Revista espanola de anestesiologia y reanimacion最新文献

{"title":"Predictors of response in patients with traumatic peripheral neuropathic pain treated with the 8% capsaicin patch.","authors":"L Monteagudo Moreno, P Cía Blasco, M Malo Urriés, A Nuez Polo, C Marín Zaldívar","doi":"10.1016/j.redare.2025.501880","DOIUrl":"10.1016/j.redare.2025.501880","url":null,"abstract":"<p><strong>Background and objectives: </strong>Neuropathic pain (NP) is a widespread, complex disorder that responds differently to pharmacological treatment. The aim of this study was to identify the baseline characteristics of good response to capsaicin 8% patch in patients with trauma-induced peripheral neuropathic pain (PNP).</p><p><strong>Materials and methods: </strong>We performed a prospective, longitudinal, open-label study in 31 patients with PNP treated with 1-3 applications of the capsaicin 8% patch for 52 weeks. Response to treatment was defined as a reduction in the Visual Analogue Scale (VAS) score compared to baseline. Data from responders and non-responders were compared at the start (month 1) and end (month 12) of treatment. Logistic regression was used to identify predictors of treatment response.</p><p><strong>Results: </strong>At month 1, responders (n = 17) had significantly larger treatment areas (155.18 cm² vs. 59.21 cm²; p = 0.004) and reported greater pain relief with treatments received in the previous week in the brief pain questionnaire (34.7% vs. 14.3%; p = 0.023). At month 12, significant predictors included cold allodynia (OR 8; p = 0.030), positive for painful cold in the DN4 questionnaire (OR 7.936; p = 0.019), no penetrating pain (OR 16.800; p = 0.009), and pain interference with work score <7.5 (OR 7.917; p = 0.019).</p><p><strong>Conclusions: </strong>This study makes a significant contribution to the management of post-traumatic peripheral neuropathic pain by providing tools to personalise treatment and optimize available resources.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501880"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of heart rate variability to assess functional capacity in multimodal rehabilitation programs in adult surgery: PreANI Study Protocol.","authors":"C Aragón-Benedí, S Ortega-Lucea, A Pascual-Bellosta, M Corcoy-Bidasolo, J Longas-Vailen, J Martinez-Ubieto","doi":"10.1016/j.redare.2025.501849","DOIUrl":"10.1016/j.redare.2025.501849","url":null,"abstract":"<p><strong>Background and objectives: </strong>Despite the implementation of multimodal rehabilitation programs, postoperative complications are common in some surgeries, and patient recovery is not as rapid as expected. This study was designed to evaluate whether postoperative outcomes can be improved by assessing preoperative functional reserve and frailty on the basis of heart rate variability, specifically Energy (SDNN) and the ANIm (HFnu) value, in patients following prehabilitation programs.</p><p><strong>Material and method: </strong>Prospective, observational cohort study that will include patients undergoing colorectal oncology surgery within a multimodal rehabilitation program. Patients will be monitored with the ANI device at 2 time points: initial (first pre-anaesthesia consultation, 4 weeks before surgery) and second consultation (1 week before surgery). Data will be collected on heart rate variability, energy, and ANIm values, cardiopulmonary exercise test scores, and other parameters.</p><p><strong>Results: </strong>We will analyse the correlation between heart rate variability indices and current functional assessment parameters, physiological reserve, and frailty (ASA scale, 6-minute walk test, MUST scale, and Clinical Frailty Scale). Our hypothesis is that higher energy levels (SDNN) will correlate with better postoperative outcomes, fewer complications, and shorter hospital stays.</p><p><strong>Conclusions: </strong>Statistical analysis will respect all principles of confidentiality and privacy. The results will be published in peer-reviewed journals. This study aims to provide a new tool for assessing frailty and functional reserve in surgical patients as a means of improving prehabilitation programs and postoperative outcomes.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501849"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway management in thoracic surgery in a patient with right tracheal supernumerary bronchus.","authors":"S Moreno-Jurico, M Roger, M Ubré, G Martínez-Pallí","doi":"10.1016/j.redare.2025.501771","DOIUrl":"10.1016/j.redare.2025.501771","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501771"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative management of patients on GLP-1 receptor agonist treatment: Risks and recommendations.","authors":"E Simón Polo, I Rubio Jiménez, N Aguirre Ahedo, M Sanjuán Fernández","doi":"10.1016/j.redare.2025.501859","DOIUrl":"10.1016/j.redare.2025.501859","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501859"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suzetrigine as a non-opioid analgesic: Between need and scientific evidence.","authors":"A Alcántara Montero","doi":"10.1016/j.redare.2025.501858","DOIUrl":"10.1016/j.redare.2025.501858","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501858"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of facial fillers on airway assessment.","authors":"C Juliá-Romero, B Simón-Rivero, L Ceresuela-Dionís, S de Benito-Mendieta","doi":"10.1016/j.redare.2025.501802","DOIUrl":"10.1016/j.redare.2025.501802","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501802"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the treatment of neuropathic pain from the Neuropathic Pain Special Interest Group of International Association for the Study of Pain.","authors":"A Alcántara Montero","doi":"10.1016/j.redare.2025.501856","DOIUrl":"10.1016/j.redare.2025.501856","url":null,"abstract":"","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501856"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the role of flow cytometry to assess endothelial cells in human sepsis: A systematic review.","authors":"M Bardají-Carrillo, M Martín-Fernández, A García-Concejo, Á Tamayo-Velasco, D Bernardo, E Tamayo","doi":"10.1016/j.redare.2025.501850","DOIUrl":"10.1016/j.redare.2025.501850","url":null,"abstract":"<p><strong>Introduction: </strong>Given the key role of the endothelium in organ failure secondary to sepsis, we reviewed the available literature on the use of flow cytometry (FC) to analyse endothelial cells in human sepsis.</p><p><strong>Methods: </strong>We systematically searched PubMed and Web of Science from inception until November 2024 to identify original research articles describing the use of FC to study human endothelial cells in sepsis.</p><p><strong>Results: </strong>A total of 395 original articles were found; 36 met the inclusion criteria. Ten studied circulating mature (CEC) or progenitor (CEPC) endothelial cells. High CEC and/or CEPC counts correlated with higher mortality; CEC numbers were increased even before the onset of shock. Twenty-six manuscripts studied the phenotype of different human microvascular endothelial cells (HMEC), and showed that expression of adhesion molecules ICAM-1, VCAM-1 and E-selectin were increased in sepsis, but there was no evidence of their association with severity or mortality.</p><p><strong>Conclusion: </strong>High CEC and CEPC counts correlate with sepsis severity and mortality, confirming that their assessment by FC can shed some light on early sepsis diagnosis.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501850"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative delirium in older adults: A retrospective cohort study.","authors":"J A Vélez-Restrepo, P A Betancourt-Ángel, J D Caicedo-Jaramillo, F D Casas-Arroyave","doi":"10.1016/j.redare.2025.501855","DOIUrl":"10.1016/j.redare.2025.501855","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Postoperative delirium (POD) is an adverse outcome that has garnered significant interest in perioperative medicine, particularly in older adults, due to its association with increased morbidity, mortality, and health care costs. In Colombia, this disease is under-reported due to the lack of POD diagnosis and prevention protocols. The aim of this study was to determine the incidence and potential risk factors of POD, and its association with other postoperative complications.</p><p><strong>Materials and methods: </strong>This retrospective cohort study was performed at a tertiary care hospital. Patients over 60 years of age who underwent surgery between 2012 and 2019 were included. Random sampling was used to analyse electronic medical records to estimate the incidence of POD, risk factors, and postoperative complications within 7 days of surgery.</p><p><strong>Results: </strong>A total of 2535 patients were evaluated. The cumulative incidence of POD was 6.0% (95% confidence interval [CI]: 5.1%-6.9%), with most cases (67%) occurring within the first 3 postoperative days. Risk factors associated with POD included a history of psychiatric disorders, preoperative opioid use, ASA (American Society of Anesthesiologists) class III/IV, vascular surgery, urgent or emergency surgery, and functional dependency. POD was also associated with higher in-hospital mortality (OR 2.9 [95% CI 1.66-5.07]).</p><p><strong>Conclusion: </strong>POD is common in patients aged over 60 undergoing surgery, particularly those that undergo urgent or emergency procedures and vascular surgery, who are ASA class > III, functionally dependent, and present psychiatric disorders. POD is also associated with increased postoperative morbidity and mortality.</p>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501855"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring of nociception by NoL Index and its implication in the reduction of opioid complications in laparoscopic abdominal surgery (SIMONE study): Protocol of a prospective, multicentre, observational cohort study","authors":"A.M. Pascual-Bellosta ,&nbsp;C. Aragón-Benedí ,&nbsp;S.M. Ortega-Lucea ,&nbsp;L. Mínguez-Braulio ,&nbsp;M. Buey-Aguilar ,&nbsp;A. Abad-Gurumeta ,&nbsp;E. Tamayo-Gómez ,&nbsp;J. Martinez-Ubieto ,&nbsp;SIMONE Trial Group","doi":"10.1016/j.redare.2025.501729","DOIUrl":"10.1016/j.redare.2025.501729","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Nociception monitoring allows for the titration of opioid drugs in the intraoperative period in order to avoid under- and overdosing of these drugs and their side effects in the patient’s postoperative period. For this reason, a study has been designed with the aim of establishing whether the usefulness of the NoL® (Nociception Level) device for adequate intraoperative nociception monitoring can reduce postoperative complications.</div></div><div><h3>Material and methods</h3><div>Multicentre, observational, prospective cohort study that will include patients who underwent laparoscopic abdominal surgery under balanced general anaesthesia during one year in different hospital centres in order to assess the incidence of early and late postoperative complications and their relationship with the monitoring of nociception studied through the NoL device. Intraoperative pain management will be based on NoL values (visible NoL group) or hemodynamic parameters according to usual clinical practice (non-visible NoL group).</div></div><div><h3>Results</h3><div>Approval has been obtained from the Autonomous Research Ethics Committee of Aragon (C.I. EPA23/026, 19 April 2023). Simone Studio was registered at <span><span>www.clinicaltrials.gov</span><svg><path></path></svg></span> on 30 May 2024 (Identifier: <span><span>NCT06437743</span><svg><path></path></svg></span>).</div></div><div><h3>Conclusions</h3><div>The overall data will be published in peer-reviewed journals. The relevance of the SIMONE study lies in being the first nationwide to comprehensively evaluate opioid dosing, postoperative pain, early and late postoperative complications, and the length of hospital stay. A significant reduction in the incidence of postoperative complications such as nausea and vomiting is expected in the group with visible NoL monitoring.</div></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":"72 6","pages":"Article 501729"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}