Canadian respiratory journal最新文献

{"title":"ILD-GAP Combined with the Charlson Comorbidity Index Score (ILD-GAPC) as a Prognostic Prediction Model in Patients with Interstitial Lung Disease.","authors":"Hiroaki Fujii,&nbsp;Yu Hara,&nbsp;Yusuke Saigusa,&nbsp;Yoichi Tagami,&nbsp;Kota Murohashi,&nbsp;Ryo Nagasawa,&nbsp;Ayako Aoki,&nbsp;Ami Izawa,&nbsp;Kenichi Seki,&nbsp;Keisuke Watanabe,&nbsp;Nobuyuki Horita,&nbsp;Nobuaki Kobayashi,&nbsp;Takeshi Kaneko","doi":"10.1155/2023/5088207","DOIUrl":"https://doi.org/10.1155/2023/5088207","url":null,"abstract":"<p><strong>Background: </strong>The ILD-GAP scoring system has been widely used to predict the prognosis of patients with interstitial lung disease (ILD). The ability of the ILD-GAP scoring system combined with the Charlson Comorbidity Index score (CCIS) (ILD-GAPC) to predict ILD prognosis was investigated.</p><p><strong>Methods: </strong>In ILD patients, including idiopathic pulmonary fibrosis (IPF), idiopathic nonspecific interstitial pneumonia (iNSIP), collagen vascular disease-related interstitial pneumonia (CVD-IP), chronic hypersensitivity pneumonitis (CHP), and unclassifiable ILD (UC-ILD), treated between April 2013 and April 2017, the relationships between baseline clinical parameters, including age, sex, CCIS, ILD diagnosis, pulmonary function test results, and disease outcomes, were retrospectively assessed, and the ability to predict prognosis was compared between the ILD-GAP and ILD-GAPC models, respectively.</p><p><strong>Results: </strong>A total of 185 patients (mean age, 71.9 years), all of whom underwent pulmonary function testing, including percentage predicted diffusion capacity for carbon monoxide, were assessed. ILD diagnosis consisted of IPF in 57 cases, iNSIP and CVD-IP in 117 cases, CHP in 6 cases, and UC-ILD in 5 cases. The ILD-GAPC provided a greater area under the receiver operating characteristic curve (0.758) for predicting 3-year ILD-related events than the ILD-GAP (0.721). In addition, log-rank tests showed that the Kaplan-Meier curves differed significantly among low, middle, and high ILD-GAPC scores (<i>P</i> < 0.001), unlike ILD-GAP scores (<i>P</i> = 0.083).</p><p><strong>Conclusions: </strong>The ILD-GAPC model could provide more accurate information for predicting prognosis in patients with ILD than the ILD-GAP model.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"5088207"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10828162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nocturnal Hypoventilation in the Patients Submitted to Thoracic Surgery.","authors":"Maciej Majchrzak,&nbsp;Cyryl Daroszewski,&nbsp;Piotr Błasiak,&nbsp;Adam Rzechonek,&nbsp;Paweł Piesiak,&nbsp;Monika Kosacka,&nbsp;Anna Brzecka","doi":"10.1155/2023/2162668","DOIUrl":"https://doi.org/10.1155/2023/2162668","url":null,"abstract":"<p><strong>Introduction: </strong>Nocturnal hypoventilation may occur due to obesity, concomitant chronic obstructive pulmonary disease (COPD), obstructive sleep apnea, and/or the use of narcotic analgesics. The aim of the study was to evaluate the risk and severity of nocturnal hypoventilation as assessed by transcutaneous continuous capnography in the patients submitted to thoracic surgery.</p><p><strong>Materials and methods: </strong>The material of the study consisted of 45 obese (BMI 34.8 ± 3.7 kg/m²) and 23 nonobese (25.5 ± 3.6 kg/m²) patients, who underwent thoracic surgery because of malignant (57 patients) and nonmalignant tumors. All the patients received routine analgesic treatment after surgery including intravenous morphine sulfate. Overnight transcutaneous measurements of CO₂ partial pressure (tcpCO₂) were performed before and after surgery in search of nocturnal hypoventilation, i.e., the periods lasting at least 10 minutes with tcpCO₂ above 55 mmHg.</p><p><strong>Results: </strong>Nocturnal hypoventilation during the first night after thoracic surgery was detected in 10 patients (15%), all obese, three of them with COPD, four with high suspicion of moderate-to-severe OSA syndrome, and one with chronic daytime hypercapnia. In the patients with nocturnal hypoventilation, the mean tcpCO₂ was 53.4 ± 6.1 mmHg, maximal tcpCO₂ was 59.9 ± 8.4 mmHg, and minimal tcpCO₂ was 46.4 ± 6.7 mmHg during the first night after surgery. In these patients, there were higher values of minimal, mean, and maximal tcpCO₂ in the preoperative period. Nocturnal hypoventilation in the postoperative period did not influence the duration of hospitalization. Among 12 patients with primary lung cancer who died during the first two years of observation, there were 11 patients without nocturnal hypoventilation in the early postoperative period.</p><p><strong>Conclusion: </strong>Nocturnal hypoventilation may occur in the patients after thoracic surgery, especially in obese patients with bronchial obstruction, obstructive sleep apnea, or chronic daytime hypercapnia, and does not influence the duration of hospitalization.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"2162668"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10058747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Flow Nasal Oxygen versus Noninvasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Randomized Controlled Trials.","authors":"Yanping Du,&nbsp;Huaping Zhang,&nbsp;Zhiyi Ma,&nbsp;Jun Liu,&nbsp;Zhiyong Wang,&nbsp;Meixia Lin,&nbsp;Fayu Ni,&nbsp;Xi Li,&nbsp;Hui Tan,&nbsp;Shifan Tan,&nbsp;Yanling Chai,&nbsp;Xiangzhu Zhong","doi":"10.1155/2023/7707010","DOIUrl":"https://doi.org/10.1155/2023/7707010","url":null,"abstract":"<p><strong>Background: </strong>High-flow nasal cannula (HFNC) can be used in stable chronic obstructive pulmonary disease (COPD) patients, but the effect of HFNC on clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is still uncertain.</p><p><strong>Methods: </strong>We searched electronic literature databases for randomized controlled trials (RCTs) comparing HFNC with noninvasive ventilation (NIV) in hypercapnic patients with AECOPD. The primary endpoint of this meta-analysis was PaCO₂, PaO_2, and SpO₂. The secondary outcomes were the respiratory rate, mortality, complications, and intubation rate.</p><p><strong>Results: </strong>We included 7 RCTs with a total of 481 patients. There were no significant differences on measures of PaCO₂ (MD = -0.42, 95%CI -3.60 to 2.75, <i>Z</i> = 0.26, and <i>P</i> = 0.79), PaO₂ (MD = -1.36, 95%CI -4.69 to 1.97, <i>Z</i> = 0.80, and <i>P</i> = 0.42), and SpO₂ (MD = -0.78, 95%CI -1.67 to 0.11, <i>Z</i> = 1.72, <i>P</i> = 0.08) between the HFNC group and the NIV group. There was no significant difference in measures of the mortality and intubation rate between the HFNC group (OR = 0.72, 95%CI 0.30 to 1.69, <i>Z</i> = 0.76, and <i>P</i> = 0.44) and the NIV group (OR = 2.38, 95%CI 0.49 to 11.50, <i>Z</i> = 1.08, and <i>P</i> = 0.28), respectively. But the respiratory rate in the HFNC group was lower than that in the NIV group (MD = -1.13, 95%CI -2.13 to -0.14, <i>Z</i> = 2.23, and <i>P</i> = 0.03), and fewer complications were found in the HFNC group (OR = 0.26, 95%CI 0.14 to 0.47, <i>Z</i> = 4.46, and <i>P</i> < 0.00001).</p><p><strong>Conclusion: </strong>NIV was noninferior to HFNC in decreasing PaCO₂ and increasing PaO₂ and SpO₂. Similarly, the mortality and intubation rate was similar among the two groups. The respiratory rate and complications were inferior in the AECOPD group treated with HFNC.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"7707010"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10187499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Risk Factors of 30-Day Death in Traumatic Lower Limb Fracture Patients with Acute Pulmonary Embolism: A Single-Center Retrospective Study.","authors":"Huanhuan Li,&nbsp;Yijun Yu,&nbsp;Yuting Wang,&nbsp;Qian Zhang,&nbsp;Ye Gu","doi":"10.1155/2023/8246730","DOIUrl":"https://doi.org/10.1155/2023/8246730","url":null,"abstract":"<p><strong>Background: </strong>To explore the prognostic risk factors of 30-day death in patients with traumatic lower limb fracture (TLLF) complicated with acute pulmonary embolism (APE).</p><p><strong>Methods: </strong>295 consecutive TLLF patients diagnosed as APE according to pulmonary artery CT angiography, hospitalized in our hospital from January 2017 to December 2021, were included in this study. Patients were divided into nonsurvival group and survival group according to 30-day follow-up results. After adjusting age, sex, and all the clinical variables with <i>P</i> values of <0.2 with backward stepwise method (likelihood ratio), multivariate Cox regression analysis was used to analyze risk factors of 30 days all-cause death in TLLF patients with APE. The area under curve (AUC) calculated by receiver operating characteristic curve (ROC) and the incremental model were used to determine the prognostic potential of identified risk factors.</p><p><strong>Results: </strong>29 patients died during 30-day follow-up. Simplified pulmonary embolism severity index (sPESI) score ≥1 (<i>P</i> < 0.05), Wells score ≥7 (<i>P</i> < 0.01), and pulmonary hypertension (<i>P</i> < 0.01) were associated with higher risk, while anticoagulant therapy (<i>P</i> < 0.01) was associated with lower risk of all-cause death during 30 days follow-up in APE patients. Compared with sPESI score, Wells score plus pulmonary hypertension produced better predictive efficacy. Prognostic value of sPESI score could be enhanced by adding Wells score, pulmonary hypertension, and anticoagulant therapy to the predicting models.</p><p><strong>Conclusions: </strong>Wells score ≥7 and pulmonary hypertension are independent predictive risk factors of 30-day all-cause death in TLLF patients with APE.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"8246730"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9932828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Factors of Nonmalignant Pathological Diagnosis and Final Diagnosis of Ultrasound-Guided Cutting Biopsy for Peripheral Pulmonary Diseases.","authors":"Qing Li,&nbsp;Li Zhang,&nbsp;Xinhong Liao,&nbsp;Yanfen Zhong,&nbsp;Zhixian Li","doi":"10.1155/2023/5815755","DOIUrl":"https://doi.org/10.1155/2023/5815755","url":null,"abstract":"<p><p>This study aimed to explore the predictive factors of nonmalignant pathological diagnosis and final diagnosis of ultrasound-guided cutting biopsy for peripheral pulmonary diseases. A total of 470 patients with peripheral lung disease diagnosed as nonmalignant by ultrasound-guided cutting biopsy in the First Affiliated Hospital of Guangxi Medical University from January 2017 to May 2020 were included. Ultrasound biopsy was performed to determine the correctness of pathological diagnosis. Independent risk factors of malignant tumor were predicted by multivariate logistic regression analysis. Pathological biopsy results showed that 162 (34.47%) of the 470 biopsy data were specifically benign, and 308 (65.53%; malignant lesions: 25.3%, benign lesions: 74.7%) were nondiagnostic findings. The final diagnoses were benign in 387 cases and malignant in 83 cases. In the nondiagnostic biopsy malignant risk prediction analysis, lesion size (OR = 1.025, <i>P</i> = 0.005), partial solid lesions (OR = 2.321, <i>P</i> = 0.035), insufficiency (OR = 6.837, <i>P</i> < 0.001), and presence of typical cells (OR = 34.421, <i>P</i> = 0.001) are the final important independent risk factors for malignant tumors. In addition, 30.1% (25/83) of patients with nonmalignant lesions who were finally diagnosed with malignant tumors underwent repeated biopsy, and 92.0% (23/25) were diagnosed during the second repeated biopsy. 59.0% (49/83) received additional invasive examination. Nondiagnostic biopsy predictors of malignant risk include lesion size, partial solid lesions, insufficiency, and presence of atypical cells. When a nonmalignant result is obtained for the first time, the size of the lesion, whether the lesion is subsolid, and the type of pathology obtained should be reviewed.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"5815755"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9660376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Bilirubin Levels and Disease Severity in Patients with Pneumoconiosis.","authors":"You-Fan Peng,&nbsp;Jun-Hua Deng,&nbsp;Xiao-Ying Huang,&nbsp;Qing-Song Zhang","doi":"10.1155/2023/5642040","DOIUrl":"https://doi.org/10.1155/2023/5642040","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the association between serum bilirubin and disease severity in patients with pneumoconiosis.</p><p><strong>Methods: </strong>The study comprised 45 patients with pneumoconiosis retrospectively; all pneumoconiosis patients were classified into I, II, and III stage according to the radiological severity.</p><p><strong>Results: </strong>Serum direct bilirubin levels were significantly lower in III stage pneumoconiosis patients than those in I/II stage (<i>p</i> = 0.012) but not serum indirect bilirubin. Serum direct bilirubin was negatively correlated with radiological severity in patients with pneumoconiosis (<i>r</i> = -0.320; <i>p</i> = 0.032); by multiple linear-regression analysis, we observed that serum direct bilirubin levels had independent association with radiological severity in patients with pneumoconiosis (beta = -0.459; <i>p</i> = 0.005).</p><p><strong>Conclusions: </strong>Serum direct bilirubin levels are negatively associated with disease severity in patients with pneumoconiosis.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"5642040"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9187406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MCP-4 and Eotaxin-3 Are Novel Biomarkers for Chronic Obstructive Pulmonary Disease.","authors":"Chun Fang,&nbsp;Baoguo Kang,&nbsp;Pan Zhao,&nbsp;Jing Ran,&nbsp;Lifang Wang,&nbsp;Lingqiong Zhao,&nbsp;Hangyu Luo,&nbsp;Ling Tao","doi":"10.1155/2023/8659293","DOIUrl":"https://doi.org/10.1155/2023/8659293","url":null,"abstract":"<p><p>The aim of our study was to examine the production of monocyte chemoattractant protein (MCP-4) and eotaxin-3 during the onset and progression of COPD. The expression levels of MCP-4 and eotaxin-3 were evaluated in COPD samples and healthy controls using immunostaining and ELISA. The relationship between the clinic pathological features in the participants and the expression of MCP-4 and eotaxin-3 were evaluated. The association of MCP-4/eotaxin-3 production in COPD patients was also determined. The results revealed enhanced production of MCP-4 and eotaxin-3 in COPD patients especially the cases with AECOPD in both bronchial biopsies and bronchial washing fluid samples. Furthermore, the expression signatures of MCP-4/eotaxin-3 show high AUC values in distinguishing COPD patients and healthy volunteers and AECOPD and stable COPD cases, respectively. Additionally, the number of MCP-4/eotaxin-3 positive cases was notably increased in AECOPD patients compared to those with stable COPD. Moreover, the expression of MCP-4 and eotaxin-3 was positively correlated in COPD and AECOPD cases. In addition, the levels of MCP-4 and eotaxin-3 could be increased in HBEs stimulated with LPS, which is a risk factor of COPD. Moreover, MCP-4 and eotaxin-3 may exert their regulatory functions in COPD by regulating CCR2, 3, and 5. These data indicated that MCP-4 and eotaxin-3 were potential markers for the clinical course of COPD, which could provide guidance for accurate diagnosis and treatment for this disease in future clinical practice.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"8659293"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9580628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between CT Score and KL-6: A Severity Assessing in Juvenile Dermatomyositis Associated Interstitial Lung Disease.","authors":"Chi Wang,&nbsp;Jun Hou,&nbsp;Jianming Lai,&nbsp;Ran Tao,&nbsp;Yang Yang,&nbsp;Wenhan Hao,&nbsp;Xinyu Yuan,&nbsp;Yuchun Yan","doi":"10.1155/2023/5607473","DOIUrl":"https://doi.org/10.1155/2023/5607473","url":null,"abstract":"<p><strong>Background: </strong>There is no radiological measurement to estimate the severity of pediatrics juvenile dermatomyositis (JDM) with interstitial lung disease (ILD). We validated the effectiveness of CT scoring assessment in JDM patients with ILD.</p><p><strong>Aim: </strong>To establish a CT scoring system and calculate CT scores in JDM patients with ILD and to determine its reliability and the correlation with Krebs von den Lungen-6 (KL-6).</p><p><strong>Methods: </strong>The study totally enrolled 46 JDM-ILD patients and 16 JDM without ILD (non-ILD, NILD) patients. The chest CT images (7.0 ± 3.6 years; 32 male and 30 female) were all analyzed. CT scores of six lung zones were retrospectively calculated, included image pattern score and distribution range score. Image pattern score was defined as follows: increased broncho-vascular bundle (1 point); ground glass opacity (GGO) (2 points); consolidation (3 points); GGO with bronchiectasis (4 points); consolidation with bronchiectasis (5 points); and honeycomb lung (6 points). Distribution range score was defined as no infiltrate (0 point); <30% (1 point); 30%-60% (2 points); and ≥60% (3 points). Two pediatric radiologists reviewed all CT images independently. The ROC curve was established, and the optimal cutoff score for severity discrimination was set.</p><p><strong>Results: </strong>The agreement between two observers was excellent, and the ICC was 0.930 (95% CI 0.882-0.959, <i>p</i> < 0.01). CT score and KL-6 level had a positive linear correlation (<i>r</i> = 0.784, <i>p</i> < 0.01). However, the correlation between CT scores of different lung zone and KL-6 level was different. The KL-6 cut off level suggested for JDM with ILD was 209.0 U/ml, with 73.9% sensitivity and 87.5% specificity, and the area under curve was (AUC) 0.864 (<i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>The CT scoring system we established, as a semiquantitative method, can effectively evaluate ILD in JDM-PM patients and provide reliable evidence for treatment.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"5607473"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9618881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Risk Factors of Needle Thoracentesis Decompression in Tension Pneumothorax in Patients over 75 Years Old.","authors":"Yanhu Wang,&nbsp;Lei Wang,&nbsp;Cheng Chen,&nbsp;Yifan Que,&nbsp;Yinyi Li,&nbsp;Jiang Luo,&nbsp;Ming Yin,&nbsp;Miao Lv,&nbsp;Guogang Xu","doi":"10.1155/2023/2602988","DOIUrl":"https://doi.org/10.1155/2023/2602988","url":null,"abstract":"<p><strong>Background: </strong>There are very few professional recommendations or guidelines on the needle thoracentesis decompression (NTD) for the tension pneumothorax in the elderly. This study aimed to investigate the safety and risk factors of tension pneumothorax NTD in patients over 75 years old based on CT evaluation of the chest wall thickness (CWT).</p><p><strong>Methods: </strong>The retrospective study was conducted among 136 in-patients over 75 years old. The CWT and closest depth to vital structure of the second intercostal space at the midclavicular line (second ICS-MCL) and the fifth intercostal space at the midaxillary line (fifth ICS-MAL) were compared as well as the expected failure rates and the incidence of severe complications of different needles. We also analyzed the influence of age, sex, presence or absence of chronic obstructive pulmonary disease (COPD), and body mass index (BMI) on CWT.</p><p><strong>Results: </strong>The CWT of the second ICS-MCL was smaller than the fifth ICS-MAL both on the left and the right side (<i>P</i> < 0.05). The success rate associated with a 7 cm needle was significantly higher than a 5 cm needle (<i>P</i> < 0.05), and the incidence of severe complications with a 7 cm needle was significantly less than an 8 cm needle (<i>P</i> < 0.05). The CWT of the second ICS-MCL was significantly correlated with age, sex, presence or absence of COPD, and BMI (<i>P</i> < 0.05), whereas the CWT of the fifth ICS-MAL was significantly correlated with sex and BMI (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The second ICS-MCL was recommended as the primary thoracentesis site and a 7 cm needle was advised as preferred needle length for the older patients. Factors such as age, sex, presence or absence of COPD, and BMI should be considered when choosing the appropriate needle length.</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"2602988"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection\".","authors":"Wei Dai,&nbsp;Xinmiao Chen,&nbsp;Xiaoting Xu,&nbsp;Zhefeng Leng,&nbsp;Wenwen Yu,&nbsp;Hui Lin,&nbsp;Huiying Li,&nbsp;Jie Lin,&nbsp;Zhangwei Qiu,&nbsp;Yuanrong Dai","doi":"10.1155/2023/9784697","DOIUrl":"https://doi.org/10.1155/2023/9784697","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2020/2045341.].</p>","PeriodicalId":9416,"journal":{"name":"Canadian respiratory journal","volume":"2023 ","pages":"9784697"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}