Neuro endocrinology letters最新文献_第3页

The river of life method in a schema therapy groups. 图式治疗小组中的生命之河法。

Neuro endocrinology letters Pub Date : 2024-01-31

Jan Prasko, Marie Ociskova, Julius Burkauskas, Jakub Vanek, Ilona Krone, Julija Gecaite-Stonciene, Marija Abeltina, Jelena Holomany, Milos Slepecky, Alicja Juskiene

引用次数: 0

Revisiting the role of TEG-PM in stroke prevention by drug selection for mono-antiplatelet medication following dual-antiplatelet treatment. 通过双抗血小板治疗后的单抗血小板药物选择，重新审视 TEG-PM 在中风预防中的作用。

Neuro endocrinology letters Pub Date : 2024-01-31

Lei Yan, Wenzhao Liang, Bingyang Zhao, Zhongyu Zhao, Kai Zhang, Lingling Wang, Jing Mang

{"title":"Revisiting the role of TEG-PM in stroke prevention by drug selection for mono-antiplatelet medication following dual-antiplatelet treatment.","authors":"Lei Yan, Wenzhao Liang, Bingyang Zhao, Zhongyu Zhao, Kai Zhang, Lingling Wang, Jing Mang","doi":"","DOIUrl":"","url":null,"abstract":"Backgrounds: Dual-antiplatelet therapy (DAPT) with aspirin and clopidogrel for minor strokes or TIAs has been demonstrated in several RCTs. Whether drug selection for mono-antiplatelet therapy (MAPT) following DAPT may influence stroke recurrence has not been clarified, especially for patients with intracranial atherosclerosis stenosis (ICAS). The Thrombelastography Platelet Mapping (TEG-PM) assay claimed to be capable of monitoring platelet function secondary to antiplatelet therapy.Purpose: The aim of this study was to investigate the preventive role of TEG-PM in individualized drug selection for MAPT following DAPT in patients with minor stroke or TIA.Methods: We retrospectively reviewed our patient database to identify individuals with minor stroke or TIA between February 2019 and July 2022. Patients were divided into ICAS and non-ICAS groups, and the efficacy and safety of TEG-PM-guided MAPT for stroke prevention after minor stroke or TIA were investigated in each group.Results: ICAS patients with TEG-PM-guided MAPT had lower rates of recurrent stroke than patients without TEG-PM guidance during a mean follow-up period of 18.1 months (6.3% vs 15.2%; p = 0.04). Patients without ICAS also tended to benefit from TEG-PM-guided MAPT with lower rates of stroke recurrence (2.6% vs 8.7%; p = 0.02). No difference in the safety outcome of any bleeding events was observed in patients with TEG-PM-guided MAPT and those without (ICAS group, 2.1% vs 3.0%; p = 0.68; non-ICAS group, 1.3% vs 2.3%; p = 0.79).Conclusion: The TEG-PM could be a tangible preprocessing in drug selection for MAPT following DAPT in patients with minor strokes or TIAs, especially for those with non-stented ICASs.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between COVID-19 vaccination and hair cortisol concentrations. 接种 COVID-19 疫苗与毛发皮质醇浓度之间的关系。

Neuro endocrinology letters Pub Date : 2024-01-31

Yuemin Ding, Yuxuan Xiong, Jingru Zhao, Ying Zhang, Qiang Zheng, Zulun Gao, Liuyi Lu, Kai Guo, Zhihao Bai, Hangdi Chen, Jiali Zhang, Meiyin Zhong, Aiwu Huang, Shiwei Duan, Xiong Zhang

{"title":"Association between COVID-19 vaccination and hair cortisol concentrations.","authors":"Yuemin Ding, Yuxuan Xiong, Jingru Zhao, Ying Zhang, Qiang Zheng, Zulun Gao, Liuyi Lu, Kai Guo, Zhihao Bai, Hangdi Chen, Jiali Zhang, Meiyin Zhong, Aiwu Huang, Shiwei Duan, Xiong Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Background: Cortisol is a steroid hormone secreted mainly by the adrenal cortex and is associated with chronic stress levels in the body. Hair cortisol concentration (HCC) is a reliable index to assess human stress levels. So far, no study has reported whether COVID-19 vaccination is associated with the changes of HCC.Methods: Hair samples were collected from 114 college students at Hangzhou City University and Zhejiang University. Among them, 57 cases completed COVID-19 vaccination and others did not. HCCs were measured by the chemiluminescence immunoassay (CLIA). The psychological stress levels were evaluated using the Chinese College Student Psychological Stress Scale (CCSPSS). General information and adverse reactions of the subjects were collected by questionnaire.Results: Compared with the vaccinated college students, the unvaccinated students had higher HCC levels in both A and B hair segments respectively corresponding older or six weeks before and newer or six weeks after vaccination (p < 0.05), reflecting higher stress levels. Besides, the vaccinated group had significantly higher HCCs in segment B compared with segment A (p < 0.05). Further analysis showed that the value of ΔHCC (HCCseg.B - HCCseg.A) of the vaccinated group was strongly associated with COVID-19 vaccination (p < 0.05), but was not associated with age, gender, BMI, CCSPSS score, hormone use, exercise frequency, hair washing frequency, or hair treatment. Finally, the number of self-reported systemic adverse reactions in the vaccinated group was associated with ΔHCC (p < 0.01).Conclusion: The COVID-19 vaccination had an impact on the value of HCC, which might be linked to the occurrence of systemic adverse effects following vaccinations.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring self-care within the context of cognitive behavioural therapy and supervision. 在认知行为疗法和督导的背景下探索自我保健。

Neuro endocrinology letters Pub Date : 2024-01-31

Jan Prasko, Marija Abeltina, Julija Gecaite-Stonciene, Julius Burkauskas, Ilona Krone, Erika Jurisova, Marta Zatkova, Jakub Vanek, Milos Slepecky, Marie Ociskova

{"title":"Exploring self-care within the context of cognitive behavioural therapy and supervision.","authors":"Jan Prasko, Marija Abeltina, Julija Gecaite-Stonciene, Julius Burkauskas, Ilona Krone, Erika Jurisova, Marta Zatkova, Jakub Vanek, Milos Slepecky, Marie Ociskova","doi":"","DOIUrl":"","url":null,"abstract":"This article emphasizes the critical role of self-care in the professional lives of cognitive behavioural therapy (CBT) therapists and supervisors. It delves into the importance of self-care, elucidating its significance in maintaining therapists' mental health and effectiveness. The article presents a range of practical strategies that promote self-care, providing therapists and supervisors with specific steps to incorporate self-care into their daily routines. Moreover, the article explores common challenges and barriers to self-care, such as a lack of time, feelings of guilt associated with prioritizing one's needs, and a lack of available resources for self-care. The article aims to deepen our understanding of the complexities of practising self-care by shedding light on possible obstacles. In addition, the article includes case vignettes that demonstrate tangible examples of the positive impact of self-care on therapists' mental health and effectiveness. The overarching goal of this article is to encourage ongoing discussion and research on self-care. It advocates a greater emphasis on self-care in CBT and CBT supervision (CBTS), intending to promote the health and well-being of those who dedicate their lives to caring for others. The insights and strategies presented in this article serve as a resource for therapists and supervisors striving to achieve a balanced lifestyle while effectively catering to the needs of their clients.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standard low-resolution electromagnetic tomography imaging of brain for the analysis of mental fatigue during a simulated air traffic control task. 标准低分辨率电磁断层扫描脑成像，用于分析模拟空中交通管制任务中的精神疲劳。

Neuro endocrinology letters Pub Date : 2023-12-12

Lin Cong, Meiqing Huang, Jinghua Yang, Shan Cheng, Chaolin Teng, Kaiwen Xiong, Taihui Zhang, Weitao Dang, Cui Liu, Jin Ma, Wendong Hu

{"title":"Standard low-resolution electromagnetic tomography imaging of brain for the analysis of mental fatigue during a simulated air traffic control task.","authors":"Lin Cong, Meiqing Huang, Jinghua Yang, Shan Cheng, Chaolin Teng, Kaiwen Xiong, Taihui Zhang, Weitao Dang, Cui Liu, Jin Ma, Wendong Hu","doi":"","DOIUrl":"","url":null,"abstract":"Background: Standard low-resolution electromagnetic tomography (sLORETA) was used to accurately detect EEG changes in mental fatigue of air traffic controllers (ATCo) under a simulated air traffic control (ATC) task. We explored the changes in standard current density, activated cortical intensity, and brain source location.Methods: The participants were instructed to use the tower flight command simulation training system for three hours of uninterrupted ATC task. The 3-hour EEG signal was divided into four stages: task start, 1st hour, 2nd hour, and task end. Each stage was preprocessed for 3 minutes to explore the EEG changes and then processed by sLORETA in a statistical non-parametric mapping analysis.Results: The current density distribution of δ and α oscillations differed significantly during the four tasks, while θ, β and γ oscillations did not. Changes in δ oscillations of the brain during mental fatigue were detected mainly in the postcentral gyrus (BA2 and BA3), precentral gyrus (BA4 and BA6), inferior temporal gyrus (BA20), and superior temporal gyrus (BA38). The α oscillations were found mainly decreased in the postcentral gyrus (BA2) and inferior parietal lobule (BA40) when the task was in progress compared with the end of the task.Conclusion: The superior temporal gyrus and somatosensory cortex were the main activated cortical regions during the simulated ATC task. The α and δ oscillations showed contrasting activity during simulated ATC task, which might reflect the release of task-relevant brain's areas from inhibition and enhance the neural activity.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese. 关于日本人积极移情和特质宽容相关基因多态性的探索性研究。

Neuro endocrinology letters Pub Date : 2023-12-12

Masahiro Matsunaga, Yohsuke Ohtsubo, Takahiko Masuda, Yasuki Noguchi, Hidenori Yamasue, Keiko Ishii

{"title":"Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese.","authors":"Masahiro Matsunaga, Yohsuke Ohtsubo, Takahiko Masuda, Yasuki Noguchi, Hidenori Yamasue, Keiko Ishii","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: Previous studies have indicated that good human relationships contribute significantly to subjective well-being. We recently focused on two important ways of developing good interpersonal relationships: positive empathy, which focuses on the happiness of other people, and trait forgivingness, a tendency to forgive others. We novelly conducted an exploratory genome-wide association study (GWAS) to identify candidate gene polymorphisms associated with positive empathy and trait forgivingness among the Japanese.Material and methods: We for the first time identified several genetic polymorphisms associated with positive empathy and trait forgivingness through the GWAS based on a small sample population and relatively low threshold. We subsequently validated three genetic polymorphisms from these candidate genes using a real-time polymerase chain reaction system.Results: The results demonstrated that polymorphism in the vomeronasal type-1 receptor 1 (VN1R1) (rs61744949), a putative human pheromone receptor, is associated with positive empathy. In addition, genetic polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 7 (HTR7: rs77843021) and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE: rs9908013), which are associated with dopamine and serotonin biosynthesis, are associated with trait forgivingness.Conclusion: This study novelly illustrated the influence of the genetic polymorphism in VN1R1 on positive empathy and that of genetic polymorphisms in HTR7 and YWHAE on trait forgivingness. It identified a relationship between previously unreported genetic polymorphisms and the necessary abilities for developing good human relationships. This will significantly impact future research on positive psychology and social psychology.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary microalbumin/creatinine ratio is a predictor of the occurrence and severity of leukoaraiosis. 尿微量白蛋白/肌酐比值可预测白癫风的发生和严重程度。

Neuro endocrinology letters Pub Date : 2023-12-12

PingPing Jin, ShanShan Ye, Hua Ye, QiaoWen Tong, QingYuan Zhang

{"title":"Urinary microalbumin/creatinine ratio is a predictor of the occurrence and severity of leukoaraiosis.","authors":"PingPing Jin, ShanShan Ye, Hua Ye, QiaoWen Tong, QingYuan Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the correlation between the urinary microalbumin/creatinine ratio (UACR) and the occurrence and severity of leukoaraiosis.Methods: A total of 323 patients were retrospectively recruited. Demographic, clinical, and laboratory data were collected at the time of admission, and the UACR was calculated based on the levels of urinary microalbumin and creatinine. All patients showed improvement in cranial magnetic resonance imaging (MRI) examination. The subjects were divided into leukoaraiosis and non-leukoaraiosis groups according to the results of the cranial MRI examination. According to the Fazekas standard score, the patients in the leukoaraiosis group were divided into the mild leukoaraiosis group: Fazekas (1-2 points), moderate leukoaraiosis group: Fazekas (3-4points); and severe leukoaraiosis group: Fazekas (5-6 points).Results: A regression analysis was performed to adjust for confounding factors. (1) Compared with the non-leukoaraiosis group, UACR level was higher in the leukoaraiosis group at admission, and the difference between the groups was statistically significant (p < 0.05). (2) In the multivariate logistic regression analysis, UACR was correlated with the occurrence of leukoaraiosis, which may be an independent risk factor. (3) The UACR levels increased gradually in the mild, moderate and severe leukoaraiosis groups, and the difference was statistically significant (p< 0.05). (4) In the ordered multi-category logistic regression analysis, UACR was correlated with the severity of leukoaraiosis, which may be an independent risk factor.Conclusion: UACR is associated with the occurrence and severity of leukoaraiosis, and may be an independent risk factor.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness. 非功能性垂体腺瘤中Claudin-9、酪氨酸激酶-2和转录信号转导和激活因子-3的表达与侵袭性的相关性。

Neuro endocrinology letters Pub Date : 2023-12-12

Abudukadier Yasen, Maimaitiyiming Tuoheti, Ba Tu, Cheng Zhang, Yu Ding, Fey Tang, Yonggang Wu

{"title":"The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness.","authors":"Abudukadier Yasen, Maimaitiyiming Tuoheti, Ba Tu, Cheng Zhang, Yu Ding, Fey Tang, Yonggang Wu","doi":"","DOIUrl":"","url":null,"abstract":"Background: Deeper studies on the pathological mechanism associated with invasiveness of non-functioning pituitary adenoma (NFPA) is imperative to find better treatments. This research was preliminarily conducted to investigate the correlation between the expression of Claudin-9 (CLDN9), Tyrosine kinase-2 (TYK2), Signal transducers and activators of transcription-3 (STAT3) and invasiveness in NFPA to illustrate the pathological mechanism.Methods: Clinical data and surgical specimens of 12 patients with NFPA were collected and divided into invasive and non-invasive NFPA groups, comprising six patients for each group. CLDN9, TYK2 and STAT3 transcription and expression levels in the NFPA tissues of the two groups were detected by quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting (WB) and immunohistochemistry (IHC). The lentiviral plasmid transfection technique was used to develop a rat pituitary tumour GT1-1 cell line null control group (NC) and CLDN9-overexpressed experimental group (OE-CLDN9), and TYK2 and STAT3 transcription levels in the NC and OE-CLDN9 cell groups were detected using qRT-PCR.Results: The CLDN9 and STAT3 expressions were significantly higher in invasive than in non-invasive NFPA tissues, whereas the TYK2 expression in invasive NFPA tissues was significantly lower than that in non-invasive NFPA (p < 0.001); The STAT3 upregulated (p < 0.001) and the TYK2 downregulated (p < 0.01) after the CLDN9 overexpression.Conclusion: Upregulated CLDN9 may increase the NFPA invasiveness through STAT3. In addition, low TYK2 expression might enhance the invasiveness in NFPA, which needs further studies to confirm. These results could provide a promising research leads for targeted treatment of NFPA.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination therapy for patients with a developmental dysphasia: selected approaches based on special education, rehabilitation and psychology in a systematic case study. 发育性失语症患者的综合治疗：系统案例研究中基于特殊教育、康复和心理学的选定方法。

Neuro endocrinology letters Pub Date : 2023-12-12

Michal Vostrý, Ilona Pešatová, Barbora Lanková, Otakar Fleischmann, Jaroslava Jelínková, Ivana Štolová, Radka Beranová, Nikola Mundoková

{"title":"Combination therapy for patients with a developmental dysphasia: selected approaches based on special education, rehabilitation and psychology in a systematic case study.","authors":"Michal Vostrý, Ilona Pešatová, Barbora Lanková, Otakar Fleischmann, Jaroslava Jelínková, Ivana Štolová, Radka Beranová, Nikola Mundoková","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The paper deals with the possibilities of the development and the support of individuals with developmental dysphasia with regard to the legislative framework of the Czech Republic in the field of education and presents the results of a systematic case study of a child patient diagnosed with developmental dysphasia (according to ICD-10; F80.1 and F80.2).Case report: The study aimed to determine the effect of combined therapy using long-term special educational, rehabilitation and psychological intervention, speech therapy and music therapy on the development of the patient's communication skills. The proband was selected by random, stratified sampling based on pre-determined relevant characteristics (age 6 years i.e., before entering primary school, diagnosed with developmental dysphasia). A 6-year-old child patient participated in the research with the consent of the legal representative. The therapy was focused on special educational care, speech therapy, music therapy and psychological intervention (including psychotherapy). During the hospitalization and post-hospitalization care, there was also the presence of a physiotherapist and an occupational therapist.Conclusion: The results of the research point out the need for regular and close multidisciplinary cooperation of an occupational therapist, a physiotherapist, a special educator, a speech therapist, a music therapist and a psychologist when working with patients diagnosed with developmental dysphasia. These professions focus specifically on specific areas of support with a focus on cognitive, phatic and motor functions with the support of social adaptability.","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Loss of Consciousness and Prolonged Convulsions Due to Amanita Pantherina Intoxication. 天南星中毒导致意识丧失和长时间抽搐。

Neuro endocrinology letters Pub Date : 2023-12-12

Lukáš Handl, Martin Nováček, Robin Šín, Lenka Čechurová

引用次数: 0