Mayo Clinic proceedings. Innovations, quality & outcomes最新文献

{"title":"Comparative Analysis of Coronavirus disease 2019 Vaccine Efficacy in Heart Transplant Recipients on Standardized Immunotherapy Regimens","authors":"Shriya Sharma MBBS ,&nbsp;Jose Ruiz MD ,&nbsp;Rohan Goswami MD","doi":"10.1016/j.mayocpiqo.2024.03.006","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.03.006","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the effect of coronavirus disease 2019 (COVID-19) infection on heart transplant recipients requiring immunotherapy. To investigate the effectiveness of vaccination in immunosuppressed heart transplant recipients during the initial years of the COVID-19 pandemic, and to examine the timing of COVID-19 infections in heart transplant recipients’ posttransplantation.</p></div><div><h3>Patients and Methods</h3><p>International data on COVID-19 infection in immunosuppressed populations is limited. Heart transplant recipients requiring immunotherapy are at risk for increased complications with COVID-19 infection. The availability of vaccination and temporal trends in this population has not been well described. We report outcomes in immunosuppressed patients during the initial years of the COVID-19 pandemic from March 1, 2019, to October 31, 2021, at Mayo Clinic in Florida.</p></div><div><h3>Results</h3><p>A total of 98 patients were reviewed, of which 49 were COVID-19–positive (CP), and 49 were negative (CN). The cohort was well matched, with a median age of 58 years (49–65 years) in both groups. Females consisted of 41% in the CP group and 18.4% in the CN group. Immunosuppression was not significantly different for CP or CN patients. The median time from transplant to CP was 384 days (237–677 days). The CN group’s median follow-up after transplant was 947 days (737–1191 days). The CP hospitalization rate was 24% with only 1 death. More CP patients were vaccinated than the CN group (92% vs 78%, <em>P</em>=.025).</p></div><div><h3>Conclusion</h3><p>Our study sheds light on COVID-19’s effect on heart transplant recipients and vaccination in this population. Our findings suggest a potentially heightened infection risk within the first 1.5 years posttransplant, highlighting the need to optimize management strategies and vaccine efficacy in this vulnerable group.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S254245482400016X/pdfft?md5=b13b7a1948941ea314fb34482e3f38fc&pid=1-s2.0-S254245482400016X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second Victim Experiences of Health Care Learners and the Influence of the Training Environment on Postevent Adaptation","authors":"Lily Huang BA ,&nbsp;Kirsten A. Riggan MA, MS ,&nbsp;Vanessa E. Torbenson MD ,&nbsp;Alayna K. Osborne BLA ,&nbsp;Sherry S. Chesak PhD, RN ,&nbsp;Robyn E. Finney DNAP ,&nbsp;Megan A. Allyse PhD ,&nbsp;Enid Y. Rivera-Chiauzzi MD","doi":"10.1016/j.mayocpiqo.2024.03.004","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.03.004","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the experience of medical and graduate learners with second victim experience (SVE) after medical errors or adverse patient outcomes, including impact on training and identification of factors that shape their postevent recovery.</p></div><div><h3>Patients and Methods</h3><p>The validated Second Victim Experience and Support Tool-Revised (SVEST-R), Physician Well-Being Index, and supplemental open-ended questions were administered to multidisciplinary health care learners between April 8, 2022, and May 30, 2022, across a large academic health institution. Open-ended responses were qualitatively analyzed for iterative themes related to impact of SVE on the training experience.</p></div><div><h3>Results</h3><p>Of the 206 survey respondents, 144 answered at least 1 open-ended question, with 62.1% (n=91) reporting at least 1 SVE. Participants discussed a wide range of SVEs and indicated that their postevent response was influenced by their training environment. Lack of support from supervisors and staff exacerbated high stress situations. Some trainees felt blamed and unsupported after a traumatic experience. Others emphasized that positive training experiences and supportive supervisors helped them grow and regain confidence. Learners described postevent processing strategies helpful to their recovery. Some, however, felt disincentivized from seeking support.</p></div><div><h3>Conclusion</h3><p>This multidisciplinary study of learners found that the training environment was influential in postevent recovery. Our findings support the need for the inclusion of education on SVEs and adaptive coping mechanisms as part of health care professional educational curriculums. Educators and health care staff may benefit from enhanced education on best practices to support trainees after stressful or traumatic patient events.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000146/pdfft?md5=a3e08f64fc27afd23d9ade7aa9dbd4ef&pid=1-s2.0-S2542454824000146-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140645325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of a Cancer Registry Versus Clinical Care Team Chart Abstraction in Identifying Cancer Recurrence","authors":"Elsa A. Sutton MD ,&nbsp;Benjamin C. Kamdem Talom BA ,&nbsp;Daniel K. Ebner MD, MPH ,&nbsp;Taylor M. Weiskittel MS ,&nbsp;William G. Breen MD ,&nbsp;Roman O. Kowalchuk MD ,&nbsp;Heather J. Gunn PhD ,&nbsp;Courtney N. Day MS ,&nbsp;Eric J. Moore MD ,&nbsp;Sara J. Holton CTR, BS Health/Health Care Administration/Management ,&nbsp;Kathryn M. Van Abel MD ,&nbsp;Chadi N. Abdel-Halim MD ,&nbsp;David M. Routman MD ,&nbsp;Mark R. Waddle MD","doi":"10.1016/j.mayocpiqo.2024.03.005","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.03.005","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the completeness and reliability of recurrence data from an institutional cancer registry for patients with head and neck cancer.</p></div><div><h3>Patients and Methods</h3><p>Recurrence information was collected by radiation oncology and otolaryngology researchers. This was compared with the institutional cancer registry for continuous patients treated with radiation therapy for head and neck cancer at a tertiary cancer center. The sensitivity and specificity of institutional cancer registry data was calculated using manual review as the gold standard. False negative recurrences were compared to true positive recurrences to assess for differences in patient characteristics.</p></div><div><h3>Results</h3><p>A total of 1338 patients who were treated from January 1, 2010, through December 31, 2017, were included in a cancer registry and underwent review. Of them, 375 (30%) had confirmed cancer recurrences, 45 (3%) had concern for recurrence without radiologic or pathologic confirmation, and 31 (2%) had persistent disease. Most confirmed recurrences were distant (37%) or distant plus locoregional (29%), whereas few were local (11%), regional (9%), or locoregional (14%) alone. The cancer registry accuracy was 89.4%, sensitivity 61%, and specificity 99%. Time to recurrence was associated with registry accuracy. True positives had recurrences at a median of 414 days vs 1007 days for false negatives.</p></div><div><h3>Conclusion</h3><p>Currently, institutional cancer registry recurrence data lacks the required accuracy for implementation into studies without manual confirmation. Longer follow-up of cancer status will likely improve sensitivity. No identified differences in patients accounted for differences in sensitivity. New, ideally automated, data abstraction tools are needed to improve detection of cancer recurrences and minimize manual chart review.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000158/pdfft?md5=bf5abceedb4c15e1a256e36e01002b88&pid=1-s2.0-S2542454824000158-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140622483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergency Department Visits Before Cancer Diagnosis Among Women at Mayo Clinic","authors":"Sally K. Stauder BS ,&nbsp;Shalmali R. Borkar MBBS, MPH ,&nbsp;Amy E. Glasgow MHA ,&nbsp;Tage L. Runkle MA ,&nbsp;Mark E. Sherman MD ,&nbsp;Aaron C. Spaulding PhD ,&nbsp;Michael M. Mohseni MD ,&nbsp;Christopher C. DeStephano MD, MPH","doi":"10.1016/j.mayocpiqo.2024.03.002","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.03.002","url":null,"abstract":"<div><h3>Objective</h3><p>To determine associations of incident cancer diagnoses in women with recent emergency department (ED) care.</p></div><div><h3>Patients and Methods</h3><p>A retrospective cohort study analyzing biological females aged 18 years and older, who were diagnosed with an incident primary cancer (12 cancer types studied) from January 1, 2015, to December 31, 2021, from electronic health records. The primary outcome was a cancer diagnosis within 6 months of a preceding ED visit. Secondary outcomes included patient factors associated with a preceding ED visit.</p></div><div><h3>Results</h3><p>Of 25,736 patients (median age of 62 years, range 18-101) diagnosed with an incident primary cancer, 1938 (7.5%) had an ED visit ≤6 months before a diagnosis. The ED-associated cancer cases were highest in lung cancer (n=514, 14.7%) followed by acute lymphoblastic leukemia (n=22, 13.3%). Patient factors increasing the likelihood of ED evaluation before diagnosis included 18-50 years of age (OR=1.32; 95% CI, 1.09-1.61), Elixhauser score (measure of comorbidities) &gt;4 (OR=17.90; 95% CI, 14.21-22.76), use of Medicaid or other government insurance (OR=2.10; 95% CI, 1.63-2.69), residence within the institutional catchment areas (OR=3.18; 95% CI, 2.78-3.66), non-Hispanic Black race/ethnicity (OR=1.41; 95% CI, 1.04-1.88), and established primary care provider at Mayo Clinic (OR=1.45; 95% CI, 1.28-1.65). The ED visits were more likely in those who died within 6 months of diagnosis (n=327, 37.8%) than those who did not die (n=1611, 6.5%).</p></div><div><h3>Conclusion</h3><p>Patient characteristics identified in this study offer opportunities to provide cancer risk assessment and health navigation, particularly among individuals with comorbidities and limited health care access.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000122/pdfft?md5=d0c6ab1674cb5c9c76aef60175aad8e3&pid=1-s2.0-S2542454824000122-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140347059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Employee Dietary Initiative Improved Chronic Symptoms","authors":"Nancy L. Sudak MD ,&nbsp;Melissa L. Harry MSW, PhD","doi":"10.1016/j.mayocpiqo.2024.03.001","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.03.001","url":null,"abstract":"<div><p>With the awareness that the Standard American Diet is a critical contributor to chronic diseases, this initiative aimed to assess the effects of a 28-day dietary challenge health care improvement project on health system employee energy level, sleep quality, gastrointestinal function, ability to concentrate, and aches/pains, including the impact of adherence level, during a period of restricted intake of gluten, dairy, and sugar offered annually from 2021 to 2023. A total of 754 employees completed the pre-challenge survey; analyses included 354 employees who completed both pre-challenge and post-challenge surveys in at least 1 year of this project. Wilcoxon signed rank tests compared presurvey and postsurvey responses to self-reported energy level, sleep quality, gastrointestinal function, ability to concentrate, and aches/pains. Analysis of variance with Tukey’s honestly significant difference tests compared self-reported adherence level with change scores, with η² representing effect size. In each challenge year, the mean rank levels of energy, sleep quality, gastrointestinal function, concentration, and aches/pains improved significantly between pre-surveys and post-surveys (all <em>P</em>&lt;.001). Although an association between significant positive change and diet adherence level was found for all items in at least 1 challenge year, those who mostly or completely adhered to the challenge diet restrictions reported significantly greater positive change in energy levels and gastrointestinal symptoms than those who did not or minimally adhered in all challenge years, with small to medium effect sizes. In conclusion, Essentia Health’s employee challenge appeared to improve self-reported outcomes in 5 symptom domains, with energy levels and gastrointestinal symptoms correlating most favorably to adherence to the challenge. These findings have health and cost implications, which could be confirmed by formal research in employee and other populations.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000110/pdfft?md5=02ce49ae4a6be35062abc86901a38bd2&pid=1-s2.0-S2542454824000110-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140345245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy-Associated Cancer: A Systematic Review and Meta-Analysis","authors":"Ben Walters MBChB ,&nbsp;India Midwinter BSc, MBBS ,&nbsp;Carolyn A. Chew-Graham MBChB, MD ,&nbsp;Kelvin P. Jordan PhD ,&nbsp;Garima Sharma MB ,&nbsp;Lucy C. Chappell MB, BCh, PhD ,&nbsp;Emma J. Crosbie MBChB, PhD ,&nbsp;Purvi Parwani MBBS, MPH ,&nbsp;Mamas A. Mamas BM BCh, DPhil ,&nbsp;Pensée Wu MBChB, MD(Res)","doi":"10.1016/j.mayocpiqo.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.02.002","url":null,"abstract":"<div><p>This study aimed to systematically evaluate and quantify the risk of adverse maternal and neonatal outcomes in patients with pregnancy-associated cancer (PAC). This study was conducted from February 13, 2021, through July 24, 2023. A systematic search of MEDLINE, Embase, Web of Science Core Collection, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials was conducted to identify studies reporting outcomes for patients with PAC. The study was registered on PROSPERO. Two reviewers independently conducted screening, data extraction, and quality assessment. The associations were quantified using random-effects meta-analysis. The initial search produced 29,401 titles and abstracts, after which 147 unique full-text articles were screened, of which 22 articles with 59,190 pregnancies with PAC from 70,097,167 births were included in the meta-analysis. Women with PAC were at significantly increased risk of cesarean deliveries (risk ratio [RR], 1.58; 95% CI, 1.31-1.89), preterm birth (RR, 3.07; 95% CI, 2.37-3.98), venous thromboembolism (RR, 6.76; 95% CI, 5.08-8.99), and maternal death (RR, 41.58; 95% CI, 20.38-84.83). The only outcome with reduced risk was instrumental mode of delivery (RR, 0.67; 95% CI, 0.52-0.87). Pregnancy-associated cancer increases risk of adverse outcomes, including a 7-fold risk of venous thromboembolism and a 42-fold risk of maternal death. Further research is required to better understand the mechanisms leading to these adverse outcomes, especially for women who are not diagnosed until the postpartum period. Affected women should have counseling regarding their increased risk of adverse outcomes.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000109/pdfft?md5=169a6d692819e0adfc18b447adb93d25&pid=1-s2.0-S2542454824000109-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart failure?","authors":"Shriya Sharma MBBS,&nbsp;Rohan Goswami MD","doi":"10.1016/j.mayocpiqo.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.02.001","url":null,"abstract":"","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000092/pdfft?md5=35819c16ed5d8de713c78d95544ba8f7&pid=1-s2.0-S2542454824000092-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140052820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle Factors and Cancer: A Narrative Review","authors":"Reya Sharman MD, MPH ,&nbsp;Zoey Harris MD ,&nbsp;Brenda Ernst MD ,&nbsp;Dawn Mussallem DO ,&nbsp;Ashley Larsen MS ,&nbsp;Krisstina Gowin DO","doi":"10.1016/j.mayocpiqo.2024.01.004","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.01.004","url":null,"abstract":"<div><p>Lifestyle factors and their impact on cancer prevention, prognosis, and survivorship are increasingly recognized in the medical literature. Lifestyle factors are primarily defined here as diet and physical activity. We conducted a narrative review of the primary published data, including randomized controlled trials and prospective studies, on the impact of primary lifestyle factors on oncogenesis and clinical outcomes in the preventative and survivorship setting. First, we discuss the oncogenic mechanisms behind primary lifestyle factors (diet, physical activity and, within these 2, obesity). Then, we discuss the impact of adherence to lifestyle guidelines and dietary patterns on cancer incidence based on primary data. Owing to the plethora of published literature, to summarize the data in a more efficient manner, we describe the role of physical activity on cancer incidence using summative systematic reviews. We end by synthesizing the primary data on lifestyle factors in the survivorship setting and conclude with potential future directions. In brief, the various large-scale studies investigating the role diet and physical activity have reported a beneficial effect on cancer prevention and survivorship. Although the impact of single lifestyle factors on cancer incidence risk reduction is generally supported, holistic approaches to address the potential synergistic impact of multiple lifestyle factors together in concert is limited. Future research to identify the potentially synergistic effects of lifestyle modifications on oncogenesis and clinical outcomes is needed, particularly in cancer subtypes beyond colorectal and breast cancers.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000080/pdfft?md5=d0ee4432474cab4ebc217bdcc193ca83&pid=1-s2.0-S2542454824000080-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promise of Lifestyle Medicine for Heart Disease, Diabetes Mellitus, and Cerebrovascular Diseases","authors":"Aleksandra Pikula MD ,&nbsp;Mahima Gulati MD, MSc ,&nbsp;Jonathan P. Bonnet MD, MPH ,&nbsp;Sarah Ibrahim MN, PhD ,&nbsp;Svetlana Chamoun MD, PhD ,&nbsp;Andrew M. Freeman MD ,&nbsp;Koushik Reddy MD","doi":"10.1016/j.mayocpiqo.2023.11.005","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2023.11.005","url":null,"abstract":"<div><p>The burden of noncommunicable chronic diseases has relevant and negative consequences to persons, health care systems, and economies worldwide. Chronic diseases are the leading cause of disability and mortality and are responsible for 90% of health care expenditure. The most common chronic diseases are diabetes mellitus (DM), cardiovascular disease, and cerebrovascular disease (stroke and vascular cognitive impairment). Modifiable risk factors (MRFs) for these conditions include hypertension, hyperlipidemia, smoking, poor diet, and low-physical activity; with hypertension being the most prevalent MRF. Most MRFs can be successfully targeted through lifestyle medicine (LSM), which is a medical specialty that addresses the root causes of chronic diseases through its primary, secondary, and tertiary preventative approaches. Lifestyle medicine comprises 6 pillars (nutrition, physical activity, sleep health, stress reduction, social connections, and substance use) which through various behavioral approaches, focus on regular physical activity, healthy eating, good quality and quantity sleep, and meaningful social connections coupled with the reduction of stress and substance use. This paper will briefly review the evidence and promise of individual LSM pillars in addressing the underlying MRFs of DM, cardiovascular and cerebrovascular disease (specifically stroke and vascular cognitive impairment). Lifestyle medicine holds a great promise for comprehensive and much improved population health. However, the adoption of LSM at the societal scale requires a multifaceted approach and widespread integration would galvanize a paradigm shift to prevent, treat or reverse chronic diseases from the root causes and achieve health equity.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000031/pdfft?md5=58d78cea9d5fe151634311a29262b548&pid=1-s2.0-S2542454824000031-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139985022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Series of Minimally Invasive Robotic-Assisted Resection of Cardiac Papillary Fibroelastoma: The Mayo Clinic Experience","authors":"Ali Ahmad MD ,&nbsp;Edward A. El-Am MD ,&nbsp;Piotr Mazur MD, PhD ,&nbsp;Elias Akiki MD ,&nbsp;Ahmed A. Sorour MD ,&nbsp;Reto D. Kurmann MD ,&nbsp;Kyle W. Klarich MD ,&nbsp;Arman Arghami MD, MPH ,&nbsp;Phillip G. Rowse MD ,&nbsp;Richard C. Daly MD ,&nbsp;Joseph A. Dearani MD","doi":"10.1016/j.mayocpiqo.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.mayocpiqo.2024.01.001","url":null,"abstract":"<div><p>Papillary fibroelastomas (PFEs) are small, slowly growing benign cardiac tumors with clinically significant risk of embolization. Surgical excision is the definitive treatment of symptomatic PFE and is conventionally performed through a median sternotomy. In this study, we report a series of 12 patients, who underwent robotic-assisted PFE removal at the Mayo Clinic. PFE involved the mitral valve, left atrium, and tricuspid valve. No major complications occurred after the procedure, and most patients were discharged 4 days after the surgery. On follow-up, 1 patient demonstrated pericarditis.</p></div>","PeriodicalId":94132,"journal":{"name":"Mayo Clinic proceedings. Innovations, quality & outcomes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2542454824000018/pdfft?md5=fd8dda6c79e48af2268a31af1219db9b&pid=1-s2.0-S2542454824000018-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139942255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}