Arquivos brasileiros de cardiologia最新文献_第6页

Vasoplegic Syndrome under Extracorporeal Membrane Oxygenation: Successful Treatment with Methylene Blue. 体外膜氧合下血管截瘫综合征：亚甲基蓝成功治疗。

Arquivos brasileiros de cardiologia Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20250070

Ahmet Aydin, Banu Katlan, Selman Kesici

引用次数: 0

Septal Artery Embolization with Onyx® In Hypertrophic Cardiomyopathy: Report of Two Cases. Onyx®治疗肥厚性心肌病中隔动脉栓塞2例报告

Arquivos brasileiros de cardiologia Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20240656

Anna Luiza Souza, Patrícia Ferreira Demuner, Giulliano Gardenghi, Débora Rodrigues, Fernando Henrique Fernandes, Sidney Munhoz Júnior, Maurício Lopes Prudente

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Beyond Limits: What 366 Consecutive Marathons Reveal about the Human Heart. 超越极限：366个连续的马拉松揭示了人类的心脏。

Arquivos brasileiros de cardiologia Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20250231

Fabricio Braga, Ricardo Stein

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Echoes of the Past: The Intriguing Link between Chagas Disease and Insulin. 过去的回声：恰加斯病和胰岛素之间的有趣联系。

Arquivos brasileiros de cardiologia Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20250295

Marcia M Noya-Rabelo, Olga Souza

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Why Cardiology Can No Longer Ignore Sexual Health? 为什么心脏病学不能再忽视性健康？

Arquivos brasileiros de cardiologia Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20250326

Ricardo Stein, Filipe Ferrari

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Hospitalizations and In-Hospital Mortality from Heart Failure in Brazil: An Updated Overview. 巴西心力衰竭住院率和住院死亡率：最新综述

Arquivos brasileiros de cardiologia Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI: 10.36660/abc.20250284

Adriana Lopes Latado

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Association between Glucose/lymphocytes Ratio and Contrast-Induced Acute Kidney Injury in Patients with Myocardial Infarction without Diabetes Mellitus. 葡萄糖/淋巴细胞比值与非糖尿病心肌梗死患者造影剂诱导急性肾损伤的关系

IF 1.9

Arquivos brasileiros de cardiologia Pub Date : 2025-07-01 DOI: 10.36660/abc.20240869

Murat Gök, Alparslan Kurtul, Orçun Demir, Kenan Yalta

{"title":"Association between Glucose/lymphocytes Ratio and Contrast-Induced Acute Kidney Injury in Patients with Myocardial Infarction without Diabetes Mellitus.","authors":"Murat Gök, Alparslan Kurtul, Orçun Demir, Kenan Yalta","doi":"10.36660/abc.20240869","DOIUrl":"https://doi.org/10.36660/abc.20240869","url":null,"abstract":"Background: Glucose metabolism and systemic inflammation appears to be strongly related to many cardiovascular diseases. Glucose to lymphocyte ratio (GLR), a novel promising marker, has been recognized as a reliable predictor of prognosis in various cancers. However, there are still no studies on the association of cardiovascular disease with GLR.Objectives: This analysis aimed to uncover the potential association between GLR and the risk for contrast-induced acute kidney injury (CI-AKI) after primary percutaneous coronary intervention (PPCI) in a ST-elevation acute myocardial infarction (STEMI) population.Methods: Clinical data of 592 nondiabetic STEMI patients managed with PPCI from February 2021 to February 2023 were retrospectively analyzed. Patients with end-stage kidney disease, missing laboratory data, cancers, inflammatory/infectious diseases, or died during the procedure or within 24 hours after the procedure were excluded. The receiver operating characteristic curve was used to determine the optimal cutoff of GLR in CI-AKI. Based on the cutoff value, the study population was categorized into high-GLR (≥4.16) and low-GLR (<4.16) groups. The level of significance adopted in the statistical analysis was 5%.Results: The overall CI-AKI incidence was 7.4%. The high-GLR group showed a higher CI-AKI incidence in comparison to the low-GLR group (30.9%vs1.3%, p<0.001). Following adjustment for potential confounders, high-GLR still served as an independent predictor for CI-AKI (odds ratio [OR] 45.100, 95% confidence interval [CI] 7.312-278.174, p<0.001), as well as creatinine at admission (OR:10.459, 95%CI 1.169-93.583, p=0.036).Conclusions: In conclusion, a high GLR level served as an independent risk factor for CI-AKI evolution after PPCI in subjects with STEMI without diabetes mellitus.","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 8","pages":"e20240869"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Reversals, Spins and Divergent Results in Cardiology Trials. 心脏病学试验中的医学逆转、旋转和不同结果

IF 1.9

Arquivos brasileiros de cardiologia Pub Date : 2025-07-01 DOI: 10.36660/abc.20240884

José Nunes de Alencar, Bruno Robalinho Cavalcanti, Guilherme Augusto Teodoro Athayde

{"title":"Medical Reversals, Spins and Divergent Results in Cardiology Trials.","authors":"José Nunes de Alencar, Bruno Robalinho Cavalcanti, Guilherme Augusto Teodoro Athayde","doi":"10.36660/abc.20240884","DOIUrl":"https://doi.org/10.36660/abc.20240884","url":null,"abstract":"Cardiovascular medicine has witnessed remarkable breakthroughs, yet even highly regarded interventions can be undermined by flawed reasoning, excessive mechanistic assumptions, and the selective reporting of data. This article examines crucial pitfalls in contemporary cardiology, such as medical reversals, the impact of spin, and how bayesian methods can offer greater clarity in evaluating evidence, as they integrate prior knowledge with new data to generate more probabilistic, context-driven conclusions. This review advocates for a measured, critical approach to research appraisal, cautioning cardiologists against uncritically accepting trial conclusions at face value. Adopting this vigilant stance will help ensure that emerging therapies and interventions genuinely advance patient outcomes, guiding physicians toward more credible, transparent, and beneficial strategies in the ever-evolving field of cardiovascular medicine. Such vigilance is important to preserve the integrity of scientific inquiry and meaningful progress in patient care. This approach promotes reliability of published data.","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 7","pages":"e20240884"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening for Lysosomal Acid Lipase Deficiency in a Lipid Clinic. 筛选溶酶体酸性脂肪酶缺乏症在血脂诊所。

IF 1.9

Arquivos brasileiros de cardiologia Pub Date : 2025-07-01 DOI: 10.36660/abc.20240825

Zenia Brasil, Francisco Antonio H Fonseca, Marco Antonio Curiati, Sandra Obikawa Kyosen, Vanessa Gonçalves Pereira, Waleria Toledo Fonzar, João Bosco Pesquero, Francy Reis da Silva Patrício, Marcelo Hideki Yamamoto, Joyce Umbelino Yamamoto, Vania D'Almeida, Ana Maria Martins, Maria Cristina Izar

{"title":"Screening for Lysosomal Acid Lipase Deficiency in a Lipid Clinic.","authors":"Zenia Brasil, Francisco Antonio H Fonseca, Marco Antonio Curiati, Sandra Obikawa Kyosen, Vanessa Gonçalves Pereira, Waleria Toledo Fonzar, João Bosco Pesquero, Francy Reis da Silva Patrício, Marcelo Hideki Yamamoto, Joyce Umbelino Yamamoto, Vania D'Almeida, Ana Maria Martins, Maria Cristina Izar","doi":"10.36660/abc.20240825","DOIUrl":"https://doi.org/10.36660/abc.20240825","url":null,"abstract":"Background: Lysosomal acid lipase deficiency (LAL-D) is a rare autosomal recessive disease, with massive accumulation of cholesteryl esters and triglycerides in many organs, leading to hepatosplenomegaly, microvesicular steatosis, cirrhosis and premature death. Early recognition is crucial for timely enzyme replacement therapy.Objectives: To screen for LAL-D in subjects with dyslipidemias and/or liver disease at an outpatient lipid clinic.Methods: We retrospectively assessed records from 2,018 adults and children using a screening algorithm including ALT/AST elevation >1.5 x upper limit of normality, LDL-C>160 mg/dL, HDL-C<40 (males) or <50 mg/dL (females) in adults, and LDL-C>130 mg/dL, HDL-C<45 mg/dL, in children. High-risk patients for LAL-D were selected for LAL enzymatic activity assay in dried blood spots using LAL inhibitor, Lalistat-2.Results: Among 2,018 screened patients, 21 (0.92%) were selected for LAL activity test, but only eight performed the test with normal results [mean LAL activity 0.077 ± 0.03 nmol/punch/h (reference value >0.024 nmol/punch/h)]. A child whose mother did not perform the test, had a post-mortem undetectable LAL activity. Further, the mother and three half-brothers confirmed LAL-D. Sequencing (NGS) of LIPA gene did not find pathogenic variants, not allowing to discard changes in non-coding region of the gene analyzed.Conclusions: Identifying LAL-D remains a challenge, and an algorithm based on clinical and laboratory criteria may assist in selecting patients for LAL-D screening. Given its rarity and overlapping features with other genetic dyslipidemias, LAL-D is primarily a diagnosis of exclusion, often considered when other conditions have been ruled out.","PeriodicalId":93887,"journal":{"name":"Arquivos brasileiros de cardiologia","volume":"122 7","pages":"e20250825"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial Intelligence Assistance in the Peer Review Analysis of Medical Articles: Advantages, Disadvantages, and Ethical Considerations. 人工智能辅助医学文章的同行评议分析：优点、缺点和伦理考虑。

IF 1.9

Arquivos brasileiros de cardiologia Pub Date : 2025-07-01 DOI: 10.36660/abc.20250315

André Zimerman, Andre d'Avila

引用次数: 0