Materia socio-medica最新文献

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The Comparative Study of the Administration of the Combination Preparation of Isoflavones and Hyaluronic Acid in Menopausal Women for the Treatment of the Symptoms of Menopause, Urogenital Atrophy and Oteoporosis in Relation to Existing Hormone Replacement Therapies. 异黄酮和透明质酸联合制剂在更年期妇女中的应用与现有激素替代疗法治疗更年期、泌尿生殖系统萎缩和耳孔症症状的比较研究。
Materia socio-medica Pub Date : 2023-09-01 DOI: 10.5455/msm.2023.35.206-214
Anna Chalkidou, Efthimios Oikonomou, Dimitrios Lambrinos, Anastasia Bothou, Dimitrios Kyriakou, Konstantinos Nikolettos, Georgios Marinos, Georgios Iatrakis, Stefanos Zervoudis, Nikolaos Nikolettos, Panagiotis Tsikouras
{"title":"The Comparative Study of the Administration of the Combination Preparation of Isoflavones and Hyaluronic Acid in Menopausal Women for the Treatment of the Symptoms of Menopause, Urogenital Atrophy and Oteoporosis in Relation to Existing Hormone Replacement Therapies.","authors":"Anna Chalkidou,&nbsp;Efthimios Oikonomou,&nbsp;Dimitrios Lambrinos,&nbsp;Anastasia Bothou,&nbsp;Dimitrios Kyriakou,&nbsp;Konstantinos Nikolettos,&nbsp;Georgios Marinos,&nbsp;Georgios Iatrakis,&nbsp;Stefanos Zervoudis,&nbsp;Nikolaos Nikolettos,&nbsp;Panagiotis Tsikouras","doi":"10.5455/msm.2023.35.206-214","DOIUrl":"10.5455/msm.2023.35.206-214","url":null,"abstract":"<p><strong>Background: </strong>Menopause is characterized by a series of symptoms and effects from the various systems and organs, for which, the decline in estrogen production from the ovaries is considered responsible.</p><p><strong>Objective: </strong>The aim of this study was to make comparative study of the administration of the combination preparation of isoflavones and hyaluronic acid in menopausal women for the treatment of the symptoms of menopause, urogenital atrophy and osteoporosis in relation to existing hormone replacement therapies.</p><p><strong>Methods: </strong>In this five-year, double-blind, placebo-controlled clinical study, a total of 274 postmenopausal women were enrolled and classified into three groups. Participants in group A, were 96 women who did not receive Hormone Replacement Therapy (HRT), in the second group, 92 received daily treatment with tibolone (2.5 mg) as monotherapy, and in the third group, 86 received treatment with a pharmaceutical formulation of hyaluronic acid 120 mg and isoflavones. MF11RCE 80 mg.</p><p><strong>Results: </strong>In the postmenopausal women of our study, a significant reduction of postmenopausal symptoms was found in both groups B and C of participants who received hormone replacement preparations compared to group A who did not receive HRT. Furthermore, no difference in efficacy was observed between the administered preparations of isoflavones and tibolone.</p><p><strong>Conclusion: </strong>The combination of isoflavones and hyaluronic acid has the same efficacy as tibolone in menopausal symptoms.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"206-214"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/43/MSM-35-206.PMC10545921.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41176495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Study of the Correlation Between Twin Pregnancies and Perinatal Outcome in Association to the Impact of Preterm Birth. 双胎妊娠和围产期结果与早产影响的相关性的回顾性研究。
Materia socio-medica Pub Date : 2023-09-01 DOI: 10.5455/msm.2023.35.215-221
Spyridon Michalopoulos, Panagiotis Tsikouras, Vassiliki Varlami, Dimitrios Lambrinos, Anastasia Bothou, Konstantinos Nikolettos, Stavroula Papanikolopoulou, Georgios Marinos, Georgios Iatrakis, Nikolaos Nikolettos
{"title":"Retrospective Study of the Correlation Between Twin Pregnancies and Perinatal Outcome in Association to the Impact of Preterm Birth.","authors":"Spyridon Michalopoulos,&nbsp;Panagiotis Tsikouras,&nbsp;Vassiliki Varlami,&nbsp;Dimitrios Lambrinos,&nbsp;Anastasia Bothou,&nbsp;Konstantinos Nikolettos,&nbsp;Stavroula Papanikolopoulou,&nbsp;Georgios Marinos,&nbsp;Georgios Iatrakis,&nbsp;Nikolaos Nikolettos","doi":"10.5455/msm.2023.35.215-221","DOIUrl":"10.5455/msm.2023.35.215-221","url":null,"abstract":"<p><strong>Background: </strong>Twin pregnancies make up 2% to 4% of all births. Incidence of spontaneous twin pregnancies varies around the world, with percentages ranging from 8/1000 to >17/1000 births. The variation in twin pregnancy rates is thought to be due to dizygotic pregnancies, since monozygotic pregnancies have a consistent incidence of 3.5/1000 to 4/1000 births. The incidence of twin pregnancies after the widespread use of assisted reproduction has increased significantly.</p><p><strong>Objective: </strong>The purpose of the present study is to investigate factors , who contribute to improve the perinatal outcome in twin pregnancies. Support will be provided by the results of twin pregnancies by the Department of Obstetrics and Gynaecology of Demokrition University of Thrace (Alexandroupolis, Greece) in the last fifteen years.</p><p><strong>Methods: </strong>From the above Department, data were collected on the number of twin pregnancies, maternal age, gestational age, mode of delivery (spontaneous delivery or caesarean section), birth weight and rate of twin pregnancies with assisted reproduction.</p><p><strong>Results: </strong>The results showed the increasing trend of twin pregnancies and births. A total of 304 twin pregnancies were identified (rate 2.75%). The rate of assisted reproduction was 34.83% in our sample, while the rate of cesarean deliveries was 95.5%, showing a large increase in recent years. In ten cases, normal delivery was successfully performed. The gestational age in twin pregnancies that ended with normal delivery was 37.37 + 3 weeks and the fetuses were both cephalic presentations. The main reason for admission of newborns to the NICU Department was prematurity.</p><p><strong>Conclusion: </strong>The constantly improving education of perinatalists and understanding of the pathophysiology may lead to individualization of their treatment, and improvement of their prognosis based on recent scientific data from other international centers.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"215-221"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/1b/MSM-35-215.PMC10545924.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and Attitudes in First Aid Practices for Thermal Burns: a Cross-sectional Study Among Adults in Northern Greece. 热烧伤急救实践中的知识和态度:希腊北部成年人的横断面研究。
Materia socio-medica Pub Date : 2023-09-01 DOI: 10.5455/msm.2023.35.228-233
Vasiliki Papachristodoulou, Gregory Tripsianis, Theodoros C Constantinidis, Despoina D Kakagia
{"title":"Knowledge and Attitudes in First Aid Practices for Thermal Burns: a Cross-sectional Study Among Adults in Northern Greece.","authors":"Vasiliki Papachristodoulou,&nbsp;Gregory Tripsianis,&nbsp;Theodoros C Constantinidis,&nbsp;Despoina D Kakagia","doi":"10.5455/msm.2023.35.228-233","DOIUrl":"10.5455/msm.2023.35.228-233","url":null,"abstract":"<p><strong>Background: </strong>Burns are a major cause of morbidity, including prolonged hospitalization, disfigurement, disability, and emotional trauma. Long-term absence from work and high healthcare costs for burn treatment have a significant socio-economic impact.</p><p><strong>Objective: </strong>his study aims to evaluate the level of knowledge for burn management in the adult population of Thrace in Northern Greece and to determine factors associated with a better level of knowledge.</p><p><strong>Methods: </strong>A questionnaire-based cross-sectional study was conducted οn a random sample of the adult population of Thrace. Data were collected using a structured pre-coded questionnaire, which included subjects' socio-demographic characteristics and the first aid practices for burns. Multivariate logistic regression analysis was used to determine the effect of subjects' characteristics on their knowledge of burn first aid practices.</p><p><strong>Results: </strong>A total of 711 subjects (49.6% males; mean age, 41.89±16.48 years) were included in the study. The incidence of a previous burn was 55.4%. Only 10.5% of the subjects would apply the optimal practice, consisting of rinsing the burn wound with cool running water for at least 10 minutes, applying only non-adhesive dressing on it and leaving the blisters intact. The optimal practice was independently associated with female gender (aOR=1.86, p=0.016), high education level (aOR=2.00, p=0.023), the presence of >3 children (aOR=2.27, p=0.009) and previous training in first aid (aOR=2.36, p=0.001). A large number of participants reported the application of toothpaste (38%), moisturizer (35.4%), aloe (31.8%) or yogurt (27.7%) to the burn surface.</p><p><strong>Conclusion: </strong>Only a small proportion of the participants were aware of the optimal burn first aid practices, most of them female, of high socioeconomic status. We recommend a more targeted approach in the design of health campaigns in the future, in order to reach vulnerable parts of the population.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"228-233"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/c0/MSM-35-228.PMC10545918.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41163698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Sleeping Disorders on the Growth Parameters of Lebanese Children. 睡眠障碍对黎巴嫩儿童生长参数的影响。
Materia socio-medica Pub Date : 2023-09-01 DOI: 10.5455/msm.2023.35.201-205
Micheline Katramiz, Antoine Saadé, Mode Al Ojaimi, Mona Nahas Gholmieh
{"title":"Effect of Sleeping Disorders on the Growth Parameters of Lebanese Children.","authors":"Micheline Katramiz, Antoine Saadé, Mode Al Ojaimi, Mona Nahas Gholmieh","doi":"10.5455/msm.2023.35.201-205","DOIUrl":"10.5455/msm.2023.35.201-205","url":null,"abstract":"<p><strong>Background: </strong>Sleep is a vital physiological function for the maintenance of health and quality of life by ensuring body rest and restoring its energy levels. Remarkably, some children have sleep disordered breathing (SDB) that can disturb their normal sleep and affect the quality of their lives.</p><p><strong>Objective: </strong>The aim of this study was to assess the correlation between SDB and growth impairments and wether the growth parameters vary among genders.</p><p><strong>Methods: </strong>This study was conducted in two steps: 1500 questionnaires were distributed to children aged 3 to 12 years. The questionnaire covered personal information, medical history, and the Pediatric Sleep Questionnaire. The latter was used to evaluate the incidence of sleep-disordered breathing and was completed by parents of the involved children. Growth assessment was then determined for the population to find the correlation between sleep disorders and growth impairments.</p><p><strong>Results: </strong>A total of 931 completed questionnaires were returned (70.7% response rate). Among the respondents, 56.3% were females whereas 43.3% were males. The mean age was 8 years. The result showed that 16.11% of children were at high risk of sleep-disordered breathing. A significant effect of SDB syndrome on growth parameters (weight-for-age parameter z-score and BMI for age z-score) was observed among males. Concerning the weight for age z-score, a significant difference was found between the means of control and SDB individuals (P = 0.0302). In male groups, the difference was significant (P=0.043), while non-significant difference was found in female groups (P = 0.69).</p><p><strong>Conclusion: </strong>This study highlights a significant effect of SDB on growth parameters among males aged between 3 and 12 years.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"201-205"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/d6/MSM-35-201.PMC10545929.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41161159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 Pandemic on Perceived Social Support and Mental Health of Persons With Disabilities in Bosnia and Herzegovina. 新冠肺炎疫情对波斯尼亚和黑塞哥维那残疾人社会支持和心理健康的影响。
Materia socio-medica Pub Date : 2023-09-01 DOI: 10.5455/msm.2023.35.196-200
Senad Mehmedinovic, Midhat Causevic, Muharem Zildzic, Renata Salihovic, Benjamin Avdic, Mirza Sitarevic, Nizama Salihefendic, Samir Sinanovic
{"title":"Impact of COVID-19 Pandemic on Perceived Social Support and Mental Health of Persons With Disabilities in Bosnia and Herzegovina.","authors":"Senad Mehmedinovic,&nbsp;Midhat Causevic,&nbsp;Muharem Zildzic,&nbsp;Renata Salihovic,&nbsp;Benjamin Avdic,&nbsp;Mirza Sitarevic,&nbsp;Nizama Salihefendic,&nbsp;Samir Sinanovic","doi":"10.5455/msm.2023.35.196-200","DOIUrl":"https://doi.org/10.5455/msm.2023.35.196-200","url":null,"abstract":"<p><strong>Background: </strong>In December of 2019, SARS-CoV-2, a new type of coronavirus, appeared, and it turned into an international epidemic. The consequences of the pandemic, especially the isolation measures, fear of infection and bad economic trends, as a result of the crisis, threaten people's basic psychological needs.</p><p><strong>Objective: </strong>The objective of this research was to assess the impact of the COVID-19 pandemic on mental health and perceived social support of persons with disabilities in Bosnia and Herzegovina.</p><p><strong>Methods: </strong>The research included a total sample of 232 respondents with different types of disabilities. The Symptom Checklist (SCL-90) was used to verify the research objective, which assessed three dimensions: somatization, depression and anxiety. Also, in order to verify the research objective, the Multidimensional Scale of Perceived Social Support was applied, which consists of 12 statements that measure the perceived social support of family, friends and other people. The research data was processed with descriptive and inferential statistics. The basic statistical parameters were calculated, while the t-test was used for an independent sample of respondents to verify the set objective.</p><p><strong>Results: </strong>The results of the research showed that persons with disabilities, who were infected with the SARS-Cov-2 virus, had a significantly higher level of somatization, anxiety and depression compared to those who were not infected with the virus. The results in relation to social support did not prove to be statistically significant.</p><p><strong>Conclusion: </strong>The obtained results lead to the conclusion that, in the future, interventions by experts of various profiles must be planned to preserve the mental health of persons with disabilities, which is why it is important to invest in the emotional, psychological, social, physical and spiritual well-being of the individual.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/ec/MSM-35-196.PMC10545925.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Potential of Ratio Between Creatine Kinase and Amylase in Acute Pancreatitis. 急性胰腺炎患者肌酸激酶与淀粉酶比值的诊断潜力
Materia socio-medica Pub Date : 2023-01-01 DOI: 10.5455/msm.2023.35.280-284
Azra Husic-Selimovic, Rijad Jahic, Avdo Kurtovic, Nerma Custovic, Almir Fajkic
{"title":"Diagnostic Potential of Ratio Between Creatine Kinase and Amylase in Acute Pancreatitis.","authors":"Azra Husic-Selimovic, Rijad Jahic, Avdo Kurtovic, Nerma Custovic, Almir Fajkic","doi":"10.5455/msm.2023.35.280-284","DOIUrl":"10.5455/msm.2023.35.280-284","url":null,"abstract":"<p><strong>Background: </strong>Acute pancreatitis (AP) is an acute inflammatory illness of the pancreas representing a true question in diagnostic process. Laboratory markers of the hepatobiliary tract such as liver transaminases with pancreatic enzymes give a true hint of a hidden diagnosis together with urea, creatinine and creatine kinase (CK).</p><p><strong>Objective: </strong>This clinical study aims to show whether there is any correlation between alpha-amylase and CK or their ratio examining hospitalized patients with AP diagnosis.</p><p><strong>Methods: </strong>From total number of 99 patients with a clinical picture of AP, 71 patients in this retrospective analysis (including both genders) were included according to the presence of two biochemical markers in collected laboratory analysis at admission and 72 hours later on a laboratory check-up: CK and alpha-amylase.</p><p><strong>Results: </strong>The median CK value of AP cases was 92 (41.75 - 207.25) in the acute period and 73 (37 - 159) after 72h staying in the hospital without statistical significant (p=0.521; p<0.05). However, there was a statistically significant correlation between the parameters of CK at admission and creatine kinase after 72h staying in the hospital. The median value of CK/Amylase ratio in the acute period was 0.168 (0.069 - 0.532) and 0.386 (0.12 - 1.12) after 72 hours of staying in the hospital. There was a statistically significant difference between values of CK/amylase ratio in these two groups (p=0.000; p<0.01).</p><p><strong>Conclusion: </strong>In conclusion, a connection between CK and alpha-amylase needs to be elucidated in further studies and its existence must be researched both in physiological and pathophysiological conditions, and it is two-way and very complex. This study helped us obtain significant information about the perspective of AP in the potential relation to other non-standard laboratory markers for some diseases.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 4","pages":"280-284"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Coagulation Markers to Evaluate the Effectiveness of Coronavirus Disease (COVID-19) Therapeutic Protocols. 使用凝血标志物评估冠状病毒病 (COVID-19) 治疗方案的效果。
Materia socio-medica Pub Date : 2023-01-01 DOI: 10.5455/msm.2023.35.270-274
Naida Omerovic, Tamer Bego, Besim Prnjavorac, Nermina Ziga Smajic, Fahir Becic, Halil Corovic, Selma Skrbo
{"title":"The Use of Coagulation Markers to Evaluate the Effectiveness of Coronavirus Disease (COVID-19) Therapeutic Protocols.","authors":"Naida Omerovic, Tamer Bego, Besim Prnjavorac, Nermina Ziga Smajic, Fahir Becic, Halil Corovic, Selma Skrbo","doi":"10.5455/msm.2023.35.270-274","DOIUrl":"10.5455/msm.2023.35.270-274","url":null,"abstract":"<p><strong>Background: </strong>Patients infected by coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), display various symptoms and severity of the clinical picture. Thus, the therapy and pathophysiology of this disease are a dilemma for health professionals and scientists.</p><p><strong>Objective: </strong>This paper aims to evaluate the effectiveness of therapeutic protocols (the use of anticoagulants) in the treatment of COVID-19 patients of various severity of the clinical picture by monitoring coagulation markers (PT, INR, aPTT and D-dimer), as well as the impact of the type and number of comorbidities patients had on these markers.</p><p><strong>Methods: </strong>A total of 200 patients with a mild (n=76), moderate (n=70) or severe (n=54) clinical picture was included. Coagulation markers [PT (prothrombin time), INR (international normalized ratio), aPTT (activated partial thromboplastin time), D-dimer] were examined on three occasions: twice during hospitalization and once after hospital discharge. Anticoagulants used intrahospital were fraxiparine, rivaroxaban or unfractionated heparin. Posthospital, patients were taking either rivaroxaban or did not use any anticoagulants. For statistical analysis, SPSS 26.0 and Microsoft Excel 2019 were used, with a level of significance of α=0.05. Nonparametric tests (Kruskal-Wallis, Wilcoxon Signed-Rank and Bonferroni) were applied and effect size (ES) was calculated.</p><p><strong>Results: </strong>Three anticoagulants used intrahospital caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture, but the ES was the biggest with fraxiparine, then rivaroxaban, and lastly unfractionated heparin. Posthospital, rivaroxaban caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture. Hypertension was the most common comorbidity in all patients, as well as in patients with a severe clinical picture. There was a statistically significant impact of the number of comorbidities patients had on D-dimer, and none on PT, INR and aPTT, but the highest number of comorbidities was in patients with a severe clinical picture.</p><p><strong>Conclusion: </strong>The use of anticoagulants, especially fraxiparine intrahospital and rivaroxaban posthospital, is justified in most COVID-19 cases as there is a significant correlation between this disease's pathophysiology and the coagulation process. There is also a positive correlation between the severity of the clinical picture and the number of comorbidities patients have.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 4","pages":"270-274"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Kidney Injury Classifications in the Prediction of In-hospital Mortality and Renal Function Non-recovery. 急性肾损伤分类在预测院内死亡率和肾功能未恢复中的应用
Materia socio-medica Pub Date : 2023-01-01 DOI: 10.5455/msm.2023.35.304-308
Aida Hamzic-Mehmedbasic, Melina Mackic, Damir Rebic, Hajrudin Spahovic, Ajla Arnautovic-Halimic, Nadina Jakirlic
{"title":"Acute Kidney Injury Classifications in the Prediction of In-hospital Mortality and Renal Function Non-recovery.","authors":"Aida Hamzic-Mehmedbasic, Melina Mackic, Damir Rebic, Hajrudin Spahovic, Ajla Arnautovic-Halimic, Nadina Jakirlic","doi":"10.5455/msm.2023.35.304-308","DOIUrl":"10.5455/msm.2023.35.304-308","url":null,"abstract":"<p><strong>Background: </strong>In the last two decades diagnostic criteria for acute kidney injury (AKI) were developed: Risk, Injury, Failure, Loss of Kidney Function, End-Stage Kidney Disease (RIFLE), Acute Kidney Injury Network (AKIN), and Kidney Disease: Improving Global Outcomes (KDIGO) classifications.</p><p><strong>Objective: </strong>The study aimed to determine the incidence of AKI based on the RIFLE, AKIN, and KDIGO criteria, as well as analyze their predictive value for mortality and renal function outcome.</p><p><strong>Methods: </strong>This was a single-center prospective study of patients diagnosed with AKI. Acute kidney injury was defined and classified according to the RIFLE, AKIN, and KDIGO criteria. The outcomes were renal function outcome and in-hospital mortality.</p><p><strong>Results: </strong>The incidence rates of AKI based on the RIFLE, AKIN, and KDIGO criteria were 13.4%, 14-36%, and 14.64%, respectively. Multiple regression analysis showed that higher stages of AKI according to the KDIGO criteria were independently associated with non-recovery of renal function (p=0.011). However, the predictive ability of RIFLE, AKIN and KDIGO classifications for renal function recovery was poor (Area Under the Receiver Operating Characteristics-AUROC=0.599, AUROC=0.637, AUROC=0.659, respectively). According to the RIFLE and AKIN criteria, in-hospital mortality was statistically significantly higher in stage Failure/3 (p=0.0403 and p=0.0329, respectively) compared to stages Risk/1 and Injury/2. Receiver Operating Characteristics (ROC) analysis showed that all three classifications had poor predictive ability for in-hospital mortality (AUROC=0.675, AUROC=0.66, AUROC=0.681).</p><p><strong>Conclusions: </strong>KDIGO classification is an independent predictor of renal function non-recovery. However, by ROC analysis, all three classifications have poor predictive ability for renal function outcome and mortality.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 4","pages":"304-308"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Birth Experience and Breastfeeding Ineffectiveness - a Literature Review. 创伤性分娩经历与母乳喂养无效--文献综述。
Materia socio-medica Pub Date : 2023-01-01 DOI: 10.5455/msm.2023.35.325-333
Maria Tzitiridou-Chatzopoulou, Eirini Orovou, Rafailia Skoura, Panagiotis Eskitzis, Maria Dagla, Maria Iliadou, Ermioni Palaska, Evangelia Antoniou
{"title":"Traumatic Birth Experience and Breastfeeding Ineffectiveness - a Literature Review.","authors":"Maria Tzitiridou-Chatzopoulou, Eirini Orovou, Rafailia Skoura, Panagiotis Eskitzis, Maria Dagla, Maria Iliadou, Ermioni Palaska, Evangelia Antoniou","doi":"10.5455/msm.2023.35.325-333","DOIUrl":"10.5455/msm.2023.35.325-333","url":null,"abstract":"<p><strong>Background: </strong>A traumatic birth experience can affect the breastfeeding process and make it ineffective. The aim of this study was to identify the factors associated with breastfeeding ineffectiveness after birth trauma, through the world literature. There are several factors responsible for a traumatic birth experience, such as obstetric violence, postpartum complications and complications induced by doctors, invasive vaginal deliveries, emergency caesarean sections, admission of a neonate to the Neonatal Intensive Unit, past traumatic life events and mental health problems.</p><p><strong>Objective: </strong>The aim of this study was to identify the factors associated with breastfeeding ineffectiveness after birth trauma, through the world literature.</p><p><strong>Methods: </strong>An extended search was conducted to identify relevant for breastfeeding and traumatic birth experiences manuscripts for this study. Databases including PubMed, PsycINFO and Google Scholar. The search was limited to articles published in English the last decade.</p><p><strong>Results: </strong>Factors that contribute to the ineffectiveness of breastfeeding after a traumatic birth are hormonal, medication, insufficient support from the partner, reliving the traumatic birth experience, past traumatic experiences in the woman's life and her mental state.</p><p><strong>Conclusion: </strong>The mental trauma during childbirth is complex and multifactorial. Therefore, it is necessary to take measures on the one hand to prevent mental trauma during childbirth and on the other hand to make interventions to deal with the consequences of the trauma on the mental health of the mother and on breastfeeding which is directly affected.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 4","pages":"325-333"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Echocardiographic Findings of Covid-19 Patients in Canton Sarajevo During the Third Wave of the Covid-19 Pandemic. 第三波 Covid-19 大流行期间萨拉热窝州 Covid-19 患者的超声心动图检查结果。
Materia socio-medica Pub Date : 2023-01-01 DOI: 10.5455/msm.2023.35.290-294
Armin Sljivo, Lejla Brigic, Arian Abdulkhaliq, Ilma Dadic, Leopold Reiter, Iman Sirucic, Mohammed Abdulkadir, Ahmed Mulac
{"title":"Echocardiographic Findings of Covid-19 Patients in Canton Sarajevo During the Third Wave of the Covid-19 Pandemic.","authors":"Armin Sljivo, Lejla Brigic, Arian Abdulkhaliq, Ilma Dadic, Leopold Reiter, Iman Sirucic, Mohammed Abdulkadir, Ahmed Mulac","doi":"10.5455/msm.2023.35.290-294","DOIUrl":"10.5455/msm.2023.35.290-294","url":null,"abstract":"<p><strong>Background: </strong>Increasing evidence indicates that COVID-19 may result in cardiac issues in certain individuals, such as myocarditis, arrhythmias, and heart failure. Ongoing research on echocardiographic manifestations is still limited.</p><p><strong>Objective: </strong>To investigate the incidence and patterns of left and right ventricular dysfunction in COVID-19 patients.</p><p><strong>Methods: </strong>This study retrospectively observed COVID-19 patients admitted to the Clinical Center of University of Sarajevo during the third wave, with a particular focus on cardiac evaluations.</p><p><strong>Results: </strong>Our patients, predominantely male 155 (72.4%), with a mean age of 66.2±11.4, having hypertension 86 (40.1%), diabetes mellitus 61 (28.5%), hyperlipidemia 144 (67.3%), were active smokers 87 (40.6%), had family history of cardiovascular diseases 123 (57.5%) and were COVID-19 positive 95 (44.4%), presented because of chest pain 78 (36.4%), dyspnea 103 (48.1%), palpitations 67 (31.3%), fatigue 106 (49.5%) and peripheral oedema 30 (14.0%). COVID-19 patients reported much higher symptoms of dyspnea (65 (68.4%) vs 38 (31.9%)) and fatigue (73 (76.8%) vs 33 (27.7%)) than COVID-19 negative patients. On the initial laboratory report, COVID-19 patients had a significantly (p<0.05) higher mean score of C-reactive protein (24.0±4.8 vs. 6.0±2.1), D-dimer (1.6±2.5 vs 0.8±0.6), ALT (94.8±17.2 vs 36.5±19.9) and creatinine (128.0±80.8 vs. 93.4±40.1) when compared to COVID-19 negative patients. COVID-19 patients had enlarged left atrium diametes (31.6±5.6 vs 27.5±5.3), enlarged left ventricular diameter both in systole (27.9±18.1 vs 23.3±16.3) and diastole (39.3±24.1 vs 34.9±22.7), reduced left ventricular ejection fraction (53.5±9.2 vs 59.8±4.3) and elevated right ventricular systolic pressure (37.0±16.4 vs 35.1±8.6).</p><p><strong>Conclusion: </strong>COVID-19 patients had enlarged left atrium, enlarged systolic and diastolic left ventricular diameter, reduced left ventricular ejection fraction and elevated right ventricular systolic pressure.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 4","pages":"290-294"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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