Ludovic Bergon, Suzanne Burel, Olivier Dauwalder, Brigitte Rivière, Paul Cauquil, Mathilde Vernet, Bob Catala, Marie Isabelle Steinbach, Ibtihel Benlhaj, Josiane Boularan, Jérôme Garcia, Sarah Khatibi
{"title":"[Capnocytophaga canimorsus meningitis: no, the dog is not always man's best friend!]","authors":"Ludovic Bergon, Suzanne Burel, Olivier Dauwalder, Brigitte Rivière, Paul Cauquil, Mathilde Vernet, Bob Catala, Marie Isabelle Steinbach, Ibtihel Benlhaj, Josiane Boularan, Jérôme Garcia, Sarah Khatibi","doi":"10.1684/abc.2025.1989","DOIUrl":null,"url":null,"abstract":"<p><p>Capnocytophaga canimorsus meningitis are rare invasive infection with unpredictable outcomes. Therefore, rapid diagnosis and treatment are crucial. Here, we describe a case with an initially falsely reassuring clinical presentation. Lumbar puncture reveals purulent and inflammatory cerebrospinal fluid, but the syndromic multiplex PCR remains negative. The challenging microbiological diagnosis resulted from a meticulous examination of the CSF and the performance of a 16S rRNA PCR followed by sequencing. A thorough medical history, including close contact with dogs and identification of immunosuppression factors, is critical for diagnosis, emphasizing the importance of clinical-biological collaboration.</p>","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"83 5","pages":"1-6"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de biologie clinique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1684/abc.2025.1989","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Capnocytophaga canimorsus meningitis are rare invasive infection with unpredictable outcomes. Therefore, rapid diagnosis and treatment are crucial. Here, we describe a case with an initially falsely reassuring clinical presentation. Lumbar puncture reveals purulent and inflammatory cerebrospinal fluid, but the syndromic multiplex PCR remains negative. The challenging microbiological diagnosis resulted from a meticulous examination of the CSF and the performance of a 16S rRNA PCR followed by sequencing. A thorough medical history, including close contact with dogs and identification of immunosuppression factors, is critical for diagnosis, emphasizing the importance of clinical-biological collaboration.