Materia socio-medica最新文献

{"title":"Efficacy and Safety of Lysozyme, Cetylpyridinium and Lidocaine Fixed Combination for Treatment of Chemotherapy- and Radiotherapy-Induced Oral Mucositis: a Pilot Study","authors":"Azra Rašić, Belma Kapo, Asmir Avdičević, Alma Mekić Abazović, S. Janković, Aida Lokvančić","doi":"10.5455/msm.2019.31.166-171","DOIUrl":"https://doi.org/10.5455/msm.2019.31.166-171","url":null,"abstract":"Introduction: Beneficial effect of local administration of lysozyme in patients with recurrent aphthous stomatitis was demonstrated, but there are no published studies focused on treatment of chemotherapy or radiotherapy induced oral mucositis with lysozyme. Aim: The aim of this study was to compare efficacy and safety of Lysobact Complete spray (lysozyme, cetylpyridinium, and lidocaine) and compounded medication for local use in the treatment of radio- and chemo-therapy induced oral mucositis. Patients and Methods: This observational, phase IV study was designed as prospective cohort investigation, and conducted at two sites, Clinical Hospital Zenica and University Clinical Center Tuzla, Bosnia & Herzegovina, from August to November, 2018. The patients with oral mucositis after radio- or chemo-therapy were treated by either registered lysozyme-based or compounded medication (standardized and bicarbonate-based) for 21 days. Results: Both lysozyme-based (Lysobact Complete Spray) spray (lysozyme, cetylpyridinium and lidocaine) and compounded medication for local use were effective in local treatment of chemotherapy and radiotherapy-induced oral mucositis. However, lysozyme-based preparation was more effective, since signs of inflammation, number of oral ulcers and intensity of pain during eating and speaking withdrew to a greater extent than with highly variable compounded medication for local use. No adverse events were recorded in both treatment arms. Conclusions: Locally administered spray with fixed combination of lysozyme, cetylpyridinium and lidocaine (Lysobact Complete Spray) is very efficient and completely safe treatment of both radiotherapy and chemotherapy-induced oral mucositis.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"166 - 171"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46867324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Dissection of the Coronary Vessels. Epidemiological and Coronary Angiographic Study","authors":"I. Vogiatzis, E. Sdogkos, Andreas Aidinis, Kariofillis Kousidis, Pavlos Roditis, Anila Spahiou, Maria Pliatsika, S. Pittas","doi":"10.5455/msm.2019.31.177-180","DOIUrl":"https://doi.org/10.5455/msm.2019.31.177-180","url":null,"abstract":"Introduction: Spontaneous dissection of the coronary arteries is relatively rare and usually does not affect life expectancy. However specific types have been implicated to episodes of sudden cardiac death and myocardial ischemia. The recognition of both clinical and imaging characteristics contributes to appropriate decision and patient management. Aim: The aim of the study is the epidemiological and Coronary Angiographic (CA) estimation of patients with spontaneous dissection of the coronary arteries, who were hospitalized in the cardiology department with Acute Coronary Syndrome or were submitted to coronary angiographic examination in the laboratory. Material and Methods: The epidemiological, clinical and angiographic data of 31 patients who were hospitalized in our department and suffered from spontaneous dissection of the coronary vessels were studied retrospectively. Results: In 31 patients (11 men and 20 women, mean age 52.8+18.6 years) who were hospitalized for acute coronary syndrome (ACS), spontaneous dissection of coronary arteries was detected. Precipitating factors were hypertension in 12 patients (38.71%), dyslipidemia in 13 patients (42%) and smoking in 17 patients (54.84%). Among the women, 13 (65%) had a history of hypertension in pregnancy, preeclampsia or/and gestational diabetes. In 8 patients, the coronary angiography showed multivessel disease, while in 12 patients there were no significant lesions in the coronary vessels. Fourteen women (70%) reported a history of depression compared to none in men. Conclusion: The incidence of spontaneous dissection of the coronary vessels in this sample of patients from northern Greece is similar to that of the other centers. The incidence is greater in females with hormonal changes and depression. In a large number there were no significant atherosclerotic lesions.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"177 - 180"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42630100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minor Head Trauma and its Short-term Outcomes Among Elderly Patients: a Prospective Epidemiological Study in North of Iran","authors":"S. M. Hosseininejad, Fatemeh Jahanian, Iraj Goli-Khatir, A. Alaee, Seyedeh Mahsa Taghian","doi":"10.5455/msm.2019.31.186-189","DOIUrl":"https://doi.org/10.5455/msm.2019.31.186-189","url":null,"abstract":"Introduction: Traumatic brain injury (TBI) is of the most challenging public health problems. Aim: The aim of this study was to investigate the epidemiology of mild TBI, frequency of clinically important head injuries identifiable on computed tomography (CT) scans and also short-time outcomes of mild TBI in elderly population in north of Iran. Patients and Methods: A prospective epidemiological study was conducted at the Emergency department of Imam Khomeini general hospital, Mazandaran, Iran. Inclusion criteria were age older than 60, Glasgow coma scale (GCS) score of 13-15, and a single head trauma. Data were collected by retrospective chart review, interview with patients or their caregivers and contact with them after a week from time of discharge or transferring to another wards. Results: Response rate was estimated at 67.8% (n: 122/180). Mean age of patients was 65.54±6.42 years. 82% of patients were younger than 70. Mean time from head trauma to hospital admission was 270 minutes. In majority of patients, mechanism of trauma was fall (28%) and then interpersonal violence (25%). 6.6% (95% CI: 2.87 to 12.5%) of patients suffered from important radiologically head injuries and 2.5% (95% CI: 0.5-7.00) were readmitted to hospital within a week. Conclusion: Time to admission for minor TBI in elderly patients was too long and could be of clinical concern. Considering the lower prevalence of important radiologically head injury among elderly population, using any clinical guideline for indication of CT scan may be more cost-effective than routine use of CT scan. Although short term outcomes of minor TBI were less threatening and not lethal but these patients need follow-up.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"186 - 189"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44770810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccination Coverage and Awareness of Hepatitis B Virus Among Healthcare Students at a University in Cyprus","authors":"Z. Roupa, M. Noula, E. Farazi, A. Stylianides, C. Papaneophytou","doi":"10.5455/msm.2019.31.190-196","DOIUrl":"https://doi.org/10.5455/msm.2019.31.190-196","url":null,"abstract":"Introduction: The risk for healthcare students to get infected by transmitting infectious viruses, including hepatitis B virus (HBV), in a hospital setting is extremely high through exposure to blood and/or body secretions. Aim: The aim of this work was to evaluate both the vaccination history of healthcare students at a University in Cyprus and their serologic immunity against HBV. In addition, we assessed their knowledge and behaviors towards the transmission and prevention of hepatitis B (HB). Results: Total amount of 168 students participated in this study and more than 50% of them provided complete documentation of vaccination history against HBV. Antibodies levels ×10 mIU/mL to HB surface antigen (HBsAg) were detected for the 98.8% of healthcare students while 1.2% of the participants tested positive for HBsAg and antibodies to HB core antigen indicating chronic infection. Our study also revealed significant gaps in the knowledge of healthcare students on the efficiency of the vaccine against HBV and in terms of the HBV transmission. Conclusions: More information needs to be provided to healthcare students in Cyprus regarding HBV transmission and vaccination. In addition, there is a need for intervention to provide a safer workplace environment.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"190 - 196"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46339619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Compassion Fatigue, Burn-Out and Compassion Satisfaction Among Maternity and Gynecology Care Providers in Greece","authors":"Kalliopi Katsantoni, A. Zartaloudi, D. Papageorgiou, M. Drakopoulou, Evdokia Misouridou","doi":"10.5455/msm.2019.31.172-176","DOIUrl":"https://doi.org/10.5455/msm.2019.31.172-176","url":null,"abstract":"Introduction: Maternity and gynecology professionals are exposed to distressing events, trauma and suffering that may trigger compassion fatigue. Aim: The aim of this study was to investigate the prevalence of compassion fatigue/secondary traumatic stress (CF/STS), burnout (BO) and compassion satisfaction (CS) in maternity and gynecology care providers. Material and Methods: The Professional Quality of Life Scale (ProQOL R-IV) and a demographic and work-related characteristics questionnaire were distributed to 121 certified nurses, midwives and nurse/midwife assistants in 3 public hospitals in Greece. Results: The majority of participants were at the high-risk category for CF/STS (73.9%) while only 19.8% and 5% of nurses expressed high potential for CS and BO, respectively. Awareness of the factors associated with CF may help nurses to prevent or offset the development of this condition. Conclusion: A compassionate organizational culture, clinical supervision and on-going education may protect care providers from absorbing or internalizing unmanageable emotions which may lead to compassion fatigue and also help them to gain a deeper understanding of their communication and interactions during the emotionally laden moments of maternity and gynecology care.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"172 - 176"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45007461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence- based Management Options for Nonspecific Musculoskeletal Pain in Schoolchildren","authors":"N. Pranjić, Selma Azabagić","doi":"10.5455/msm.2019.31.215-218","DOIUrl":"https://doi.org/10.5455/msm.2019.31.215-218","url":null,"abstract":"Introduction: Children of school age (8-15 years) have a significant prevalence of non-specific musculoskeletal pain (from 11 to 38%, in our country as much as 48%), which represents a neglected public health problem without adequate preventive interventions. Health workers have little empirical evidence to support their clinical practice in deciding on intervention measures and treating this pain. Aim: The aim of this review article is to expand knowledge of the management of nonspecific musculoskeletal pain in school children based on the evidence. Material and Methods: The systematic review of literature was carried out at Biomed Central, PubMed, Scopus and Web of Science databases in search of relevant evidence supporting the research goal. Results: A total of 564 publications were reviewed and 523 were considered irrelevant. The remaining 47 publications were assessed as potentially relevant, and among them 39 did not meet the criteria for inclusion and exclusion. Therefore, 9 publications met the necessary criteria for further analysis. Conclusion: There is little evidence to create an integrative program of intervention measures and treatment of musculoskeletal pain in school children. Based on scarce number of proofs shown in this research, no conclusive solutions have been reached, necessitating a need for further research.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"215 - 218"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45727944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fecal and Urinary Incontinence Associated with Pregnancy and Childbirth","authors":"A. Subki, M. M. Fakeeh, M. Hindi, A. Nasr, Adel Almaymuni, H. Abduljabbar","doi":"10.5455/msm.2019.31.202-206","DOIUrl":"https://doi.org/10.5455/msm.2019.31.202-206","url":null,"abstract":"Introduction: Fecal incontinence (FI) and urinary incontinence (UI) are major problems faced by women worldwide, with pregnancy and delivery representing two major risk factors for these conditions. The prevalence of FI and UI varies across studies. In our region, only a few publications have addressed this topic. Aim: The aim of this study was to determine the prevalence of FI and UI in Saudi pregnant women, their characteristics, and a specific clinical pattern that could identify patients that are at a risk for incontinence. Materials and Methods: This was a questionnaire-based crosssectional study conducted over a 3 months period in 2017, among pregnant women attending King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Results: Our study included 393 pregnant women. FI was reported by 24 patients (6.1%), and fecal urgency was reported by 30.5%. UI was reported by 84 patients (21.4 %). When patients with no UI were compared with patients with UI, the only statistically significant factor was BMI (p = 0.043). There were no statistically significant differences when comparing patients with FI versus no-FI, and fecal urgency versus no-fecal urgency. However, laceration (OR: 1.696, p = 0.036), episiotomy (OR: 1.413, p = 0.029), constipation (OR: 1.944, p < 0.001), hypertension (OR: 1.993, p = 0.022), and Bristol stool scale score (p = 0.002) were statistically significant factors for determining fecal control. Conclusion: FI and UI are frequently associated with pregnancy and delivery, but their prevalence is underestimated. The role of the practitioner is crucial in preventing and treating these conditions, and in impeding their harmful effects on the postpregnancy quality of life of Saudi women.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"202 - 206"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42566187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryotherapy of Genital Warts","authors":"Mahira Jahić","doi":"10.5455/msm.2019.31.212-214","DOIUrl":"https://doi.org/10.5455/msm.2019.31.212-214","url":null,"abstract":"Introduction: Genital warts are a frequent form of sexually transmitted disease. Cryotherapy represents the first line of therapy. Healing occurs in 94%, and recurrence in 10% . Side effects are common during the treatment. Aim: The aim of this study is to determine the successfulness of cryotherapy of genital warts, frequency of recurrence, and side effects. Patients and methods: In a retrospective study, data from 50 women with genital warts who were treated in the Gynecological Centre “Dr Mahira Jahić” in Tuzla in a period from 2012–2018 were analyzed. Every woman was treated with cryotherapy. Treatments were repeated every 7 days, maximal number of treatments being 7. In processing of data, X2statistical method was used. Results: 50% (N-25) of genital warts eliminated after 3 treatments with cryotherapy . Genital warts are eliminated in 78% (N-39) of women, while this treatment was unsuccessful in 18% (N-9). Recurrence after 3 months in 4% (N-2). Most common side effect was exudation in 78% (N-39), swelling in 72% (N-36) and pain in 66% (N-33). PAP smears in women with genital warts in 64% (N-34) of cases were inflammatory benign changes, while in 36% (N-18) mild abnormal changes in cells ASCUS and LSIL were found. LSIL lesions of cervix are more common (p<0,01) in women with genital warts of vulva. Conclusion: Cryotherapy is a method with a high success rate in healing of genital warts, and it decreases the concentration of HPV virus and removes the trigger that allows the development of cancer.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"212 - 214"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49302693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Most Influential Scientists in the Development of Public Health (3): Nikolai Aleksandrovich Semashko (1874-1949)","authors":"I. Masic","doi":"10.5455/msm.2019.31.222-223","DOIUrl":"https://doi.org/10.5455/msm.2019.31.222-223","url":null,"abstract":"","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"222 - 223"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46462656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Saudi Medical Student’s Decision Towards Cardiothoracic Surgery as a Future Career, a Cross Sectional Study","authors":"M. Algethami, Sara T. Bandah, Maha A. Safhi, Gaida A. Noman, Abdullah H. Ghunaim, Hisham A Rizk, Hani A. Alnajjar","doi":"10.5455/msm.2019.31.197-201","DOIUrl":"https://doi.org/10.5455/msm.2019.31.197-201","url":null,"abstract":"Introduction: There has been a progressive decline in students’ interest to consider cardiothoracic surgery as future career in the distant regions in the world. There are many factors could explain declining interest in cardiothoracic surgery including diminished caseloads due to the expansive growth of interventional cardiology; length of training programs that influences medical student’s perception. King Abdulaziz University student’s interest to join the speciality explored in our study. We determined some factors that influence their decision making toward their cardiothoracic career. Aim: We aimed to estimate the current interests of medical students at King Abdulaziz University to pursue a career in Cardiothoracic surgery and to determine the factors that positively or negatively affect their decision. Material and Methods: A self-administered online survey designed on Google form was distributed through email to fourth, fifth, and sixth-year medical students. Five domains; demographics, current career intentions, previous exposure to surgery, experiences and perceptions of cardiothoracic surgery were covered in the questionnaire to identify factors affecting student decision to choose cardiothoracic surgery as a future career. Results: Among 486 students at our institution, 179 (36, 83%) medical students completed the questionnaire more than half of them 91 (50.8%) were males. The percentage of students who considered cardiothoracic surgery as a future career was (4.5%); when asked if they were serious in pursuing a career in cardiothoracic surgery, (14.5%) of the student were affirmative. Of those participated in the survey, Twenty-four students believed they had adequate introduction to the cardiothoracic surgery during their undergraduate program. Conclusion: cardiothoracic surgery is falling away behind other specialties as career of choice for many future physicians. It is believed mainly related to inadequate introduction to the field. Increasing exposure and close mentorship is needed to attract more students to pursue a career in cardiothoracic surgery.","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"31 1","pages":"197 - 201"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48889874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}