Annales de biologie clinique最新文献_第2页

[9th International "Alain Feuillu" Symposium - Emergency biology and blood gases].

Annales de biologie clinique Pub Date : 2024-10-01 DOI: 10.1684/abc.2024.1919

Christian Aussel, Marie-Christine Beauvieux, Stéphane Bermon, Hervé Bisiau, Stéphane Debroczi, Pierre Dupuis, Christoph Ganter, Jérémy Guénezan, Jacques Izopet, Marianne Lafitte, Agnès Mailloux, Sophie Pasini, Pascal Pernet, Xavier Poble, Michel Vaubourdolle

引用次数: 0

[World lab 2024: a new page in Dubai].

Annales de biologie clinique Pub Date : 2024-10-01 DOI: 10.1684/abc.2024.1918

Katell Peoc'h, Marie Lenski

引用次数: 0

[Rare genetic diseases in the MENA Region (Middle East and North Africa): Challenges, regional specificities, and future perspectives].

Annales de biologie clinique Pub Date : 2024-10-01 DOI: 10.1684/abc.2024.1916

Merieme Bensalah

引用次数: 0

[Implementation of edoxaban anti-Xa activity assay in a hospital laboratory and evaluation of its analytical performance]. [埃多沙班抗 Xa 活性测定在医院实验室的应用及其分析性能评估]。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1910

Corentin S Lefebvre, Sophie Luneau, Nûn Kalim Bentounes, Laetitia Mauge, Aurélie Dumont, Pascale Gaussem, Dominique Helley, David M Smadja, Nicolas Gendron

{"title":"[Implementation of edoxaban anti-Xa activity assay in a hospital laboratory and evaluation of its analytical performance].","authors":"Corentin S Lefebvre, Sophie Luneau, Nûn Kalim Bentounes, Laetitia Mauge, Aurélie Dumont, Pascale Gaussem, Dominique Helley, David M Smadja, Nicolas Gendron","doi":"10.1684/abc.2024.1910","DOIUrl":"10.1684/abc.2024.1910","url":null,"abstract":"Edoxaban is a direct oral anticoagulant available in Europe but not in France. Given the high tourist traffic in France, understanding the pharmacology of edoxaban and the availability of its laboratory testing seemed crucial in emergency situations. The aim of this work was to describe the methodology for measuring the anti-Xa activity of edoxaban, highlighting pre-analytical and analytical aspects, along with essential clinico-biological data for therapeutic guidance. The analysis was performed using the chromogenic method on the STAR-Max analyzer, with the STA®-Liquid ANTI-Xa kit (Diagnostica Stago®). Anti-Xa Edoxaban level measurement has a detection limit of 15 ng/mL, a quantification limit of 20 ng/mL and a linearity limit of 400 ng/mL. Repeatability, intermediate precision, accuracy, and measurement uncertainty studies were conducted to assess method performance, meeting quality requirements. The comparison between two STAR-Max® analyzers showed excellent results with linear regression and a low bias with good precision and no loss of dispersion regardless of edoxaban levels. In conclusion, although the measurement of edoxaban level may be rarely necessary in clinical practice, its implementation is straightforward. The availability of edoxaban in neighboring countries, underscores the importance of having its measurement available in hospital laboratories.","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 4","pages":"451-460"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142142018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Method comparison between two hemostasis analyzers: STA R Max³ and Cobas t 511]. [两种止血分析仪的方法比较：STA R Max3 和 Cobas t 511]。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1904

Sophie Melicine, Nazanine Bayani, Juliette Vo Xuan, Maeva Deleray, Rym Chouk, Rita Creidy, Bassem Khazem

{"title":"[Method comparison between two hemostasis analyzers: STA R Max3 and Cobas t 511].","authors":"Sophie Melicine, Nazanine Bayani, Juliette Vo Xuan, Maeva Deleray, Rym Chouk, Rita Creidy, Bassem Khazem","doi":"10.1684/abc.2024.1904","DOIUrl":"10.1684/abc.2024.1904","url":null,"abstract":"The STA R Max3 (Stago, France) and Cobas t511 (Roche Diagnostics, Germany) are two automated hemostasis analysers that can be used to perform a wide range of tests. The STA R Max3 uses a mechanical clot detection system to measure coagulation times, while the Cobas t511 uses optical detection. The aim of this study was to compare the analytical performance of these two analysers using fresh plasma samples with or without a risk of interference due to hemolysis or lipemia. For plasma samples without interference, acceptable agreement was observed for prothrombin time (PT) (n = 55), activated partial thromboplastin time (APTT) (n = 56), fibrinogen (n = 56) and factor II (n = 43) with R² of 0.907, 0.963, 0.979 and 0.968 respectively. For factor V (n = 43) and D-dimers (n = 45), agreement was less acceptable, with respective R² of 0.756 and 0.887, but with no clinical impact. For hemolysed samples, acceptable results were observed for PT, fibrinogen and D-dimers, but three results were clinically discordant for APTT, and STA R Max3 offered greater robustness for processing highly lipemic samples.","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 4","pages":"387-403"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Neurocryptococcosis waiting to be diagnosed]. [等待诊断的神经隐球菌病]。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1905

Ahmed Ashrin, Suzanne Tran, Ariane Gavaud, Marine Armand, Lauriane Geoffray, Magali Le Garff-Tavernier, David Saadoun, Cécile Nabet, Elise Sourdeau

引用次数: 0

Blastic plasmacytoid dendritic cell neoplasm or CD4+ CD56+ acute myeloid leukemia: A case report. 大疱性类树突状细胞肿瘤或 CD4+ CD56+ 急性髓性白血病：病例报告

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1907

Sameh Neji, Fatma Ben Lakhal, Sarra Fekih Salem, Ons Ghali, Hend Ben Neji, Meriem Achour, Wijdene El Borgi, Emna Gouider

{"title":"Blastic plasmacytoid dendritic cell neoplasm or CD4+ CD56+ acute myeloid leukemia: A case report.","authors":"Sameh Neji, Fatma Ben Lakhal, Sarra Fekih Salem, Ons Ghali, Hend Ben Neji, Meriem Achour, Wijdene El Borgi, Emna Gouider","doi":"10.1684/abc.2024.1907","DOIUrl":"10.1684/abc.2024.1907","url":null,"abstract":"Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an extremely rare disease that originates from dendritic cells, characterized by co-expression of CD4 and CD56 without any other lineage-specific markers. It is associated with a poor prognosis. Previously, it was referred to by several names, including blastic NK-cell lymphoma, agranular CD4+ natural killer cell leukemia, and agranular CD4+CD56+ hematodermic neoplasm. The various nomenclatures and its evolution reflect the uncertainty of its histogenesis and the challenges involved in describing this hematopoietic neoplasm. Diagnosis challenge is due to similarities with CD4+CD56+ acute myeloid leukemia (AML) and histiocytic sarcoma (HS) immunophenotypic and histopathological features. We report a case of a 42-year-old male who presented with skin lesions and pancytopenia. While biologists suspected the diagnosis of BPDCN or CD4+ CD56+ AML based on the flow cytometry (FCM), anatomic pathologists retained the diagnosis of HS. The patient didn't respond to a systemic combination chemotherapy regimen and passed away rapidly. BPDCN diagnosis requires careful and exhaustive analyses in order to formulate the most appropriate therapeutic plan and to improve its prognosis.","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 4","pages":"405-412"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of a single specimen pneumatic tube system in the clinical laboratory. 验证临床实验室中的单个标本气动管系统。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1912

Xu-Cai Dong, Bin Li, Xiao-Ke Hao, Chun-Feng Li, Xian-Fei Zeng

{"title":"Validation of a single specimen pneumatic tube system in the clinical laboratory.","authors":"Xu-Cai Dong, Bin Li, Xiao-Ke Hao, Chun-Feng Li, Xian-Fei Zeng","doi":"10.1684/abc.2024.1912","DOIUrl":"10.1684/abc.2024.1912","url":null,"abstract":"The single-specimen pneumatic tube (PTS) is a commonly used rapid specimen delivery system in modern clinical laboratories. However, its impact on sample integrity and laboratory test results remains controversial. The installation and configuration of single-specimen PTS are unique to their institution. We sought to validate our single-specimen PTS by comparing routine chemistry, immunology, and hematology results with a repeat sample integrity index for manual transport. In 2023, 30 employees were randomly selected from the company medical examination, and three tubes of procoagulant serum samples and three tubes of EDTA anticoagulant blood samples were collected from each of them. Group A uses a single specimen PTS at 8 m/s, Group B uses a single specimen PTS at 15 m/s, and Group C uses manual transfer. Specimens from all three groups were simultaneously analysed for ALT, AST, TG, TC, LDL, K, NA, CI, TSH, hs-cTnT, NSE, Cyfra21-1 and haematological analysis. The differences between the three groups of NSE and Cyfra21-1 were statistically significant (P < 0.05). The differences of the rest of the items were not statistically significant. The difference in NSE was not statistically significant between groups A and B (P = 0.401), B and C, and C and A (P < 0.05). The difference in Cyfra21-1 was not statistically significant between groups A and B (P = 0.897), B and C (P = 0.052), and C and A (P = 0.145). Individual sample PTS should be validated for testing prior to use to ensure the results' accuracy.","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 4","pages":"439-445"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Methadone-induced central adrenal insufficiency: a case report]. [美沙酮诱发中枢肾上腺功能不全：病例报告]。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1908

Thi Ngoc Mai Tran, Sylvain Roumeau, Antoine Puravet, Vincent Sapin, Damien Bouvier, Charlotte Oris

引用次数: 0

[SFBC Working Group on sources of errors in laboratory medicine: objectives and key areas of work]. [SFBC 实验室医学错误源工作组：目标和主要工作领域]。

Annales de biologie clinique Pub Date : 2024-09-19 DOI: 10.1684/abc.2024.1911

Mustapha Zendjabil, Hichem Assami, Valéry Bourbonneux, Valéry Brunel, Clément Capaldo, Nicolas Collet, Dorra Guergour, Guillaume Grzych, Wafa Masri, Jonathan Outreville, Véronique Raverot, Nathalie Rousseau, Charles R Lefèvre

{"title":"[SFBC Working Group on sources of errors in laboratory medicine: objectives and key areas of work].","authors":"Mustapha Zendjabil, Hichem Assami, Valéry Bourbonneux, Valéry Brunel, Clément Capaldo, Nicolas Collet, Dorra Guergour, Guillaume Grzych, Wafa Masri, Jonathan Outreville, Véronique Raverot, Nathalie Rousseau, Charles R Lefèvre","doi":"10.1684/abc.2024.1911","DOIUrl":"10.1684/abc.2024.1911","url":null,"abstract":"Laboratory medicine plays a crucial role in patient care, contributing to approximately 70 % of clinical decisions. In collaboration with clinicians, laboratory medicine specialists perform analyses that are useful for diagnosis, screening and prevention. Laboratories are known for their efficiency, which is reached through a rigorous quality system. However, errors can occur, especially given the complexity of the total testing process. These errors may lead to severe consequences, such as incorrect diagnoses or delays in treatment. Errors can occur at every stage of the total testing process, those related to the pre-analytical phase being the most prevalent. To reduce medical errors related to laboratory processes, it is essential to provide training for medical and paramedical staff, optimize production automation, and leverage technological advancements. These considerations have led to the creation of a French Working Group on Sources of Errors in Laboratory Medicine, under the aegis of the French lean society of clinical chemistry and laboratory medicine (Société Française de Biologie Clinique - SFBC). The objectives of this working group are to produce an educational handbook on sources of errors in laboratory medicine, provide training for clinical chemists, and conducting applied research projects to better understand the mechanisms behind specific errors. Ultimately, the aim is to minimize errors and enhance the quality of laboratory tests.","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 4","pages":"446-450"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0