Sara Di Nicolantonio, Serena Altamura, Davide Pietropaoli, Annalisa Monaco, Eleonora Ortu
{"title":"Orthodontic treatment and oral microbiota changes: a systematic review of oral dysbiosis revealed by 16S rRNA gene analysis.","authors":"Sara Di Nicolantonio, Serena Altamura, Davide Pietropaoli, Annalisa Monaco, Eleonora Ortu","doi":"10.2319/112724-978.1","DOIUrl":"10.2319/112724-978.1","url":null,"abstract":"<p><strong>Objectives: </strong>Evaluate the changes in oral microbiota linked to orthodontic treatment by analyzing the 16S rRNA gene.</p><p><strong>Materials and methods: </strong>A total of 22 articles was included in the systematic review. The methodological quality of these studies was assessed using the Newcastle-Ottawa Scale for nonrandomized studies and the Risk of Bias tool for randomized studies.</p><p><strong>Results: </strong>Orthodontic appliances significantly influenced the composition of oral microbiota. Specifically, fixed orthodontic appliances were linked to an increase in periodontopathogenic bacteria associated with various systemic diseases. In contrast, transparent aligners correlated with an increase in Streptococcus species.</p><p><strong>Conclusions: </strong>In this study, we evaluated the changes in oral microbiota associated with orthodontic treatment by analyzing the 16S rRNA gene. Results revealed significant alterations in oral microbiota following orthodontic treatment; however, significant variability among studies prevents firm conclusions. Additional research is essential to clarify the effects on oral health.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Buse Nur Gok, Ahmet Yalcin Gungor, Ozge Erken Gungor
{"title":"Effect of clear aligners and Z-spring appliance on anterior crossbite correction and quality of life in the mixed dentition: a randomized clinical trial.","authors":"Buse Nur Gok, Ahmet Yalcin Gungor, Ozge Erken Gungor","doi":"10.2319/022125-154.1","DOIUrl":"https://doi.org/10.2319/022125-154.1","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the efficacy of clear aligners and Z-spring (ZS) appliances in treating dental anterior crossbite (AC) during the mixed dentition period.</p><p><strong>Materials and methods: </strong>Thirty patients (7-12 years) with Angle Class I occlusion and isolated pseudo-Class III AC were randomly assigned to clear aligners (Group A, n = 15) or ZS appliances (Group B, n = 15). Outcomes were evaluated based on duration, cephalometric changes, model analysis, and oral health-related quality of life (OHRQoL), assessed using the Child Oral Health Impact Profile-Short Form-19 (COHIP-SF-19).</p><p><strong>Results: </strong>AC was successfully corrected in all patients. Treatment duration was significantly shorter in Group B (48.4 ± 27 days) than in Group A (96.3 ± 22.7 days) (P < .05). U1-NA angle increased by 5.9° and overjet by 4 mm in Group A; in Group B, U1-NA increased by 7.7° and overjet by 4.2 mm (P < .01). Intergroup cephalometric changes (ΔT1-T0) were not significant (P > .05). In Group A, incisal and gingival arch depths increased significantly (2.6 mm and 1.17 mm, respectively; P < .001), whereas no significant changes occurred in Group B (P > .05). COHIP-SF-19 scores were comparable (P > .05).</p><p><strong>Conclusion: </strong>Clear aligners and ZS appliances were effective in treating dental AC, achieving normal overjet relationships. However, ZS appliances may cause greater tipping, whereas clear aligners facilitate tipping, alignment, and bodily movement. Treatments demonstrated comparable effects on OHRQoL of children. This study provides a foundation for future research on different appliances for managing AC in the mixed dentition.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra C Bachour, Robert T Klabunde, Thorsten Grünheid
{"title":"Usefulness of an artificial intelligence-assisted indirect bonding method for optimizing orthodontic bracket positioning.","authors":"Petra C Bachour, Robert T Klabunde, Thorsten Grünheid","doi":"10.2319/022425-157.1","DOIUrl":"https://doi.org/10.2319/022425-157.1","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the bracket positioning accuracy of a traditional and an artificial intelligence (AI)-assisted digital indirect bonding (IDB) method to explore the current usefulness of AI for optimizing orthodontic bracket positioning.</p><p><strong>Materials and methods: </strong>Twenty-five clinicians positioned brackets using traditional and AI-assisted digital IDB methods. Bracket positioning differences were quantified using digital superimposition of bracket setups and compared with an optimal setup. A total of 1800 bracket positioning differences were evaluated. One-tailed t-tests were used to determine whether these differences were within limits of 0.5 mm in mesial-distal and occlusal-gingival dimensions and within 2° for tip.</p><p><strong>Results: </strong>Overall mean bracket position differences between the traditional and digital setups were 0.28 mm for mesial-distal placement and 0.32 mm for occlusal-gingival placement; both were significantly below the 0.5-mm limit. In contrast, differences in tip were 3.4°, which was significantly greater than the 2° limit. Comparisons with an optimal setup showed overall statistically significant differences in mean bracket positioning for tip but not for the mesial-distal or occlusal-gingival measurements for both the traditional and AI-assisted digital IDB methods. However, the digital method was more accurate for bracket tip.</p><p><strong>Conclusions: </strong>Bracket positioning is consistent and highly accurate in linear dimensions with both traditional and digital IDB methods; however, AI may be useful for improving accuracy of bracket angulation. Clinicians who currently use traditional IDB methods may adopt AI-assisted digital IDB without compromising bracket positioning accuracy.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Rafaela Diniz, Dauro Douglas Oliveira, Lucas Guimarães Abreu, Ribeiro de Castro Ribeiro, Soraya de Mattos Camargo Grossmann
{"title":"Influence of social media on the choice of orthodontist and different types of orthodontic treatment.","authors":"Amanda Rafaela Diniz, Dauro Douglas Oliveira, Lucas Guimarães Abreu, Ribeiro de Castro Ribeiro, Soraya de Mattos Camargo Grossmann","doi":"10.2319/090424-727.1","DOIUrl":"https://doi.org/10.2319/090424-727.1","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate, from the perspective of patients, the influence of social media (SM) on the choice of orthodontist and the acceptance of orthodontic treatment (OT) proposed by a professional.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted using an online questionnaire that contained 17 items distributed across four sections. Individuals older than 18 years, who were treated or sought OT, and who had SM accounts were included. Data were collected via Google Forms using the snowball technique and subsequently analyzed using the Mann-Whitney U-test. Effect size (ES) was calculated (small, moderate, or large).</p><p><strong>Results: </strong>Of the 206 participants, 148 were women (71.8%), and 58 were men (28.2%), with a mean age of 37.3 ± 15.0 years. The most used SM applications were WhatsApp (95.1%), Instagram (92.2%), YouTube (56.8%), and Facebook (30.1%). Women respondents 36 years old or younger who were single and had no higher education showed a significant difference in choosing a professional and accepting OT on all questionnaire items (P < 0.001). Among SM platforms, Instagram was the one used most often to choose a professional and OT modality as well as considered important for revealing the professional's academic training. By contrast, WhatsApp was the least used for before-and-after posts, while YouTube was seldom used to evaluate posted comments. For variables with significant differences, the ES ranged from moderate to large.</p><p><strong>Conclusions: </strong>SM, especially Instagram, can influence decision-making when choosing an orthodontist and accepting the recommendations for OT proposed by a professional.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of aging and mechanical brushing on color stability and translucency of three-dimensionally printed and thermoformed aligners of different thicknesses.","authors":"Muhammet Fidan, Ibrahim Erhan Gelgor","doi":"10.2319/011325-50.1","DOIUrl":"https://doi.org/10.2319/011325-50.1","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the effect of aging and mechanical brushing on the color stability and translucency of three-dimensionally (3D) printed and thermoformed transparent aligners (clear aligners [CAs]) of different thicknesses.</p><p><strong>Materials and methods: </strong>Three types of CAs (Dentsply Sirona Essix [Group 1], Scheu-Dental Thermoforming Foils [Group 2], and 3D-printed Nexdent [Group 3]) in two thicknesses (0.75 mm and 1.0 mm) were used. Each group was divided into cleaned and noncleaned subgroups (n = 10). Samples were aged in artificial saliva and subjected to mechanical brushing. Color differences (ΔE00) and relative translucency parameter values (RTP00) were recorded at 1-week intervals over 4 weeks. Statistical analyses included generalized linear models and repeated measures analyses of variance (ANOVAs) for normally distributed parameters, and robust ANOVAs and Friedman tests for nonnormally distributed parameters (P < .05).</p><p><strong>Results: </strong>Group 1 had the highest mean RTP00 values, while Group 3 had the lowest mean RTP00 values. Noncleaned CAs exhibited higher RTP00 values than cleaned CAs (P < .05). RTP00 values decreased significantly over time, with Group 3 showing notable differences between cleaned and noncleaned subgroups. Thinner materials (0.75 mm) displayed greater color changes than thicker ones (1 mm).</p><p><strong>Conclusions: </strong>3D-printed CAs demonstrated more significant color variation and less translucency in comparison to thermoformed CAs. Regular cleaning helps maintain translucency and color stability, but the choice of aligner material is crucial.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunjay Suri, Suteeta Disthaporn, Wendy Lou, David Fisher
{"title":"Relation of maxillary permanent central incisor rotations with the primary palatal margin and overjet in repaired complete unilateral cleft lip and palate.","authors":"Sunjay Suri, Suteeta Disthaporn, Wendy Lou, David Fisher","doi":"10.2319/040724-278.1","DOIUrl":"https://doi.org/10.2319/040724-278.1","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the relation of maxillary permanent central incisor rotation with the primary palatal margin (PPM) and overjet in the mixed dentition in complete unilateral cleft lip and palate (cUCLP).</p><p><strong>Materials and methods: </strong>Dental casts and preorthodontic records taken before alveolar bone grafting were examined to exclude patients having permanent teeth distal to the cleft side maxillary central incisor (CS1) and mesial to the cleft. Maxillary central incisor rotation, the angle between PPM and midline, proximity of the lingual surface of the central incisor to PPM, and overjet were measured from standardized occlusal photographs of the dental casts of 54 children with repaired cUCLP (38 M, 16 F; aged 8.7 ± 1.0 years). Descriptive analysis and correlation statistics were performed.</p><p><strong>Results: </strong>Rotations were noted in 92.6% of the CS1. Their magnitude (111.2 ± 24.2°) was significantly greater than the noncleft side maxillary central incisor (NCS1) rotations (76.7 ± 15.7°). Rotations were predominantly distolabial for the CS1 and distopalatal for the NCS1. The PPM was located within 2 mm of the lingual surface of the CS1 in 35.2% of the sample. Severe CS1 rotation existed in 48.2% of the sample and was significantly correlated with the PPM angle (r = 0.3; P = .046) and when its proximity to the PPM was within 2 mm (φ = 0.3; P = .028). Overjet was not significantly correlated with the magnitude of rotation.</p><p><strong>Conclusions: </strong>The angle between PPM and the midline and its proximity to CS1 are associated with the severity of CS1 rotation in repaired cUCLP. Orthodontic implications are discussed.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suteeta Disthaporn, Veerasathpurush Allareddy, Phimon Atsawasuwan, Min Kyeong Lee
{"title":"Effectiveness and accuracy of clear aligners in non-extraction Class II correction: a systematic review of maxillary molar distalization and rotation in the permanent dentition.","authors":"Suteeta Disthaporn, Veerasathpurush Allareddy, Phimon Atsawasuwan, Min Kyeong Lee","doi":"10.2319/011525-55.1","DOIUrl":"https://doi.org/10.2319/011525-55.1","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effectiveness and accuracy of clear aligners (CA) in maxillary molar distalization and rotation for nonextraction Class II correction in the permanent dentition.</p><p><strong>Materials and methods: </strong>This systematic review of the literature (2015-2024) followed PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines. Studies included orthodontic patients in the permanent dentition with dental Class II, mild or no skeletal discrepancies, 2-6 mm crowding, treated with CA without extractions (except maxillary third molars) or adjunctive therapies beyond Class II elastics. Data focused on maxillary molar distalization, rotation, accuracy, and complications. Risk of bias was assessed using ROBIN-I, with evidence level graded per the SBU protocol.</p><p><strong>Results: </strong>Sixteen studies were categorized into Group A (initial aligner or distalization outcomes) and Group B (including refinements). Group B reported greater accuracy and distalization due to sequential distalization protocols, Class II elastics, and refinements. After refinements, CA achieved 1.84-2.98 mm of maxillary molar distalization with 85% maximum accuracy. First-molar rotation reached 8.09°, with 78.4% maximum accuracy. No significant vertical skeletal changes were observed. Challenges included anterior anchorage loss, buccolingual tipping of upper molars, and patient compliance monitoring. Methodological variability and participant demographics prevented a meta-analysis.</p><p><strong>Conclusions: </strong>CA effectively achieves maxillary molar distalization and rotation in nonextraction Class II patients. Sequential distalization protocols and refinements improve treatment outcomes, whereas early incorporation of Class II elastics, combined molar movements, and compliance monitoring may enhance treatment efficiency.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synergistic effects of high-frequency vibration and orthodontic force on osteoclast numbers and root resorption in a rat model.","authors":"Luxkamon Luangthamma, Srisurang Suttapreyasri, Peungchaleoy Thammanichanon, Chidchanok Leethanakul","doi":"10.2319/010725-21.1","DOIUrl":"https://doi.org/10.2319/010725-21.1","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate how high-frequency vibration (125 Hz) combined with light or optimal orthodontic forces affects osteoclast numbers and root volume during tooth movement in Wistar rats.</p><p><strong>Materials and methods: </strong>Using a split-mouth design, 96 sites in male Wistar rats were randomly assigned to six groups: control, high-frequency vibration (HFV), light force (LF, 5g), light force with vibration (LF/HFV), optimal force (OF, 10g), and optimal force with vibration (OF/HFV). First maxillary molars were moved mesially using nickel-titanium (NiTi) closed coil springs. Root volume and osteoclast numbers were measured using Micro-CT and histomorphometry at Days 1, 7, 14, and 21.</p><p><strong>Results: </strong>After 21 days, osteoclast numbers increased significantly in HFV (5.25 ± 0.48, P =. 002), LF/HFV (10.00 ± 0.41, P < .0001), OF (13.75 ± 0.48, P <.0001), and OF/HFV (15.25 ± 0.85, P < .0001) groups. Root volume decreased significantly in LF/HFV (7.75 ± 0.18 mm3), OF (6.68 ± 0.24 mm3), and OF/HFV (6.28 ± 0.14 mm3) groups compared to control (all P < .0001). HFV alone increased osteoclast numbers but did not affect root volume. The OF/HFV group showed the highest osteoclast numbers and root volume reduction. Three-way analysis of variance revealed that time, vibration, and force significantly reduced root volume (P < .0001). Notably, the interaction effects on osteoclast numbers were significant in LF group (P < .0001), but not OF group (P = .338).</p><p><strong>Conclusions: </strong>Combined high-frequency vibration and orthodontic forces increased osteoclast numbers and root resorption. Light forces with high-frequency vibration promoted osteoclast formation while minimizing root resorption compared to optimal forces. Additionally, the duration of this combined treatment significantly affected the extent of root resorption.</p>","PeriodicalId":94224,"journal":{"name":"The Angle orthodontist","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}