Nuklearmedizin. Nuclear medicine最新文献

{"title":"Successful PRRT-rechallenge in a metastasized neuroendocrine tumor of the middle ear.","authors":"Juri Ruf, Christoph Becker, Philippe Dovi-Akué, Volker Brass, Steffen Heeg","doi":"10.1055/a-1856-4290","DOIUrl":"https://doi.org/10.1055/a-1856-4290","url":null,"abstract":"","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"416-417"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40621260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The Youngsters of the German Society of Nuclear Medicine (Young DGN)].","authors":"Adrien Holzgreve, Friederike Eilsberger, Eric Einspänner, Johannes Kunz, Yasemin Aylin Sahin, Sarah Spreckelmeyer, Markus Luster, Constantin Lapa, Michael Schäfers, Benjamin Kläsner, Young Dgn","doi":"10.1055/a-1866-3000","DOIUrl":"https://doi.org/10.1055/a-1866-3000","url":null,"abstract":"Institute 1 Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany 2 Department of Nuclear Medicine, University Hospital of Giessen and Marburg, Campus Marburg, Marburg, Germany 3 Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Otto von Guericke University, Magdeburg, Germany 4 Nuclear Medicine, MVZ Radiologie Nuklearmedizin, Bethanien-Krankenhaus, Frankfurt am Main, Germany 5 Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany 6 Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nuclear Medicine, Berlin, Germany 7 Nuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany 8 Department of Nuclear Medicine, University Hospital Münster, Münster, Germany 9 Department of Nuclear Medicine, Klinikum Konstanz, Konstanz, Germany","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"290-292"},"PeriodicalIF":1.5,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40493633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audiovisual intervention alleviates anxiety of patients during PET/CT imaging.","authors":"Safae Abouzian,&nbsp;Valle Camacho,&nbsp;Aida Sabaté,&nbsp;Patricia Stefaneli,&nbsp;Marina Sizova,&nbsp;Ignasi Gich,&nbsp;Diego López-Mora,&nbsp;Joan Duch,&nbsp;Alejandro Fernández,&nbsp;Montserrat Estorch,&nbsp;Ignasi Carrió,&nbsp;Albert Flotats","doi":"10.1055/a-1759-4062","DOIUrl":"https://doi.org/10.1055/a-1759-4062","url":null,"abstract":"<p><strong>Aim: </strong>to assess if the use of an audiovisual intervention in the uptake room and/or in the scanning room, could help to reduce anxiety during [18F]FDG PET/CT imaging.</p><p><strong>Methods: </strong>We prospectively studied 120 patients referred for [18F]FDG PET/CT imaging. Patients were allocated in 4 groups of 30 patients depending on the use of the audiovisual intervention: (1) no audiovisual intervention; (2) audiovisual intervention only in the uptake room; (3) audiovisual intervention only in the scanning room; (4) audiovisual intervention in the uptake and the scanning rooms. In order to measure the anxiety levels of the patients before and after the scan, all patients answered the State-Trait Anxiety Inventory (STAI).</p><p><strong>Results: </strong>The anxiety status across typical situations on a daily basis (STAI-T) of the 4 groups of patients was comparable with no significant differences. The mean State Anxiety (STAI-S) sum-score at prescan and postscan among groups was: (1) 17.5±8.7 vs. 17.3±8.6, p=0.834; (2) 17.4±10.5 vs. 15.8±9.6, p=0.110; (3) 17.5±11.7 vs. 15.1±9.8, p= 0.013; (4) 17.4±9.7 vs. 14.9±8.1, p= 0.009. The percentage of patients with reduction of the STAI-S score among groups 1-4 was 17%, 47%, 50%, and 66%, respectively. The variation of the percentage of patients with lower scores after intervention among groups was statistically significant (p<0.001).</p><p><strong>Conclusion: </strong>Audiovisual intervention decreases anxiety levels of patients referred for PET/CT imaging. The results of our study support a beneficial effect of the audiovisual intervention and its potential to alleviate the anxiety of oncological patients who undergo a PET/CT scan.</p>","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"301-307"},"PeriodicalIF":1.5,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40587785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparison of 186Re to 662 keV photon radiation concerning biological radiation effect on the human B-cell line BV-173].","authors":"Jennifer Staudt,&nbsp;Christian Happel,&nbsp;Wolfgang Tilman Kranert,&nbsp;Benjamin Bockisch,&nbsp;Frank Grünwald","doi":"10.1055/a-1560-2079","DOIUrl":"https://doi.org/10.1055/a-1560-2079","url":null,"abstract":"<p><p>ZIEL: Ziel der Untersuchung ist es, die Strahlenwirkung des β^--Emitters ¹⁸⁶Re und von 662keV-Photonenstrahlung zu ermitteln, um die biologische Wirkung von Strahlung niedriger Dosisleistung (¹⁸⁶Re) mit der hoher Dosisleistung zu vergleichen.</p><p><strong>Material und methoden: </strong>Zellen der humanen Leukämie-Zelllinie BV-173 wurden mit 662keV-Photonenstrahlung respektive ¹⁸⁶Re bestrahlt. In einem Inkubationszeitraum von 7 Tagen wurden Zahl und Vitalität der Zellen täglich bestimmt und als Dosiseffektkurven basierend auf der Vitalität dargestellt. Hierfür wurde der Zeitpunkt mit minimalem Überleben verwendet (72h ¹⁸⁶Re und 24h Photonenstrahlung).</p><p><strong>Ergebnisse: </strong>Beide Strahlenarten zeigen am Auswertezeitpunkt (72h nach Versuchsbeginn für ¹⁸⁶Re und 24h nach Versuchsbeginn für Photonenstrahlung) eine Überlebenskurve mit biexponentiellem Verlauf. Für Photonenstrahlung ist dies erklärbar durch eine Hypersensitivität im niedrigen Dosisbereich bis 1Gy, für die sich eine D₀ von 3,3Gy ergibt, für Dosen über 1,0Gy liegt die D₀ bei 10Gy. Für die ¹⁸⁶Re-Inkubation ergibt sich eine D₀ von 11,1Gy bei niedrigen Dosen verursacht durch die Reparatur subletaler Schäden, durch welche die biologische Wirkung abgeschwächt wird. Ab einer akkumulierten Dosis von etwa 1,6Gy zeichnet sich für ¹⁸⁶Re ein wesentlich steilerer Kurvenverlauf mit einer D₀ von 4,0Gy ab, der eine in diesem Bereich 2,5-fach stärkere biologische Wirkung als akute Photonenstrahlung wiedergibt (D₀ 4Gy für ¹⁸⁶Re bzw. 10Gy für Photonen).</p><p><strong>Schlussfolgerung: </strong>Strahlung niedriger Dosisleistung zeigt eine geringere biologische Wirkung als eine akute Bestrahlung. Es existiert aber ein Grenzwert der akkumulierten Dosis, ab dem die biologische Wirkung von β-Strahlung die der Photonenstrahlung sogar übertrifft.</p>","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"438-444"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39330371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early response evaluation using 18F-FDG-PET/CT does not influence management of patients with metastatic gastrointestinal stromal tumors (GIST) treated with palliative intent.","authors":"Sheima Farag,&nbsp;Nikki S IJzerman,&nbsp;Matthijs P M Houdijk,&nbsp;An K L Reyners,&nbsp;Anne Ij Arens,&nbsp;Dirk J Grünhagen,&nbsp;Ingrid M E Desar,&nbsp;Hans Gelderblom,&nbsp;Neeltje Steeghs,&nbsp;Lioe-Fee de Geus-Oei","doi":"10.1055/a-1542-6211","DOIUrl":"https://doi.org/10.1055/a-1542-6211","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to investigate the impact of ¹⁸F-FDG-PET/CT on treatment decision making in metastatic gastrointestinal stromal tumor (GIST) patients.</p><p><strong>Methods: </strong>This study retrospectively evaluated ¹⁸F-FDG-PET/CT scans to monitor response of metastatic GIST patients treated with palliative intent. Data from the Dutch GIST Registry was used. Early scans (<10 weeks after start of treatment) and late scans (>10 weeks after start of treatment) were scored on the impact in change of treatment.</p><p><strong>Results: </strong>Sixty-one PET/CT scans were performed for treatment evaluation in 39 patients with metastatic GIST of which 36 were early scans and 25 were late scans. Early PET/CT scans led to a change in management in 5.6% of patients and late PET/CT scans led to a change in management in 56% of patients. Change in management was more often seen after scans with lack of metabolic response (48% vs. 11% in scans with metabolic response, p=0.002). Neither metabolic response nor change in treatment were more often seen in patients with <i>KIT</i> mutations compared to patients with non-<i>KIT</i> mutations (metabolic response 65% <i>KIT</i> vs. 46% non-<i>KIT</i>, p=0.33, and change in management 28% <i>KIT</i> vs. 21% non-<i>KIT</i>, p=0.74).</p><p><strong>Conclusion: </strong>¹⁸F-FDG-PET/CT is not recommended for early response evaluation in an unselected patient population with metastatic GIST, since it does not influence treatment decisions. ¹⁸F-FDG-PET/CT, however, can be useful for late response assessment, especially in case of indeterminate CT results.</p>","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"411-416"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39381821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities.","authors":"Lara Franziska Stolzenbach, Florian Löcherbach, Katharina Wargenau, Randi Pose, Thomas Steuber, Zhe Tian, Lars Budäus, Derya Tilki, Markus Graefen, Daniel Köhler, Pierre I Karakiewicz, Markus Sauer, Ivayla Ilieva Apostolova, Tobias Maurer, Christoph Berliner","doi":"10.1055/a-1542-6064","DOIUrl":"10.1055/a-1542-6064","url":null,"abstract":"<p><strong>Aim: </strong>Few small-scaled studies performed systematic analysis of the benefits of extending prostate specific membrane antigen positron-emission tomography/ computed tomography (⁶⁸Ga-PSMA I&T PET/CT) to the lower extremities in prostate cancer (PCa) patients. We hypothesized that ⁶⁸Ga-PSMA I&T PET/CT positive lesions are rare in lower extremities of prostate cancer (PCa) patients, the clinical implication is negligible and may therefore be omitted.</p><p><strong>Methods: </strong>We retrospectively analyzed 1,068 PCa patients who received ⁶⁸Ga-PSMA I&T PET/CT in a single institution (2016-2018). Of those, 285 (26.7%) were newly diagnosed, 529 (49.5%) had biochemical recurrence (BCR) and 254 (23.8%) were castration-resistant prostate cancer (CRPC) patients.</p><p><strong>Results: </strong>Of 1,068 ⁶⁸Ga-PSMA I&T PET/CTs, positive lesions in the lower extremities were identified in 6.9% patients (n=74). Positive lesions in the lower extremities were most common in CRPC patients (19.7%; n=50), followed by newly diagnosed (3.2%; n=9) and BCR (2.8%; n=15) PCa patients. Only 3 patients presented with exclusive lesions in the lower extremities, respectively 0.8% (n=2) in CRPC and 0.4% (n=1) in newly diagnosed PCa. Both CRPC (94.1%, n=47) and BCR (80.0%, n=12) patients with PSMA-positive lesions predominantly received systemic therapy.</p><p><strong>Conclusion: </strong>Identification of lower extremities lesions with PSMA PET/CT is uncommon and exclusive lesions are rare. PSMA PET/CT findings of the lower extremities did not change therapy management. Thus, scanning of the lower extremities can be omitted in standard protocols.</p>","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"417-424"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39330372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thymic squamous cell carcinoma mimicking lymphoma on 68Ga-FAPI PET/CT.","authors":"Xiao Yang,&nbsp;Zhouxiang You,&nbsp;Yue Chen,&nbsp;Tianyang Dai,&nbsp;Huipan Liu","doi":"10.1055/a-1561-2014","DOIUrl":"https://doi.org/10.1055/a-1561-2014","url":null,"abstract":"A 33-year-old man presented with progressive enlargement of supraclavicular fossa mass for 2 years. Recently, the patient feels neck pain when swallowing food. Previous chest CT imaging revealed an anterior mediastinal soft tissue mass without any evidence for adjacent vascular or lung invasion (approximately 4.1 cm × 3.4 cm in size), indicating a mediastinal tumor; therefore, malignancy could not be ruled out. With the consent of the patient, we enrolled him in a clinical trial of 68Ga-FAPI-04 PET/CT in tumors (ChiCTR2100044131). 68Ga-FAPI-04 PET/CT scan (▶ Fig. 1A-D) detected that the anterior mediastinal mass had intense FAPI uptake (SUVmax of 12.0). Based on these PET/CT findings, the lesion was suspected to be a mediastinal lymphoma. Subsequently, the patient underwent surgical resection of soft tissue mass. Immunohistochemistry revealed CK (+), CK19 (+), P63 (+), CD1a (+), TdT (+), CD5 (+), CD20 (+), CD117 (+), P53 (+, 50 %), Ki-67 (+, 40 %). However, the findings were consistent with thymic squamous cell carcinoma (SCC). Finally, the patient was well at the six-month follow-up visit.","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"454-455"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39320903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FDG uptake in axillary lymph nodes after COVID-19 vaccination - a pitfall in a case of highly suspicious lymph node metastases of malignant melanoma.","authors":"Clemens Mingels,&nbsp;Ian Alberts,&nbsp;Claudia Fischlin,&nbsp;Jan Wartenberg,&nbsp;Ali Afshar-Oromieh,&nbsp;Axel Rominger","doi":"10.1055/a-1561-2046","DOIUrl":"https://doi.org/10.1055/a-1561-2046","url":null,"abstract":"","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"456-457"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39326914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Analysis of Multimodal Skeletal SPECT/CT Reconstructions in Diagnosing Medication-related Osteonecrosis of the Jaw.","authors":"Michael Thomas Beck,&nbsp;Gregor Rugel,&nbsp;Julia Reinfelder,&nbsp;Torsten Kuwert,&nbsp;Philipp Ritt,&nbsp;Sebastian Kreissel,&nbsp;Tilo Schlittenbauer","doi":"10.1055/a-1525-7621","DOIUrl":"https://doi.org/10.1055/a-1525-7621","url":null,"abstract":"<p><strong>Aim: </strong>Our goal was to assess visual and quantitative aspects of multimodal skeletal SPECT/CT reconstructions (recon) in differentiating necrotic and healthy bone of patients with suspected MRONJ.</p><p><strong>Methods: </strong>Prior to surgery, 20 patients with suspected MRONJ underwent SPECT/CT of the jaw 3-4 hours after injection of Tc-99m-DPD (622±112.4 MBq). SPECT/CT data were reconstructed using the multimodal xSPECT Bone and xSPECT Quant algorithms as well as the OSEM-algorithm FLASH 3D. For analysis, we divided the jaw into 12 separate regions. Both xSPECT Bone and FLASH 3D datasets were scored on a four-point scale (VIS xSPECT; VIS F3D), based on the intensity of localized tracer uptake. In F3D and xSPECT Quant datasets, local tracer uptake of each region was recorded as semi-quantitative uptake ratio (SQR F3D) or SUVs, respectively. ROC analysis was performed. Postoperative histologic results served as gold standard.</p><p><strong>Results: </strong>VIS F3D, VIS xSPECT and SQR F3D did not differ significantly in diagnostic accuracy (VIS xSPECT sensitivity=0.64; specificity=0.89). Of the quantitative parameters, SUVpeak yielded the best interobserver reproducibility. SUVpeak was 9.9±7.1 (95%CI: 7.84-11.95) in MRONJ regions, as opposed 3.6±1.8 (95% CI:3.36-3.88) elsewhere, with a cutpoint of 4.5 (sensitivity=0.83; specificity=0.80). Absolute quantitation significantly surpassed VIS and SQR (p<0.05) in accuracy and interobserver agreement (SUVpeak: κ=0.92; VIS xSPECT: κ=0.61; SQR F3D κ=0.66).</p><p><strong>Conclusion: </strong>Absolute quantitation proved significantly more accurate than visual and semi-quantitative assessment in diagnosing MRONJ, with higher interobserver agreement.</p>","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"403-410"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39301735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Oldies (but Goldies): Peritoneal Scintigraphy in Chronic Peritoneal Dialysis Patients].","authors":"Christoph Berliner,&nbsp;Kristina Boss,&nbsp;Anke Pape,&nbsp;Andreas Kribben,&nbsp;Wolfgang Fendler,&nbsp;Ken Herrmann","doi":"10.1055/a-1542-6247","DOIUrl":"https://doi.org/10.1055/a-1542-6247","url":null,"abstract":"Die Peritonealhöhle wird von der größten und komplexesten serösen Haut des Menschen, dem Peritoneum, ausgekleidet. Das Peritoneum ermöglicht die Mobilität der intestinalen Strukturen und spielt eine Rolle beim intraabdominellen Flüssigkeitsaustausch. In diesem Zusammenhang wird das Peritoneum medizinisch auch für Dialyse eingesetzt [1]. Die Peritonealdialyse ist ein elegantes und relativ komplikationsarmes Verfahren, welches sich die hohe Permeabilität des Peritoneums zunutze macht. Nichtsdestotrotz treten auch bei diesem Verfahren Komplikationen auf, welche mit der Peritonealszintigrafie weiter abgeklärt werden können. Klassische Indikation ist die Evaluation einer pleuroperitonealen, skrotalen oder extraperitonealen Leckage [2, 3]. Ebenso können Katheterdysfunktionen durch Adhäsionen oder Obstruktionen mittels Peritonealszintigrafie abgeklärt werden [4]. Die Peritonealszintigrafie ist ein funktionelles Verfahren zur Darstellung der Peritonealhöhle mittels Einbringens einer geringen Menge radioaktiv markierten Tracers über einen intraperitoneal einliegenden Zugang/Katheter. Abgesehen von der geringeren räumlichen Auflösung hat die Szintigrafie als dynamisches Verfahren viele Vorteile gegenüber alternativen Techniken wie CT, MRT oder Sonografie. In der Kombination mit einer SPECT/CT ist auch die 3-dimensionale Zuordnung Artefakt-frei möglich. Zur Durchführung wird ein Zugang zur Peritonealhöhle benötigt. Idealerweise wird der einliegende Peritonealdialysekatheter (PD-Katheter) verwendet. Adaptiert an die Fragestellung werden 120–300MBq 99mTc-Human Serumalbumin (HSA) zusammen mit der Peritonealdialyselösung injiziert. Initial erfolgt eine dynamische Aufnahme alle 10 Sekunden über 5 Minuten zur Beurteilung von Katheterleckagen oder einer Fehllage in der Bauchwand. Anschließend erfolgen statische Aufnahmen nach 10 Minuten und einer Stunde. Bei Auffälligkeiten oder zum Abschluss der Untersuchung sollte eine SPECT/CT erfolgen. Je nach Fragestellung werden Spätaufnahmen nach 24 oder 48 Stunden ergänzt (▶ Tab. 1). Nachfolgend präsentieren wir 4 Peritonealdialysepatienten, die im Zeitraum von August 2020 bis März 2021 untersucht worden sind.","PeriodicalId":94161,"journal":{"name":"Nuklearmedizin. Nuclear medicine","volume":" ","pages":"450-453"},"PeriodicalIF":1.5,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39345673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}