underestimated vessel dimensions (all p < 0.001). On multivariable analysis, QFR < 0.80 (OR 3.52, 95% CI 1.07-11.57; p = 0.039) and distal LMCA bifurcation lesions (OR 2.41, 95% CI 1.03-5.64; p = 0.043) independently predicted IVUS-defined significant disease. QFR demonstrated moderate concordance with IVUS but limited sensitivity, particularly in distal bifurcation lesions, and underestimated vessel dimensions. These findings limit its utility for LMCA procedural planning and stent optimization, highlighting the need for larger multicenter prospective studies.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex differences in coronary plaque stabilization with evolocumab: a post hoc analysis of the YELLOW III trial. evolocumab在冠状动脉斑块稳定中的性别差异:对YELLOW III试验的事后分析
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-05 DOI: 10.1007/s10554-026-03824-4
Keisuke Yasumura, Sarah Goldman, Yuliya Vengrenyuk, JiaJia Liu, Pruthvi C Revaiah, Amit Hooda, Raman Sharma, Sahil Khera, Vishal Kapur, Joseph Sweeny, Prakash Krishnan, Pedro Moreno, Xiaobo Zhou, Jagat Narula, Roxana Mehran, Samin Sharma, Annapoorna S Kini
{"title":"Sex differences in coronary plaque stabilization with evolocumab: a post hoc analysis of the YELLOW III trial.","authors":"Keisuke Yasumura, Sarah Goldman, Yuliya Vengrenyuk, JiaJia Liu, Pruthvi C Revaiah, Amit Hooda, Raman Sharma, Sahil Khera, Vishal Kapur, Joseph Sweeny, Prakash Krishnan, Pedro Moreno, Xiaobo Zhou, Jagat Narula, Roxana Mehran, Samin Sharma, Annapoorna S Kini","doi":"10.1007/s10554-026-03824-4","DOIUrl":"https://doi.org/10.1007/s10554-026-03824-4","url":null,"abstract":"<p><p>Whether coronary plaque response to proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition differs by sex remains uncertain. We assessed sex-related differences in serial intravascular imaging and transcriptomic responses to evolocumab. This post hoc analysis of the YELLOW III trial included 110 patients with chronic coronary disease (CCD) receiving maximally tolerated statin therapy who had lipid-rich, non-obstructive coronary lesions on optical coherence tomography (OCT). All received evolocumab 140 mg every 2 weeks for 26 weeks. Serial OCT, near-infrared spectroscopy, and intravascular ultrasound were performed at baseline and follow-up. Peripheral blood mononuclear cells underwent RNA sequencing. Among 110 patients, 29 were women and 81 were men. Absolute low-density lipoprotein cholesterol reduction did not differ significantly between women and men (-56.6 ± 35.9 vs. -58.1 ± 26.4 mg/dL; p = 0.830). Plaque response did not differ significantly by sex for minimum fibrous cap thickness (+ 27.9 ± 26.5 vs. + 26.4 ± 20.7 μm; p = 0.755), maximum lipid core burden index within a 4-mm segment (-86.8 ± 158.6 vs. -96.2 ± 134.4; p = 0.756), and percent atheroma volume (-1.2 ± 1.1 vs. -1.5 ± 1.6%; p = 0.353). At baseline, 2,650 genes were differentially expressed, with neutrophil degranulation and nuclear factor-κB-related inflammatory pathways upregulated in men. At follow-up, 301 genes were differentially expressed, and the baseline inflammatory pathway differences were attenuated. Evolocumab was associated with similar short-term plaque stabilization in women and men with CCD, despite baseline sex-related differences in inflammatory pathways. These findings warrant confirmation in larger prospective studies.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative intramyocardial hemorrhage assessment by conventional T2-weighted imaging improves risk stratification in reperfused STEMI. 通过常规t2加权成像定量评估心内出血可改善STEMI再灌注的风险分层。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-03 DOI: 10.1007/s10554-026-03812-8
Zhi Li, Zhuang Chen, Min Zhang, Lei Chen, Yiwen Wang, Weiwei Sha, Dongchen Liu, Yixuan Wu, Yu Yang, Yuan Lu
{"title":"Quantitative intramyocardial hemorrhage assessment by conventional T2-weighted imaging improves risk stratification in reperfused STEMI.","authors":"Zhi Li, Zhuang Chen, Min Zhang, Lei Chen, Yiwen Wang, Weiwei Sha, Dongchen Liu, Yixuan Wu, Yu Yang, Yuan Lu","doi":"10.1007/s10554-026-03812-8","DOIUrl":"https://doi.org/10.1007/s10554-026-03812-8","url":null,"abstract":"<p><p>Intramyocardial hemorrhage (IMH), a severe reperfusion injury, is optimally detected by T2* mapping, which remains limited by sensitivity to artifacts and relatively long acquisition times. We aimed to evaluate the prognostic value of IMH identified by conventional T2-weighted (T2W) imaging in patients with ST-elevation myocardial infarction (STEMI). In this single-center retrospective study, 453 STEMI patients underwent CMR at a median of 5 days post-reperfusion. IMH was identified quantitatively as a hypointense core within edema on T2W imaging and expressed as a percentage of left ventricular mass. The primary endpoint was a composite of all-cause death and heart failure hospitalization. IMH was present in 167 patients (36.9%). Over a median follow-up of 25 months, 49 patients (10.8%) experienced MACE. Those with MACE had a higher prevalence of IMH (75.5% vs. 32.2%, p < 0.001). Multivariable Cox regression identified IMH extent ≥ 1.0% of LV mass as a strong and independent predictor of MACE (HR 1.14, 95% CI 1.07-1.21, p < 0.001). Adding quantitative IMH to a base model (anterior infarction, IS, MVO, LVEF) significantly improved prognostic performance: AUC increased from 0.800 to 0.828, with net reclassification improvement of 12% (p < 0.001) and integrated discrimination improvement of 7% (p = 0.018). In this selected cohort, quantitative IMH assessment using conventional T2W imaging provides significant incremental prognostic value beyond traditional risk factors in STEMI patients, enabling improved risk stratification with a widely available CMR sequence.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Foetal detection of a mitral leaflet mass. 胎儿检测二尖瓣小叶肿块。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-01 Epub Date: 2026-03-09 DOI: 10.1007/s10554-026-03675-z
Francesca Bonanni, Adalgisa Cordisco, Giovanni Battista Calabri, Iacopo Olivotto, Silvia Favilli
{"title":"Foetal detection of a mitral leaflet mass.","authors":"Francesca Bonanni, Adalgisa Cordisco, Giovanni Battista Calabri, Iacopo Olivotto, Silvia Favilli","doi":"10.1007/s10554-026-03675-z","DOIUrl":"10.1007/s10554-026-03675-z","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1829-1830"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When non-significance is not robustness: Interpreting left atrial strain in the presence of left bundle branch block. 当不显著性不是稳健性时:左束支传导阻滞时左心房应变的解释。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-09-01 Epub Date: 2026-08-03 DOI: 10.1007/s10554-026-03793-8
Güney Sarıoğlu
{"title":"When non-significance is not robustness: Interpreting left atrial strain in the presence of left bundle branch block.","authors":"Güney Sarıoğlu","doi":"10.1007/s10554-026-03793-8","DOIUrl":"10.1007/s10554-026-03793-8","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1819-1820"},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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