Neuro endocrinology letters最新文献_第3页

Gingiva as immunological protection of the periodontium. Minireview. 牙龈作为牙周的免疫保护。微型访谈。

Neuro endocrinology letters Pub Date : 2024-11-28

Michal Straka, Matej Straka

{"title":"Gingiva as immunological protection of the periodontium. Minireview.","authors":"Michal Straka, Matej Straka","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: The anti-infective, predominantly antibacterial protection of the periodontium has been well-mapped in its various inflammatory diseases, especially in different clinical forms of gingivitis and periodontitis. In various inflammatory periodontal diseases, many immunocompetent cells and substances have been identified in periodontal structures, including the gingiva, which implement and ensure this anti-inflammatory response. There is ample evidence that in many clinical forms of gingivitis and periodontitis, these immunological-defensive reactions occur in the gingival tissue. Our small review study aims to demonstrate that gingival tissue acts as a small immunological-defensive organ localized in the tissue of healthy gingiva at the necks of the teeth throughout the lifetime of our patients. Furthermore, through a literature search, we investigated whether the anti-inflammatory and defensive equipment and responses are identical in differently inflamed and clinically healthy gingiva.Material and methods: We compiled a small review study that illuminates the knowledge on the gingiva as an immunocompetent organ through a focused search and retrieval of currently available literature sources. Our small review study aims to demonstrate that gingival tissue acts as a small defensive-immunological organ localized in the healthy gingival tissue at the dental necks throughout the lifetime of our patients. Furthermore, through a literature search, we investigated whether the anti-inflammatory and defensive equipment and responses are identical in differently inflamed and clinically healthy gingiva.Conclusion: Our findings confirm ongoing anti-inflammatory, immunological, and regenerative responses and processes in healthy gingival tissue that prevent bacterial and viral microorganisms from crossing into deeper periodontal tissues. From these results, we can further conclude that the healthy human gingiva performs an essential function as a relatively independent and small anti-inflammatory and lymphatic organ.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 5","pages":"321-324"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A woman with multifocal lipodystrophy in unilateral trunk and extremities. 女性单侧躯干及四肢多灶性脂肪营养不良。

Neuro endocrinology letters Pub Date : 2024-11-28

Haiyan Zi, Ailan Pang, Ting Pu, Xiaoguang Lei

引用次数: 0

Neurological symptoms and complications of influenza in the elderly. 老年人流感的神经系统症状和并发症。

Neuro endocrinology letters Pub Date : 2024-11-28

Robin Šín, Miroslav Kubiska

{"title":"Neurological symptoms and complications of influenza in the elderly.","authors":"Robin Šín, Miroslav Kubiska","doi":"","DOIUrl":"","url":null,"abstract":"Background: An in-depth study of neurological symptoms and complications of influenza in elderly patients. This population group is more susceptible to complications of the disease and these complications are more likely to end in death.Methods: A retrospective analysis of patient data was performed. All patients aged 65 years and older were included in the study. The study period was from the 1st of January , 2018 to 31st of December, 2021. All symptoms and complications of influenza were analyzed. Especially neurological and general symptoms were analyzed. Data were extracted from the complete medical records of the patients.Results: The most common symptoms of influenza in the elderly were fever in 218 cases (83.52%), cough in 189 patients (72.41%), general weakness in 182 (69.73%) and fatigue in 166 patients (63.6%). Myalgias were experienced by 106 patients (40.61%) and arthralgias by 101 patients (38.7%). Headache occurred in only 21 patients (8.06%). Encephalopathy was observed in 7 elderly patients (2.68%) during hospitalization. Influenza encephalitis was noted in 2 cases.Conclusion: The most common neurological symptoms of influenza in more than half of the elderly are general weakness and increased fatigue. Myalgias are common, headache less often. Nausea is not uncommon. Of the complications, encephalopathy is the most common. Cases of influenza encephalitis have also been reported. We have not encountered a stroke. Concerning other complications, bacterial pneumonia was the most common.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 5","pages":"309-314"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary cortisol/DHEA ratio response to acute academic stress and its association with performance in middle-to-late adolescents. 中后期青少年对急性学习压力的唾液皮质醇/DHEA比率反应及其与学习成绩的关系。

Neuro endocrinology letters Pub Date : 2024-11-04

Jorge A Barrero, Felipe Duarte-Zambrano, Luz Helena Aranzález, Marcela Cruz-González, Ismena Mockus

{"title":"Salivary cortisol/DHEA ratio response to acute academic stress and its association with performance in middle-to-late adolescents.","authors":"Jorge A Barrero, Felipe Duarte-Zambrano, Luz Helena Aranzález, Marcela Cruz-González, Ismena Mockus","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: Neuroendocrine coupling across adolescent transition conditions a stage of heightened variability in hypothalamic-pituitary-adrenal axis stress reactivity, likely impacting the adaptive physiological response to psychological stressors during adolescence. This study aimed to assess the salivary cortisol, DHEA, and cortisol/DHEA ratio variation in response to acute academic stress and its association with academic performance.Methods: A longitudinal observational study with a combined event- and time-based protocol was conducted. Twenty-two middle-to-late adolescents (mean age 17.6 ± 0.3 years) performed a 60-minute written examination in which saliva samples for cortisol and DHEA determination were collected at four points: before the examination and after its completion, and at the same time points on a control day. Academic performance was assessed based on the examination score determined by the number of marks awarded for each correct response.Results: Salivary cortisol (p = 0.012) and cortisol/DHEA ratio (p = 0.004) were significantly higher at pre-examination. When compared to students with low academic performance, high-achieving students exhibited higher cortisol levels (p = 0.026) and a higher cortisol/DHEA ratio (p = 0.017) at post-examination. Bivariate analysis showed a moderate positive correlation between academic performance and the post-examination cortisol/DHEA ratio (rs(20) = 0.44, p = 0.039), which significantly predicted academic performance (F(1,20) = 4.63, β = 0.09, CI 95% [0.003, 0.171], p = 0.044).Conclusion: In middle-to-late adolescents, the salivary cortisol/DHEA ratio response to acute academic stress is positively associated with academic performance. The findings of this study provide evidence of the neuroendocrine response to a cognitive demanding stressor as an adaptive mechanism likely mediated by the effect of an acute cortisol surge in cognition enhancement.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 4","pages":"255-261"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Practical viewpoints on ethical questions and dilemmas in schema therapy. 关于模式疗法中的伦理问题和困境的实用观点。

Neuro endocrinology letters Pub Date : 2024-11-04

Jan Prasko, Marie Ociskova, Ilona Krone, Julija Gecaite-Stonciene, Marija Abeltina, Roman Liska, Milos Slepecky, Alicja Juskiene

{"title":"Practical viewpoints on ethical questions and dilemmas in schema therapy.","authors":"Jan Prasko, Marie Ociskova, Ilona Krone, Julija Gecaite-Stonciene, Marija Abeltina, Roman Liska, Milos Slepecky, Alicja Juskiene","doi":"","DOIUrl":"","url":null,"abstract":"Background: Ethics is an inherent part of psychotherapy that protects the interests and rights of all parties engaged in the therapeutic relationship. This article focuses on ethical issues and dilemmas that may arise when using schema therapy.Method: We created a narrative review by searching the databases PubMed, Web of Science, and Scopus with the keywords \"psychotherapy\", \"schema therapy\", \"therapeutic relationship\", \"ethics\", \"ethical questions\", and \"ethical dilemmas\". In addition, we focused on the clinical experience of therapists, training instructors, and supervisors.Results: Ethical psychotherapy requires adherence to ethical codes and standards. Among the most important ethical principles are confidentiality, informed consent, boundaries of the therapeutic relationship, and dual relationships. Understanding transference, countertransference, and one's modes and schemas is essential to ethical reflection in schema therapy. The article presents examples of ethical dilemmas in schema therapy and suggests possible solutions. At the same time, we point out the need for further research in this field.Conclusion: Similarly to other psychotherapeutic approaches, one of the schema therapist's core competencies is following the profession's ethical principles and productively finding solutions to the occasional ethical dilemmas. Ethics is a prominent part of all psychotherapeutic sessions. Still, it becomes even more central when working with challenging issues such as personality disorders that schema therapy routinely treats. More research on the topic is needed.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 4","pages":"294-306"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review of relationship obsessive-compulsive disorder: Characteristics, causes and cognitive-behavioural interventions.. 关系强迫症的叙述性回顾：特征、原因和认知行为干预措施.

Neuro endocrinology letters Pub Date : 2024-11-04

Jan Prasko, Marie Ociskova, Ilona Krone, Julius Burkauskas, Julija Gecaite-Stonciene, Frantisek Hodny, Marija Abeltina, Milos Slepecky

{"title":"A narrative review of relationship obsessive-compulsive disorder: Characteristics, causes and cognitive-behavioural interventions..","authors":"Jan Prasko, Marie Ociskova, Ilona Krone, Julius Burkauskas, Julija Gecaite-Stonciene, Frantisek Hodny, Marija Abeltina, Milos Slepecky","doi":"","DOIUrl":"","url":null,"abstract":"Aim: The paper describes the characteristics of relationship obsessive-compulsive disorder (R-OCD), including the types of obsessions and compulsions, the common triggers and the impact on psychological well-being and relationship functioning. It also offers basic cognitive-behavioural strategies to help patients change their attitudes towards obsessive thoughts and reduce compulsive behaviours.Methods: This article is a narrative review of the literature and case studies on R-OCD. To search for relevant sources, we used PubMed, PsycINFO and Web of Science databases with the keywords \"relationship obsessive compulsive disorder\", \"R-OCD\", \"relationship OCD\" and \"partner-focused OCD\". We included only studies published in English from January 1990 to June 2023. The paper provides examples of how basic cognitive-behavioural strategies help individuals with R-OCD.Results: People with R-OCD experience intrusive thoughts about whether they have the right feelings for their partner, whether their partner loves them, whether the relationship is suitable or whether their partner has flaws. These thoughts trigger the urge to perform various rituals to alleviate anxiety, such as repeated checking, reassurance or comparison. However, this behaviour leads to disruption of the relationship and long-term maintenance of the anxiety. Examples of basic cognitive-behavioural strategies can be applied in clinical practice to help individuals change their attitudes towards relational obsessive thoughts and reduce compulsive behaviours.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 4","pages":"262-280"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aggressive behaviour in mentally altered patients in prehospital setting as a threat to emergency medical service personnel: potential predictors identification. 院前环境中精神失常患者的攻击行为对急救人员的威胁：潜在预测因素识别。

Neuro endocrinology letters Pub Date : 2024-11-04

Lukáš Handl, Robin Šín, Tomáš Nagy

{"title":"Aggressive behaviour in mentally altered patients in prehospital setting as a threat to emergency medical service personnel: potential predictors identification.","authors":"Lukáš Handl, Robin Šín, Tomáš Nagy","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: Patients are the most common source of violence against EMS personnel. This study aims at elucidating specific clinical features in patients with mental alteration and aggressive behaviour increasing risk of violence.Material and methods: This consecutive cross-sectional retrospective study analysed consecutive patients treated for prespecified list of primary diagnoses by one EMS provider in the Czech Republic between 1 January 2021 and 31 December 2023. The effect of individual features of medical history and present symptoms on the occurrence of violence, need for the Police assistance and use of restraints was evaluated, using linear regression model.Results: 410 patients were evaluated. Verbal and brachial violence was present in 21.5 and 12.9 %, respectively. Police assistance was needed in 48.3 %, restraints were used in 4.6 %. The most significant predictor for violence, need for Police or restraints was agitation (OR 7.02, CI 4.14 - 11.90; OR 2.60, CI 1.60 - 4.24, OR 11.02, CI 3.49 - 34.80 respectively). Other predictors of violence included history of acute psychotic attacks and psychotic disorders, or outpatient psychiatry care. Among other predictors for Police assistance was presence of delusions, paranoia and history of outpatient psychiatry care.Conclusion: Prehospital care for patients with mental status alteration and aggressive behaviour is complex. Some clinical features seem to increase the risk of violence. Future research in the evaluation of agitated and violent patients is warranted to find strategies of risk mitigation for EMS personnel.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 4","pages":"239-249"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between salivary melatonin and interoceptive awareness. 唾液褪黑激素与感知间意识之间的关系

Neuro endocrinology letters Pub Date : 2024-11-04

Misa Kurihara, Hideki Ohira

引用次数: 0

Hydrogen sulfide improved learning and memory deficits by reversing the inhibition of methylmercuric chloride on BDNF/TrkB signaling pathway. 硫化氢可逆转甲基氯化物对 BDNF/TrkB 信号通路的抑制，从而改善学习和记忆缺陷。

Neuro endocrinology letters Pub Date : 2024-11-04

Xiumei Cheng, Xinyi Cao, Yichun Yang, Lingxiao Wang, Yuxuan Yang, Yunjian Pan, Yongliang Zheng, Churong Wei, Yougen Luo

{"title":"Hydrogen sulfide improved learning and memory deficits by reversing the inhibition of methylmercuric chloride on BDNF/TrkB signaling pathway.","authors":"Xiumei Cheng, Xinyi Cao, Yichun Yang, Lingxiao Wang, Yuxuan Yang, Yunjian Pan, Yongliang Zheng, Churong Wei, Yougen Luo","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Methylmercuric chloride (MMC) has neurotoxicity, while hydrogen sulfide (H2S) has shown inhibitory properties against nerve damage induced by various factors. The study aimed to investigate the impact of H2S on MMC-induced learning and memory impairment in mice and to explore the underlying mechanisms.Methods: A mouse model of learning and memory impairment was established by MMC gavage, and sodium hydrosulfide (NaHS) was used as an H2S donor for intervention. Cell viability and live/dead cell ratio in HT22 neuronal cells were assessed by CCK-8 assay and Calcein/PI staining, respectively. The Morris water maze test was performed to evaluate the learning and memory abilities of mice. Western blotting was utilized to determine protein expressions of BDNF and TrkB. The effects of H2S on MMC-induced learning and memory impairment were investigated based on the BDNF/TrkB pathways.Results: (1) MMC treatment decreased cell viability and reduced the ratio of live cells in HT22 cells, while H2S reversed these changes. (2) MMC prolonged escape latency, decreased platform crossing frequency, and reduced quadrant distance percentage of the platform in the Morris water maze test, while H2S reversed the above changes. (3)MMC downregulated BDNF and TrkB expression levels, while H2S suppressed these changes induced by MMC. (4)Treatment with 7, 8-DHF (a TrkB agonist) significantly attenuated MMC-induced prolonged escape latency and reduced platform crossing frequency.Conclusions: Our findings demonstrated that H2S ameliorated learning memory deficits in mice by reversing the inhibitory effects of MMC on BDNF/TrkB signaling pathway.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"45 4","pages":"281-288"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ruptured Lenticulostriate Artery Aneurysm Associated with Moyamoya Disease: A Case Report and Literature Review. 与莫亚莫亚氏病相关的韧带动脉瘤破裂：病例报告与文献综述

Neuro endocrinology letters Pub Date : 2024-11-04

Zheng Feng, Yongquan Chang, Xingyi Jin, Chao Fu

引用次数: 0