International journal of oral and maxillofacial surgery最新文献

筛选
英文 中文
Evaluation of post-surgical outcomes in mandibular asymmetry with three-dimensional cephalometric analysis. 三维头颅测量分析评价下颌不对称术后疗效。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-24 DOI: 10.1016/j.ijom.2025.06.016
L H Chan, Y Y Leung
{"title":"Evaluation of post-surgical outcomes in mandibular asymmetry with three-dimensional cephalometric analysis.","authors":"L H Chan, Y Y Leung","doi":"10.1016/j.ijom.2025.06.016","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.06.016","url":null,"abstract":"<p><p>Facial asymmetry is common among orthognathic patients, particularly in Southern Chinese populations. Mandibular asymmetry is a prominent manifestation of facial asymmetry and is frequently observed in skeletal Class III patients. Various three-dimensional (3D) imaging techniques, such as cone beam computed tomography (CBCT), are utilized to evaluate skeletal asymmetry. Orthognathic surgery is the definitive treatment for the correction of facial asymmetry; however, the positions of vital structures may constrain surgical access to certain anatomical regions, resulting in residual asymmetry. A 3D analysis - RBC cephalometric analysis - categorizes mandibular asymmetry based on a severity grading across three distinct anatomical regions: ramus (R), body (B), and chin (C). This analysis was applied to the data of 57 patients, and their preoperative and postoperative CBCT scans were compared. The findings indicated significant corrections in height at ramus and chin, while asymmetry in height and width at the mandible body could not be adequately corrected. No significant difference in the degree of mandibular asymmetry correction achieved was observed between intraoral vertical ramus osteotomy and sagittal split ramus osteotomy. Through the application of the RBC cephalometric analysis, this study identified and evaluated the limitations of orthognathic surgery in the context of asymmetry correction.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carbon impact of orthognathic surgery. 正颌手术对碳的影响。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-24 DOI: 10.1016/j.ijom.2025.06.005
L Mattei, F Barry, N Al-Badri, J Ferri, G Masson, R Nicot
{"title":"Carbon impact of orthognathic surgery.","authors":"L Mattei, F Barry, N Al-Badri, J Ferri, G Masson, R Nicot","doi":"10.1016/j.ijom.2025.06.005","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.06.005","url":null,"abstract":"<p><p>Climate change is a threat to humankind that cannot be ignored and requires efforts to be made in every sector, including the health care industry. Operating rooms are understood to contribute significantly to emissions. The aim of this study was to assess the carbon footprint of orthognathic surgery in a regional specialized centre at the University Hospital of Lille (CHU Lille) in France. All consecutive patients who underwent orthognathic surgery between January 2 and July 2, 2024 were included retrospectively. A life cycle assessment (LCA) of orthognathic surgery was performed to estimate its overall carbon footprint. Patient transportation, medical devices, patient consumables, the sterilization process, medications, operating room electricity consumption, operating room heating, anaesthetic gases, and consultations were included. Staff transportation, hospitalization, cleaning, reprocessing of linen, and water consumption were excluded. Overall, 122 patients underwent orthognathic surgery in CHU Lille during the study period. The mean ± standard deviation carbon emissions for orthognathic surgery was 209.00 ± 149.92 kgCO<sub>2</sub>eq. Patient transportation represented 66.4-70.4% of the overall emissions. Orthognathic surgery results in the emission of non-negligible amounts of carbon dioxide equivalent. The carbon footprint of other procedures requires evaluation, and actions need to be taken to reduce their impact.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal mandibular fractures: a scoping review. 新生儿下颌骨折:范围审查。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-24 DOI: 10.1016/j.ijom.2025.06.014
J H T Sng, Y Zhang, K Z Ong
{"title":"Neonatal mandibular fractures: a scoping review.","authors":"J H T Sng, Y Zhang, K Z Ong","doi":"10.1016/j.ijom.2025.06.014","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.06.014","url":null,"abstract":"<p><p>While uncommon, trauma-induced fractures to the neonatal mandible require unique consideration. A scoping review of neonatal mandibular fractures (NMF) was performed, in accordance with the PRISMA-ScR guidelines. The PubMed, Embase, Cochrane Library, Scopus, and Web of Science databases were comprehensively searched, covering the period 1990 to March 2025. All studies that reported NMF (age <28 days) were considered eligible. Due to the nature of the studies found, only a descriptive analysis was performed. Seven articles reporting seven cases of NMF were included. Four cases were birth trauma-induced; two of which were associated with forceps delivery and three were associated with an abnormal foetal position during labour. Various treatment modalities, complications, and durations of follow-up were reported. Open reduction was performed in four cases (no fixation, suture fixation, wire fixation, plate and screw fixation performed in one case each) and closed reduction in three (acrylic splint and circummandibular wiring in two, circummandibular wiring alone in one). More studies are needed to explore the association between NMF and birth trauma due to delivery methods and foetal position. Moreover, long term-follow up is required to establish possible implications of NMF and its management on the development of the dentition and facial growth.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunohistochemical expression of Ki67, CD10, BRAF, and α-SMA tumour markers in ameloblastoma and odontogenic keratocyst. Ki67、CD10、BRAF和α-SMA肿瘤标志物在成釉细胞瘤和牙源性角化囊肿中的免疫组织化学表达。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-23 DOI: 10.1016/j.ijom.2025.06.012
C Chen, T Taheri, M Batstone, N Johnson
{"title":"Immunohistochemical expression of Ki67, CD10, BRAF, and α-SMA tumour markers in ameloblastoma and odontogenic keratocyst.","authors":"C Chen, T Taheri, M Batstone, N Johnson","doi":"10.1016/j.ijom.2025.06.012","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.06.012","url":null,"abstract":"<p><p>Certain tumour markers may play a role in the pathogenesis of ameloblastoma and odontogenic keratocyst (OKC), and may aid the initial diagnostic assessment in selected cases, or possibly serve as prognostic indicators. An immunohistochemical (IHC) study was undertaken to observe the staining patterns of Ki67, CD10, BRAF, and α-SMA tumour biomarkers in relation to ameloblastoma and OKC. Patients treated for ameloblastoma or OKC at the Royal Brisbane and Women's Hospital between January 1, 2008 and December 31, 2020, inclusive, were included. Selected paraffin tissue blocks were retrieved, and slides underwent IHC staining for Ki67 and CD10 (both OKC and ameloblastoma cases) and for BRAF and α-SMA (ameloblastoma cases). Differences were observed in CD10 expression between lesions, with inflammation influencing increased expression in OKC, while unicystic ameloblastoma was usually CD10-positive (87.5%) regardless of inflammation. CD10 and BRAF demonstrated significant differences in location, both presenting higher in mandibular than maxillary ameloblastoma. The study findings suggest that some tumour markers may assist as diagnostic tools in odontogenic lesions; however, tumour marker expression did not demonstrate utility as a prognostic biomarker in ameloblastoma or OKC, where treatment decisions likely played a larger role in the risk of recurrence.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and dental implant outcomes in patients after mandibular continuity reconstruction with bone flaps versus bone grafts: a systematic review and meta-analysis. 骨瓣与骨移植物重建下颌连续性患者的临床和牙种植结果:系统回顾和荟萃分析。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-20 DOI: 10.1016/j.ijom.2025.06.011
B C Mendes, A M S Santos, M T V Rodrigues, J F Santiago Junior, E Hochuli-Vieira, L P Faverani
{"title":"Clinical and dental implant outcomes in patients after mandibular continuity reconstruction with bone flaps versus bone grafts: a systematic review and meta-analysis.","authors":"B C Mendes, A M S Santos, M T V Rodrigues, J F Santiago Junior, E Hochuli-Vieira, L P Faverani","doi":"10.1016/j.ijom.2025.06.011","DOIUrl":"10.1016/j.ijom.2025.06.011","url":null,"abstract":"<p><p>This study was performed to evaluate the failure and complication rates of bone flaps and bone grafts used for mandible reconstruction following partial mandible resection, and the failure and complication rates of implants installed in these grafts. A systematic review and meta-analysis was conducted following the PRISMA protocol. The level of evidence was assessed according to the National Health and Medical Research Council (Australia) classifications. Quantitative data for failures and complications were pooled and evaluated to determine the overall event rate with 95% confidence interval. Twenty-one studies (seven prospective, 14 retrospective) were identified, including 519 transplants: 423 bone flaps with 1428 implants, and 96 bone grafts with 322 implants. The overall mean event rate for graft failure was 3.5% for bone flaps and 4.6% for bone grafts, while the rate for complications was 9.9% for bone flaps and 10.5% for bone grafts. The mean event rate for implant failure was 5.5% for bone flaps and 9.9% for bone grafts. The mean event rate for implant complications was 5.9% for bone flaps; however, implant complications were absent in the bone grafts. Failure rates for both flaps and grafts were low, and complication rates were similar (P > 0.05). Implant survival did not differ significantly between the flaps and grafts (P > 0.05). The data must be interpreted with caution, as the studies evaluated had relatively small samples from which to draw comparisons.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of postoperative thickening of the sinus mucosa in cone beam computed tomography with decreased voxel brightness of the regenerated bone after sinus floor augmentation: a prospective study. 锥形束计算机断层扫描显示鼻窦黏膜术后增厚与窦底增强后再生骨体素亮度下降的相关性:一项前瞻性研究。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-20 DOI: 10.1016/j.ijom.2025.06.013
T Uematsu, K Ito, T Tsukioka, K Isobe, H Okudera, T Kaneda
{"title":"Correlation of postoperative thickening of the sinus mucosa in cone beam computed tomography with decreased voxel brightness of the regenerated bone after sinus floor augmentation: a prospective study.","authors":"T Uematsu, K Ito, T Tsukioka, K Isobe, H Okudera, T Kaneda","doi":"10.1016/j.ijom.2025.06.013","DOIUrl":"10.1016/j.ijom.2025.06.013","url":null,"abstract":"<p><p>Although postoperative thickening of the sinus membrane is a risk in maxillary sinus floor augmentation (MSFA), the relationship between postoperative mucosal thickening (MT) and the quality of the augmented bone has not been clarified. The aim of this study was to evaluate the characteristics of the augmented bone after MSFA using cone beam computed tomography (CBCT) histograms, comparing patients with and without postoperative maxillary sinus MT. Patients who underwent MSFA with beta-tricalcium phosphate and simultaneous implantation between 2021 and 2023 were included (14 regions in 12 patients). CBCT images obtained pre-surgery (C1) and at 6 months post-surgery (C2) were used for comparisons between a No-MT group (≤2 mm) and an MT group (>2 mm). Three-dimensional bone subtraction (C2 - C1) was performed for the analysis of voxel brightness and quantification of the augmented bone volume. Histogram analysis showed that the MT group had a significantly lower mean brightness value (P = 0.004) and higher skewness (P = 0.003) and kurtosis (P = 0.006) values than the No-MT group. Thus, histogram-based assessment of bone quality in MSFA may be used as a prognostic marker for implant success by monitoring changes in brightness, skewness, and kurtosis during the augmented bone healing process.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporary protective glossorrhaphy for controlling tongue size and position during intraoperative intermaxillary fixation in orthognathic surgery. 在正颌手术术中控制舌大小和位置的暂时性保护性舌语修复术。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-19 DOI: 10.1016/j.ijom.2025.06.008
E G F Dos Santos, A V Martins-de-Barros, T F Faro, F A da Costa Araújo
{"title":"Temporary protective glossorrhaphy for controlling tongue size and position during intraoperative intermaxillary fixation in orthognathic surgery.","authors":"E G F Dos Santos, A V Martins-de-Barros, T F Faro, F A da Costa Araújo","doi":"10.1016/j.ijom.2025.06.008","DOIUrl":"10.1016/j.ijom.2025.06.008","url":null,"abstract":"<p><p>This technical note introduces the protective glossorrhaphy as a method for repositioning the tongue during orthognathic surgery to maintain central alignment and prevent interference with occlusal splints. The procedure involves placing 2-0 cotton sutures at the level of the molars and canines, approximating the lateral borders of the tongue while preserving vascularization and function. The glossorrhaphy is maintained throughout the jaw repositioning stages and removed only after verifying the final occlusion. By temporarily approximating the lateral borders of the tongue with sutures, this technique aids in the accurate placement of the occlusal guide. The temporary glossorrhaphy offers a straightforward and effective solution, ensuring proper occlusal splint adaptation and reducing the risk of postoperative complications. This minimally invasive approach enhances outcomes in orthognathic surgery by addressing challenges related to tongue positioning.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features and management of odontogenic keratocysts in Gorlin-Goltz syndrome. Gorlin-Goltz综合征牙源性角化囊肿的临床特点及治疗。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-18 DOI: 10.1016/j.ijom.2025.06.009
J T W Li, C C J Wan, A W K Yeung, Y Y Leung, Y-X Su
{"title":"Clinical features and management of odontogenic keratocysts in Gorlin-Goltz syndrome.","authors":"J T W Li, C C J Wan, A W K Yeung, Y Y Leung, Y-X Su","doi":"10.1016/j.ijom.2025.06.009","DOIUrl":"10.1016/j.ijom.2025.06.009","url":null,"abstract":"<p><p>One of the frequent manifestations of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder, is the development of odontogenic keratocysts (OKCs). The aim of this study was to evaluate the efficacy and safety of treatment modalities for OKCs in GGS patients, and their corresponding recurrence/new lesion rates and complications. Twelve GGS patients (eight male, four female) with 36 OKCs were included. Common clinical features of GGS were calcification of the falx cerebri (eight patients, 66.7%), macrocephaly (seven patients, 58.3%), and frontal bossing (six patients, 50%). Enucleation with Carnoy's solution was the primary treatment for 10 patients, while two underwent marsupialization. The mean follow-up was 13.3 years. Nine (75%) of the patients did not experience any early complications (up to 1 month postoperative). The OKC recurrence/new lesion rate was 83.3% after surgical treatment (enucleation or marsupialization), with five patients (41.7%) experiencing two occurrences of OKCs during follow-up (range 2.7-29.9 years). Enucleation of OKCs with Carnoy's solution is a safe and effective approach in GGS patients. However, the high recurrence/new lesion rate underscores the need for close long-term monitoring for at least 7 years and consideration of more aggressive surgical methods in these patients.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of bovine versus porcine bone xenografts in maxillary sinus floor augmentation: a systematic review and meta-analysis. 牛与猪骨异种移植在上颌窦底增强中的比较评价:系统回顾和荟萃分析。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-18 DOI: 10.1016/j.ijom.2025.05.011
S Shi, Z Li, J Su, L He, J Guo, W Zhang
{"title":"Comparative evaluation of bovine versus porcine bone xenografts in maxillary sinus floor augmentation: a systematic review and meta-analysis.","authors":"S Shi, Z Li, J Su, L He, J Guo, W Zhang","doi":"10.1016/j.ijom.2025.05.011","DOIUrl":"10.1016/j.ijom.2025.05.011","url":null,"abstract":"<p><p>Deproteinized bovine bone mineral (DBBM) and deproteinized porcine bone mineral (DPBM) are two commercially available xenografts that may be used in maxillary sinus floor augmentation (MSFA). The aim of this study was to compare the efficacy of these two xenografts in MSFA. An electronic search (Embase, PubMed, Cochrane Central Register of Controlled Trials, and Web of Science) and manual search were conducted up until March 2025. Eligible randomized controlled trials (RCTs) were included in the analysis. The Cochrane risk of bias tool was used to evaluate the risk of bias in individual studies. Relevant data were extracted and meta-analyses performed whenever possible. Of the 707 studies identified in the search, six RCTs were included for analysis. Meta-analysis did not show any significant difference in the percentage of new bone formation between MSFA with DBBM and DPBM (mean difference -0.53, 95% confidence interval -1.64 to 0.58; P = 0.35), or in the proportion of residual bone graft (mean difference -2.35, 95% confidence interval -7.39 to 2.70; P = 0.36). However, DPBM tended to show increased resorption characteristics compared to DBBM. In conclusion, DPBM and DBBM showed similar new bone formation and residual graft particles when used for maxillary sinus floor augmentation.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicopathological study of invasion patterns and late cervical lymph node metastasis in pT1/T2 oral squamous cell carcinoma. pT1/T2口腔鳞状细胞癌侵袭模式及晚期颈部淋巴结转移的临床病理研究。
International journal of oral and maxillofacial surgery Pub Date : 2025-06-17 DOI: 10.1016/j.ijom.2025.06.010
Y Oikawa, M Fukuda, Y Noguchi, K Ito, H Igarashi, H Takano
{"title":"Clinicopathological study of invasion patterns and late cervical lymph node metastasis in pT1/T2 oral squamous cell carcinoma.","authors":"Y Oikawa, M Fukuda, Y Noguchi, K Ito, H Igarashi, H Takano","doi":"10.1016/j.ijom.2025.06.010","DOIUrl":"https://doi.org/10.1016/j.ijom.2025.06.010","url":null,"abstract":"<p><p>Despite early-stage oral squamous cell carcinoma (OSCC) often being treated effectively with surgery or radiation, 20-40% of patients develop late cervical lymph node metastasis (LCLM), significantly impacting survival rates. This clinicopathological study was performed to investigate the association between invasion patterns and LCLM with pT1/T2 OSCC, treated surgically without preoperative chemotherapy or radiation; 145 patients were included, of whom 21 developed LCLM. Various histopathological factors were analysed, including depth of invasion (DOI), grade, pattern of invasion (POI), and the Yamamoto-Kohama classification. Multivariable analysis revealed that grade and POI were independent prognostic factors for LCLM; higher grade (hazard ratio 3.49, P = 0.043) and POI (hazard ratio 9.35, P = 0.007) were associated with an increased metastasis risk. Notably, 88.9% of cases with worst pattern of invasion-5 (WPOI-5) demonstrated LCLM. The study suggests that a combination of POI and grade should be considered for more accurate prediction and management of the LCLM risk, potentially guiding decisions on elective neck dissection to improve patient outcomes. However, WPOI-5 is difficult to identify from biopsy specimens, highlighting the need for a comprehensive approach combining multiple factors to accurately identify cases with a poor prognosis.</p>","PeriodicalId":94053,"journal":{"name":"International journal of oral and maxillofacial surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144328224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信