Biological research for nursing最新文献_第7页

Aerobic Training and Ointment Effect on range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model. 有氧训练和药膏对关节挛缩症患者活动范围、von Willebrand因子、血管内皮因子和股动脉血流动力学的影响：大鼠模型。

Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-08-14 DOI: 10.1177/10998004241274290

Palida Maimaiti, Jiaojiao Shu, Tianyu Miao, Nuerbiya Keqike, Asiguli Tuersun, Ruiqi Yang, Ningning Wang

{"title":"Aerobic Training and Ointment Effect on range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model.","authors":"Palida Maimaiti, Jiaojiao Shu, Tianyu Miao, Nuerbiya Keqike, Asiguli Tuersun, Ruiqi Yang, Ningning Wang","doi":"10.1177/10998004241274290","DOIUrl":"10.1177/10998004241274290","url":null,"abstract":"Objective: Using a rat model, we investigated the effect of multidisciplinary rehabilitation, including aerobic training and ointment, on the ROM, vWF, VEGF content, and femoral artery hemodynamics in rats with joint contracture.Methods: A total of 44 Wistar rats were divided into the normal control group (NC, eight rats) and the experimental group (EG). A joint contracture model was established for the rats in the EG group by an external fixator. After fixator removal, 32 rats are further divided into the MC, SC, RE, and SR groups (n = 8). Before and after the 42 day intervention, the ROM, vWF, VEGF, PS, ED, and RI were measured using X-ray imaging, ELISA, and color Doppler ultrasound, respectively.Results: After fixator removal, ROM for EG group was lower than that of the NC group (p < .01). After the intervention, ROM for the SR, RE, and SC groups was improved. The ROM for the SR group reached a similar value for NC group. vWF and VEGF levels in SR group were lower than in the MC, SC, and RE groups (p < .05), and had a similar value to the NC groups. PS value for SR and RE groups was higher than the MC and SC groups. The RI value for SR group was higher than that of NC and MC groups.Conclusion: Multidisciplinary rehabilitation used in this study can treat joint contracture synergistically. It improves the ROM of the joint, reduces the content of vWF and VEGF, and improves the femoral artery hemodynamics.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"17-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IL-16 Mediates the Effect of Circulating Metabolites on Postmenopausal Osteoporosis: A Two-Step, Multivariable Mendelian Randomization Study. IL-16 介导循环代谢物对绝经后骨质疏松症的影响：一项两步多变量孟德尔随机研究

Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-08-30 DOI: 10.1177/10998004241279934

Yi Chen, Hefang Xiao, Fei Teng, Ao Yang, Fei Yang, Changshun Chen, Rongjin Chen, Bin Geng, Yayi Xia

{"title":"IL-16 Mediates the Effect of Circulating Metabolites on Postmenopausal Osteoporosis: A Two-Step, Multivariable Mendelian Randomization Study.","authors":"Yi Chen, Hefang Xiao, Fei Teng, Ao Yang, Fei Yang, Changshun Chen, Rongjin Chen, Bin Geng, Yayi Xia","doi":"10.1177/10998004241279934","DOIUrl":"10.1177/10998004241279934","url":null,"abstract":"Objectives: This study aimed to explore the relationship between circulating metabolites and postmenopausal osteoporosis (PMOP) and to assess the mediating role of inflammatory factors. Methods: Utilizing summary-level data from genome-wide association studies (GWAS) and employing a Mendelian Randomization approach, a two-sample MR analysis was conducted to assess the relationship between circulating metabolites and PMOP. Additionally, a two-step MR was used to quantify the mediating impact of inflammatory factors on the effect of circulating metabolites on PMOP. Results: The results revealed a significant association between certain metabolites and the risk of PMOP, notably the ratio of free cholesterol to total lipids in very large VLDL particles (OR: 1.399, 95% CI: 1.002-1.954, p = 0.048) and IL-16 (OR: 0.773, 95% CI: 0.608-0.983, p = 0.036). IL-16 was found to partially mediate the impact of circulating metabolites on PMOP, with a mediation effect of 10.4%. Conclusion: This study underscores the crucial role of circulating metabolites and inflammatory factors in PMOP pathogenesis. A causal relationship between circulating metabolites and PMOP was established, with IL-16 mediating some effects. These findings hold promise for clinical applications in early detection, personalized medicine, and the identification of therapeutic targets for PMOP.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mind-Body Intervention for Diabetic Neuropathy: A Pilot Study on Yoga's Effects on Muscle Strength, Proprioception, Fear of Falling, Pain, and Quality of Life. 糖尿病神经病变的身心干预：瑜伽对肌肉力量、直觉、跌倒恐惧、疼痛和生活质量影响的试点研究。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-05-29 DOI: 10.1177/10998004241256097

Mohammad Ali Faridi Dastjerdi, Gholamali Ghasemi, Hamed Esmaeili, Negin Ghasemi Kahrizsangi

{"title":"Mind-Body Intervention for Diabetic Neuropathy: A Pilot Study on Yoga's Effects on Muscle Strength, Proprioception, Fear of Falling, Pain, and Quality of Life.","authors":"Mohammad Ali Faridi Dastjerdi, Gholamali Ghasemi, Hamed Esmaeili, Negin Ghasemi Kahrizsangi","doi":"10.1177/10998004241256097","DOIUrl":"10.1177/10998004241256097","url":null,"abstract":"Objective: The aim of this study was to investigate the effects of an 8-week yoga intervention on muscle strength, proprioception, pain, concerns about falling, and quality of life in individuals diagnosed with diabetic neuropathy.Methods: A quasi-experimental design incorporating a pretest-posttest methodology and a control group was implemented in the present study. A total of 30 patients who were diagnosed with type 2 diabetes and neuropathy were recruited and randomly assigned to intervention (n = 15) or non-exercise control (n = 15). Yoga sessions were conducted for a duration of 60 min on three occasions per week, with participants requested to practice at home on other days.Results: The results showed significant main effects of time on the muscle strength (both flexor and extensor muscles, p < .001, ηp2 = 0.652 and p < .001, ηp2 = 0.539, respectively), proprioception error (p < .001, ηp2 = 0.807), pain intensity (p < .001, ηp2 = 0.538), concerns about falling (p < .001, ηp2 = 0.700), and overall score of quality of life (p < .001, ηp2 = 0.475). Moreover, there were significant group-by-time interactions for all variables (p < .001 for all).Conclusion: The study reveals that yoga intervention can be an effective alternative therapeutic approach to medication for individuals with diabetic neuropathy. Yet, future studies are needed on a larger sample size to strengthen the present understanding of the advantageous impact of yoga intervention in this population.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"537-546"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141177102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative Oral Carbohydrates for Children: A Meta-Analysis and Systematic Review. 儿童术前口服碳水化合物：元分析和系统回顾

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-11 DOI: 10.1177/10998004241253536

Yan Li, Luxi Chen, Yang Su, Xin Zhang

{"title":"Preoperative Oral Carbohydrates for Children: A Meta-Analysis and Systematic Review.","authors":"Yan Li, Luxi Chen, Yang Su, Xin Zhang","doi":"10.1177/10998004241253536","DOIUrl":"10.1177/10998004241253536","url":null,"abstract":"Background: Many studies have reported the use of preoperative oral carbohydrates (CHO) in children, but the results are inconsistent. The aim of this meta-analysis is to assess the effectiveness and safety of oral CHO administration in children prior to surgery, with the goal of offering a dependable reference for clinical nursing practices and surgical interventions. Methods: Two authors searched PubMed, Clinical trials, Web of Science, Embase, Cochrane Library, China national knowledge infrastructure (CNKI), Wanfang and Weipu databases for randomized controlled trial (RCT) on the effects of preoperative oral CHO in children up to April 12, 2024. We used RevMan 5.4 software for data analysis. Results: Nine RCTs involving a total of 1279 children were included. The meta-analysis showed that there was statistical difference in the pH of gastric juice (MD = 1.54, 95%CI: 1.40-1.67, p < .001), intraoperative sedation score (MD = 0.62, 95%CI: 0.27-0.97, p < .001), and the incidence of postoperative nausea and vomiting (OR = 0.40, 95%CI: 0.20-0.80, p = .009) between the CHO and control groups. There was no statistical difference in the RGV (MD = -0.23, 95%CI: -0.47-0.01, p = .06) and the postoperative blood glucose level (MD = -0.91, 95%CI: -5.03-3.21, p = .67) between the CHO and control groups. Egger regression analysis showed that there were no publication biases amongst the synthesized outcomes (all p > .05). Conclusion: The administration of oral CHO to children before surgery is safe and practicable. There is a need for additional, well-conducted studies with more participants to further elucidate the role of preoperative CHO administration.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"624-635"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Not All Frailty Assessments Are Created Equal: Comparability of Electronic Health Data-Based Frailty Assessments in Assessing Older People in Residential Care. 并非所有的虚弱评估都一样：基于电子健康数据的虚弱评估在评估养老院老人时的可比性。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-05-13 DOI: 10.1177/10998004241254459

Jonathan Kong, Kelly Trinh, Kathrine Hammill, Carla Chia-Ming Chen

{"title":"Not All Frailty Assessments Are Created Equal: Comparability of Electronic Health Data-Based Frailty Assessments in Assessing Older People in Residential Care.","authors":"Jonathan Kong, Kelly Trinh, Kathrine Hammill, Carla Chia-Ming Chen","doi":"10.1177/10998004241254459","DOIUrl":"10.1177/10998004241254459","url":null,"abstract":"Objectives: To evaluate the comparability of frailty assessment tools - the electronic frailty index (eFI), retrospective electronic frailty index (reFI), and clinical frailty scale (CFS) - in older residents of care facilities. Methods: Data from 813 individuals aged 65 or older, with frailty and co-morbidities, collected between 2022 and 2023, were analysed using various statistical methods. Results: The results showed significant differences in frailty classification among the tools: 78.3% were identified as moderately to severely frail by eFI, 59.6% by reFI, and 92.1% by CFS. Statistical tests confirmed significant differences (p < .05) in their assessments, indicating variability in measurement methods. Discussion: This study advances the understanding of frailty assessment within aged-care settings, highlighting the differences in the efficacy of these assessment tools. It underscores the challenges in frailty assessments and emphasizes the need for continuous refinement of assessment methods to address the diverse facets of frailty in aged care.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"526-536"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonpharmacological Interventions for Managing Symptom Clusters in Adults: A Systematic Review. 用于控制成人症状群的非药物干预措施：系统回顾。

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-20 DOI: 10.1177/10998004241261258

Taekyeong Lee, Jongmin Park

{"title":"Nonpharmacological Interventions for Managing Symptom Clusters in Adults: A Systematic Review.","authors":"Taekyeong Lee, Jongmin Park","doi":"10.1177/10998004241261258","DOIUrl":"10.1177/10998004241261258","url":null,"abstract":"Objectives: The complex effects of multiple co-occurring symptoms are a major cause of reduced quality of life; thus, it is necessary to identify symptom clusters experienced by patients and explore interventions. This study aimed to provide an overview of non-pharmacological interventions based on symptom clusters in adults to identify effective intervention strategies and methods. Methods. This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. For the search databases, PubMed, Embase, Cochrane Library, CINAHL, RISS, KISS, and KISTI were used. It includes English and Korean experimental studies published up to May 2023. The literature quality was evaluated using the Joanna Briggs Institute Quality Assessment Tool. Results. Of the 18 studies selected, 15 were randomized controlled trials and three were quasi-experimental studies, all of which were conducted on patients with cancer. The symptom clusters-based interventions in the literature are classified as movement-based, relaxation-based, integrated, and miscellaneous interventions. Integrated interventions, which were effective in all studies, might prove to be very effective for managing symptom clusters. Movement-based intervention studies, which include dance, Qigong, and Tai Chi, might be very effective in improving health-related quality of life (HRQoL). Conclusions. This review demonstrates that non-pharmacological interventions reduce the occurrence and severity of symptom clusters, thereby improving HRQoL. Further studies are required to evaluate the effects of these interventions in patients with various chronic conditions other than cancer.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"657-674"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DNA Methylation, Inflammation, and Neurobehavior in Preterm Infants. 早产儿的 DNA 甲基化、炎症和神经行为

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-05 DOI: 10.1177/10998004241257664

Marliese Dion Nist, Rita H Pickler, Abigail B Shoben, Yvette P Conley

{"title":"DNA Methylation, Inflammation, and Neurobehavior in Preterm Infants.","authors":"Marliese Dion Nist, Rita H Pickler, Abigail B Shoben, Yvette P Conley","doi":"10.1177/10998004241257664","DOIUrl":"10.1177/10998004241257664","url":null,"abstract":"Objectives: Inflammation contributes to disparate neurodevelopmental outcomes between preterm and term-born infants. In this context, DNA methylation may contribute to inflammation by affecting gene expression. Brain-derived neurotrophic factor (BDNF) and nuclear factor-kappa-B-inhibitor alpha (NFKBIA) are important genes for targeted DNA methylation analysis. The aims of this study were to (1) identify associations between inflammatory factors and BDNF and NFKBIA methylation, and (2) identify associations between BDNF and NFKBIA methylation and early neurobehavior in preterm infants. Methods: In a longitudinal cohort study of preterm infants born 28-31 weeks gestational age, blood samples were collected weekly for the quantification of inflammatory factors. We extracted DNA from saliva samples and quantified methylation of six BDNF cytosine-phosphate-guanine (CpG) sites and five NFKBIA CpG sites. Neurobehavior was assessed using the Neurobehavioral Assessment of the Preterm Infant. Results: Sixty-five infants were included in the analysis. In females, inflammatory factors were positively associated with BDNF methylation of most CpG sites. Interleukin-1 receptor antagonist was negatively associated with NFKBIA methylation at two CpG sites. In males, interleukin-6 was negatively associated with BDNF and NFKBIA methylation at most CpG sites. In females, BDNF methylation at two sites was inversely associated with motor performance. In males, NFKBIA methylation at one site was inversely associated with motor performance. Conclusion: This study provides evidence for the relationship between inflammation and neurobehavior in preterm infants, working mechanistically through DNA methylation. The finding of a difference between males and females suggests that female infants are potentially more vulnerable to inflammation and warrants future study.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"547-558"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MicroRNA Profiles in Hematopoietic Stem Cell Transplant Recipients. 造血干细胞移植受者的微 RNA 图谱

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-05-31 DOI: 10.1177/10998004241257847

Lathika Mohanraj, Christiane Carter, Jinze Liu, Theresa Swift-Scanlan

{"title":"MicroRNA Profiles in Hematopoietic Stem Cell Transplant Recipients.","authors":"Lathika Mohanraj, Christiane Carter, Jinze Liu, Theresa Swift-Scanlan","doi":"10.1177/10998004241257847","DOIUrl":"10.1177/10998004241257847","url":null,"abstract":"Background: Hematopoietic Stem Cell Transplant (HCT) is a potentially curative treatment for hematologic malignancies, including multiple myeloma. Biomarker investigation can guide identification of HCT recipients at-risk for poor outcomes. MicroRNAs (miRNAs) are a class of non-coding RNAs involved in the modulation and regulation of pathological processes and are emerging as prognostic and predictive biomarkers for multiple health conditions. This pilot study aimed to examine miRNA profiles associated with HCT-related risk factors and outcomes in patients undergoing autologous HCT. Methods: Patients eligible for autologous HCT were recruited and blood samples and HCT-related variables were collected. Differential expression analysis of miRNA was conducted on 24 patient samples to compare changes in miRNA profile in HCT eligible patients before and after transplant. Results: Unsupervised clustering of differentially expressed (p < .05) miRNAs pre- and post- HCT identified clusters of up- and down-regulated miRNAs. Four miRNAs (miR-125a-5p, miR-99b-5p, miR-382-5p, miR-145-5p) involved in hematopoiesis (differentiation of progenitor cells, granulocyte function, thrombopoiesis, and tumor suppression) were significantly downregulated post-HCT. Correlation analyses identified select miRNAs associated with risk factors (such as frailty, fatigue, cognitive decline) and quality of life pre- and post-HCT. Select miRNAs were correlated with platelet engraftment. Conclusion: Future studies should examine miRNA signatures in larger cohorts in association with HCT outcomes; and expand investigations in patients receiving allogeneic transplants. This will lead to identification of biomarkers for risk stratification of HCT recipients.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"559-568"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Systemic Immune Inflammation Indexes and DVT in Patients With Malignancy Requiring PICC Insertion. 需要插入 PICC 的恶性肿瘤患者全身免疫炎症指数与深静脉血栓之间的关系

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-05-07 DOI: 10.1177/10998004241252468

Na Li, Jing Huang, You Feng, Hucheng Yan, Shihui Min, Xin Chen

{"title":"Association Between Systemic Immune Inflammation Indexes and DVT in Patients With Malignancy Requiring PICC Insertion.","authors":"Na Li, Jing Huang, You Feng, Hucheng Yan, Shihui Min, Xin Chen","doi":"10.1177/10998004241252468","DOIUrl":"10.1177/10998004241252468","url":null,"abstract":"Background: In order to reduce the risk of leakage of cytotoxic agents, peripherally inserted central catheters (PICC) are widely used in patients diagnosed with malignancy before chemotherapy. While inflammation has been demonstrated to be associated with deep vein thrombosis (DVT), the connection between systemic immune inflammation indexes and the formation of PICC-DVT remains unclear. Purpose: This study aims to evaluate the association between PICC-DVT and systemic immune inflammation indexes including platelet-to-lymphocyte ratio (PLR), systemic immune-inflammatory index (SII), and systemic inflammatory response index (SIRI). Methods: From August 2018 to October 2021, we enrolled consecutive patients diagnosed with malignancy who underwent PICC implantation before chemotherapy. DVT was assessed using color Doppler ultrasonography. Results: Among the 513 patients, 57 patients (11.1%) developed PICC-DVT. The optimal cutoff values for PLR, SII and SIRI were 260.1, 1318.7, and 2.7, respectively. Based on the multiple logistic regression analysis, correlations were found between PICC-DVT and elevated PLR (p = .014), SII (p = .012), and SIRI (p = .022). Patients with malignancy having higher values of PLR, SII or SIRI tended to be more likely to develop PICC-DVT. Conclusions: The systemic immune inflammation indexes increases the risk of PICC-DVT and could be used as auxiliary predictive tests for PICC-DVT.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"518-525"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal Gut Microbiota Predicts Temperament in Offspring at 1-2 Years. 产前肠道微生物群可预测1-2岁后代的性情

Biological research for nursing Pub Date : 2024-10-01 Epub Date: 2024-06-12 DOI: 10.1177/10998004241260894

Yanan Cao, Xu Zhang, Qianping Zhang, Xiaoxiao Fan, Tianzi Zang, Jinbing Bai, Yuanyuan Wu, Wenjie Zhou, Yanqun Liu

{"title":"Prenatal Gut Microbiota Predicts Temperament in Offspring at 1-2 Years.","authors":"Yanan Cao, Xu Zhang, Qianping Zhang, Xiaoxiao Fan, Tianzi Zang, Jinbing Bai, Yuanyuan Wu, Wenjie Zhou, Yanqun Liu","doi":"10.1177/10998004241260894","DOIUrl":"10.1177/10998004241260894","url":null,"abstract":"The purpose of this study was to explore whether prenatal gut microbiota (GM) and its functions predict the development of offspring temperament. A total of 53 mothers with a 1-year-old child and 41 mothers with a 2-year-old child were included in this study using a mother-infant cohort from central China. Maternal fecal samples collected during the third trimester were analyzed using 16S rRNA V3-V4 gene sequences. Temperament of the child was measured by self-reported data according to the primary caregiver. The effects of GM in mothers on offspring's temperament were evaluated using multiple linear regression models. The results demonstrated that the alpha diversity index Simpson of prenatal GM was positively associated with the activity level of offspring at 1 year (adj. P = .036). Bifidobacterium was positively associated with high-intensity pleasure characteristics of offspring at 1 year (adj. P = .031). Comparatively, the presence of Bifidobacterium found in the prenatal microbiome was associated with low-intensity pleasure characteristics in offspring at 2 years (adj. P = .031). There were many significant associations noted among the functional pathways of prenatal GM and temperament of offspring at 2 years. Our findings support the maternal-fetal GM axis in the setting of fetal-placental development with subsequent postnatal neurocognitive developmental outcomes, and suggest that early childhood temperament is in part associated with specific GM in the prenatal setting.","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"569-583"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0