International journal of oral and maxillofacial surgery最新文献

Does previous neck dissection or irradiation mitigate the response to immunotherapy in advanced/metastatic head and neck squamous cell carcinoma? 既往颈部清扫或放疗是否会减轻晚期/转移性头颈部鳞状细胞癌患者对免疫治疗的反应？

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-08 DOI: 10.1016/j.ijom.2026.04.018

L Kampel, Y Oestreicher-Kedem, G Horowitz, O Gutfeld, I Finkel, N Muhanna, A Warshavsky

{"title":"Does previous neck dissection or irradiation mitigate the response to immunotherapy in advanced/metastatic head and neck squamous cell carcinoma?","authors":"L Kampel, Y Oestreicher-Kedem, G Horowitz, O Gutfeld, I Finkel, N Muhanna, A Warshavsky","doi":"10.1016/j.ijom.2026.04.018","DOIUrl":"https://doi.org/10.1016/j.ijom.2026.04.018","url":null,"abstract":"Immunotherapy has brought new hope to patients with locally advanced, recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). This study aimed to evaluate the outcomes at our institution, focusing on the response to immunotherapy in patients whose draining lymph nodes were previously dissected and/or irradiated. A retrospective study on patients treated with immunotherapy, indicated for unresectable or R/M HNSCC between 2014 and 2024, was conducted. Treatment response and survival outcomes were analysed. Eighty-four patients were identified, including 26 patients (31%) who were treated with immunotherapy without any previous therapy to the draining lymph nodes and 58 patients who had been treated with neck dissection or radiotherapy (ND/RT) before immunotherapy. The latter were significantly younger (63 vs 71 years; P = 0.037) with fewer distant metastases upon initiation of immunotherapy (7% vs 31%; P = 0.007). Combined positive score <1 was the only factor significantly associated with disease progression, adjusted for age, previous ND/RT, and metastatic disease (P = 0.038). When ND/RT preceded immunotherapy, higher rates of disease progression were noted in comparison to naive necks, but the difference did not reach statistical significance (54% vs 33%, respectively; P = 0.134). Overall, previous dissection or radiotherapy to draining lymph nodes did not negatively affect the response to immunotherapy nor the survival outcomes in advanced or R/M HNSCC.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In reply to the comment on "Mixed reality-assisted orthognathic surgery with pre-bent titanium plates". 回复“预弯曲钛板混合现实辅助正颌手术”的评论。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-08 DOI: 10.1016/j.ijom.2026.04.044

L Huang, H Li, V Yau, E Luo

引用次数: 0

Comment on: "Mixed reality-assisted orthognathic surgery with pre-bent titanium plates". 评论：“预弯曲钛板混合现实辅助正颌手术”。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-08 DOI: 10.1016/j.ijom.2026.04.045

R Grillo

引用次数: 0

Optimizing prosthetic outcomes in navigation-assisted zygomatic implant surgery: a novel protocol for real-time screw channel alignment. 优化导航辅助颧骨植入手术的假体效果：一种实时螺钉通道对齐的新方案。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.030

S-H Chen, H-H Ko, T-H Ho

{"title":"Optimizing prosthetic outcomes in navigation-assisted zygomatic implant surgery: a novel protocol for real-time screw channel alignment.","authors":"S-H Chen, H-H Ko, T-H Ho","doi":"10.1016/j.ijom.2026.04.030","DOIUrl":"https://doi.org/10.1016/j.ijom.2026.04.030","url":null,"abstract":"Current dynamic navigation systems often fail to display the real-time rotational phase (timing) of the implant. This limitation is particularly critical for the NobelZygoma 45° implant (Nobel Biocare), where the 45° angle between the prosthetic platform and the implant axis necessitates precise rotational control. Failure to visualize this orientation can lead to significant deviations in the prosthetic screw channel trajectory, complicating immediate provisionalization. This technical note describes a digital workflow integrating DTX Studio Implant planning software (Nobel Biocare) and the X-Guide navigation system (X-Nav Technologies) to address this limitation. By creating a custom 'angle measurement tool' and merging it with the diagnostic wax-up within a unified coordinate system, clinicians can visualize the target screw channel trajectory intraoperatively. This protocol enables the quantification of rotational deviation, ensuring that the screw channel alignment remains within a clinically acceptable range to enhance the accuracy and structural integrity of prefabricated provisional prostheses.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative MRI analysis of the lateral pterygoid muscle in temporomandibular joint disc displacement: attachment type, volume, and signal intensity. 颞下颌关节盘移位中外侧翼状肌的定量MRI分析：附着类型、体积和信号强度。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.015

B Bilgen

{"title":"Quantitative MRI analysis of the lateral pterygoid muscle in temporomandibular joint disc displacement: attachment type, volume, and signal intensity.","authors":"B Bilgen","doi":"10.1016/j.ijom.2026.04.015","DOIUrl":"https://doi.org/10.1016/j.ijom.2026.04.015","url":null,"abstract":"The role of morphological and radiological characteristics of the lateral pterygoid muscle (LPM) in the progression of temporomandibular joint (TMJ) disc displacement remains uncertain. This study was performed to investigate the association between LPM attachment type, volume, and signal intensity ratios (SIRs) and disc displacement with reduction (DDwR) and without reduction (DDwoR). A total of 188 TMJs from 94 patients were categorized into three groups: healthy controls (n = 62), DDwR (n = 62), and DDwoR (n = 64). LPM attachment type, superior and inferior LPM volumes, and SIRs were assessed using MRI. Receiver operating characteristics (ROC) analyses were applied to evaluate the discriminative ability of volumetric and SIR parameters. LPM attachment type did not differ among the groups (P = 0.36). In contrast, SIRs and superior head volume showed significant intergroup differences, reaching their highest values in the DDwoR group (all P < 0.001). ROC analyses demonstrated good discriminative performance for SIRs and superior head volume in identifying disc displacement, with stronger diagnostic accuracy for DDwoR compared with DDwR. Although a causal relationship cannot be established, the progressive increase in SIRs and superior head volume with increasing severity of disc displacement suggests that these changes reflect secondary adaptive or inflammatory responses of the LPM to altered TMJ biomechanics, associated with disc displacement. Evaluating radiological and morphological LPM characteristics alongside disc position may provide insights into the soft tissue pathophysiology accompanying disc displacement progression.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A complex and debilitating case of craniofacial fibrous dysplasia: challenging resection, reconstruction and prosthetic rehabilitation. 一个复杂和衰弱的颅面纤维发育不良病例：具有挑战性的切除，重建和假肢康复。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.028

S W Guthua, M N Mwasha, M Kamau, K Sarna, K Gathukia, H Koops, M Y Mommaerts

引用次数: 0

Response to the comment on "Free forearm flaps for head and neck reconstruction: fewer revisions and flap failures with two venous anastomoses-a 25-year prospective study". 对“前臂游离皮瓣用于头颈部重建：两静脉吻合术较少的修复和皮瓣失败-一项25年的前瞻性研究”评论的回应。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.023

C J Kuijpers, E M Van Cann, F J Dieleman, J E Bergsma, R J J van Es, A J W P Rosenberg

引用次数: 0

Piano technique for frontal sinus setback: a technical note. 额窦后退的钢琴技巧：技术说明。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.036

M Etemadi Sh, G Tajmiri, T Fattahi

引用次数: 0

Versatility of local flaps in restoring anterior tongue defects. 局部皮瓣在舌前缺损修复中的多功能性。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-07 DOI: 10.1016/j.ijom.2026.04.016

N Mannapperuma, T Ganesarajah, V Ilankovan

引用次数: 0

A clinicopathological study on the associations between ranulas and autoimmune diseases. 牛痘与自身免疫性疾病相关性的临床病理研究。

IF 2.7

International journal of oral and maxillofacial surgery Pub Date : 2026-05-06 DOI: 10.1016/j.ijom.2026.03.029

X Hong, G-M Zhou, J Li, X Ye, Y-T Lin, Y-L Chen, Y-L Deng, F Wang, G-Y Yu, H-Y Yang

{"title":"A clinicopathological study on the associations between ranulas and autoimmune diseases.","authors":"X Hong, G-M Zhou, J Li, X Ye, Y-T Lin, Y-L Chen, Y-L Deng, F Wang, G-Y Yu, H-Y Yang","doi":"10.1016/j.ijom.2026.03.029","DOIUrl":"https://doi.org/10.1016/j.ijom.2026.03.029","url":null,"abstract":"The study aimed to investigate autoimmune disease (AD) prevalence in ranula patients, analyse their clinicopathological features, and explore the associations between ADs and ranulas. This cross-sectional study enrolled surgically treated ranula patients between 2021 and 2023. AD diagnosis was established. Clinical, serological, and histopathological features were compared. Among the 102 patients, 36.3% had confirmed ADs (predominantly primary Sjögren syndrome and undifferentiated connective tissue disease), 42.2% had no ADs, and 21.6% were suspected of ADs. In the confirmed AD group, 83.8% developed ranulas before AD diagnosis, and exhibited higher female proportion, older age, reduced salivary function, and positive autoantibodies versus the non-AD group. Sublingual gland pathology revealed multifocal lymphocytic infiltration, fatty replacement, ductal epithelial destruction, and periductal collagen proliferation in confirmed and suspected AD groups, rarely in the non-AD group. Focus score was significantly higher in the confirmed AD group, correlating with mucus extravasation foci (r = 0.718, P < 0.01). Grade 3/4 lesions (Chisholm-Mason system) and lymphoepithelial lesions were significantly associated with ADs (P < 0.001, P = 0.033, respectively). In conclusion, a significant proportion of ranulas are associated with ADs, with distinct clinicopathological features. Characteristic histopathological changes in the sublingual gland may indicate ADs, which could potentially contribute to ranula development.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0