Hand surgery & rehabilitation最新文献

{"title":"Morphometric and curvature CT-based study of the distal radius watershed line.","authors":"Thomas Valerio, Elise Lupon, Alexandre Quemener-Tanguy, Eloïse Masse, Camille Brenac, Jean-Baptiste de Villeneuve Bargemon","doi":"10.1016/j.hansur.2025.102168","DOIUrl":"10.1016/j.hansur.2025.102168","url":null,"abstract":"<p><strong>Purpose: </strong>Fixation of distal radius fractures involving the volar rim is technically demanding and often complex. In most cases, it requires the use of so-called \"specific\" plates. Although these plates have been developed using morphometric databases, proper application can still be imperfect-even when the plate appears to be correctly positioned. This mismatch may result in secondary displacement of the fragment, tendon irritation, or even tendon rupture. We hypothesized that anatomical variations in the radius, particularly in the shape of the watershed line, may explain the difficulty in achieving optimal plate adaptation in some patients.</p><p><strong>Methods: </strong>Nineteen distal radius were analyzed using Computed Tomography-scan segmentation and curvature analysis to assess the shape of the watershed line. K-means clustering was then performed to identify distinct groups based on volar rim curvature patterns.</p><p><strong>Results: </strong>Clustering analysis revealed two distinct anatomical groups based on volar rim curvature. The first group exhibited a mean curvature of 0.07 ± 0.03 mm^-¹, while the second group had a significantly higher curvature of 0.23 ± 0.06 mm^-¹ (mean ± SD). A Student's t-test confirmed a statistically significant difference between the two groups (p < 0.001).</p><p><strong>Conclusions: </strong>Our findings suggest the existence of at least two anatomical variations in volar rim shape at the watershed line, forming a spectrum between flatter and more sharply curved forms. These anatomical differences may explain inconsistencies in plate adaptation and should be taken into account by surgeons when selecting and positioning fixation hardware.</p><p><strong>Level of evidence: </strong>Diagnostic study (IIIb).</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102168"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A progressive learning strategy for flexor tendon repair for young surgeons.","authors":"Nicolas Bigorre, Thomas Daoulas","doi":"10.1016/j.hansur.2025.102173","DOIUrl":"10.1016/j.hansur.2025.102173","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102173"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative factors that impact survey response rate two years after hand and wrist surgery: A retrospective study.","authors":"Matthew A Moshyedi, Samir Kaveeshwar, Brandon Leon, Nichole M Shaw, Matheus B Schneider, Ugo Udogwu, Evan L Honig, Michael A McCurdy, Raymond A Pensy, Christopher G Langhammer, R Frank Henn","doi":"10.1016/j.hansur.2025.102171","DOIUrl":"10.1016/j.hansur.2025.102171","url":null,"abstract":"<p><strong>Background: </strong>As patient-reported outcomes (PROs) become increasingly valuable, it is important to identify factors related to PRO survey nonresponse. The purpose of this study was to investigate preoperative factors associated with survey response rates two years after hand and wrist surgery.</p><p><strong>Methods: </strong>Patients enrolled in a surgical registry were administered an electronic survey at baseline and two years after hand and wrist surgery. Questionnaires included demographics, six Patient-Reported Outcomes Information System (PROMIS) domains, Numeric Pain Scales (NPS), Brief Michigan Hand Questionnaire (BMHQ), and Musculoskeletal Outcomes Data Evaluation and Management System (MODEMS) expectations domain. Patients who responded to the 2-year survey were compared to the patients who did not complete any of the 2-year survey.</p><p><strong>Results: </strong>There were 361 patients who completed the baseline survey and 253 patients (70%) completed the 2-year postoperative survey. Survey nonresponse was associated with younger age, less education, being unmarried, lower income, smoking, alcohol use, injury prior to surgery, worse PROMIS Social Satisfaction, worse PROMIS Pain Interference, worse PROMIS Anxiety, worse NPS joint score, worse BMHQ score, and lower treatment expectations. Multivariable logistic regression analysis confirmed that older age, better baseline BMHQ scores, greater treatment expectations and drinking alcohol 1-4 times per month were independent predictors of increased survey response rate.</p><p><strong>Conclusion: </strong>This study identified multiple socio-demographic and patient-reported factors related to survey nonresponse two years after hand and wrist surgery. These findings may guide targeted strategies to improve long-term survey response rates following hand and wrist surgery.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102171"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface replacing proximal interphalangeal joint arthroplasty in patients with post-traumatic versus primary osteoarthritis.","authors":"Helen Richter, Miriam Marks, Kei Mathis, Daniel B Herren, Stephan Schindele","doi":"10.1016/j.hansur.2025.102172","DOIUrl":"10.1016/j.hansur.2025.102172","url":null,"abstract":"<p><strong>Objective: </strong>The study compared clinical and patient-reported outcomes after proximal interphalangeal (PIP) joint surface replacement in patients with post-traumatic osteoarthritis (OA) and primary OA.</p><p><strong>Methods: </strong>Data from a prospective registry of patients who underwent surface replacing PIP joint arthroplasty (CapFlex-PIP, KLS Martin, Germany) were analysed. The primary outcome was active range of motion (ROM) measured before surgery and at several times up to five years after surgery. Grip strength, the brief Michigan Hand Outcomes Questionnaire (MHQ) and pain during daily activities were also assessed. Using propensity score matching, 22 patients with post-traumatic OA were matched to 110 patients with primary OA based on their preoperative (baseline) ROM. Between-group differences were analysed using the Mann-Whitney U test or Fisher's exact test.</p><p><strong>Results: </strong>After matching, the mean baseline ROM of 34° (95% confidence interval [CI]: 22 to 46) for post-traumatic OA patients and 38° (CI: 34 to 42) for primary OA patients were comparable. By one year, ROM improved significantly after PIP arthroplasty to 53° (CI: 45 to 61) and 59° (CI: 55 to 63) for post-traumatic and primary OA patients respectively, and there was no significant difference between groups (p = 0.103). Thereafter, ROM declined in a similar manner for both groups over the 5-year follow-up period. The brief MHQ score and grip strength at baseline and the 1-year follow-up were significantly higher in the post-traumatic OA group. Complications occurred in five post-traumatic OA patients (23%) and in 15 patients (14%) with primary OA (p = 0.327).</p><p><strong>Conclusion: </strong>Proximal interphalangeal joint surface replacement arthroplasty for post-traumatic osteoarthritis significantly improved range of motion, and this trend was similar to that achieved for patients with primary osteoarthritis. As clinical and patient-reported outcomes also improved, we recommend this procedure for patients with post-traumatic osteoarthritis, but the potentially higher risk of complications and reoperations for post-traumatic osteoarthritis patients should be considered.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102172"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential CpG methylation at <i>Nnat</i> in the early establishment of beta cell heterogeneity.","authors":"Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S Varghese, Pauline Chabosseau, Sayed M Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J Withers, Guy A Rutter, Steven J Millership","doi":"10.1101/2023.02.04.527050","DOIUrl":"10.1101/2023.02.04.527050","url":null,"abstract":"<p><strong>Aims/hypothesis: </strong>Beta cells within the pancreatic islet represent a heterogenous population wherein individual sub-groups of cells make distinct contributions to the overall control of insulin secretion. These include a subpopulation of highly-connected 'hub' cells, important for the propagation of intercellular Ca²⁺ waves. Functional subpopulations have also been demonstrated in human beta cells, with an altered subtype distribution apparent in type 2 diabetes. At present, the molecular mechanisms through which beta cell hierarchy is established are poorly understood. Changes at the level of the epigenome provide one such possibility which we explore here by focussing on the imprinted gene neuronatin (<i>Nnat</i>), which is required for normal insulin synthesis and secretion.</p><p><strong>Methods: </strong>Single cell RNA-seq datasets were examined using Seurat 4.0 and ClusterProfiler running under R. Transgenic mice expressing eGFP under the control of the <i>Nnat</i> enhancer/promoter regions were generated for fluorescence-activated cell (FAC) sorting of beta cells and downstream analysis of CpG methylation by bisulphite and RNA sequencing, respectively. Animals deleted for the de novo methyltransferase, DNMT3A from the pancreatic progenitor stage were used to explore control of promoter methylation. Proteomics was performed using affinity purification mass spectrometry and Ca²⁺ dynamics explored by rapid confocal imaging of Cal-520 and Cal-590. Insulin secretion was measured using Homogeneous Time Resolved Fluorescence Imaging.</p><p><strong>Results: </strong><i>Nnat</i> mRNA was differentially expressed in a discrete beta cell population in a developmental stage- and DNA methylation (DNMT3A)-dependent manner. Thus, pseudo-time analysis of embryonic data sets demonstrated the early establishment of <i>Nnat</i>-positive and negative subpopulations during embryogenesis. NNAT expression is also restricted to a subset of beta cells across the human islet that is maintained throughout adult life. NNAT⁺ beta cells also displayed a discrete transcriptome at adult stages, representing a sub-population specialised for insulin production, reminiscent of recently-described \"β_HI\" cells and were diminished in <i>db/db</i> mice. 'Hub' cells were less abundant in the NNAT⁺ population, consistent with epigenetic control of this functional specialization.</p><p><strong>Conclusions/interpretation: </strong>These findings demonstrate that differential DNA methylation at <i>Nnat</i> represents a novel means through which beta cell heterogeneity is established during development. We therefore hypothesise that changes in methylation at this locus may thus contribute to a loss of beta cell hierarchy and connectivity, potentially contributing to defective insulin secretion in some forms of diabetes.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10705251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82487063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of the mallet fracture: Open or percutaneous procedure?","authors":"G. Caruso, Laura Martini, S. Sargenti, A. Vitali","doi":"10.1016/j.hansur.2022.09.102","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.102","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43226124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intérêt de l’arthroscopie du poignet dans la prise en charge du syndrome d’Essex Lopresti au stade aigu","authors":"G. Herzberg, M. Burnier, Lyliane Ly","doi":"10.1016/j.hansur.2022.09.110","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.110","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41610827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conception d’une prothèse de pouce mixte, thermoformée et impression 3D pour les patients amputés","authors":"V. Oca, Maxime Debailleul, Charles Hustin, P. Duriez, d’Almeida Marc-Antoine, P. Laronde","doi":"10.1016/j.hansur.2022.09.233","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.233","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45250410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparaison de l’auto-évaluation et évaluation dans l’apprentissage de la microchirurgie: Une étude rétrospective comparative dans une cohorte d’étudiants en microchirurgie","authors":"J. Brunet, A. Petit, J. Jeudy, E. Maugendre, Y. S. Cast, N. Bigorre","doi":"10.1016/j.hansur.2022.09.152","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.152","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48023535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enucléation antéro-médiale du scaphoïde carpien sur une fracture luxation trans stylo-rétrolunaire: A propos d’un cas","authors":"M. Boukredera, M. Khenfri, A. Benhabiles","doi":"10.1016/j.hansur.2022.09.185","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.185","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47138673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}