Revista espanola de anestesiologia y reanimacion最新文献

筛选
英文 中文
National survey on perioperative cognitive dysfunction. 围手术期认知功能障碍全国调查。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-07-05 DOI: 10.1016/j.redare.2024.07.004
E M Aldana, N Pérez de Arriba, J L Valverde, C Aldecoa, N Fábregas, J L Fernández-Candil
{"title":"National survey on perioperative cognitive dysfunction.","authors":"E M Aldana, N Pérez de Arriba, J L Valverde, C Aldecoa, N Fábregas, J L Fernández-Candil","doi":"10.1016/j.redare.2024.07.004","DOIUrl":"10.1016/j.redare.2024.07.004","url":null,"abstract":"<p><strong>Background: </strong>Perioperative cognitive dysfunction (PCD) is a very prevalent clinical syndrome due to the progressive aging of the surgical population.The aim of our study is to evaluate the clinical practice of Spanish anesthesiologists surveyed regarding this entity.</p><p><strong>Material and methods: </strong>Prospective online survey conducted by the Neurosciences Section and distributed by SEDAR.</p><p><strong>Results: </strong>544 responses were obtained, with a participation rate of 17%. 54.4% of respondents never make a preoperative assessment of cognitive impairment, only 7.5% always do it. 79.6% lack an intraoperative management protocol for the patient at risk of PCD. In the anesthetic planning, only 23.3% of the patients was kept in mind. Eighty-nine percent considered regional anesthesia with or without sedation preferable to general anesthesia for the prevention of PCD. 88.8% considered benzodiazepines to present a high risk of PCD. 71.7% considered that anesthetic depth monitoring could prevent postoperative cognitive deficit. Routine evaluation of postoperative delirium is low, only 14%. More than 80% recognize that PCD is underdiagnosed.</p><p><strong>Conclusions: </strong>Among Spanish anesthesiologists surveyed, PCD is still a little known and underappreciated entity. It is necessary to raise awareness of the need to detect risk factors for PCD, as well as postoperative assessment and diagnosis. Therefore, the development of guidelines and protocols and the implementation of continuing education programs in which anesthesiologists should be key members of multidisciplinary teams in charge of perioperative care are suggested.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of intranasal dexmedetomidine and ketamine for paediatric premedication: A randomized study. 鼻内右美托咪定与氯胺酮用于儿科预处理的比较:随机研究。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-07-05 DOI: 10.1016/j.redare.2024.07.003
N Kumari, P K Dubey, S Singh
{"title":"Comparison of intranasal dexmedetomidine and ketamine for paediatric premedication: A randomized study.","authors":"N Kumari, P K Dubey, S Singh","doi":"10.1016/j.redare.2024.07.003","DOIUrl":"10.1016/j.redare.2024.07.003","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Paediatric patients are given premedication in order to decrease preoperative anxiety, allow smooth induction, and prevent postoperative psychological insult and behavioural changes. A child friendly method of administration is desirable. We compared intranasal administration of dexmedetomidine and ketamine in the operating room environment, to evaluate the Faces, Legs, Activity, Cry and Consolability (FLACC) score at the time of establishing intravenous access for induction of general anaesthesia.</p><p><strong>Methods: </strong>This prospective, double-blind, randomized controlled trial was conducted at a tertiary care center. One hundred patients, 2-10 years of age, ASA physical status 1 & 2, scheduled for general anaesthesia were enrolled. Patient's presedation behaviour was assessed by the modified Yale Preoperative Anxiety Scale Short Form (mYPAS-SF). Patients in Group D received Dexmedetomidine 1 mcg/kg intranasally, and patients in Group K received Ketamine 5 mg/kg intranasally. After 45 min, patients were transferred to the operating table where intravenous cannulation was carried out and the response to needle insertion was assessed by FLACC scale. Vital signs, including the pulse-oximetry, heart rate and respiratory rate were monitored. Side effects such as nausea, vomiting, and agitation were also recorded.</p><p><strong>Results: </strong>A significantly higher FLACC score was seen in Group D as compared to Group K (p = 0.001). The mean heart rate between two groups was found to be significantly (p = 0.001) lower in Group D compared to Group K. However, the proportion of adverse events was 8% in patients who received ketamine.</p><p><strong>Conclusions: </strong>Intranasal ketamine in a dose of 5 mg/kg is clinically more effective as premedication in children aged 2-10 years in comparison with intranasal dexmedetomidine in a dose of 1 mcg/kg.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pain in the pocket: Prevalence of pocket pain in patients with implantation of neuromodulation systems: A retrospective study. 口袋里的疼痛神经调控系统植入患者口袋疼痛的发生率:一项回顾性研究。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-07-05 DOI: 10.1016/j.redare.2024.07.002
J García Baos, Á Huete Marañés, Á Mingote, A Mendiola de la Osa, M Herrero Trujillano, C Ágreda García, S H Martínez Rodríguez, J García Fernández
{"title":"A pain in the pocket: Prevalence of pocket pain in patients with implantation of neuromodulation systems: A retrospective study.","authors":"J García Baos, Á Huete Marañés, Á Mingote, A Mendiola de la Osa, M Herrero Trujillano, C Ágreda García, S H Martínez Rodríguez, J García Fernández","doi":"10.1016/j.redare.2024.07.002","DOIUrl":"10.1016/j.redare.2024.07.002","url":null,"abstract":"<p><strong>Introduction: </strong>Implantable pulse generator (IPG) is a neurostimulation therapy mediated by electrodes and surgically implanted in a subcutaneous \"pocket\" used for the control of numerous pathologies. This study examines both the prevalence of pain associated with IPG implantation (\"pain pocket syndrome\") and its associated characteristics.</p><p><strong>Materials and methods: </strong>56 patients with an IPG were included in the study. A health questionnaire was conducted to determine the presence of pain associated with the pocket and its neuropathic characteristics, as well as associated aesthetic concerns, location, situations that accentuate or alleviate pain, medications used for baseline and pocket pain control and other factors associated.</p><p><strong>Results: </strong>Pain in the area of implantation of the IPG had a prevalence of 52.6% of patients (n = 27), in our sample, with a mean score on the visual analogic scale (VAS) of 4.9 points [3.9-5.8 points], with neuropathic characteristics in 53.3% (n = 16) of the patients with pain, with differences between the mean VAS score of the female (5.5 [4.3-5.8 points]) and males (3.5 points [2.1-4.9 points]) (p = 0.04).</p><p><strong>Conclusion: </strong>Pocket pain is a condition with a higher prevalence than described in previous studies, being of a higher intensity in females, involving a moderate pain in the area of implantation of the neuromodulating therapy. This pain has neuropathic characteristics and could require a repositioning intervention. Hence, more studies in this field should be carried to detect and prevent this syndrome.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategy for the management of acute postoperative pain in day surgery centres in Spain. DUCMA 2.0. project. 西班牙日间手术中心术后急性疼痛管理策略。DUCMA 2.0.项目。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-07-05 DOI: 10.1016/j.redare.2024.07.005
M Zaballos, A Reyes, J M Cordero, M Sánchez Hernández, L A Hidalgo, F Docobo Durantez, D Morales-Garcia
{"title":"Strategy for the management of acute postoperative pain in day surgery centres in Spain. DUCMA 2.0. project.","authors":"M Zaballos, A Reyes, J M Cordero, M Sánchez Hernández, L A Hidalgo, F Docobo Durantez, D Morales-Garcia","doi":"10.1016/j.redare.2024.07.005","DOIUrl":"10.1016/j.redare.2024.07.005","url":null,"abstract":"<p><strong>Introduction: </strong>Adequate treatment of acute postoperative pain is one of the quality requirements in ambulatory surgery and its suboptimal management is associated with delayed discharge, unplanned admissions and late admissions after home discharge. The aim of the present study was to learn about the organizational strategy for the management of postoperative pain in ambulatory surgery units (ASU) in Spain.</p><p><strong>Methods: </strong>A cross-sectional, multicenter study was carried out based on an electronic survey on aspects related to the management of acute postoperative pain in different ASUs in our country.</p><p><strong>Results: </strong>We recruited 133 ASUs of which 85 responded to the questions on the management of postoperative pain. Of the ASUs that responded, 80% had specific protocols for pain management and 37.6% provided preoperative information on the analgesic plan. The assessment of postoperative pain is carried out in 88.2% of the ASUs in the facility and only 56.5% at home. All ASUs use multimodal analgesia protocols; however, 68.2% report the use of opioids for the treatment of moderate to severe pain. Home invasive analgesia strategies are minimally used by the surveyed ASUs.</p><p><strong>Conclusions: </strong>The DUCMA study highlights that the practice of pain treatment in day surgery remains a challenge in our country and is not always in agreement with national guidelines. The results suggest the need to establish strategies to improve clinical practice and homogenize pain management in ambulatory surgery.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuous PENG block in an oncologic patient with bilateral femoral avascular necrosis 对一名双侧股骨头血管性坏死的肿瘤患者进行连续 PENG 阻滞。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2024.02.020
A. Server, V. Sánchez, E. Schmucker, Á. Mesas, J. Medel
{"title":"Continuous PENG block in an oncologic patient with bilateral femoral avascular necrosis","authors":"A. Server,&nbsp;V. Sánchez,&nbsp;E. Schmucker,&nbsp;Á. Mesas,&nbsp;J. Medel","doi":"10.1016/j.redare.2024.02.020","DOIUrl":"10.1016/j.redare.2024.02.020","url":null,"abstract":"<div><p>The PENG block (pericapsular nerve group) is a recently described technique to address the innervation of the hip, one of the most complex anatomical regions to treat at the locoregional level.</p><p>We present the case of a patient with acute lymphoblastic leukaemia complicated by avascular necrosis of the bilateral femoral head and previous history of severe chronic pain with probable central sensitization to opioids and a severe thrombocytopenia due to myelotoxicity from chemotherapy treatment.</p><p>Given the need for orthopaedic surgery to manage femoral necrosis and in anticipation of complex perioperative pain management, a multimodal strategy was planned including bilateral ultrasound-guided continuous PENG blocks to achieve proper pain control in the perioperative period and promote early recovery. The operation and initial recovery were uneventful and the patient was discharged to the ward within 24 h and started early rehabilitation as planned. The patient had a successful recovery with good functionality.</p></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of peri-surgical anemia in elective surgery. Conclusions and recommendations according to Delphi-UCLA methodology 择期手术围手术期贫血的管理。根据 Delphi-UCLA 方法得出的结论和建议
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2024.04.015
V. Moral , A. Abad Motos , C. Jericó , M.L. Antelo Caamaño , J. Ripollés Melchor , E. Bisbe Vives , J.A. García Erce , on behalf of the Expert Panel selected to carry out the Delphi Method
{"title":"Management of peri-surgical anemia in elective surgery. Conclusions and recommendations according to Delphi-UCLA methodology","authors":"V. Moral ,&nbsp;A. Abad Motos ,&nbsp;C. Jericó ,&nbsp;M.L. Antelo Caamaño ,&nbsp;J. Ripollés Melchor ,&nbsp;E. Bisbe Vives ,&nbsp;J.A. García Erce ,&nbsp;on behalf of the Expert Panel selected to carry out the Delphi Method","doi":"10.1016/j.redare.2024.04.015","DOIUrl":"10.1016/j.redare.2024.04.015","url":null,"abstract":"<div><h3>Introduction</h3><p>Preoperative anemia affects approximately one third of surgical patients. It increases the risk of blood transfusion and influences short- and medium-term functional outcomes, increases comorbidities, complications and costs. The “Patient Blood Management” (PBM) programs, for integrated and multidisciplinary management of patients, are considered as paradigms of quality care and have as one of the fundamental objectives to correct perioperative anemia. PBM has been incorporated into the schemes for intensified recovery of surgical patients: the recent Enhanced Recovery After Surgery 2021 pathway (in Spanish RICA 2021) includes almost 30 indirect recommendations for PBM.</p></div><div><h3>Objective</h3><p>To make a consensus document with RAND/UCLA Delphi methodology to increase the penetration and priority of the RICA 2021 recommendations on PBM in daily clinical practice.</p></div><div><h3>Material and Methods</h3><p>A coordinating group composed of 6 specialists from Hematology-Hemotherapy, Anesthesiology and Internal Medicine with expertise in anemia and PBM was formed. A survey was elaborated using Delphi RAND/UCLA methodology to reach a consensus on the key areas and priority professional actions to be developed at the present time to improve the management of perioperative anemia. The survey questions were extracted from the PBM recommendations contained in the RICA 2021 pathway. The development of the electronic survey (Google Platform) and the management of the responses was the responsibility of an expert in quality of care and clinical safety.</p><p>Participants were selected by invitation from speakers at AWGE-GIEMSA scientific meetings and national representatives of PBM-related working groups (Seville Document, SEDAR HTF section and RICA 2021 pathway participants).</p><p>In the first round of the survey, the anonymized online questionnaire had 28 questions: 20 of them were about PBM concepts included in ERAS guidelines (2 about general PBM organization, 10 on diagnosis and treatment of preoperative anemia, 3 on management of postoperative anemia, 5 on transfusion criteria) and 8 on pending aspects of research. Responses were organized according to a 10-point Likter scale (0: strongly disagree to 10: strongly agree). Any additional contributions that the participants considered appropriate were allowed. They were considered consensual because all the questions obtained an average score of more than 9 points, except one (question 14).</p><p>The second round of the survey consisted of 37 questions, resulting from the reformulation of the questions of the first round and the incorporation of the participants' comments. It consisted of 2 questions about general organization of PBM programme, 15 questions on the diagnosis and treatment of preoperative anemia; 3 on the management of postoperative anemia, 6 on transfusional criteria and finally 11 questions on aspects pending od future investigations.</p><p>Stati","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2341192924000830/pdfft?md5=287b1e57735d85b168f55ce092888864&pid=1-s2.0-S2341192924000830-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New logo of the “Societat Catalana d’Anestesiologia, Reanimació i Terapèutica del Dolor”, after 70 years of history 加泰罗尼亚麻醉、复苏和疼痛治疗协会 "在走过 70 年历程后的新徽标
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2024.04.016
X. Sala-Blanch , C. Morros , R. Adalia , M. Bausili
{"title":"New logo of the “Societat Catalana d’Anestesiologia, Reanimació i Terapèutica del Dolor”, after 70 years of history","authors":"X. Sala-Blanch ,&nbsp;C. Morros ,&nbsp;R. Adalia ,&nbsp;M. Bausili","doi":"10.1016/j.redare.2024.04.016","DOIUrl":"10.1016/j.redare.2024.04.016","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140775531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Before lumbar surgery is blamed for pneumocephalus, alternative causes must be thoroughly ruled out 在将气胸归咎于腰椎手术之前,必须彻底排除其他原因。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2024.02.026
J. Finsterer
{"title":"Before lumbar surgery is blamed for pneumocephalus, alternative causes must be thoroughly ruled out","authors":"J. Finsterer","doi":"10.1016/j.redare.2024.02.026","DOIUrl":"10.1016/j.redare.2024.02.026","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive extradural pneumorrhachis related to obstetric analgesia 与产科镇痛有关的硬膜外广泛性肺出血
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2023.09.009
M.J. Garcia-Cebrián , I.M. Fontan-Atalaya , J. Garcia-Perez , B. Fernandez-Torres
{"title":"Extensive extradural pneumorrhachis related to obstetric analgesia","authors":"M.J. Garcia-Cebrián ,&nbsp;I.M. Fontan-Atalaya ,&nbsp;J. Garcia-Perez ,&nbsp;B. Fernandez-Torres","doi":"10.1016/j.redare.2023.09.009","DOIUrl":"10.1016/j.redare.2023.09.009","url":null,"abstract":"<div><p>Iatrogenic extradural pneumorrhachis is a rare clinical entity, but anesthesiologists should be aware of this possibility when using the air technique for the identification of epidural space. Although in most published cases extradural pneumorrhachis is asymptomatic, relevant neurological consequences have been described, such as meningeal irritation, radicular pain, unilateral lower extremity weakness, cauda equina syndrome, paraplegia, and tetraplegia.We describe a very extensive extradural pneumorrachis (T9-S1), related to obstetric analgesia, in a patient with severe and atypical perineal pain after forceps-assisted delivery. Our aim is to synthesize and organize the available scientific evidence, analyzing preventive measures and summarizing the most appropriate diagnostic, follow-up and therapeutic techniques for symptomatic conditions, among which high concentrations of inspired oxygen, hyperbaric oxygen therapy and percutaneous or surgical decompression have been described.</p></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10587624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of coadministration of 10 mg/kg calcium chloride and neostigmine on extubation time: A randomized controlled trial 联合使用 10 毫克/千克氯化钙和新斯的明对拔管时间的影响:随机对照试验。
Revista espanola de anestesiologia y reanimacion Pub Date : 2024-06-01 DOI: 10.1016/j.redare.2024.04.004
S. Elkenany, M.M. Alseoudy, M.E. Elshehawi, S. Bakrey, M. Aboelela
{"title":"Effect of coadministration of 10 mg/kg calcium chloride and neostigmine on extubation time: A randomized controlled trial","authors":"S. Elkenany,&nbsp;M.M. Alseoudy,&nbsp;M.E. Elshehawi,&nbsp;S. Bakrey,&nbsp;M. Aboelela","doi":"10.1016/j.redare.2024.04.004","DOIUrl":"10.1016/j.redare.2024.04.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Some studies investigating the effect of calcium on neostigmine-induced recovery of neuromuscular blockade have shown that this combination promotes neuromuscular recovery, but does not significantly affect the incidence of postoperative residual curarization and time to extubation. This study aimed to evaluate the effects of 10 mg/kg calcium chloride co-administered with neostigmine on early recovery and time to extubation.</p></div><div><h3>Patients and methods</h3><p>This prospective, randomized, double-blinded, placebo-controlled study included 88 ASA I–II patients aged between 18 and 65 years who were scheduled for elective surgery lasting at least 1 h under general anaesthesia in which 10 mg/kg of calcium chloride or the same volume of normal saline was co-administered with 5 μg/kg of neostigmine at the end of surgery. Time to extubation (time from neostigmine administration to extubation), time from neostigmine administration to TOF ratio (TOFr) 0.9 (neuromuscular recovery), and the incidence of residual neuromuscular blockade (RNMB) and other adverse effects were recorded.</p></div><div><h3>Results</h3><p>Median (Q1, Q3) extubation time was significantly shorter in the calcium group vs. the placebo group (6.5 min [5.52–7.43] vs. 9.78 min [8.35–11]), <em>P</em> &lt; .001. Median neuromuscular recovery time in the calcium group was 5 min vs. 7.1 min in the placebo group, <em>P</em> &lt; .001. Patients in the calcium group had significantly higher TOFr and lower incidence of RNMB at 5 and 10 min vs. the placebo group, and no significant side effects.</p></div><div><h3>Conclusion</h3><p>Calcium chloride at a dose of 10 mg/kg co-administered with neostigmine promotes early neuromuscular recovery and reduces time to extubation by about 32%.</p></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信