Minerva medicaPub Date : 2024-06-13DOI: 10.23736/S0026-4806.24.09355-8
Fabio Caputo, Lisa Lungaro, Matteo Guarino, Anna Costanzini, Giacomo Caio, Gianni Testino, Roberto DE Giorgio
{"title":"Alcohol-related diseases: from metabolism to the main effect on the body.","authors":"Fabio Caputo, Lisa Lungaro, Matteo Guarino, Anna Costanzini, Giacomo Caio, Gianni Testino, Roberto DE Giorgio","doi":"10.23736/S0026-4806.24.09355-8","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09355-8","url":null,"abstract":"<p><p>Alcohol consumption can cause, beyond addiction, roughly 200 different diseases and at least fourteen types of cancer. In 2016 the WHO estimated that 29% of alcohol-related deaths were mainly due to oncological diseases, liver cirrhosis (20%), and cardiovascular disorders (19%). The aim of this review was to focus on the absorption and metabolism of ethanol and discuss the main conditions caused by alcohol consumption (i.e., liver and cardiovascular diseases, and tumors). This narrative review is based on a detailed analysis of the scientific literature published before January 31, 2024 (PubMed, Web of Science, Scopus, Google Scholar). Approximately 90% of the absorbed alcohol reaches the liver where it is metabolized to acetaldehyde, a highly reactive and toxic compound. The excessive use of alcohol causes damage to several organs and systems, mainly the liver (e.g., steatosis, steato-hepatitis, fibrosis, and cirrhosis), cardiovascular system (cardiomyopathy, arrythmias, arterial hypertension, and stroke), and significantly contribute to the onset of neoplastic lesions to various organs including the esophagus, liver and breast. Even moderate drinking appears not to reduce mortality risk. Alcohol intake is one of the main risk factors for several pathological conditions and social problems, thus drastically impacting on public health. Proper awareness of the high risk related to alcohol consumption is of crucial importance to reduce the harm to public health.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-12DOI: 10.23736/S0026-4806.24.09108-0
Bowen Zhao, Shishi Huang, Lu Fang
{"title":"Exploration of biomarkers of coronary atherosclerotic heart disease.","authors":"Bowen Zhao, Shishi Huang, Lu Fang","doi":"10.23736/S0026-4806.24.09108-0","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09108-0","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-12DOI: 10.23736/S0026-4806.24.09412-6
Wei Liu, Yinhao He, Tiezhu Chen, Zixuan Lv
{"title":"Effects of different doses of psoralen on lower extremity biomechanical characteristics in elderly patients with knee osteoarthritis.","authors":"Wei Liu, Yinhao He, Tiezhu Chen, Zixuan Lv","doi":"10.23736/S0026-4806.24.09412-6","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09412-6","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-12DOI: 10.23736/S0026-4806.24.09395-9
Rui Li, Yue Wang, Xiaoxia Zhu, Chongge Yang, Congbing Yan
{"title":"Nursing value of clinical stratification model in COPD.","authors":"Rui Li, Yue Wang, Xiaoxia Zhu, Chongge Yang, Congbing Yan","doi":"10.23736/S0026-4806.24.09395-9","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09395-9","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One case of Sweet Syndrome after treatment of MDS-RS-MLD with azactidine and literature review.","authors":"Zhenzhen Liu, Yang Wang, Lili Qin, Nannan Lv, Haiying Wang, Anhua Feng","doi":"10.23736/S0026-4806.24.09405-9","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09405-9","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-12DOI: 10.23736/S0026-4806.24.09432-1
Fangying Zhu, Chenghong Yu
{"title":"Effect of dexzopiclone combined with horizontal Baduanjin on sleep quality in diabetic patients with heart failure and insomnia.","authors":"Fangying Zhu, Chenghong Yu","doi":"10.23736/S0026-4806.24.09432-1","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09432-1","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-12DOI: 10.23736/S0026-4806.24.09406-0
Shiwei Yang, Shanyu Gao, Tongming Liu, Junning Liu
{"title":"A case of rhabdomyosarcoma with perianal swelling and pain.","authors":"Shiwei Yang, Shanyu Gao, Tongming Liu, Junning Liu","doi":"10.23736/S0026-4806.24.09406-0","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09406-0","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-05DOI: 10.23736/S0026-4806.24.09367-4
Yifei Sun, Chunxiao Hu, Yongtao Su
{"title":"Bioinformatics analysis of the prognostic value of ADH1B gene in diabetic foot ulcer.","authors":"Yifei Sun, Chunxiao Hu, Yongtao Su","doi":"10.23736/S0026-4806.24.09367-4","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09367-4","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}