Chemosphere最新文献_第2页

A high-efficient electrochemical degradation of diclofenac in water on planar and microstructured 2D, and macroporous 3D boron-doped diamond electrodes: Identification of degradation and transformation products.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.144000

Erika Mordacikova, Marian Marton, Lucia Hojova, Gabriela Kuchtova, Katerina Grabicova, Pavol Michniak, Tomáš Mackul'ak, Roman Grabic, Marian Vojs, Andrea Vojs Stanova

{"title":"A high-efficient electrochemical degradation of diclofenac in water on planar and microstructured 2D, and macroporous 3D boron-doped diamond electrodes: Identification of degradation and transformation products.","authors":"Erika Mordacikova, Marian Marton, Lucia Hojova, Gabriela Kuchtova, Katerina Grabicova, Pavol Michniak, Tomáš Mackul'ak, Roman Grabic, Marian Vojs, Andrea Vojs Stanova","doi":"10.1016/j.chemosphere.2024.144000","DOIUrl":"https://doi.org/10.1016/j.chemosphere.2024.144000","url":null,"abstract":"The highly efficient degradation of persistent organic substances by electrochemical advanced oxidation processes (EAOPs), which don't result in the formation of potentially harmful by-products, is crucial for the future of water management. In this study, boron-doped diamond electrodes (BDDE) with three morphologies (planar 2D, microstructured 2D, and macroporous 3D) were employed for the anodic oxidation of diclofenac (DCF) in two working electrolytes (NaCl and Na2SO4). In total, 11 by-products formed during the electrochemical oxidation of DCF were identified via HPLC-HRMS. The identification of degradation products revealed the formation of various active chlorinated species. The utilization of a chlorine-free Na2SO4 electrolyte resulted in the formation of greater number of chlorinated species, while their elimination required a longer period compared to the use of NaCl electrolyte. The formation of by-products was also influenced by the specific type of BDD electrode, which was associated with variations in applied current density. This led to an uneven distribution of dichloro (2D BDDE) and trichloro (3D BDDE) patterns. However, none of the products showed signs of a high level of persistence. The results revealed that the type of electrolyte is the most significant factor affecting the removal efficiency of DCF, while the different electrode morphologies do not lead to differences in the removal rates. The electrode type exerted a notable influence on the removal rates, which was associated with varying applied current densities, exclusively in the case of the Na₂SO₄ electrolyte. Over 99 % removal efficiency for DCF in NaCl, with power consumption of 1.8 kWh m-3 was achieved.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"144000"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immobilization of phosphorus (P) migrated from sediment increasing algal-available P pool in P-inactivating material.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143976

Chengxun Deng, Ziyi Li, Qiannan Shang, Jutao Liu, Xinyuan Liu, Xiaowei Liu, Changhui Wang

{"title":"Immobilization of phosphorus (P) migrated from sediment increasing algal-available P pool in P-inactivating material.","authors":"Chengxun Deng, Ziyi Li, Qiannan Shang, Jutao Liu, Xinyuan Liu, Xiaowei Liu, Changhui Wang","doi":"10.1016/j.chemosphere.2024.143976","DOIUrl":"10.1016/j.chemosphere.2024.143976","url":null,"abstract":"Use of phosphorus (P)-inactivating material to immobilize P released from sediment, typically under anoxic condition, is a method often considered to reduce lake internal P loading for eutrophication control. This study found that immobilizing the released P from sediment induced accumulation of algal-available P (NaHCO3 and Fe oxide paper strip extractable P) in P-inactivating material which was even higher than those in raw sediment at initial stage (by 29.7% and 85.7%), although algal-available P substantially decreased in sediment after addition of the material and in the separated sediment from the mixtures. Given the possibility of exposing P-inactivating material to phytoplankton systems in overlying water typically during sediment resuspension, the accumulation suggested the potential of the resuspended material changing as P source for phytoplankton growth, increasing the uncertainties of sediment P immobilization method. Future work should focus more on the resuspension characteristics of P-inactivating material and on enhancing the capability of immobilizing algal-available P by the materials during internal P pollution control, especially in shallow lake.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143976"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PFAS (per- and polyfluorinated alkyl substances) as EDCs (endocrine-disrupting chemicals) - Identification of compounds with high potential to bind to selected terpenoids NHRs (nuclear hormone receptors).

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143967

Natalia Bulawska, Anita Sosnowska, Dominika Kowalska, Maciej Stępnik, Tomasz Puzyn

{"title":"PFAS (per- and polyfluorinated alkyl substances) as EDCs (endocrine-disrupting chemicals) - Identification of compounds with high potential to bind to selected terpenoids NHRs (nuclear hormone receptors).","authors":"Natalia Bulawska, Anita Sosnowska, Dominika Kowalska, Maciej Stępnik, Tomasz Puzyn","doi":"10.1016/j.chemosphere.2024.143967","DOIUrl":"10.1016/j.chemosphere.2024.143967","url":null,"abstract":"The objective of the subsequent study was to examine the probability of PFAS (per- and polyfluorinated alkyl substances) binding to various NHRs (nuclear hormone receptors) and to identify their structural features that contribute most to the binding score (BS). We evaluated the BS for PFAS in relation to 7 selected NHRs - 4 with additional antagonist forms (Retinoid X receptor alpha - RXRα, Liver X receptor alpha - LXRα, Liver X receptor beta - LXRβ, Estrogen receptor alpha - ERα, Estrogen receptor alpha antagonist - anti-ERα, Estrogen receptor beta - ERβ, Estrogen receptor beta antagonist - anti-ERβ, Glucocorticoid receptor - GR, Glucocorticoid receptor antagonist - anti-GR, Androgen receptor - AR, Androgen receptor antagonist - anti-AR). We based our study on the results of molecular docking, which we used to develop MLR-QSAR (Multiple Linear Regression - Quantitative Structure-Activity Relationship) models. The models we developed allowed us to predict the BS for an extensive set of PFAS compounds from the NORMAN database (more than 4000) - virtual screening. The probability of PFAS binding to selected receptors was determined by structural features such as particle size, branching, and fluorine content. These variables were also identified in the literature reports of experimental studies as the most important for this group of compounds. The research focused on receptors from the terpenoid group. The RXRα, LXRα and β, GR, and anti-GR receptors were shown to be the group less likely to be affected by PFAS. Sex hormones such as AR, anti-AR, ERα and ERβ with their antagonist forms are the most affected.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143967"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transformation behavior and toxicity assessment of beaytlmethodeyammonNium chbride (BAC-12) disinfectant during hospital wastewater treatment.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143981

Ruixue Guo, Jingjing Zhang, Jiaoqin Liu, Haifa E Alfassam, Hassan A Rudayni, Ahmed A Allam, Ruijuan Qu, Zongli Huo, Feng Zhu

{"title":"Transformation behavior and toxicity assessment of beaytlmethodeyammonNium chbride (BAC-12) disinfectant during hospital wastewater treatment.","authors":"Ruixue Guo, Jingjing Zhang, Jiaoqin Liu, Haifa E Alfassam, Hassan A Rudayni, Ahmed A Allam, Ruijuan Qu, Zongli Huo, Feng Zhu","doi":"10.1016/j.chemosphere.2024.143981","DOIUrl":"10.1016/j.chemosphere.2024.143981","url":null,"abstract":"This work focused on the transformation behavior of the emerging beaytlmethodeyammonium chbride (BAC-12) disinfectant existed in the treatment of medical sewage during its disinfection treatment. The degradation ability of ozone (O3) to BAC-12 was the best, followed by UV/NaOCl, UV, and NaOCl. The enhancement of BAC-12 in UV/NaOCl system is caused by the combined effect of UV photolysis, reactive chlorine species (RCS), and •OH. The transformation products of BAC-12 in the disinfection treatment were detected, and the chemical structure of products was rationalized by frontier molecular orbital and transition state theory methodologies. According to the ecological structure-activity relationship (ECOSAR) assessment, the intermediates of BAC-12 in UV, NaOCl, and UV/NaOCl treatments had lower half lethal concentration (LC50) and chronic toxicity (ChV) values with a higher ecotoxicity than BAC-12. O3 disinfection treatment of these toxic intermediates can significantly reduce the toxicity of the BAC-12 solution. This work provides necessary information on the potential environmental risks of BAC-12 arising from different disinfection methods in the treatment of medical wastewater.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143981"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green-synthesised silver and zinc oxide nanoparticles from stingless bee honey: Morphological characterisation, antimicrobial action, and cytotoxic assessment.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143961

Norfarina Bahari, Norhashila Hashim, Khalina Abdan, Abdah Mohd Akim, Bernard Maringgal, Laith Al-Shdifat

{"title":"Green-synthesised silver and zinc oxide nanoparticles from stingless bee honey: Morphological characterisation, antimicrobial action, and cytotoxic assessment.","authors":"Norfarina Bahari, Norhashila Hashim, Khalina Abdan, Abdah Mohd Akim, Bernard Maringgal, Laith Al-Shdifat","doi":"10.1016/j.chemosphere.2024.143961","DOIUrl":"10.1016/j.chemosphere.2024.143961","url":null,"abstract":"This study investigated the green synthesis of silver nanoparticles (Ag-NPs) and zinc oxide nanoparticles (ZnO-NPs) using an aqueous extract of stingless bee honey (SBH) as a reducing and stabilising agent. The rich compositions of SBH containing flavonoids, phenolics, organic acids, sugars, and enzymes makes the SBH extract an ideal biocompatible precursor for the NPs synthesis. Physicochemical characterisation of the synthesised NPs was performed using UV-Vis spectroscopy, FESEM, TEM, XRD, and FTIR spectroscopy. The results revealed that the Ag-NPs and ZnO-NPs exhibited polydispersity, with size ranges between 25-50 nm and 15-30 nm, respectively. A majority of the NPs possessed a spherical morphology. Furthermore, the study evaluated the antimicrobial activity of the SBH-based NPs against gram-positive (Staphylococcus aureus, ATCC 43300) and gram-negative (Escherichia coli, ATCC 25922) bacteria. The findings demonstrated significantly higher antimicrobial efficacy of the Ag-NPs with a zone of inhibition (ZOI) of 16.91 mm against S. aureus, and 17.43 mm against E. coli compared to the ZnO-NPs which having a ZOI of 13.05 mm and 14.01 mm, respectively. Notably, cytotoxicity assays revealed no adverse effects of the synthesised NPs on normal mouse fibroblast (3T3) and human lung fibroblast (MRC5) cells up to 100 μg/ml of concentration. These findings suggest the potential of SBH-based Ag-NPs and ZnO-NPs as safe and effective antibacterial agents for various applications, including pharmaceuticals, cosmetics, ointments, and lotions.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143961"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative grease interceptor to enhance fat, oil and grease removal from the wastewater generated from food service establishments.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143987

Nilufa Sultana, Felicity Roddick, Biplob Kumar Pramanik

{"title":"Innovative grease interceptor to enhance fat, oil and grease removal from the wastewater generated from food service establishments.","authors":"Nilufa Sultana, Felicity Roddick, Biplob Kumar Pramanik","doi":"10.1016/j.chemosphere.2024.143987","DOIUrl":"10.1016/j.chemosphere.2024.143987","url":null,"abstract":"Commercial grease interceptors (GIs), commonly used in food service establishments, are primarily designed to treat fat, oil and grease (FOG) from handwash sink (HS) wastewater. They are generally less effective for removing highly concentrated FOG from dishwasher (DW) effluents which contain highly emulsified FOG with complex long-chain fatty acids (LCFAs). Furthermore, standard testing of GIs uses diesel fuel to simulate FOG separation; however, the flow properties of typical cooking oils and animal fats differ significantly from diesel. We developed a novel GI (bench-scale with 72 L capacity) and examined the impact of various baffle configurations on FOG removal efficiency using samples containing representative FOG components of cooked oil, fat and food solids. The results demonstrated that the installation of two short baffles projecting from the top along with one short baffle projecting from the bottom in the first chamber, and another short baffle projecting from the top in the second chamber, led to FOG removal efficiencies of up to 88% and 40% for HS and DW effluents, respectively, at a hydraulic retention time (HRT) of 44 min. The short baffles acted as barriers, thus enhancing the loss of kinetic energy, subsequently ensuring a quiescent flow condition, resulting in an increased HRT for effective FOG separation. The addition of alum as coagulant at 200 mg/L (18.2 mg of Al3+/L) significantly enhanced the removal of FOG from treated DW effluents (up to 87%), effectively reducing the concentrations of various extra-LCFAs, such as paullinic (C20:1), arachidic (C20:0), eicosadienoic acid (C20:2), mead (C20:3), eicosapentaenoic (C20:5), erucic (C22:1), cervonic (C22:6), tricosanoic acid (C23:0), lignoceric (C24:0) and nervonic (C24:1) acid by up to 99%. These findings provide significant insights into the advanced GI design, offering a proactive solution to prevent fatberg formation while promoting a more sustainable and economically viable approach to sewer management.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143987"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elucidating the phytotoxic endpoints of sub-chronic exposure to titanium dioxide nanoparticles in Endemic Persian Dracocephalum species.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143853

Azam Chahardoli, Naser Karimi, Hamidreza Sharifan

{"title":"Elucidating the phytotoxic endpoints of sub-chronic exposure to titanium dioxide nanoparticles in Endemic Persian Dracocephalum species.","authors":"Azam Chahardoli, Naser Karimi, Hamidreza Sharifan","doi":"10.1016/j.chemosphere.2024.143853","DOIUrl":"10.1016/j.chemosphere.2024.143853","url":null,"abstract":"This study was designed to investigate the dichotomous effects of titanium dioxide nanoparticles (TiO2NPs) at varying concentrations (0, 50, 100, 1000, and 2500 ppm) on the physiological, biochemical, and antioxidative defense responses of Persian dragonhead plants cultivated in hydroponic conditions. Over 21 days of treatment, an increase in fresh shoot biomass by 26.2% and plant height by 18.2% was observed at exposure to 50 ppm TiO2NPs. Exposure to 100 ppm NPs negatively affected the biosynthesis of carotenoids, chlorophyll pigments (a, b, and total), and protein content. Field Emission Scanning Electron Microscopy (FE-SEM) and Transmission Electron Microscopy (TEM) analysis revealed TiO2NPs deposition within intercellular spaces and cell walls of root tissues. The physiological stress was prominent in response to 2500 ppm NPs as evidenced by a significant increase in proline and sugar content compared to the control. The enzymatic antioxidative defense was significantly upregulated by the enhanced activity of catalase (CAT) across exposure ranges 100-2500 ppm NPs, ascorbate peroxidase (APX) at 100 and 2500 ppm NPs, and peroxidase (POD) at 100 ppm NPs in plant roots. The antioxidant proficiency was further corroborated by increases in total flavonoids by 30.43% at 2500 ppm, saponins by 253.7%, and iridoids by 22.3% at 100 ppm NPs, relative to control. The results suggest that TiO2NPs fostered growth promotion at sub-lethal doses, and induced adverse biochemical changes at elevated concentrations, prompting the activation of intrinsic defense mechanisms to enhance plant resilience against NPs stresses. The optimal nano-stimulation performance was observed at 50 ppm TiO2NPs, which was suggested for the high yield targets, signifying a potential boon for agricultural productivity.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143853"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alternative assessment of machine learning to polynomial regression in response surface methodology for predicting decolorization efficiency in textile wastewater treatment.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143996

Jin-Kyu Kang, Youn-Jun Lee, Chae-Young Son, Seong-Jik Park, Chang-Gu Lee

{"title":"Alternative assessment of machine learning to polynomial regression in response surface methodology for predicting decolorization efficiency in textile wastewater treatment.","authors":"Jin-Kyu Kang, Youn-Jun Lee, Chae-Young Son, Seong-Jik Park, Chang-Gu Lee","doi":"10.1016/j.chemosphere.2024.143996","DOIUrl":"https://doi.org/10.1016/j.chemosphere.2024.143996","url":null,"abstract":"This study investigated the potential of machine learning (ML) as a substitute for polynomial regression in conventional response surface methodology (RSM) for decolorizing textile wastewater via a UV/H2O2 process. While polynomial regression offers limited adaptability, ML models provide superior flexibility in capturing nonlinear responses but are prone to overfitting, particularly with constrained RSM datasets. In this study, we evaluated decision tree (DT), random forest (RF), multilayer perceptron (MLP), and extreme gradient boosting (XGBoost) models with respect to a quadratic regression model. Our observations indicated that the ML models achieved higher R2 values, demonstrating better adaptability. However, when provided with additional data, the polynomial regression displayed a moderate predictability, whereas MLP and XGBoost exhibited indications of overfitting, while DT and RF remained robust. Both ANalysis Of VAriance (ANOVA) and SHapley Additive exPlanations (SHAP) analyses consistently emphasized the significance of operational factors (H2O2 concentration, reaction time, UV light intensity) in decolorization. The findings underscore the need for cautious validation when substituting ML models in RSM and highlight the complementary value of ML (particularly SHAP analysis) alongside conventional ANOVA for analyzing factor significance. This study offered significant insights into replacing polynomial regression with ML models in RSM.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":"370 ","pages":"143996"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sublethal effects of acidified water on sensorimotor responses and the transcriptome of zebrafish embryos.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143984

Jiun-Lin Horng, Kuan-Yi Lee, Li-Yih Lin

{"title":"Sublethal effects of acidified water on sensorimotor responses and the transcriptome of zebrafish embryos.","authors":"Jiun-Lin Horng, Kuan-Yi Lee, Li-Yih Lin","doi":"10.1016/j.chemosphere.2024.143984","DOIUrl":"https://doi.org/10.1016/j.chemosphere.2024.143984","url":null,"abstract":"Acidification of freshwater due to human activities is a widespread environmental problem. Its effects on the sensorimotor responses of fish, particularly during embryonic stages, may affect population fitness. To address this, zebrafish embryos were exposed to water at pH 7, 5 and 4.5 (adjusted with HCl) for 120 h. Acidic water did not increase mortality or cause obvious morphological abnormalities but reduced the size of the inner ear organs (otic vesicle and otolith) and the eye lens. It also suppressed ion uptake (Na+, Ca2+, K+) and induced embryonic acidosis. Behavioral tests at 4 or 5 days post fertilization revealed significant sensorimotor impairments: reduced touch-evoked escape responses (TEER), decreased acoustic startle responses (ASR) and decreased cadaverine avoidance responses (CAR). There were no effects on speed, acceleration and optomotor responses (OMR). Transcriptomic analyses identified 114 differentially expressed genes (DEGs) associated with ion transport, sensorimotor functions and other physiological processes. Overall, the jeopardizing effect of freshwater acidification threatens survival, highlighting the ecological risks and its potential impacts on fish populations.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143984"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term exposure to ambient air pollution and the incidence of systemic lupus erythematosus.

Chemosphere Pub Date : 2024-12-20 DOI: 10.1016/j.chemosphere.2024.143974

Lihong Ye, Ding Ye, Yu Qian, Jiayu Li, Bin Liu, Jiacheng Ying, Manli Wang, Hao Lin, Jing Guo, Xiaohui Sun, Zhixing He, Chengping Wen, Yingying Mao

{"title":"Long-term exposure to ambient air pollution and the incidence of systemic lupus erythematosus.","authors":"Lihong Ye, Ding Ye, Yu Qian, Jiayu Li, Bin Liu, Jiacheng Ying, Manli Wang, Hao Lin, Jing Guo, Xiaohui Sun, Zhixing He, Chengping Wen, Yingying Mao","doi":"10.1016/j.chemosphere.2024.143974","DOIUrl":"10.1016/j.chemosphere.2024.143974","url":null,"abstract":"The relationship between air pollution and the risk of systemic lupus erythematosus (SLE) remains inconclusive. Here, we investigated the associations between long-term exposure to ambient air pollutants and incident SLE, based on a cohort of 502,004 participants free of SLE at baseline from UK Biobank. During a median of 13.65 follow-up years, 638 patients with SLE were identified. For each increase of interquartile range in air pollutant concentrations, the hazard ratios (HRs) and 95% confidence intervals (CIs) of SLE were 1.15 (1.04-1.27) for nitrogen dioxide (NO2), 1.08 (1.00-1.17) for nitrogen oxides (NOx), 1.13 (1.03-1.24) for particulate matter with the diameters ≤2.5 μm (PM2.5), 1.06 (0.99-1.14) for particulate matter with diameter between 2.5 μm and 10 μm (PMcoarse), and 1.10 (1.02-1.18) for particulate matter with diameter ≤10 μm (PM10), respectively. A non-linear relationship of PMcoarse with SLE risk was detected by using restricted cubic spline models (Pnon-linearity = 0.009), but not for the remaining air pollutants. Furthermore, smoking and long-term exposure to PM pollutants had significant additive interaction on SLE risk, with a relative excess risk of additive interaction (RERI) of 0.07 (95% CI: 0.02-0.09) for PM2.5, and 0.05 (95% CI: 0.01-0.08) for PM10. Additive interactions were also observed for genetic risk and PMcoarse (RERI: 0.04, 95% CI: 0.00-0.07) and PM10 (RERI: 0.04, 95% CI: 0.02-0.06) on SLE risk. In conclusion, our findings emphasize the significance of evaluating the impacts of long-term exposure to ambient air pollutants in preventing SLE, and highlight the necessity to identify individuals who smoke and have a high genetic risk to minimize the harmful effects of air pollution on the development of SLE.","PeriodicalId":93933,"journal":{"name":"Chemosphere","volume":" ","pages":"143974"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0