Diabetes carePub Date : 2026-10-20DOI: 10.2337/dci26-0134
Maria J Redondo, Dave Cuthbertson, Raquel Gupta, Alejandro F Siller, Sridevi Devaraj, Kendra Vehik, Heba M Ismail, Ashok Balasubramanyam
{"title":"Response to Comment on Redondo et al. BMI Normalization Is Associated With Lower Risk of Progression to Type 1 Diabetes, Primarily in Youth.","authors":"Maria J Redondo, Dave Cuthbertson, Raquel Gupta, Alejandro F Siller, Sridevi Devaraj, Kendra Vehik, Heba M Ismail, Ashok Balasubramanyam","doi":"10.2337/dci26-0134","DOIUrl":"https://doi.org/10.2337/dci26-0134","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dc26-1159
Elizabeth Selvin, Valerie Sullivan, Hsin-Chieh Yeh, Michael Fang, Scott Pilla, Christine Mitchell, Lawrence Appel, Casey Rebholz
{"title":"A Recipe for Better Diabetes Management: The DASH4D Dietary Pattern.","authors":"Elizabeth Selvin, Valerie Sullivan, Hsin-Chieh Yeh, Michael Fang, Scott Pilla, Christine Mitchell, Lawrence Appel, Casey Rebholz","doi":"10.2337/dc26-1159","DOIUrl":"https://doi.org/10.2337/dc26-1159","url":null,"abstract":"<p><p>The 2026 American Diabetes Association \"Standards of Care in Diabetes\" includes extensive nutrition recommendations for people with diabetes but stops short of recommending a specific dietary pattern. Instead, the guidelines recommend that all patients be referred for individualized nutrition therapy. This approach appropriately acknowledges diverse patient needs; however, it is difficult for providers to deliver any form of individualized dietary guidance without a clear starting point to guide them. In this article we examine the tension between the needs for individualization and evidence-based nutritional standards in diabetes care. We argue that the DASH (Dietary Approaches to Stop Hypertension) dietary pattern stands out as being supported by decades of evidence from rigorous randomized clinical trials, meta-analyses, and large observational studies that have established its benefit for cardiovascular health. We summarize the recently completed DASH for Diabetes (DASH4D) trial, which demonstrated that a modified version of the original DASH eating plan, adapted for adults with diabetes, significantly reduced blood pressure and improved glycemic control in participants with type 2 diabetes and hypertension. We conclude that while individualized dietary counseling remains the standard of care, the DASH4D diet should be a recommended diet for patients with diabetes.</p>","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dc26-1754
Sevtap Kılınç
{"title":"Comment on Redondo et al. BMI Normalization Is Associated With Lower Risk of Progression to Type 1 Diabetes, Primarily in Youth.","authors":"Sevtap Kılınç","doi":"10.2337/dc26-1754","DOIUrl":"https://doi.org/10.2337/dc26-1754","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dc26-0199
Ehtasham Ahmad, Sarah Dib, Danielle Jones, Linda M Oude Griep, Roy Taylor, Laura C Kusinski, Claire L Meek
{"title":"Low-Carbohydrate Diets, Nutritional Adequacy, Glycemia, and Perinatal Outcomes in Women With Gestational Diabetes Mellitus: A Secondary Analysis of the DiGest Trial.","authors":"Ehtasham Ahmad, Sarah Dib, Danielle Jones, Linda M Oude Griep, Roy Taylor, Laura C Kusinski, Claire L Meek","doi":"10.2337/dc26-0199","DOIUrl":"https://doi.org/10.2337/dc26-0199","url":null,"abstract":"<p><strong>Objective: </strong>The optimal dietary carbohydrate intake for pregnant women is disputed internationally. Many authorities recommend a minimum of 175 g/day of carbohydrates primarily to support maternal brain glucose requirements and normal fetal brain development. We assessed whether low (<175 g/day) or very low (<120 g/day) carbohydrate intake was associated with altered nutrient intake, glycemia, or pregnancy outcomes in women with gestational diabetes mellitus (GDM).</p><p><strong>Research design and methods: </strong>Women recruited to the Dietary Intervention in Gestational Diabetes Trial (DiGest) completed masked continuous glucose monitoring and a 24-h dietary recall at baseline before random assignment to receive either a standard- (2,000 kcal/day) or reduced-energy diet (1,200 kcal/day) from ∼29-36 weeks' gestation.</p><p><strong>Results: </strong>At baseline, 215 women completed a dietary assessment, of whom 66 (30.7%), 74 (34.4%), and 75 (34.9%) reported standard (≥175 g/day), low (120-175 g/day), and very low carbohydrate intake (<120 g/day), respectively. Women consuming fewer carbohydrates consumed less energy, less dietary fiber, and fewer vitamins (B and E) and minerals but proportionally more protein and fat. Consumption of <120 g/day carbohydrates as assessed at baseline before the intervention was associated with a lower time above range (TAR) >120 mg/dL (-6.8% [95% CI -13.4% to -0.2%]; P = 0.044) and lower birth weight (-9.6 [95% CI -18.7 to -0.6] centiles; P = 0.037), but no difference in large- or small-for-gestational-age birth weight was observed. Low carbohydrate intake as a proportion of total energy intake (<35%) without energy restriction was associated with reduced TAR but not with a difference in birth weight.</p><p><strong>Conclusions: </strong>Lower carbohydrate intake at baseline was associated with modestly improved glycemia before random assignment in women with GDM, but vigilance to maintain adequate intake of micronutrients and fiber is required.</p>","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dc26-1761
Man Sun, Dan Zang, Jun Chen
{"title":"Comment on Redondo et al. BMI Normalization Is Associated With Lower Risk of Progression to Type 1 Diabetes, Primarily in Youth.","authors":"Man Sun, Dan Zang, Jun Chen","doi":"10.2337/dc26-1761","DOIUrl":"https://doi.org/10.2337/dc26-1761","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dc26-1070
Donald C Simonson, David E Cummings, Philip R Schauer, Ali Aminian, Bo Hu, David E Arterburn, John M Jakicic, Sangeeta R Kashyap, Ashley H Vernon, William F Gourash, Anita P Courcoulas, Mary Elizabeth Patti, John P Kirwan
{"title":"Predictors of Type 2 Diabetes Remission and Relapse After Metabolic-Bariatric Surgery or Medical-Lifestyle Therapy in the ARMMS-T2D Study.","authors":"Donald C Simonson, David E Cummings, Philip R Schauer, Ali Aminian, Bo Hu, David E Arterburn, John M Jakicic, Sangeeta R Kashyap, Ashley H Vernon, William F Gourash, Anita P Courcoulas, Mary Elizabeth Patti, John P Kirwan","doi":"10.2337/dc26-1070","DOIUrl":"https://doi.org/10.2337/dc26-1070","url":null,"abstract":"<p><strong>Objective: </strong>Metabolic-bariatric surgery (MBS) is effective in promoting remission of type 2 diabetes, but this outcome is not universally achieved. We identified baseline patient characteristics that predict diabetes remission and subsequent relapse after various MBS procedures versus intensive medical-lifestyle intervention.</p><p><strong>Research design and methods: </strong>Alliance of Randomized Trials of Medicine vs. Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) is a 14-year, multicenter study of health outcomes in 262 patients with type 2 diabetes (68% women, age 49.9 ± 8.3 years, BMI 36.4 ± 3.5 kg/m2, HbA1c 8.5 ± 1.5%) previously randomized to MBS (n = 166) or medical-lifestyle management (n = 96). Predictors of remission (defined as HbA1c <6.5% on no glucose-lowering medications) and relapse were determined using univariate time-to-event analyses of prespecified candidate predictors plus agnostic, multivariate least absolute shrinkage and selection operator.</p><p><strong>Results: </strong>Throughout a median of 11 years (maximum 14 years) of follow-up, 58% of participants randomized to MBS achieved diabetes remission versus 3% with medical-lifestyle management. Predictors of diabetes remission in univariate analyses included shorter diabetes duration, no insulin use, fewer glucose-lowering medication classes used, greater body weight, higher fasting C-peptide and insulin levels, and weight loss at 1 year (all P < 0.05). Diabetes remission predictors in multivariate analyses included baseline diabetes duration, insulin use, and weight change at 1 year (all P < 0.01). Diabetes relapse after initial remission in the MBS group was predicted by longer baseline diabetes duration and greater number of glucose-lowering medication classes used.</p><p><strong>Conclusions: </strong>Baseline predictors of diabetes remission and subsequent relapse among participants randomized to one of three MBS procedures or a medical-lifestyle intervention should help inform personalized selection of diabetes treatment.</p>","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-20DOI: 10.2337/dci26-0050
Ashok A Ganeshalingam, Nicolai Uhrenholt, Niels Bilenberg, Jan Frystyk
{"title":"Response to Comment on Ganeshalingam et al. Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.","authors":"Ashok A Ganeshalingam, Nicolai Uhrenholt, Niels Bilenberg, Jan Frystyk","doi":"10.2337/dci26-0050","DOIUrl":"https://doi.org/10.2337/dci26-0050","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-19DOI: 10.2337/dc26-1977
Sharleen L O'Reilly, Shelley Wilkinson, Jeannette M Beasley
{"title":"Comment on Qiang et al. The Effectiveness of Diabetes Prevention Programs Delivered in Primary Care for Individuals With Prediabetes or at Risk of Developing Type 2 Diabetes: A Systematic Review and Meta-analysis.","authors":"Sharleen L O'Reilly, Shelley Wilkinson, Jeannette M Beasley","doi":"10.2337/dc26-1977","DOIUrl":"https://doi.org/10.2337/dc26-1977","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-19DOI: 10.2337/dc26-2216
Feng Yu, Yuhuai Wu
{"title":"Comment on Johnsen et al. Achieving at Least 15% Weight Loss Within 2 Years of Type 2 Diabetes Diagnosis Is Associated With Lower Risks of Macrovascular and Microvascular Complications: A U.K. Cohort Study.","authors":"Feng Yu, Yuhuai Wu","doi":"10.2337/dc26-2216","DOIUrl":"https://doi.org/10.2337/dc26-2216","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes carePub Date : 2026-10-09DOI: 10.2337/dc26-1932
John F Mulley
{"title":"Continuous Glucose Monitoring Studies Should Not Be Exempt From the Reproducibility Revolution.","authors":"John F Mulley","doi":"10.2337/dc26-1932","DOIUrl":"https://doi.org/10.2337/dc26-1932","url":null,"abstract":"","PeriodicalId":93979,"journal":{"name":"Diabetes care","volume":" ","pages":""},"PeriodicalIF":16.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}