Social cognitive and affective neuroscience最新文献

Individualized Theta Transcranial Alternating Current Stimulation Modulates Mnemonic Discrimination and ERP Responses to Positive Information in Individuals With Elevated Depressive Symptoms. 个体化Theta经颅交流电刺激调节抑郁症状升高个体对正面信息的记忆辨别和ERP反应。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-10-16 DOI: 10.1093/scan/nsag079

Xinyu Huang, Min Zhou, Chun Wang, Yuxin Huang, Wenchang Wang, Jianfei Shao, Junyu Mao, Jiaqi Li, Lei Zhang, Rong Ye, Chunyan Zhu, Yanghua Tian, Kongliang He, Fengqiong Yu, Kai Wang

{"title":"Individualized Theta Transcranial Alternating Current Stimulation Modulates Mnemonic Discrimination and ERP Responses to Positive Information in Individuals With Elevated Depressive Symptoms.","authors":"Xinyu Huang, Min Zhou, Chun Wang, Yuxin Huang, Wenchang Wang, Jianfei Shao, Junyu Mao, Jiaqi Li, Lei Zhang, Rong Ye, Chunyan Zhu, Yanghua Tian, Kongliang He, Fengqiong Yu, Kai Wang","doi":"10.1093/scan/nsag079","DOIUrl":"https://doi.org/10.1093/scan/nsag079","url":null,"abstract":"Individuals with elevated depressive symptoms often show impairments in positive memory processing. This randomized, double-blind study investigated whether individualized theta-frequency transcranial alternating current stimulation (tACS) using an OFC-oriented montage modulates mnemonic discrimination and ERP responses to positive information. Sixty-one individuals with elevated depressive symptoms received either real or sham stimulation before completing an emotional mnemonic discrimination task. Behavioral results showed that lure discrimination increased following real stimulation but not sham stimulation. EEG results showed that real stimulation modulated ERP responses during positive memory encoding and retrieval, as reflected by increased late positive potential (LPP) amplitudes during encoding and altered early retrieval-related ERP amplitudes. These findings suggest that individualized theta-tACS may influence both mnemonic discrimination performance and neural responses to positive information.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gentle grip of beauty: Neural bases of motor inhibition during aesthetic appreciation. 对美的温柔把握：审美过程中运动抑制的神经基础。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-10-07 DOI: 10.1093/scan/nsag084

Paolo Barbieri, Jacopo Frascaroli, Greta Varesio, Francesca Piovesan, Ludovico Bechis, Pietro Sarasso, Irene Ronga

{"title":"The gentle grip of beauty: Neural bases of motor inhibition during aesthetic appreciation.","authors":"Paolo Barbieri, Jacopo Frascaroli, Greta Varesio, Francesca Piovesan, Ludovico Bechis, Pietro Sarasso, Irene Ronga","doi":"10.1093/scan/nsag084","DOIUrl":"https://doi.org/10.1093/scan/nsag084","url":null,"abstract":"A century-old tradition characterizes aesthetic experiences as intense contemplative moments in which we suspend practical concerns and devote our full attention to the object at hand. In line with this tradition, recent theories suggest that aesthetic experiences involve heightened sensory processing accompanied by a suppression of motor activity. Yet, while the link between aesthetic appreciation and perceptual enhancement has received considerable attention, the role of motor inhibition remains largely unexplored. The present study addressed this gap by investigating whether the aesthetic appreciation of images can modulate behavioral and electrophysiological markers of motor inhibition. In Experiment 1, significantly slower reaction times following the observation of preferred images were found. In Experiment 2, EEG responses associated with motor preparation and execution were significantly reduced in trials involving preferred compared with non-preferred images. Time-frequency analysis revealed significantly decreased alpha power (associated with attentional engagement toward visual perception) and increased beta power (associated with inhibited motor preparation) for preferred than non-preferred images. Overall, our results provide new evidence for the existence of a relationship between aesthetic appreciation and motor inhibition and position aesthetic experience as a valuable case study for exploring the adaptive coordination of sensory and motor systems in response to environmental demands.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Warm pressure increases ventral striatum and mid-insula processing of social connection. 温压增加腹侧纹状体和中岛社会联系加工。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-09-15 DOI: 10.1093/scan/nsag077

Sarah J Dembling, Zoe F Damon, Annika C Linke, Molly Gonenne, Kylie Hawkins, Jacob Ross, Laura K Case, Tristen K Inagaki

{"title":"Warm pressure increases ventral striatum and mid-insula processing of social connection.","authors":"Sarah J Dembling, Zoe F Damon, Annika C Linke, Molly Gonenne, Kylie Hawkins, Jacob Ross, Laura K Case, Tristen K Inagaki","doi":"10.1093/scan/nsag077","DOIUrl":"https://doi.org/10.1093/scan/nsag077","url":null,"abstract":"Social touch is an underappreciated regulatory behavior that contributes to social connection. Apart from previous research on gentle stroking, scant research has systematically addressed the influence of sensory inputs on social connection and their underlying neural mechanisms. Previous research spanning non-human animal and human findings suggest that warmer and deeper pressure touch-as found during hand-holding, hugging, and swaddling-may enhance affective experience. The current study, therefore, investigates how temperature, pressure, and social context alter affective experience and neural activity. During a functional MRI scan, 66 participants experienced warm or neutral temperature packs and deeper or lighter pressure weighted blankets as they viewed images of close others and strangers. Warmth and deeper pressure together, compared to either alone, led to the greatest activity in the ventral striatum (VS) and mid-insula (MI), regions previously implicated in salience and interoceptive processing, while viewing images of close others, but not strangers. Compared to warmth and deeper pressure, connectivity between the VS and MI was weaker during neutral temperature and lighter pressure, suggesting different coupling of these regions during warm pressure. Results suggest a novel sensory-affective pathway underlying the processes that support social connection.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is damage to the ventromedial prefrontal cortex associated with impaired empathy? A neuropsychological study using an empathy motivation task. 腹内侧前额叶皮层的损伤与移情能力受损有关吗？一项使用移情动机任务的神经心理学研究。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-09-02 DOI: 10.1093/scan/nsag072

Julian A Scheffer, Justin Reber, C Daryl Cameron, Daniel Tranel

{"title":"Is damage to the ventromedial prefrontal cortex associated with impaired empathy? A neuropsychological study using an empathy motivation task.","authors":"Julian A Scheffer, Justin Reber, C Daryl Cameron, Daniel Tranel","doi":"10.1093/scan/nsag072","DOIUrl":"https://doi.org/10.1093/scan/nsag072","url":null,"abstract":"Patients with damage to the ventromedial prefrontal cortex (vmPFC) classically develop personality disturbances, emotion dysregulation, and social decision-making deficits that have been likened to psychopathic tendencies (\"pseudopsychopathy\"). These acquired deficits are thought to entail empathy impairments, viz., identifying other people's emotional experiences and caring about their well-being. However, these impairments may be due to either low motivation to empathize or impaired ability to empathize accurately. We examined whether patients with vmPFC lesions (who have been shown previously to have major deficits in empathy accuracy) would exhibit low empathy motivation. We conducted a lesion group comparison study to assess motivation to empathize. The results showed that damage to the vmPFC was not associated with low empathy motivation (including avoidance of affective or cognitive forms of empathy). Specifically, patients with vmPFC lesions did not avoid empathy any more so than comparison groups (participants with damage outside of the vmPFC or participants with no brain damage). Our findings suggest that patients with vmPFC damage may have preserved empathy motivation, at least in an off-line, laboratory task setting, despite their real-world impairments with deploying empathy. More research is needed to examine whether patients with vmPFC lesions would exhibit normal empathy motivation in everyday contexts.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148883218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pupil dilation reflects prediction errors in learning about others' personality traits. 瞳孔扩张反映了在了解他人性格特征时的预测错误。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-07-22 DOI: 10.1093/scan/nsag060

Sihui Zhang, Helen Blank, Ioannis Terzidis, Gabriela Rosenblau, Christoph W Korn

{"title":"Pupil dilation reflects prediction errors in learning about others' personality traits.","authors":"Sihui Zhang, Helen Blank, Ioannis Terzidis, Gabriela Rosenblau, Christoph W Korn","doi":"10.1093/scan/nsag060","DOIUrl":"https://doi.org/10.1093/scan/nsag060","url":null,"abstract":"Learning about others' personality traits is crucial for building personal relationships. This learning process can be conceptualized as reductions in prediction errors (PEs), defined as discrepancies between expectations about others and their subsequent feedback. While pupil dilation is a well-established marker of various learning processes, it remains less clear how it tracks the updating of estimations about others' personalities and reflects the dynamics of social learning. To test this, we conducted a pilot experiment and a preregistered main experiment where participants learned about either other people's trait profiles or a self-matched profile based on participant's own trait ratings. We hypothesized that pupil size would scale with PE magnitude during personality trait learning. Using linear mixed-effects models (LMMs), we confirmed that absolute PEs decreased over time in the main experiment, indicating successful learning. We then modeled pupillometry data to examine trial-by-trial relationships between absolute PEs and pupil dilation. In both experiments, larger absolute PEs were associated with larger pupil dilation, even after controlling for signed PEs and feedback. Furthermore, learning about self-matched profile yielded smaller PEs and correspondingly reduced pupil dilation. These findings suggest that pupil dilation tracks error magnitude and represents a critical physiological index of personality-trait learning about others.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148551952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RESTING-STATE NETWORKS IN SCHOOL-AGED VERY PRETERM CHILDREN: LINKS WITH COGNITION AND THEORY OF MIND. 学龄早产儿的静息状态网络：与认知和心智理论的联系。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-02-17 DOI: 10.1093/scan/nsag010

Marta Elena Carrasco-Solís, Sofia Amaoui, Carolina Laynez-Rubio, Ana Nieto-Ruiz, Aida Ruiz-López, Elisabeth Fernández-Marín, Ana Campos-Martínez, Manuel Molina-Oya, José Uberos-Fernández

{"title":"RESTING-STATE NETWORKS IN SCHOOL-AGED VERY PRETERM CHILDREN: LINKS WITH COGNITION AND THEORY OF MIND.","authors":"Marta Elena Carrasco-Solís, Sofia Amaoui, Carolina Laynez-Rubio, Ana Nieto-Ruiz, Aida Ruiz-López, Elisabeth Fernández-Marín, Ana Campos-Martínez, Manuel Molina-Oya, José Uberos-Fernández","doi":"10.1093/scan/nsag010","DOIUrl":"https://doi.org/10.1093/scan/nsag010","url":null,"abstract":"This study investigates the relationship between gestational age (GA) and resting-state functional connectivity (rsFC) in a cohort of very preterm children at school age, and how these neural patterns relate to cognitive and theory of mind (ToM) performance. Resting-state functional magnetic resonance imaging (fMRI) data were collected from 52 children (GA < 32 weeks, birth weight <1500 g) and independent component analysis was applied to extract the resting-state networks. Results showed that GA was positively associated with rsFC of the precuneus and the paracentral region within the left posterior cerebellar network (lpCER), while negatively associated with rsFC of the insula and putamen within the anterior default mode network (DMN), and with rsFC of the postcentral gyrus within the right frontoparietal network (rFPN). Cognitive and neuropsychological assessments revealed that increased connectivity involving the lpCER correlated with better verbal comprehension, visuospatial ability, fluid reasoning, working memory, and ToM performance. Conversely, increased aDMN connectivity was associated with lower working memory and decreased rFPN connectivity was found associated with lower intelligence quotient. These results underscore the influence of GA on intrinsic brain networks supporting cognitive and socio-cognitive functions, and highlight potential neural markers that could inform targeted intervention strategies for preterm children.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bidirectional coupling of physiology and emotions reveals unique speaker-listener dynamics. 生理和情绪的双向耦合揭示了独特的说者-听者动态。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-01-21 DOI: 10.1093/scan/nsag019

Mohanad Alkhodari, Ioannis Ziogas, Jace Singh, Paolo Grigolini, Glenn Muschert, Fedor Kusmartsev, Herbert F Jelinek

{"title":"Bidirectional coupling of physiology and emotions reveals unique speaker-listener dynamics.","authors":"Mohanad Alkhodari, Ioannis Ziogas, Jace Singh, Paolo Grigolini, Glenn Muschert, Fedor Kusmartsev, Herbert F Jelinek","doi":"10.1093/scan/nsag019","DOIUrl":"10.1093/scan/nsag019","url":null,"abstract":"Conversational interactions extend beyond verbal exchange, involving dynamic synchronization across physiological, emotional, and acoustic domains. This study aimed to characterize multimodal speaker-listener coupling during structured debates to examine how bidirectional dynamics relate to autonomic regulation, signal complexity, and emotional states. We analyzed data from the K-EmoCon database, which included 32 participants in 10-minute debates. Heart rate variability (HRV) features, speech features, and multi-perspective emotion annotations were synchronized and analyzed in segmented speak-listen phases. Cross-correlation and bidirectional coupling quantified coupling strength and directionality, and their relationships with emotional states were assessed. Negative lag segments showed significantly higher HRV features, including AVNN (0.655 [0.631-0.749], P = .003), HF power (0.620 [0.338-0.781], P < .001), and SD1 (1.30 × 10-3 [1.19-1.41] × 10-3, P = .003). Positive lag segments were associated with higher sample entropy (0.058 [0.046-0.065], P < .001) and diffusion entropy (μr: 1.209 [1.201-1.221], P < .001). Lower emotion states (1-2) tended to exhibit negative-lag dynamics, whereas moderate to high states (3 and 5) showed a modest positive-lag predominance. Multimodal coupling reveals distinct physiological and emotional signatures linked to leadership and responsiveness in conversation, providing insights for therapeutic, educational, and collaborative applications.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the role of executive function in brain responses to infant crying among new parents. 研究执行功能在新生儿哭闹时大脑反应中的作用。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-01-21 DOI: 10.1093/scan/nsag002

Daiki Hiraoka, Yun Xie, Shannon Powers, Genevieve Patterson, Jenna Chin, Nolan Brady, Tom Yeh, Pilyoung Kim

{"title":"Investigating the role of executive function in brain responses to infant crying among new parents.","authors":"Daiki Hiraoka, Yun Xie, Shannon Powers, Genevieve Patterson, Jenna Chin, Nolan Brady, Tom Yeh, Pilyoung Kim","doi":"10.1093/scan/nsag002","DOIUrl":"10.1093/scan/nsag002","url":null,"abstract":"Infant crying is a fundamental communication signal that captures caregiver attention and elicits caregiving responses. Executive function (EF) is critical in managing the cognitive and emotional demands of parenting, particularly in processing infant cues. This study explored the relationship between experienced EF difficulties and neural responses to infant crying among biological birthing parents. Participants were pregnant individuals from the Relationships of Parent-Infant Social, Emotional, and Brain Development project who completed the Behavior Rating Inventory of Executive Function-Adult Version during the third trimester. Postpartum, functional Magnetic Resonance Imaging measured brain activation in response to their own and other infants' cries, as well as control sounds. Greater experienced EF difficulties during pregnancy were prospectively associated with increased cry-evoked activation in lateral temporal regions, including a conjunction cluster in the left middle temporal gyrus shared across all four EF subdomains, and overlapping recruitment of regions such as the left superior temporal gyrus and right inferior frontal gyrus across multiple subdomains. These findings suggest that caregivers who report greater EF difficulties engage heightened auditory-temporal and control-related neural responses when processing infant distress signals, underscoring the relevance of EF-related individual differences for early parenting neurobiology.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12952922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146047526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensory encoding of emotion conveyed by the face and visual context. 通过面部和视觉环境传达的情感的感觉编码。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-01-21 DOI: 10.1093/scan/nsag028

Katherine M Soderberg, Grace Jang, Philip A Kragel

{"title":"Sensory encoding of emotion conveyed by the face and visual context.","authors":"Katherine M Soderberg, Grace Jang, Philip A Kragel","doi":"10.1093/scan/nsag028","DOIUrl":"10.1093/scan/nsag028","url":null,"abstract":"Humans rapidly detect and interpret sensory signals that have emotional meaning. The posterior superior temporal sulcus (pSTS) and amygdala are known to be critical for this ability, but their precise contributions remain contentious. Here we investigate how these structures process visual emotional cues using artificial neural networks (ANNs) to model fMRI signal acquired as human participants view complex, naturalistic stimuli. Characterizing data from two archival studies (Ns = 20, 45), we evaluated whether representations from ANNs optimized to recognize emotion from facial expressions alone or the broader visual scene differ in their ability to predict brain responses. We found that abstract representations of facial expressions were more strongly encoded in pSTS than the amygdala, whereas representations of the broader emotional scene were robustly encoded in both regions. These findings demonstrate how the pSTS operates on abstract representations of facial expressions to a greater extent than the amygdala, which more strongly encodes the broader emotional significance of visual information, depending on the context.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13235787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147966275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human brain network for reading the mind from the eyes: beyond activated and deactivated regions. 通过眼睛解读心灵的人脑网络：超越激活和失活区域。

IF 3.1

Social cognitive and affective neuroscience Pub Date : 2026-01-21 DOI: 10.1093/scan/nsag042

Maya Zheltyakova, Maxim Kireev, Artem Myznikov, Ruslan Masharipov, Mikhail Didur, Denis Cherednichenko, Alexander Korotkov

{"title":"Human brain network for reading the mind from the eyes: beyond activated and deactivated regions.","authors":"Maya Zheltyakova, Maxim Kireev, Artem Myznikov, Ruslan Masharipov, Mikhail Didur, Denis Cherednichenko, Alexander Korotkov","doi":"10.1093/scan/nsag042","DOIUrl":"10.1093/scan/nsag042","url":null,"abstract":"BOLD signal changes in the Theory of Mind (ToM) network often reflect reduced deactivation during target conditions, yet these below-baseline effects remain largely unaddressed. Using fMRI data from an extended version of the Reading the Mind in the Eyes Test, we examined task-modulated functional connectivity (TMFC) of these areas. We revealed that, despite below-baseline BOLD responses during the reading the mind in the eyes (RME) task, TPJ-pSTS subregions in the left middle and superior temporal gyri, and angular gyrus (AG) demonstrated TMFC patterns closely resembling those of ToM network areas in the pSTS and inferior frontal gyrus (IFG) showing above-baseline activations. The RME task-associated network included regions supporting affective mentalizing (bilateral TPJ-pSTS, IFG, middle frontal gyri, precentral gyri, supplementary motor area) and face-processing areas. These areas also elicited reduced TMFC with ToM network subregions in the AG, supramarginal gyrus, precuneus, and medial prefrontal cortex, associated with cognitive mentalizing. These findings demonstrate that regions with greater BOLD responses during the RME task, despite these responses remaining below baseline, are functionally engaged. Together, the results indicate a dynamic interaction between ToM network subcomponents during the RME task, characterized by engagement of the affective subcomponent and its functional segregation from the cognitive subcomponent.","PeriodicalId":94208,"journal":{"name":"Social cognitive and affective neuroscience","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13285000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0