J Duvernay, B Garreau, P-A Dubreuil, M Bondaz, C Majoufre, M Schlund
{"title":"Lymph node metastasis in level IIb neck dissection for clinically node-negative oral squamous cell carcinoma patients: an 11-year retrospective study.","authors":"J Duvernay, B Garreau, P-A Dubreuil, M Bondaz, C Majoufre, M Schlund","doi":"10.1016/j.ijom.2024.12.004","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.12.004","url":null,"abstract":"<p><p>The most common complication associated with selective neck dissection is spinal accessory nerve dysfunction and shoulder disability, which result from level IIb dissection. The main objective of this study was to evaluate the incidence of level IIb lymph node metastasis in clinically node-negative (cN0) oral squamous cell carcinoma (OSCC) patients. Patients presenting with cN0 OSCC between November 2012 and November 2023 were included retrospectively. The primary endpoint was the incidence of level IIb lymph node metastasis in these patients. A total of 389 patients (527 supraomohyoid neck dissections) who presented during the 11-year period were included in this study . The incidence of occult cervical lymph node metastasis was 25.2%. The median number of level IIb lymph nodes removed was 5.5. No metastatic lymph node was found at level IIb. The absence of metastatic involvement at level IIb and high prevalence of shoulder dysfunction caused by injury to the spinal accessory nerve during level IIb neck dissection challenges the necessity of level IIb neck dissection in cN0 OSCC.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E A Prostakishina, E A Sidenko, E S Kolegova, M R Patysheva, G A Kononova, E L Choinzonov
{"title":"Premalignant lesions of the oral cavity: a narrative review of factors and mechanisms of transformation into cancer.","authors":"E A Prostakishina, E A Sidenko, E S Kolegova, M R Patysheva, G A Kononova, E L Choinzonov","doi":"10.1016/j.ijom.2024.12.006","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.12.006","url":null,"abstract":"<p><p>Oral squamous cell carcinoma (OSCC) is the most common type of head and neck cancer. The development and progression of OSCC are closely linked to various aetiological factors. Early signs of OSCC may manifest as oral lesions, genetic abnormalities, and chronic inflammation. Lesions with dysplastic features have a high risk of malignant transformation into OSCC. Moreover, dysplastic lesions are characteristic of many oral potentially malignant disorders (OPMDs). Currently, there is no unified standard of treatment for OPMD patients, due to the variability in risk factors and mechanisms of transformation. Therefore, it is essential to detect and manage OPMDs at an early stage in order to prevent their malignant transformation into OSCC. This necessitates analysing OPMD mechanisms to identify objective markers for predicting the risk of malignant transformation. The aim of this review was to describe the process of OPMD transformation into OSCC under the influence of environmental, immune, microbiome, and molecular factors.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T W Nielsen, M B Holte, G Berg-Beckhoff, J J Thorn, J Ingerslev, E M Pinholt
{"title":"Three-dimensional assessment of temporomandibular joint changes following maxillomandibular advancement surgery: a five-year follow-up study.","authors":"T W Nielsen, M B Holte, G Berg-Beckhoff, J J Thorn, J Ingerslev, E M Pinholt","doi":"10.1016/j.ijom.2024.12.002","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.12.002","url":null,"abstract":"<p><p>This study aimed to evaluate changes of the temporomandibular joint (TMJ) following maxillomandibular advancement surgery (MMA), long-term postoperative skeletal relapse, and progressive condylar resorption (PCR) development. Preoperative and postoperative cone beam computed tomography(2 weeks, 5 years) of 50 patients (33 female, 17 male; mean age 25.6 years) were assessed three-dimensionally. Compared to the preoperative state, the largest long-term changes of the TMJ were observed in the condyles: mean volume decrease of 9.94% for the right condyle and 8.35% for the left. Condylar volume changes contributed most to the changes in condylar height (effect size right/left, η<sup>2</sup> = 0.71/0.72) and horizontal postoperative skeletal relapse (η<sup>2</sup> = 0.22/0.20). In contrast, glenoid fossa and joint space changes were modest and unassociated with skeletal relapse. Five female patients (10%) showed signs of PCR, with a mean reduction in condylar volume of 32%, a significant loss of condylar height and skeletal relapse. In conclusion, at 5 years following MMA, mainly condylar volume changes were observed, which had the largest effect on long-term postoperative skeletal relapse when compared to glenoid fossa and joint space changes. PCR occurred in 10% of the patients and was related to a significant loss of condylar height and skeletal relapse.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Composite graft for the prevention and correction of a deep labiomental fold after advancement genioplasty.","authors":"F Carlino","doi":"10.1016/j.ijom.2024.11.006","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.11.006","url":null,"abstract":"<p><p>When an advancement genioplasty exceeds 3-4 mm an unpleasant fold may arise between lower lip and chin, especially in patients with thin skin. To flatten the labiomental fold, a solid graft can be inserted into the concavity between alveolar process and chin prominence. An original technique is proposed that uses a composite graft made of a bone block fixed directly to the mandibular basal bone and covered with a layer of cartilage, to overcome the flaws associated with previously described techniques. This technique was used over a 7-year period to treat 38 patients, either to prevent or to correct an excessively deep labiomental fold after advancement genioplasty, or simply to fill an existing deep fold even though a genioplasty was not performed. Only two cases of failure occurred: one due to suture dehiscence, the other due to infection of the graft. The graft also provides support to the lower lip and corrects the sagittal discrepancy between the basal bone (i.e. chin) and alveolar bone (i.e. teeth and lower lip) that often coexists in these patients. The procedure takes only a few minutes and presents a minimal risk of complications; therefore, it can be considered a simple and effective technique.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Morikawa, M Shingyouchi, T Ariizumi, A Watanabe, T Shibahara, A Katakura
{"title":"Performance of image processing analysis and a deep convolutional neural network for the classification of oral cancer in fluorescence visualization.","authors":"T Morikawa, M Shingyouchi, T Ariizumi, A Watanabe, T Shibahara, A Katakura","doi":"10.1016/j.ijom.2024.11.010","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.11.010","url":null,"abstract":"<p><p>The aim of this prospective study was to determine the effectiveness of screening using image processing analysis and a deep convolutional neural network (DCNN) to classify oral cancers using non-invasive fluorescence visualization. The study included 1076 patients with diseases of the oral mucosa (oral cancer, oral potentially malignant disorders (OPMDs), benign disease) or normal mucosa. For oral cancer, the rate of fluorescence visualization loss (FVL) was 96.9%. Regarding image processing, multivariate analysis identified FVL, the coefficient of variation of the G value (CV), and the G value ratio (VRatio) as factors significantly associated with oral cancer detection. The sensitivity and specificity for detecting oral cancer were 96.9% and 77.3% for FVL, 80.8% and 86.4% for CV, and 84.9% and 87.8% for VRatio, respectively. Regarding the performance of the DCNN for image classification, recall was 0.980 for oral cancer, 0.760 for OPMDs, 0.960 for benign disease, and 0.739 for normal mucosa. Precision was 0.803, 0.821, 0.842, and 0.941, respectively. The F-score was 0.883, 0.789, 0.897, and 0.828, respectively. Sensitivity and specificity for detecting oral cancer were 98.0% and 92.7%, respectively. The accuracy for all lesions was 0.851, average recall was 0.860, average precision was 0.852, and average F-score was 0.849.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V L van Roey, A B Mink van der Molen, I M J Mathijssen, I Akota, C de Blacam, C C Breugem, E M Craveiro Matos, K Dávidovics, C Dissaux, K Dowgierd, A Eberlinc, M Hakelius, A Heliövaara, G Z Hens, R H Khonsari, M Krimmel, S Lux, H Mark, F Mazzoleni, M C Meazzini, M Munill Ferrer, M E Nienhuijs, P Peterson, K Piacentile, J Rubio Palau, H C Sylvester-Jensen, V Zafra Vallejo, S L Versnel
{"title":"Between unity and disparity: current treatment protocols for common orofacial clefts in European expert centres.","authors":"V L van Roey, A B Mink van der Molen, I M J Mathijssen, I Akota, C de Blacam, C C Breugem, E M Craveiro Matos, K Dávidovics, C Dissaux, K Dowgierd, A Eberlinc, M Hakelius, A Heliövaara, G Z Hens, R H Khonsari, M Krimmel, S Lux, H Mark, F Mazzoleni, M C Meazzini, M Munill Ferrer, M E Nienhuijs, P Peterson, K Piacentile, J Rubio Palau, H C Sylvester-Jensen, V Zafra Vallejo, S L Versnel","doi":"10.1016/j.ijom.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.12.001","url":null,"abstract":"<p><p>There is considerable variability in the management of common orofacial clefts across Europe, reflecting differing opinions on optimal treatments. An updated overview of treatment protocols for orofacial clefts across 26 expert centres in the European Reference Network CRANIO is presented here. A structured questionnaire was distributed to map the surgical protocol and additional standard procedures for cleft palate (CP), unilateral cleft lip and palate (UCLP), and bilateral cleft lip and palate (BCLP). A surgical protocol was defined as the unique combination of a sequence of standard surgeries, their timing, and the surgical techniques employed. Overall, 33 unique surgical protocols for CP, 54 for UCLP, and 51 for BCLP were identified. Notable findings included the trend towards early hard palate closure, uniform timing of lip closure, and the popularity of primary cleft rhinoplasty. Nevertheless, practice variations were most pronounced in the timing of alveolar closure, the number of standard surgeries, and the application of additional standard procedures. This study highlights the diversity of treatment protocols across Europe, despite considerable convergence of treatment practices over time. To allow for further convergence, establishing objective criteria for protocol selection, adequate documentation of customizations, and consensus on the terminology of surgical techniques, are necessary.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Salinas Fredricson, C Krüger Weiner, M Ulmner, A Naimi-Akbar
{"title":"Craniomaxillofacial trauma increases the risk of temporomandibular joint disorders and days of work disability-a SWEREG-TMD registry-based study.","authors":"A Salinas Fredricson, C Krüger Weiner, M Ulmner, A Naimi-Akbar","doi":"10.1016/j.ijom.2024.11.011","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.11.011","url":null,"abstract":"<p><p>Although craniomaxillofacial (CMF) trauma is a factor recognized as contributing to the development of temporomandibular joint disorders (TMJD), large population-based research on CMF trauma and subsequent TMJD is lacking. Additionally, it is unknown how previous CMF trauma affects work disability reimbursements for patients with TMJD (pwTMJD). This Swedish registry-based study included 33,315 pwTMJD matched to 333,122 individuals from the general population. Both a case-control design and a cohort design were used in this study to evaluate the association between CMF trauma and TMJD, and to investigate how CMF trauma impacts the number of days on work disability among pwTMJD. The main study finding was that many types of previous CMF trauma were strongly associated with TMJD, with mandibular fractures having the strongest association (adjusted odds ratio 11.4). Furthermore, the strongest association for an increased number of annual days on work disability was found for pwTMJD with a history of CMF trauma. These results suggest that CMF trauma influences the developmental path of TMJD, even in a population-based sample.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Sharba, A Buch, D-M Beek, S E Nørholt, T Xi, K Stokbro
{"title":"Safety of vertical osteotomies in segmental Le Fort I procedures: a one-year radiological follow-up study.","authors":"N Sharba, A Buch, D-M Beek, S E Nørholt, T Xi, K Stokbro","doi":"10.1016/j.ijom.2024.10.013","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.10.013","url":null,"abstract":"<p><p>The aim of this study was to evaluate dental and periodontal injuries and radiological bone healing at vertical osteotomies in patients treated with segmental Le Fort I (LFI) osteotomy, using cone beam computed tomography (CBCT) scans. This retrospective study analyzed 105 patients who underwent segmental LFI osteotomy. Vertical osteotomies were performed between the lateral incisor and canine using a bur and osteotome. CBCT scans were taken preoperatively and at 1-week and 1-year follow-ups. Measurements at 1-week included interdental distances, root injuries, and periodontal detachment, while 1-year follow-up assessed endodontic treatment and osteotomy healing. Results showed no damage to the 420 roots at risk, though 38 roots had osteotomy extensions into the periodontal ligament. The mean preoperative minimum distance between roots was significantly different between sites with intact and detached periodontal ligaments (P < 0.001). One tooth required endodontic treatment at 1-year follow-up. Incomplete healing of vertical osteotomies was more frequent in female patients (P = 0.012). The findings suggest that segmental LFI osteotomy is safe when performed with a bur and osteotome, provided a minimum distance of 2.5 mm between roots is maintained.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in mandibular angle and intergonial width after bilateral sagittal split ramus osteotomy or bimaxillary surgery with/without counterclockwise rotation.","authors":"D Bi, H Gao, M Q H Al-Watary, X Sun, Q Zhao, J Li","doi":"10.1016/j.ijom.2024.09.014","DOIUrl":"https://doi.org/10.1016/j.ijom.2024.09.014","url":null,"abstract":"<p><p>The aim of this retrospective study was to evaluate the morphological changes in the mandibular angle area after orthognathic surgery with or without mandibular counterclockwise rotation in Class II deformity patients, and to investigate the associated factors. Computed tomography scans obtained preoperatively (T0), within 1 month postoperatively (T1), and 6 months postoperatively (T2) were collected from 58 patients who underwent either bilateral sagittal split ramus osteotomy (group I), bimaxillary surgery with mandibular counterclockwise rotation (group II), or bimaxillary surgery without mandibular counterclockwise rotation (group III). The intergonial width increased after surgery, by 2.78 ± 2.02 mm in group I, 2.86 ± 2.81 mm in group II, and 2.53 ± 2.42 mm in group III (all P < 0.001). The mandibular angle (MA) increased in group I (ΔMA 4.76 ± 2.79°; P < 0.001) and group III (ΔMA 3.50 ± 2.58°; P < 0.001); however no significant increase was observed in group II. The increase in intergonial width was positively correlated with the lateral displacement of the proximal segment. Counterclockwise rotation of the proximal segment resulted in an increase in MA, while counterclockwise rotation resulted in a reduction in this increasing trend. The results indicate that reducing the displacement and rotation of the proximal segments is key to minimizing changes in the mandibular angle area.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}