Olivier Gheysens, Matthieu Pelletier-Galarneau, Giorgio Treglia, Ora Israel, Francois Jamar, Gad Abikhzer
{"title":"Summary: EANM/SNMMI Release Joint Guideline/Procedure Standard for [<sup>18</sup>F]FDG Hybrid PET Use in Infection and Inflammation in Adults, Version 2.0.","authors":"Olivier Gheysens, Matthieu Pelletier-Galarneau, Giorgio Treglia, Ora Israel, Francois Jamar, Gad Abikhzer","doi":"10.2967/jnumed.125.269538","DOIUrl":"10.2967/jnumed.125.269538","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"480-481"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Brief Report on the Results of the 2024 National Survey of Nuclear Medicine Conducted by the Chinese Society of Nuclear Medicine.","authors":"Jing Wang, Xiaoli Lan, Hongcheng Shi, Sijin Li","doi":"10.2967/jnumed.124.269044","DOIUrl":"https://doi.org/10.2967/jnumed.124.269044","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nick D van Rijsewijk, Philipp Lanz, Marjan Wouthuyzen-Bakker, Andor W J M Glaudemans, Frank F A IJpma
{"title":"Evaluating Bone Healing with [<sup>18</sup>F]NaF PET/CT During Bone Segment Transport in Femoral Fracture Treatment.","authors":"Nick D van Rijsewijk, Philipp Lanz, Marjan Wouthuyzen-Bakker, Andor W J M Glaudemans, Frank F A IJpma","doi":"10.2967/jnumed.124.268913","DOIUrl":"https://doi.org/10.2967/jnumed.124.268913","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Radiopharmaceuticals: A Sustainable Path to the Improvement of Patient Care.","authors":"Andrei Gafita, Andrew R Menard, Lilja B Solnes","doi":"10.2967/jnumed.124.268608","DOIUrl":"10.2967/jnumed.124.268608","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"186"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Mosconi, Matilde Nerattini, Valentina Berti, Dawn C Matthews, Caroline Andy, Schantel Williams, Matthew Fink, Alberto Pupi, Roberta Diaz Brinton
{"title":"Maintaining the Evidence for In Vivo Brain Estrogen Receptor Density by Neuroendocrine Aging and Relationships with Cognition and Symptomatology.","authors":"Lisa Mosconi, Matilde Nerattini, Valentina Berti, Dawn C Matthews, Caroline Andy, Schantel Williams, Matthew Fink, Alberto Pupi, Roberta Diaz Brinton","doi":"10.2967/jnumed.124.269268","DOIUrl":"10.2967/jnumed.124.269268","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"331-332"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastrin-Releasing Peptide Receptor Imaging and Therapy in the Era of Personalized Medicine.","authors":"Clément Morgat, Andrei Iagaru, Elif Hindié","doi":"10.2967/jnumed.124.268861","DOIUrl":"10.2967/jnumed.124.268861","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"207-208"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Gergely Kovacs, Claes Nøhr Ladefoged, Jacob Bak Rosenkjær, Fatima Mawassi, Line Akiti Hingelberg, Anna Olga Aaskilde Laursen, Barbara Malene Fischer, Flemming Littrup Andersen
{"title":"Is the Clinical Implementation of In-House Artificial Intelligence-Developed Algorithms Happening?","authors":"David Gergely Kovacs, Claes Nøhr Ladefoged, Jacob Bak Rosenkjær, Fatima Mawassi, Line Akiti Hingelberg, Anna Olga Aaskilde Laursen, Barbara Malene Fischer, Flemming Littrup Andersen","doi":"10.2967/jnumed.124.268156","DOIUrl":"10.2967/jnumed.124.268156","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"183-185"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Floriane Barbry, Benjamin Chevalier, Amandine Beron, Georges Lion, Samuel Boury, Camille Marciniak, Clio Baillet, Christine Do Cao, Arnaud Jannin
{"title":"Redifferentiation of a RET-Fusion, Radioiodine-Refractory, Differentiated Thyroid Cancer with Selpercatinib: Flip-Flop Between [<sup>18</sup>F]FDG PET/CT and <sup>131</sup>I Posttreatment Scanning.","authors":"Floriane Barbry, Benjamin Chevalier, Amandine Beron, Georges Lion, Samuel Boury, Camille Marciniak, Clio Baillet, Christine Do Cao, Arnaud Jannin","doi":"10.2967/jnumed.124.268539","DOIUrl":"10.2967/jnumed.124.268539","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"330"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Scientist to Analyst to Strategist: Aharon (Ronny) Gal Talks with Ken Herrmann and Johannes Czernin About Leadership in Multinational Pharma.","authors":"Aharon Ronny Gal, Ken Herrmann, Johannes Czernin","doi":"10.2967/jnumed.124.269177","DOIUrl":"10.2967/jnumed.124.269177","url":null,"abstract":"","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"163-165"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Aliaga, Joseph Therriault, Kely Monica Quispialaya, Arturo Aliaga, Robert Hopewell, Nesrine Rahmouni, Arthur C Macedo, Peter Kunach, Jean-Paul Soucy, Gassan Massarweh, Aida Abreu Diaz, Tharick A Pascoal, Andreia Rocha, Marie-Christine Guiot, Luiza S Machado, Marco Antônio De Bastiani, Débora Guerini de Souza, Diogo O Souza, Serge Gauthier, Eduardo R Zimmer, Pedro Rosa-Neto
{"title":"Comparison Between Brain and Cerebellar Autoradiography Using [<sup>18</sup>F]Flortaucipir, [<sup>18</sup>F]MK6240, and [<sup>18</sup>F]PI2620 in Postmortem Human Brain Tissue.","authors":"Antonio Aliaga, Joseph Therriault, Kely Monica Quispialaya, Arturo Aliaga, Robert Hopewell, Nesrine Rahmouni, Arthur C Macedo, Peter Kunach, Jean-Paul Soucy, Gassan Massarweh, Aida Abreu Diaz, Tharick A Pascoal, Andreia Rocha, Marie-Christine Guiot, Luiza S Machado, Marco Antônio De Bastiani, Débora Guerini de Souza, Diogo O Souza, Serge Gauthier, Eduardo R Zimmer, Pedro Rosa-Neto","doi":"10.2967/jnumed.124.267539","DOIUrl":"10.2967/jnumed.124.267539","url":null,"abstract":"<p><p>Our objective was to evaluate the in vitro binding properties of [<sup>18</sup>F]flortaucipir, 6-(fluoro-<sup>18</sup>F)-3-(1<i>H</i>-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([<sup>18</sup>F]MK6240), and 2-(2-([<sup>18</sup>F]fluoro)pyridin-4-yl)-9<i>H</i>-pyrrolo[2,3-b:4,5c']dipyridine ([<sup>18</sup>F]PI2620) head-to-head in postmortem human brain tissue. <b>Methods:</b> Autoradiography was used to assess uptake of [<sup>18</sup>F]flortaucipir, [<sup>18</sup>F]MK6240, and [<sup>18</sup>F]PI2620 in control and Alzheimer disease (AD) autopsy-confirmed brain tissues. The study focused on the analysis of the prefrontal cortex, hippocampus, and cerebellum sections in 12 controls and 12 AD cases, as well as whole-brain hemisphere in 1 control and 1 AD sample, for each radiotracer. The binding values of [<sup>18</sup>F]flortaucipir, [<sup>18</sup>F]MK6240, and [<sup>18</sup>F]PI2620 were calculated from regions of interest manually drawn in the prefrontal, hippocampal, and cerebellar cortices. <b>Results:</b> For all 3 radioligands investigated, we observed significant tracer binding differences between control and AD tissues in the whole-brain hemisphere, prefrontal cortex, and hippocampus but not in the cerebellar cortex. [<sup>18</sup>F]MK6240 and [<sup>18</sup>F]PI2620 had higher effect sizes to differentiate control and AD cases than did [<sup>18</sup>F]flortaucipir. Bland-Altman analyses revealed strong correlations between [<sup>18</sup>F]MK6240, [<sup>18</sup>F]PI2620, and [<sup>18</sup>F]flortaucipir, with the highest agreement found for [<sup>18</sup>F]MK6240 versus [<sup>18</sup>F]PI2620. <b>Conclusion:</b> The 3 radioligands showed comparable diagnostic properties to assess tau aggregates in vitro. Binding to AD brain tissues was higher for [<sup>18</sup>F]MK6240 and [<sup>18</sup>F]PI2620 than for [<sup>18</sup>F]flortaucipir. Additionally, [<sup>18</sup>F]MK6240 and [<sup>18</sup>F]PI2620 had greater selectivity, displaying decreased uptake in control brain tissue compared with [<sup>18</sup>F]flortaucipir. These results might provide insights on ongoing initiatives to create a universal scale for tau imaging studies.</p>","PeriodicalId":94099,"journal":{"name":"Journal of nuclear medicine : official publication, Society of Nuclear Medicine","volume":" ","pages":"123-129"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}