International journal of oral and maxillofacial surgery最新文献

Correlation between condylar repositioning, resorption, and mandibular relapse post-orthognathic surgery with the straight locking miniplate technique in patients with Class II and III malocclusion: a retrospective study.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-14 DOI: 10.1016/j.ijom.2025.02.002

H Umezawa, H Takasu, T Ohya, Y Yamashita, M Hirota, K Mitsudo

{"title":"Correlation between condylar repositioning, resorption, and mandibular relapse post-orthognathic surgery with the straight locking miniplate technique in patients with Class II and III malocclusion: a retrospective study.","authors":"H Umezawa, H Takasu, T Ohya, Y Yamashita, M Hirota, K Mitsudo","doi":"10.1016/j.ijom.2025.02.002","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.02.002","url":null,"abstract":"This study investigated the relationship between condylar position, condylar volume, and mandibular relapse following orthognathic surgery in which the proximal segments were temporarily fixed with a positioning device to maintain the condylar position. Computed tomography data (pre-surgery, immediately post-surgery, and 1 year post-surgery) from 12 patients with Class II malocclusion and 20 with Class III were analysed. Condylar volume was significantly lower in Class II patients than in Class III patients at all time-points (P < 0.001), and only Class II patients showed a significant volume reduction from immediately post-surgery to 1 year post-surgery (P < 0.001). Three-dimensional condylar movements from pre-surgery to immediately post-surgery and from pre-surgery to 1 year post-surgery were significantly greater in Class II patients than in Class III patients (both P < 0.001). Additionally, Class II patients exhibited more restoration movements to the preoperative position from immediately post-surgery to 1 year post-surgery, correlating with the volume reduction (r = -0.53, P = 0.007), which in turn correlated significantly with mandibular relapse (r = 0.63, P < 0.001). These findings suggest an association between preoperative volume, intraoperative movement, condyle movement restoration, volume reduction, and postoperative mandibular relapse, particularly in the Class II group. Accurate condylar positioning appears crucial for mitigating mandibular relapse in Class II cases.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of chlorhexidine, povidone-iodine, and hydrogen peroxide irrigation on pain and swelling after mandibular third molar surgery: randomized controlled trial.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-13 DOI: 10.1016/j.ijom.2025.01.021

M Shahraki, A H Khazaei, S Hakimi, M Hasheminasab, S A Haradasht

{"title":"Effect of chlorhexidine, povidone-iodine, and hydrogen peroxide irrigation on pain and swelling after mandibular third molar surgery: randomized controlled trial.","authors":"M Shahraki, A H Khazaei, S Hakimi, M Hasheminasab, S A Haradasht","doi":"10.1016/j.ijom.2025.01.021","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.021","url":null,"abstract":"The objective of this study was to compare the effects of irrigation solutions containing chlorhexidine, povidone-iodine, or hydrogen peroxide on pain and swelling following mandibular third molar surgery. This prospective randomized controlled trial employed a single-blind design. Overall, 112 patients were randomized to four groups based on the antiseptic assigned for the intervention: control, chlorhexidine (CHX), povidone-iodine (PI), and hydrogen peroxide (HP). The patients were followed up on days 1, 3, 7, and 15 after surgery, and pain and swelling were assessed. Data were analysed using ANOVA and post hoc multiple comparison tests. The CHX and HP groups demonstrated significantly lower mean pain scores compared to the control group on days 3 (P = 0.021, P = 0.033) and 7 (P = 0.002, P = 0.017). Regarding the difference in swelling from baseline (before surgery) on each follow-up day, the CHX and HP groups showed significantly less swelling compared to the control group on days 1 (P = 0.023, P = 0.012), 3 (P = 0.007, P = 0.001), and 7 (P = 0.002, P = 0.018). Moreover, the CHX and HP groups demonstrated significantly lower mean swelling changes from baseline compared to PI: CHX vs PI on day 7 (P = 0.032), HP vs PI on day 1 (P = 0.037). In conclusion, chlorhexidine and hydrogen peroxide solutions are highly beneficial options for socket irrigation following mandibular third molar surgery. This study showed a more prominent reduction in pain and swelling with chlorhexidine and hydrogen peroxide solutions compared to povidone-iodine solution.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes of open treatment of condylar head fractures using cannulated headless bone screws-a retrospective analysis.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-13 DOI: 10.1016/j.ijom.2025.01.018

A Franke, J B Matschke, P Sembdner, A Seidler, N M H McLeod, H Leonhardt

{"title":"Long-term outcomes of open treatment of condylar head fractures using cannulated headless bone screws-a retrospective analysis.","authors":"A Franke, J B Matschke, P Sembdner, A Seidler, N M H McLeod, H Leonhardt","doi":"10.1016/j.ijom.2025.01.018","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.018","url":null,"abstract":"The treatment of mandibular fractures affecting the condylar head (CHF) can be either closed or open. In the case of an open approach, the headless bone screw (HBS) is an option. This study was performed to investigate the efficacy of osteosynthesis with HBS using three-dimensional radiographic imaging and clinical evaluation over long-term follow-up. This was a single-centre retrospective study. Clinical parameters and three-dimensional radiographic scans were collected during follow-up, DICOM datasets were segmented, and model analysis was conducted. Forty-five patients who received a HBS and met the eligibility criteria were included. There were significant improvements in all clinical parameters (mouth opening, protrusion, laterotrusion; all P < 0.05) except for the laterotrusion of the unaffected side (P = 0.071). Mean volume and surface area changes (from postoperative (mean 1.9 days) to final follow-up (mean 1675 days)) were 127.2 mm3 and -22.4 mm2, respectively, and were not statistically significant (P = 0.18 and P = 0.51). There were radiographic signs of condylar remodelling. Nine HBS in nine patients required removal due to the screw penetrating the articular surface of the healing condylar head. This single-centre retrospective study found good functional outcomes using HBS for CHF, with a screw removal rate of 20%.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pretreatment nutritional indices are associated with survival and T-cell exhaustion in recurrent or metastatic oral squamous cell carcinoma patients treated with immune checkpoint inhibitors: a retrospective cohort study. 治疗前营养指数与接受免疫检查点抑制剂治疗的复发性或转移性口腔鳞状细胞癌患者的生存期和T细胞衰竭有关：一项回顾性队列研究。

International journal of oral and maxillofacial surgery Pub Date : 2025-02-11 DOI: 10.1016/j.ijom.2025.01.010

T Ooyama, M Hirayama, Y Seki, A Iwamoto, R Yoshida, H Nakayama

{"title":"Pretreatment nutritional indices are associated with survival and T-cell exhaustion in recurrent or metastatic oral squamous cell carcinoma patients treated with immune checkpoint inhibitors: a retrospective cohort study.","authors":"T Ooyama, M Hirayama, Y Seki, A Iwamoto, R Yoshida, H Nakayama","doi":"10.1016/j.ijom.2025.01.010","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.010","url":null,"abstract":"Pretreatment immune dynamics and nutritional status are important predictors of survival outcomes in various malignancies. This study was performed to evaluate the relationships between survival outcomes and the pretreatment nutritional indices - Onodera's prognostic nutritional index (OPNI) and neutrophil-to-lymphocyte ratio (NLR) - in 42 patients with recurrent or metastatic oral squamous cell carcinoma (OSCC) who underwent treatment with immune checkpoint inhibitors (ICI). Additionally, the relationships between these nutritional indices and T-cell exhaustion in the peripheral blood of the patients were analysed. As a result, the Kaplan-Meier method revealed that lower OPNI was significantly associated with poorer overall survival (OS) and progression-free survival (PFS) (both P < 0.001). Likewise, the results of the multivariate analysis showed that a low OPNI was independently associated with poor 5-year OS (hazard ratio 4.36, P = 0.008) and PFS (hazard ratio 4.04, P = 0.010). Patients with a low OPNI had a significantly higher frequency of PD-1+ CD8+ T-cells than those with a high OPNI (P = 0.009). These findings demonstrate that pretreatment OPNI is a valuable independent prognostic indicator of OS and PFS in OSCC patients following treatment with ICI. The OPNI might reflect T-cell exhaustion in the peripheral blood of OSCC patients.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to the comment on "Deep convolutional neural network for automatic segmentation and classification of jaw tumors in contrast-enhanced computed tomography images".

International journal of oral and maxillofacial surgery Pub Date : 2025-02-08 DOI: 10.1016/j.ijom.2025.01.019

K Warin, W Limprasert, T Paipongna, S Chaowchuen, S Vicharueang

引用次数: 0

Comment on: "Deep convolutional neural network for automatic segmentation and classification of jaw tumors in contrast-enhanced computed tomography images".

International journal of oral and maxillofacial surgery Pub Date : 2025-02-07 DOI: 10.1016/j.ijom.2025.01.020

C M Ardila, P K Yadalam

引用次数: 0

Clinical validation of the virtual splint registration workflow for craniomaxillofacial surgery.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-06 DOI: 10.1016/j.ijom.2025.01.014

J F Sabelis, R Schreurs, L Dubois, A G Becking

{"title":"Clinical validation of the virtual splint registration workflow for craniomaxillofacial surgery.","authors":"J F Sabelis, R Schreurs, L Dubois, A G Becking","doi":"10.1016/j.ijom.2025.01.014","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.014","url":null,"abstract":"Accurate registration is vital to transfer the virtual surgical plan during surgery. This study's goal was to present and clinically validate a virtual splint registration workflow. Ten dentate patients requiring revision surgery were included. Specific inclusion criterion for this study was the presence of at least two osteosynthesis screws on the orbital rim from a previous surgery. Dedicated orthognathic surgery software was used to fuse the maxillary dental scan with the computed tomography and generate a dental splint, which was imported into the navigation software and augmented with fiducial markers. Registration points were indicated virtually and the augmented splint was three-dimensionally printed. Intraoperatively, the splint was fitted on the maxillary dentition and the fiducial markers were used for registration. Accuracy of the registration procedure was quantified by calculating the difference between the landmarks acquired by indicating the pre-existing osteosynthesis material with the navigation pointer and in the virtual planning software. After acquisition of the landmarks, the screws were removed and surgery proceeded according to plan. A median target registration error of 1.53 mm was found. The advantages of the virtual splint registration workflow are that it does not require extensive computer-aided design skills or repeated preoperative imaging, and is non-invasive.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of computer-simulated mandibular autorotation following single-jaw maxillary repositioning surgery using customized surgical cutting guides and fixation plates.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-05 DOI: 10.1016/j.ijom.2025.01.017

C Vu, J K Hartsfield, A Mian, B Allan, D Gebauer, M Goonewardene

{"title":"Accuracy of computer-simulated mandibular autorotation following single-jaw maxillary repositioning surgery using customized surgical cutting guides and fixation plates.","authors":"C Vu, J K Hartsfield, A Mian, B Allan, D Gebauer, M Goonewardene","doi":"10.1016/j.ijom.2025.01.017","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.017","url":null,"abstract":"The literature on computer-aided surgical simulation (CASS) has focused extensively on the precision and accuracy of maxillary and mandibular repositioning surgery. However, the predictability of mandibular autorotation remains understudied. The aim of this study was to evaluate the accuracy of CASS-planned mandibular autorotation in 50 consecutive patients undergoing maxillary repositioning surgery with customized titanium surgical cutting guides and fixation plates. The study patients (32 male and 18 female, mean age 25 years for both sexes) underwent Le Fort I osteotomy, with or without simultaneous genioplasty were performed by one experienced maxillofacial surgeon. Preoperative and postoperative multi-slice computed tomography scans were superimposed and contrasted with the surgical plan to evaluate any discrepancies between the planned and observed mandibular positions after surgery. The translational movements of the maxilla were a median 0.38 mm transversely, mean -5.29 mm anteroposteriorly, and median -1.00 mm vertically. Using a computed mandibular centroid, the absolute linear and angular discrepancies between the planned and observed mandibular autorotation movements were found to be within the clinically significant thresholds of 1 mm and 2°, respectively. It is concluded that CASS-planned mandibular autorotation is predictable when maxillary down-grafting and impaction does not exceed 5 mm and 4 mm, respectively.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maxilla-first patient-specific osteosynthesis vs mandible-first bimaxillary orthognathic surgery using splints: a randomized controlled trial.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-04 DOI: 10.1016/j.ijom.2025.01.016

H van der Wel, R H Schepers, F Baan, F K L Spijkervet, J Jansma, J Kraeima

{"title":"Maxilla-first patient-specific osteosynthesis vs mandible-first bimaxillary orthognathic surgery using splints: a randomized controlled trial.","authors":"H van der Wel, R H Schepers, F Baan, F K L Spijkervet, J Jansma, J Kraeima","doi":"10.1016/j.ijom.2025.01.016","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.016","url":null,"abstract":"Patient-specific osteosynthesis plates and three-dimensional virtual surgical planning with patient-specific surgical guides have significantly advanced orthognathic surgery, enhancing surgical accuracy. This study compares the outcomes of the mandible-first approach using an intermediate splint and manually bent osteosynthesis plates with the maxilla-first approach utilizing patient-specific osteosynthesis fixation in bimaxillary orthognathic surgery. This multi-centre randomized controlled trial included 88 patients, with 77 completing the study. Patients were randomly assigned to either the 'mandible-first' group (mandible-first with an intermediate splint) or the 'maxilla-first with PSO' group (maxilla-first with patient-specific osteosynthesis). Postoperative evaluation using cone beam computed tomography images showed significantly lower deviations from the preoperative plan in the maxilla-first with PSO group compared to the mandible-first group, for anteroposterior (median 1.0 mm vs 1.8 mm, P = 0.008) and left/right translations (median 0.4 mm vs 0.8 mm, P = 0.003), and yaw rotation (median 0.5° vs 1.0°, P = 0.013). Regarding clinical accuracy (categorized as optimal, good, or suboptimal), 59.5% of the patients in the maxilla-first with PSO group had an optimal or good result compared to 17.5% in the mandible-first group. The study findings suggest the maxilla-first PSO approach offers enhanced accuracy, supporting its adoption in orthognathic surgery for better surgical outcomes.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Aloe vera in the treatment of oral mucositis: a systematic review and meta-analysis of randomized controlled trials.

International journal of oral and maxillofacial surgery Pub Date : 2025-02-04 DOI: 10.1016/j.ijom.2025.01.015

D Cássia-Santos, C K C Santos, L T Fernandes, G Q Carvalho, S N de Aquino, C A A Lemos

{"title":"Effectiveness of Aloe vera in the treatment of oral mucositis: a systematic review and meta-analysis of randomized controlled trials.","authors":"D Cássia-Santos, C K C Santos, L T Fernandes, G Q Carvalho, S N de Aquino, C A A Lemos","doi":"10.1016/j.ijom.2025.01.015","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.01.015","url":null,"abstract":"Oral mucositis (OM) is a common complication of cancer patients. A systematic review and meta-analysis assessed the effectiveness of Aloe vera (AV) in the treatment of OM. The population included cancer patients undergoing radiotherapy or chemotherapy, treated for OM with AV. A search following the PICOS strategy, with specific keywords, identified randomized controlled trials (RCTs) published up to September 2024. Seven RCTs involving 355 participants, 170 in the intervention (AV) groups (mean age 39.7 years, standard deviation 23.9 years) and 185 in control groups (mean age 39.0 years, standard deviation 23.5 years), were included. A significant difference in the improvement of severe mucositis cases (grades 3 and 4) was observed with the use of AV compared to control (placebo, sodium bicarbonate, or benzydamine) (odds ratio 0.32, 95% confidence interval 0.15-0.70, P = 0.004). Considering the moderate heterogeneity observed (I2 = 36%, P = 0.15), a subgroup analysis was conducted. A subgroup analysis showed significant improvement in grade 3 and 4 OM for AV versus placebo (odds ratio 0.22, 95% CI 0.11-0.44, P < 0.001), but not compared with sodium bicarbonate or benzydamine. The results suggest that AV may be beneficial for cancer patients undergoing radiotherapy or chemotherapy, leading to improvements in the more severe stages of OM.","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0