International journal of laboratory hematology最新文献

筛选
英文 中文
The PNH French Working Group Experience: Building a Strong Network of Cytometrists. PNH法国工作组经验:建立一个强大的细胞学家网络。
International journal of laboratory hematology Pub Date : 2025-02-25 DOI: 10.1111/ijlh.14449
Orianne Wagner-Ballon, Magali Le Garff-Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis
{"title":"The PNH French Working Group Experience: Building a Strong Network of Cytometrists.","authors":"Orianne Wagner-Ballon, Magali Le Garff-Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis","doi":"10.1111/ijlh.14449","DOIUrl":"https://doi.org/10.1111/ijlh.14449","url":null,"abstract":"<p><strong>Introduction: </strong>The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations.</p><p><strong>Methods: </strong>Thirty-five French and Belgian laboratories equipped with 2- or 3-laser cytometers applied three different panels with or without FLAER reagent in 305 samples. This multicenter study demonstrated the interplatform applicability of setting harmonization and the benefits of using a harmonized gating method. A 10<sup>-4</sup> limit of detection was achieved with harmonized multiparametric approaches in both six-color combinations, as well as a robust quantification of minor PNH clones.</p><p><strong>Results: </strong>Following this workshop, the group has developed a quality control scheme since 2013 to improve PNH diagnosis practices. This annual program includes two surveys, a virtual one and one based on fresh whole-blood sample analysis. Over the last 10 years, the regular participation of the French-speaking registered centers has demonstrated their strong commitment to our program, which offers various PNH clinical situations. Alongside, the conformity of the final reports provided by the participants has increased to 96%.</p><p><strong>Conclusion: </strong>In 2016, our PNH working group initiated a nationwide multicenter prospective observational study, collecting all PNH cases or GPI-deficient cells above 0.01% to monitor the long-term evolution of minor PNH clones < 1% and to further investigate the relevance of classifying type II and type III PNH cells in WBCs in clones > 1%. The strong network of cytometrists built led us to create in 2018 the French-speaking flow cytometry association in Hematology, namely CytHem, to harmonize the diagnostic practices in various hematological diseases.</p>","PeriodicalId":94050,"journal":{"name":"International journal of laboratory hematology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Update on the Activities of the International Society for Laboratory Hematology, 2025. 2025 年国际血液化验协会活动的最新情况。
International journal of laboratory hematology Pub Date : 2025-02-20 DOI: 10.1111/ijlh.14446
John L Frater, Tracy I George
{"title":"An Update on the Activities of the International Society for Laboratory Hematology, 2025.","authors":"John L Frater, Tracy I George","doi":"10.1111/ijlh.14446","DOIUrl":"https://doi.org/10.1111/ijlh.14446","url":null,"abstract":"","PeriodicalId":94050,"journal":{"name":"International journal of laboratory hematology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信