Revista espanola de anestesiologia y reanimacion最新文献

{"title":"An adult case of acute encephalopathy associated with general anaesthesia and the m.11232T>C MT-ND4 variant.","authors":"I Arranz Chamorro, P Blanco-Schweizer, E Ruiz Pesini, M Busto Busto, T Ticona Espinoza, J Rodríguez Jiménez","doi":"10.1016/j.redare.2026.502103","DOIUrl":"10.1016/j.redare.2026.502103","url":null,"abstract":"<p><p>We report the case of a 20-year-old woman who developed acute encephalopathy after uneventful general anaesthesia with sevoflurane, propofol, and opioids. The patient presented neurological impairment followed by metabolic acidosis and hyperlactatemia and neuroimaging findings involving the basal ganglia, brainstem, and cerebellum. Genetic testing confirmed the mitochondrial variant m.11232T>C in the MT-ND4 gene, previously described only in paediatric patients. This case could be one of the first cases described in the literature of acute encephalopathy associated with this mutation in an adult patient, possibly precipitated by exposure to volatile anesthetics. The patient's favorable clinical and radiological evolution after intensive neuroprotective management and suboccipital decompressive craniectomy highlights the importance of early diagnosis and individualized treatment. Mitochondrial dysfunction should be considered in atypical neurological presentations following general anesthesia, especially when accompanied by lactic acidosis and unusual neuroimaging findings.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502103"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148883199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of RDW and lactate for short- and long-term mortality in critically ill patients with acute kidney injury.","authors":"A Guevara-Tirado","doi":"10.1016/j.redare.2026.502175","DOIUrl":"10.1016/j.redare.2026.502175","url":null,"abstract":"<p><strong>Introduction: </strong>In intensive care units, the strong association between acute kidney injury and mortality has led to a pressing need for simple biomarkers to improve prognostic stratification.</p><p><strong>Objective: </strong>To evaluate the prognostic value of RDW and lactate for short- and long-term mortality in critically ill patients with acute kidney injury.</p><p><strong>Materials and methods: </strong>An analytical study of an open dataset of 2,139 patients with acute kidney injury during their first ICU admission. The main biomarkers were RDW and lactate measured within the first 24 h, classified into 4 combined categories. Outcomes were 28-day, 90-day, and 1-year mortality. Multivariable logistic regression, Kaplan-Meier survival curves, and Cox adjusted proportional hazards models were used. Results were reported as odds ratios (OR) and hazard ratios (HR) with 95% confidence intervals.</p><p><strong>Results: </strong>Mortality increased across the combined RDW-lactate categories, with the highest rates observed in patients with both biomarkers elevated: 32.1% at 28 days, 43.6% at 90 days, and 53.0% at 1 year. In adjusted models, both RDW and lactate were independently associated with higher mortality. The RDW × lactate interaction was significant for 90-day mortality (OR 1.13). Cox analysis confirmed a higher risk of 90-day mortality in patients with both biomarkers elevated (HR 1.57). Kaplan-Meier curves showed significant differences in survival (log-rank p < 0.001).</p><p><strong>Conclusions: </strong>The combined evaluation of RDW and lactate may improve short- and long-term mortality risk stratification in critically ill patients with acute kidney injury.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502175"},"PeriodicalIF":0.0,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General anesthesia versus non-GA for endovascular thrombectomy of posterior circulation stroke: A five-year retrospective analysis of the impact on patient outcomes.","authors":"R P Sá, M B Antunes, R Torres, A T Cruz, A Marinho, T Meira, I Cerqueira","doi":"10.1016/j.redare.2026.502171","DOIUrl":"10.1016/j.redare.2026.502171","url":null,"abstract":"<p><strong>Introduction: </strong>The optimal anesthesia strategy during endovascular thrombectomy (EVT) for posterior circulation acute ischemic stroke (PC-AIS) remains unclear.</p><p><strong>Methods: </strong>We conducted a 5-year retrospective cohort study of consecutive PC-AIS patients treated with EVT and categorized by anesthetic modality: general anesthesia (GA) or non-GA. The primary outcome was functional independence at 90 days, defined as a modified Rankin Scale (mRS) score of 0-2. Secondary outcomes included successful reperfusion (mTICI 2b-3) and 3-month mortality. Multivariable logistic regression was used to adjust for confounding factors.</p><p><strong>Results: </strong>Of 132 patients, 55 (41.7%) underwent EVT under GA. Good functional outcome was achieved in 61.5% of GA patients versus 47.9% of non-GA patients. However, after adjustment, GA was not independently associated with functional independence (adjusted OR 0.72, 95% CI 0.22-2.31; p =  0.571). Reperfusion rates were similar for both groups (successful reperfusion: GA 84.1% vs. non-GA 81.7%, p =  0.458) and mortality at 3 months did not differ significantly (GA: 18.2% vs. non-GA: 20.8%; adjusted OR 2.41, 95% CI 0.78-7.47; p =  0.127).</p><p><strong>Discussion: </strong>There is no significant difference in outcomes between patients with PC-AIS undergoing EVT with GA versus non-GA. These findings align with recent evidence, suggesting comparable functional, angiographic, and survival outcomes across anesthetic strategies, though limitations related to retrospective design and practice variability remain.</p><p><strong>Conclusion: </strong>Anesthetic modality (GA vs. non-GA) does not significantly affect 3-month functional outcomes, successful reperfusion, or mortality during EVT for PC-AIS, supporting an individualized, patient- and procedure-based approach.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502171"},"PeriodicalIF":0.0,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondrial hypersensitivity to sevoflurane: Pharmacogenetics and the role of scientific societies.","authors":"Y Hernández-Castillo, E Ruiz-Pesini","doi":"10.1016/j.redare.2026.502197","DOIUrl":"10.1016/j.redare.2026.502197","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502197"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148835763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baskar® Mask versus ProSeal™ laryngeal mask airway for airway sealing and clinical performance in gynecologic laparoscopic surgery: A randomized trial.","authors":"M G Saad, N K Gaballa, H R Alkashgari, A Abodonya, A G Salah Elsawy, A M Abouelnasr Khalifa, S Abdalla Moursi, M Mostafa Elshamy, M Hegab, E F Ismail, A Deyab, R Elsafty, I Eltanani","doi":"10.1016/j.redare.2026.502196","DOIUrl":"10.1016/j.redare.2026.502196","url":null,"abstract":"<p><strong>Objective: </strong>To compare the oropharyngeal leak pressure and clinical performance of the Baska® mask and the ProSeal™ laryngeal mask airway (LMA) during controlled ventilation in gynecologic laparoscopic surgery.</p><p><strong>Methods: </strong>This prospective randomized controlled trial included 100 adult women with American Society of Anesthesiologists (ASA) physical status I-II undergoing elective gynecologic laparoscopic surgery. After induction of general anesthesia, patients were randomized to insertion of either the Baska mask (BM group, n = 50) or the ProSeal laryngeal mask airway (PL group, n = 50). The primary outcome was oropharyngeal leak pressure measured 10 min after establishment of pneumoperitoneum. Secondary outcomes included insertion time, ease of insertion, number of insertion attempts, intraoperative device displacement, and perioperative airway-related complications.</p><p><strong>Results: </strong>Oropharyngeal leak pressure was significantly higher in the BM group than in the PL group (median [IQR], 31 [28-33] vs 26 [25-28] cmH₂O; p < 0.001). Insertion time was significantly shorter with the Baska mask (9 [7-10] s vs 15 [13-16.8] s; p < 0.001). First-attempt success rates were comparable (96% vs 90%). Device displacement, blood-tinged sputum, and postoperative pharyngolaryngeal discomfort were not significantly different between groups. No patient required endotracheal intubation, and no episodes of vomiting occurred.</p><p><strong>Conclusion: </strong>In gynecologic laparoscopic surgery, the Baska mask provided higher oropharyngeal leak pressure and faster insertion than the ProSeal LMA, with a comparable perioperative safety profile.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502196"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148835642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of preoperative lactate concentration with in-hospital mortality after emergency surgery.","authors":"J Ripollés-Melchor, P Galán-Menéndez, Á V Espinosa, D Fernández-García, A Abad-Motos, R Navarro-Pérez, R Budithi, P Fernández-Valdes-Bango, A Abad-Gurumeta, C Aldecoa","doi":"10.1016/j.redare.2026.502208","DOIUrl":"10.1016/j.redare.2026.502208","url":null,"abstract":"<p><strong>Introduction: </strong>Lactate is widely used as a marker of metabolic and circulatory stress, but its prognostic value in emergency surgical populations remains incompletely defined.</p><p><strong>Methods: </strong>We performed a retrospective cohort study using the INSPIRE dataset, including emergency surgical procedures with a preoperative lactate measurement obtained within 6 h of incision. The primary outcome was in-hospital mortality. Multivariable logistic regression adjusted for age, sex, ASA physical status, surgical department, anaesthesia type, preoperative haemoglobin and creatinine. Lactate was analysed using restricted cubic splines and in prespecified categories (<2, 2-<4 and ≥4 mmol l^-¹). Incremental prognostic value was assessed by comparing a baseline clinical model with and without lactate.</p><p><strong>Results: </strong>The analytic cohort included 3729 emergency surgical procedures, of which 360 resulted in in-hospital death (9.7%). Mortality increased across lactate categories: 6.9% for lactate <2 mmol l^-¹, 13.9% for lactate 2-<4 mmol l^-¹ and 42.2% for lactate ≥4 mmol l^-¹. After adjustment, lactate was still associated with mortality (odds ratio 1.79 [95% CI 1.23-2.59] for 2-<4 mmol l^-¹ and 7.34 [4.65-11.57] for ≥4 mmol l^-¹ vs <2 mmol l^-¹). Adding lactate to the standard clinical model improved discrimination (AUC 0.755 vs 0.801) and reduced the Brier score (0.094 vs 0.088). Results were consistent across alternative measurement windows and after multiple imputation.</p><p><strong>Conclusion: </strong>Preoperative lactate concentration was strongly associated with in-hospital mortality and provided incremental prognostic information beyond routinely available variables. In emergency surgical pathways, lactate may support early risk stratification.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502208"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148835649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic changes in the internal jugular vein during supine and passive leg raising as predictors of spinal anesthesia-induced hypotension in the elderly: A prospective diagnostic accuracy study.","authors":"M Younes Taha, M A Helmy, E M Mostafa, O Asaad, N Sameh Fahmy, M Mohamed Mustafa","doi":"10.1016/j.redare.2026.502207","DOIUrl":"10.1016/j.redare.2026.502207","url":null,"abstract":"<p><strong>Background: </strong>Spinal anaesthesia-induced hypotension is common in elderly patients and is associated with serious complications, including myocardial ischaemia, arrhythmias, acute heart failure, stroke, kidney injury, and, in rare cases, perioperative blindness. Reliable predictors are needed to identify vulnerable patients before anaesthesia induction. This study evaluated whether dynamic changes in internal jugular vein diameter between supine and passive leg raising could predict spinal anaesthesia-induced hypotension in elderly patients.</p><p><strong>Methods: </strong>This prospective study was conducted at Cairo University Hospitals after ethics approval and trial registration. Patients older than 65 years, classified as American Society of Anesthesiologists physical status I-II, scheduled for elective infraumbilical surgery under spinal anaesthesia, were enrolled. Exclusion criteria included obesity, uncontrolled hypertension, reduced cardiac function, emergency surgery, and contraindication for spinal anaesthesia. Baseline haemodynamics were recorded supine. Internal jugular vein diameter and cross‑sectional area were measured by ultrasound in supine and passive leg raising positions. Spinal anaesthesia was performed with hyperbaric bupivacaine and fentanyl. Hypotension was defined as mean arterial pressure less than 65 mmHg or >20% lower than baseline. Receiver operating characteristic analysis was used to evaluate predictive accuracy.</p><p><strong>Results: </strong>Data from 70 of the 92 patients screened were included in the final analysis. Spinal anaesthesia-induced hypotension occurred in 42 patients (60%), with severe hypotension in 7 patients (10%). Patients who developed hypotension showed significantly greater reductions in mean arterial pressure compared with stable patients. Percentage changes in internal jugular vein diameter and cross‑sectional area between supine and passive leg raising were significantly higher in hypotensive patients (P < .001). Receiver operating characteristic analysis demonstrated excellent predictive accuracy: >11% change in diameter yielded an area under the curve of 1.00 with 100% sensitivity and specificity, while >21.5% change in cross‑sectional area achieved an area under the curve of 0.99 with 100% sensitivity and 93% specificity. Static measurements alone had poor predictive value.</p><p><strong>Conclusion: </strong>Dynamic changes in internal jugular vein diameter and cross‑sectional area during passive leg raising are reliable, noninvasive predictors of spinal anaesthesia-induced hypotension in elderly patients. Incorporating internal jugular vein ultrasonography into routine preoperative assessment may improve risk stratification and guide preventive strategies. Larger multicentre studies are needed to confirm these findings and evaluate their impact on clinical outcomes.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"502207"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148835817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can an antibiotic trigger a heart attack? Kounis syndrome induced by intraoperative amoxicillin allergy: a case report","authors":"M. Bernaola,&nbsp;A. Gago,&nbsp;A. Umpiérrez,&nbsp;López-Soberón,&nbsp;N.G. Kounis","doi":"10.1016/j.redare.2026.502035","DOIUrl":"10.1016/j.redare.2026.502035","url":null,"abstract":"<div><div>Kounis syndrome (KS) is an acute coronary syndrome triggered by mast cell degranulation in response to allergic or hypersensitivity reactions. Drug-induced KS, particularly due to antibiotics like amoxicillin, represents a severe and potentially life-threatening condition. This review aims to analyze the pathophysiology, clinical manifestations, diagnostic approaches, and management strategies of KS induced by amoxicillin allergy, with a focus on recent literature and emerging therapeutic insights.</div></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":"73 7","pages":"Article 502035"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146198331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of chronic post-surgical pain using the GENDOLCAT preoperative risk prediction model: Implementation in a university hospital","authors":"C. Morales Viveros,&nbsp;O. Comps Vicente,&nbsp;L. Moltó García,&nbsp;J.R. Castaño Asins,&nbsp;L. Aguilera Cuchillo,&nbsp;A. Montes Pérez","doi":"10.1016/j.redare.2026.502137","DOIUrl":"10.1016/j.redare.2026.502137","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic post-surgical pain (CPSP) affects 17% of patients undergoing surgery, and identifying those at risk is essential. In this analysis, we used the GENDOLCAT scale to evaluate the risk of CPSP (rCPSP) in patients scheduled for surgery and characterise those with rDCPQ ≥ 30%.</div></div><div><h3>Material and method</h3><div>We included patients scheduled for surgery in whom the rCPSP was calculated during the preoperative assessment using the GENDOLCAT scale, which includes the following variables: age, type of surgery, preoperative pain at the surgical site, preoperative pain in other areas of the body, and the physical and mental dimensions of the SF-12.</div></div><div><h3>Results</h3><div>We calculated the rCPSP of 589 patients who were divided into 4 groups according to the aggressiveness of their surgery. Four risk groups were defined: ≤10%; &gt;10%–20%; &gt;20%–30%; and ≥30%; the latter being high risk. A total of 22.8% (n = 134) had an rDCPQ ≥ 30%; the mean age was 48.9 ± 12.9; preoperative pain at the surgical site was 4.8 ± 3.5 (VNS) and 5.3 ± 2.9 (VNS) beyond the surgical site; the SF-12 physical and mental dimension scores were 34.7 ± 10.6 and 41.6 ± 12.4, respectively. Of this group, 34% (n = 46) underwent minimally aggressive procedures.</div></div><div><h3>Conclusions</h3><div>A high proportion of patients scheduled for surgery have a high risk of DCPQ, although many undergo minimally aggressive procedures. This shows the importance of using a systematic method to determine the risk of DCPQ in all surgical patients.</div></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":"73 7","pages":"Article 502137"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147960649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RICA pathway (Enhanced Recovery After Surgery for Adults). 2026 update: Executive summary","authors":"J.M. Ramírez-Rodríguez,&nbsp;P.M. Ruiz-López,&nbsp;J.M. Estrada-Lorenzo,&nbsp;A. Abad-Gurumeta,&nbsp;V. Bebia,&nbsp;R. Martín-Gil Parra,&nbsp;M.T. Fernández-Martín,&nbsp;B. Ugarte-Sierra,&nbsp;G. Bonaldo,&nbsp;M.J. Ocón-Bretón,&nbsp;I. Montllor-Ramoneda,&nbsp;N. Bouzó-Molina,&nbsp;A. Ribed-Sánchez,&nbsp;A. Giménez-Manzorro,&nbsp;J.A. García-Erce,&nbsp;D. Arnal-Velasco,&nbsp;H. Guadalajara-Labajo,&nbsp;J.V. Lorente-Olazábal,&nbsp;M.A. Gómez-Ríos,&nbsp;C. Ojeda-Thies,&nbsp;A. Arroyo-Sebastián","doi":"10.1016/j.redare.2026.502168","DOIUrl":"10.1016/j.redare.2026.502168","url":null,"abstract":"<div><div>The objective of the Continuous Update Project of the RICA Pathway (Enhanced Recovery After Surgery in Adults) is to maintain updated and consensual recommendations based on scientific evidence, facilitating their implementation and evaluation. The project was developed between November 2021 and October 2025, focusing on elective major surgery in adults. Evidence was evaluated using the GRADE methodology, with reviews in PubMed, Embase, and the Cochrane Library, including systematic reviews, meta-analyses, randomised clinical trials, consensus guidelines, and multicenter studies. The project was structured into a coordinating group, a consulting group, and various reviewing groups, and the recommendations were evaluated and accepted by consensus.</div><div>103 recommendations were approved, compared to 135 in the 2021 edition. 83% of these presented high or moderate evidence, and 76% had a strong grade of recommendation in favor. The recommendations were grouped into sets of measures (“bundles”) to improve their applicability.</div></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":"73 7","pages":"Article 502168"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148341677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}