Materia socio-medica最新文献

{"title":"Ultrasound-guided Femoral - Sciatic Nerve Block for Lower Limb Long Bone Fractures.","authors":"Nguyen Huu Tu, Vu Minh Hai, Nguyen The Diep, Vu Dinh Luong","doi":"10.5455/msm.2024.36.217-221","DOIUrl":"10.5455/msm.2024.36.217-221","url":null,"abstract":"<p><strong>Background: </strong>Fractures of the long bones in the lower limbs are injuries that cause severe to extremely severe pain, posing risks to the patient's circulation, respiration, and even life. Pain management for patients with lower limb long bone fractures in the emergency department is critically important.</p><p><strong>Objective: </strong>This study aimed to evaluate the feasibility of ultrasound-guided femoral and sciatic nerve blocks in patients with lower limb long bone fractures in the emergency department (ED). The secondary objective was to assess the effectiveness of this procedure as an adjunct to pain management in the ED.</p><p><strong>Methods: </strong>This observational study included 133 ED patients with lower limb long bone fractures who received ultrasound-guided femoral and sciatic nerve blocks (anterior approach). Feasibility was assessed by observing and recording procedural duration, number of attempts, and technical complexity. The effectiveness of pain management was evaluated using the visual analog scale (VAS) at the 5th, 10th, 15th, 30th, 60th, and 120th minutes. Data were gathered and analyzed using SPSS 25.0. Quantitative variables were described using frequencies and percentages, while qualitative variables were presented as mean ± standard deviation. Paired-samples T-tests were used to compare the pain scores at different time points.</p><p><strong>Results: </strong>The mean age of participants was 54.21 ± 18.43 years (range 18-93), including 76 males and 57 females. The average procedural duration was 4.92 ± 1.51 minutes (range 2.4-8.5). All blocks were successful on the first attempt, with no complications. Post-procedure, pain scores decreased by 53.47% at the 5th minute, 72.73% at the 10th minute (p < 0.001), and 97.25% at 15 minutes (p < 0.001). Pain scores remained stable from 30 to 120 minutes (p < 0.001).</p><p><strong>Conclusion: </strong>Ultrasound-guided femoral and sciatic nerve blocks (anterior approach) are feasible in the ED. This technique provides significant and sustained pain relief.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"217-221"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Thoracic Morphological Changes Using Chest CT in Patients with Congenital Pectus Carinatum Treated by the Modified Abramson Technique.","authors":"Nguyen Viet Anh, Le Thanh Dung, Ta Van Lam, Doan Vu Tu Quyen, Pham Huu Lu, Phung Duy Hong Son, Nguyen Huu Uoc, Duong Duc Hung, Doan Quoc Hung","doi":"10.5455/msm.2024.36.212-216","DOIUrl":"10.5455/msm.2024.36.212-216","url":null,"abstract":"<p><strong>Background: </strong>The Pectus carinatum is an outward protrusion deformity of the sternum and adjacent costal cartilages. It is the second most common congenital deformity of the anterior chest wall, commonly occuring in adolescents.</p><p><strong>Objective: </strong>The aim of this study was to evaluate thoracic morphological changes using computed tomography (CT) imaging in patients with pectus carinatum treated via the modified Abramson technique at Viet Duc University Hospital from 2020 to 2023.</p><p><strong>Methods: </strong>A retrospective cross-sectional study analyzed all cases of congenital pectus carinatum diagnosed, imaged via CT, and surgically treated using the modified Abramson technique at Viet Duc Hospital from January 2020 to December 2023.</p><p><strong>Results: </strong>Among 115 patients (mean age: 13.6 ± 2.03 years), the majority presented with symmetrical deformities (70.4%). The average operative duration was 33.3 ± 8.3 minutes, and hospital stays ranged from 4 to 7 days (mean: 5.2 ± 0.90 days). No major postoperative complications were reported. Follow-up ranged from 11 to 48 months. Chest CT Scan reevaluation postoperatively in 69 patients showed significant improvement in thoracic indices: mean pre- and postoperative Haller index (HI) were 2.02 ± 0.20 and 2.46 ± 0.34, respectively. Sternal rotation angle averaged 2.81 ± 3.59, with 68/69 cases showing no or mild torsion. Postoperative asymmetry index (AI) averaged -0.014 ± 0.033.</p><p><strong>Conclusion: </strong>The modified Abramson technique provides a minimally invasive and effective treatment for pectus carinatum, achieving significant improvements in thoracic morphology as evidenced by Haller index, asymmetry index, and sternal rotation angles assessed on chest CT.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"212-216"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions and Experiences of Surgical Nurses in Using the WHO Checklist in a Perioperative Setting: a Mixed-method Study.","authors":"Nail Seffo, Svemir Custovic, Jasmin Alic, Ferid Krupic","doi":"10.5455/msm.2024.36.229-235","DOIUrl":"10.5455/msm.2024.36.229-235","url":null,"abstract":"<p><strong>Background: </strong>As a surgical nurse in a healthcare team, it is helpful to position the patient, depending on the nature of the procedure, and to prepare independently both the instrumentation and the site of surgery with drapes prior to the surgical procedure.</p><p><strong>Objective: </strong>To examine the experience of surgical nurses in their work with the WHO surgical checklist in Sweden.</p><p><strong>Methods: </strong>Data were collected from one hundred and ninety-six healthcare professionals, including thirty-nine surgical nurses, using a self-administered questionnaire. The Mantel-Haenszel and Pearson <i>χ</i> ² tests were used for ordered and unordered categorical variables. The qualitative data was presented in the form of the positive and negative contribution of the checklist and the text was analyzed according to Graneheim and Lundman.</p><p><strong>Results: </strong>Surgical nurses (61.6%) answered \"no\" to the question about being educated and trained in using checklists. Almost the same answer was given when it came to adapting the checklist to the department and the fact that the assistant nurse was responsible for ensuring the checklist was used (61.5%). 89.9% of them did not know who was responsible for implementing the checklist before surgery. According to (56.4%), the checklist was used all the time in emergencies, while (12.8%) of them stated that they did not believe that the checklist improved patient safety.</p><p><strong>Conclusions: </strong>Compliance with the WHO's checklist varies, and the observed compliance is lower than that documented. The surgical nurses gave the same responses as others in the team. Clearer procedures are needed during surgery, specifying how the checklist should be used in practice, and there should be a designated person who is responsible for implementing the checklist.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"229-235"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview of the Head and Neck Hemangiomas: a 5-year Retrospective Study.","authors":"Vladimir Filaj,&nbsp;Ina Kola,&nbsp;Ferdiola Gjonaj","doi":"10.5455/msm.2023.35.244-247","DOIUrl":"10.5455/msm.2023.35.244-247","url":null,"abstract":"<p><strong>Background: </strong>Infantile hemangiomas (IHs) are benign vascular tumors commonly observed in children. The pathogenesis of hemangiomas is complex and poorly understood. IH occur most commonly on the head and neck. There are different classification of them according to the depth, number, distribution and locations. A multidisciplinary approach is needed for the diagnosis and treatment of hemangiomas because it is easy to misdiagnose or decide on a wrong treatment in the existing single-treatment system.</p><p><strong>Objective: </strong>In this retrospective study between 2018 and 2022 we provided an overview of the hemangiomas located in the head and neck in 232 patients, and the different treatment approaches used.</p><p><strong>Results: </strong>Of the 232 patients 60.3 % were females and 38.7% males. The youngest age was 10 weeks old and the oldest age who underwent treatment was 79 years old. The most common lesion sites were the mid-cheek, the upper lip and the upper eyelid. 104 patients (53.4 %) underwent surgical intervention due to the location of the lesion, size and functional reasons. Meanwhile 128 patients (46.6 %) were observed and treated with propranolol and pulsed dye laser.</p><p><strong>Conclusion: </strong>Hemangiomas are generally benign tumors. Hemangiomas present a number of diagnostic and therapeutic challenges; thus, early diagnosis by a specialist clinic is key in preventing associated morbidity with these vascular tumors.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"244-247"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/42/MSM-35-244.PMC10545920.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41163755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status of Biological Treatment in Ankylosing Spondylitis Patients and Some Related Factors.","authors":"Bui Hai Binh,&nbsp;Nguyen Ngoc Trung,&nbsp;Nguyen-Van Hung,&nbsp;Nguyen-Thi Ngoc Yen,&nbsp;Nguyen-Thi Nhu Hoa,&nbsp;Nguyen Thanh Hiep,&nbsp;Nguyen Minh Duc,&nbsp;Le-Thi Bich Phuong","doi":"10.5455/msm.2023.35.222-227","DOIUrl":"10.5455/msm.2023.35.222-227","url":null,"abstract":"<p><strong>Background: </strong>Axial spondyloarthritis (axSpA) is a potentially disabling inflammatory arthritis of the spine, usually presenting as chronic back pain typically before the age of 45 years. It is often associated with one or more articular features, including synovitis, enthesitis, and dactylitis. It may also be associated with several non-articular features; these include uveitis, psoriasis, and inflammatory bowel diseases1.</p><p><strong>Objective: </strong>The aim of this article is to describe the status of using biological drugs and some related factors in treating ankylosing spondylitis in Vietnam.</p><p><strong>Methods: </strong>A joint prospective and retrospective cross-sectional descriptive study was conducted on 161 ankylosing spondylitis patients treated with biological drugs at the Centre for Rheumatology between January 2018 and July 2021. Data were collected at the first dose and after 3, 6, 12, 24, and 36 months, including general characteristics, clinical and para-clinical features, drug use status, and related factors.</p><p><strong>Results: </strong>Of the 161 patients, 86.3% were male, with a mean age of 31.1 ± 11.6 years and a mean disease duration of 7.6 ± 6.6 years. Most patients were started on biologics at stage II (46.6%) or III (28.6%). Moreover, 68.9% had active disease based on the Bath Ankylosing Spondylitis Disease Activity Index. The most commonly prescribed first-line therapy was anti-tumor necrosis factor (69.6%), with infliximab the most frequently prescribed drug (44.7%). The rate of biological drug treatment decreased gradually from 100% at the start to 77% after one year and 39.1% after three years. Moreover, 74% of patients changed drugs due to non-response, and 50% discontinued treatment for economic reasons. Age was associated with treatment adherence, and drug change rates were higher in female patients and patients with active disease. Age was significantly associated with drug discontinuation (p < 0.05).</p><p><strong>Conclusion: </strong>Infliximab was the most commonly prescribed first-line drug. The rate of biological therapy gradually decreased after three years. Most patients changed drugs due to non-response, and many discontinued the drugs for economic reasons. Among the individual and clinical factors, age was associated with treatment adherence.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"222-227"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/5c/MSM-35-222.PMC10545927.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41127081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Private Healthcare Sector in Riyadh Region: Size, Services, and Alignment with the Saudi Ministry of Health Priorities.","authors":"Hassan Alshahrani,&nbsp;Naif Al-Matrafi,&nbsp;Nujud Al-Qahtani,&nbsp;Rajaa Taliby,&nbsp;Muna Hassanein,&nbsp;Ibtehaj Al-Rowilly","doi":"10.5455/msm.2023.35.172-177","DOIUrl":"10.5455/msm.2023.35.172-177","url":null,"abstract":"<p><strong>Background: </strong>Mapping exercises are important to inform development of interventions aiming to enhance private sector's contribution towards achieving health systems objectives.</p><p><strong>Objective: </strong>To map size, types, and distribution of private health institutions, and to identify the services they offer, and their alignment with Ministry of Health priorities.</p><p><strong>Methods: </strong>A cross-sectional study targeted licensed, for-profit private health institutions in Riyadh Region, Saudi Arabia. Secondary data were collected from Department of Private Health Institutions in Riyadh and the Ministry of Health Year Statistical Book. Descriptive statistics were employed to analyze the collected data.</p><p><strong>Results: </strong>Private hospitals increased from 40 (2017) to 46 (2021), with private sector hospital beds rising from 5,426 (2017) to 6,339 (2021). Pharmaceutical institutions comprised 55.4% of private health institutions, followed by polyclinics (23%) and supportive health services centers (17.1%). Laboratories, hospitals, and clinics represented 2%, 1%, and 0.5% of private health institutions respectively. Ambulance and radiology service centers were least available private health institutions at 0.1%. Home healthcare, remote care, telemedicine, family medicine, and long-term care were offered by 1.3%, 0.5%, 0.4%, and 0.1% of private health institutions respectively. Private hospitals accounted for 41.4% of total hospitals and private hospitals beds constituted 30.9% of Riyadh's total, with an average of 137.8 beds per hospital. Around 82% of private health institutions were in Riyadh city, with around 18% in peripheral provinces.</p><p><strong>Conclusion: </strong>Private healthcare sector has witnessed substantial growth, primarily influenced by supply rather than demand dynamics. Incentives are essential to promote investment in Ministry of Health priorities.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"172-177"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c5/5c/MSM-35-172.PMC10545926.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Medication Use Among Adolescents in Sarajevo Canton.","authors":"Vanja Piljak,&nbsp;Selma Skrbo,&nbsp;Naida Omerovic,&nbsp;Anela Hadzifejzovic Trnka,&nbsp;Dina Lagumdzija,&nbsp;Nermina Ziga Smajic","doi":"10.5455/msm.2023.35.178-183","DOIUrl":"https://doi.org/10.5455/msm.2023.35.178-183","url":null,"abstract":"<p><strong>Background: </strong>Adolescents are a susceptible population in terms of medication use. They are not only inclined to abuse illegal substances but are also prone to nonmedical medication use, which exposes them to a significant risk of various adverse drug reactions (ADR).</p><p><strong>Objective: </strong>This research aims to assess medication use among adolescents in Sarajevo Canton.</p><p><strong>Methods: </strong>This paper features information about the most frequently used medications, reasons for their use, sources of their procurement, ADR and concurrent use with other medications and/or alcohol. To obtain this data, a questionnaire with open- and close-ended questions was created. The survey was conducted online and 444 participants were included.</p><p><strong>Results: </strong>Medications were used by 90.1% of adolescents. The most commonly used medications were non-opioid analgesics, antibiotics, dietary supplements, antihistamines and benzodiazepines. Mild to moderate pain was the most frequent reason for medication use. Participants were at risk of ADR, drug-drug interactions (DDI), and drug-alcohol interactions.</p><p><strong>Conclusion: </strong>It is up to healthcare workers, especially pharmacists, to educate and guide adolescent patients on rational medication use and inform them about potential dangers following the use of these medications.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"178-183"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/72/MSM-35-178.PMC10545922.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41175091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presence of Type 1 Diabetes-Related Autoantibodies in Pediatric Population in Bosnia and Herzegovina.","authors":"Lamija Zecevic-Pasic,&nbsp;Suzana Tihic-Kapidzic,&nbsp;Snijezana Hasanbegovic,&nbsp;Ermin Begovic,&nbsp;Refet Gojak,&nbsp;Nejra Dzananovic","doi":"10.5455/msm.2023.35.190-195","DOIUrl":"10.5455/msm.2023.35.190-195","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus type 1 (T1D) is an autoimmune organ-specific disease with a wide range of clinical manifestations, in which the β cells of the pancreatic islets of Langerhans are destroyed by the action of autoreactive T lymphocytes and the formation of autoantibodies against β cell components. Among used serological markers of T1D, anti-glutamic acid decarboxylase antibodies (GAD65), anti-tyrosine phosphatase antibodies (IA2), islet cell antibodies (ICA), insulin autoantibodies (IAA) and anti-zinc transporter antibodies (Zn-T8) are of great significance.</p><p><strong>Objective: </strong>This study aimed to analyze presence of type 1 diabetes-related autoantibodies (GAD65, IA2, ICA, IAA and Zn-T8 and effects of age and gender on their occurrence in pediatric population.</p><p><strong>Methods: </strong>Sixty seven (N=67) T1D pediatric patients were included in the study. The levels of immunological parameters such as anti-glutamic acid decarboxylase antibodies (GAD-Ab), anti-tyrosine phosphatase antibodies (IA2-Ab), islet cell antibodies (ICA) and insulin autoantibodies (IAA) were determined by chemiluminescence immunoassay (CLIA) and anti-zinc transporter antibodies (Zn-T8-Ab) were determined by enzyme-linked immunosorbent assay (ELISA). For statistical analysis, we used SPSS statistical program.</p><p><strong>Results: </strong>Our study revealed that among 67 patients with T1D (40 male and 27 female), with an average age of 12,1±3,9 years. The average age of diabetes diagnosis was 6,15±3,29 years. 24 (35,8%) cases were positive for GAD65, 15 (22,4%) for ICA, 34 (50,7%) for IAA, 16 (23,9%) for IA2 and 36 (53,7%) for Zn-T8. The largest number of patients had single positive antibody, the most dominated among them was IAA dominated (40,9%), then Zn-T8 (31,8%). According to Spearman correlation test Zn-transporter shows a significant positive correlation with age of the participants (p=0.027) and disease duration (p=0.006). Anti IA2 shows significant negative correlation with HbA1c (p=0.043). Zn-transporter is associated with patients age and duration of T1D.</p><p><strong>Conclusion: </strong>In most cases, patients with T1D are positive for at least one of the specific autoantibodies. Zn-T8 is the most frequently detected and is an important serological marker of type 1 diabetes mellitus. Gender effects on autoantibodies seems to be insignificant, while age alongside disease duration shows important effects.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"190-195"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/54/MSM-35-190.PMC10545919.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41176076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Satisfaction of Patients with HIV/AIDS Infection from the Care Provided in the Special Infection Unit of University General Hospital of Alexandroupoli.","authors":"Petros Ouzounakis,&nbsp;Lambrini Kourkouta,&nbsp;Aikaterini Frantzana,&nbsp;Christos Iliadis,&nbsp;Areti Tsaloglidou,&nbsp;Konstantinos Koukourikos,&nbsp;Christos Sialakis,&nbsp;Evaggelos Alexopoulos","doi":"10.5455/msm.2023.35.184-189","DOIUrl":"https://doi.org/10.5455/msm.2023.35.184-189","url":null,"abstract":"<p><strong>Background: </strong>C HIV/AIDS infection is characterized by a very low number of T lymphocytes (CD4), which makes sufferers vulnerable to various infections, and so they seek continuous care in Special Infections Units.</p><p><strong>Objective: </strong>The purpose of the survey is to investigate the factors that contribute to the satisfaction derived from the health services provided to people living with the human immunodeficiency virus; and they are monitored at the Special Infections Unit of the University General Hospital of Alexandroupoli.</p><p><strong>Methods: </strong>All patients who came to the Special Infections Unit of the University General Hospital of Alexandroupoli during the period June - July 2021 were asked to complete an anonymous questionnaire on satisfaction derived from the health services provided (E - PQ - SPCSS) and satisfaction derived from their work and quality of life (Occupational Stress Questionnaire, JCQ). The statistical package SPSS 19.0 was used for the statistical analysis of the data. With the help of the ANOVA statistical test, the differences between the variables were checked. P-Value in all audits was set at 0.05. Values showing equal to or less than 0.05 were considered statistically significant.</p><p><strong>Results: </strong>They were 85 patients who participated. Amongst them, they were mainly men (75.3%), the mean age was 35-50 years (50.6%), residents of Thrace (62.3%). 37.7% of the participants said they had some difficulty accessing SIU. Quality of life was positively correlated with education (p<0.001) where the higher reported level of education was, the higher satisfaction rates were. A positive correlation (p<0.001) was also observed amongst income rates where the higher incomes reported, the higher the satisfaction rates were. Lower incomes were significantly associated (p = 0.029) with mental disorders (anxiety, depression). Quality of life was positively associated with both satisfaction with medical as well as nursing care (p <0.008). The adequacy and clarity of the information the patients receive from SIU physicians during their visit shows a significant positive correlation (p<0.001). In addition, there is a significant correlation regarding the problems patients may have experienced in the last 6 months in terms of access to treatment (p<0.021).</p><p><strong>Conclusion: </strong>Participants showed high satisfaction rates from the medical and nursing care provided at the SIU of the PGNA. The opportunity of expression given to users - patients through satisfaction studies promotes and creates a climate of trust between them and the decision-making teams of health units.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/00/MSM-35-184.PMC10545923.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41173518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery.","authors":"Xanthi Anthoulaki,&nbsp;Efthimios Oikonomou,&nbsp;Anastasia Bothou,&nbsp;Stavroula Papanikolopoulou,&nbsp;Konstantinos Nikolettos,&nbsp;Christos Damaskos,&nbsp;Nikolaos Garbis,&nbsp;Dimitrios Kyriakou,&nbsp;Theopi Nalbanti,&nbsp;Georgios Iatrakis,&nbsp;Nikolaos Nikolettos,&nbsp;Panagiotis Tsikouras","doi":"10.5455/msm.2023.35.234-243","DOIUrl":"10.5455/msm.2023.35.234-243","url":null,"abstract":"<p><strong>Background: </strong>Pregnancy is an admirable biological process, resulting in significant changes in many of the body's normal systems so that they can support the development of the fetus. These changes involve hormonal changes, weight gain, immune system regulation, and others that need to be synchronized to maintain both maternal and fetal health.</p><p><strong>Objective: </strong>The purpose of this study was to compare gut microbiome in neonates born by caesarean section and vaginal seeding with gut microbiomes of neonates born by caesarean section without vaginal seeding and neonates born by vaginal delivery.</p><p><strong>Methods: </strong>In Democritus University of Thrace, from 2019 to 2022, gut microbiomes were compared for three groups of neonates. Group A included 110 neonates born by CS who underwent vaginal seeding, group B included 85 neonates born by CS without vaginal seeding and group C included 95 neonates born by vaginal delivery.</p><p><strong>Results: </strong>Vaginal seeding in neonates born with CS resulted in gut microbiome which was similar to the gut microbiome of neonates born by vaginal delivery (including lactobacillus species and bacteroides). On the contrary, gut microbiome of neonates born by CS without vaginal seeding was \"limited\".</p><p><strong>Conclusion: </strong>According to our findings, vaginal seeding alters the gut microbiome of the neonates born with CS. However, there is a need for further investigation to prove its efficacy and its safety for the neonate.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"35 3","pages":"234-243"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fd/90/MSM-35-234.PMC10545928.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}