American journal of Alzheimer's disease and other dementias最新文献_第2页

Facilitators and Barriers to Physical Activity Participation in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review Based on the COM-B Model. 轻度认知障碍或痴呆老年人参与体育活动的促进因素和障碍：基于COM-B模型的系统综述

IF 2.7

American journal of Alzheimer's disease and other dementias Pub Date : 2026-01-01 Epub Date: 2026-01-22 DOI: 10.1177/15333175261420561

Jiachen Han, Wan Sun, Xin Yin, Luo Wang, Fang Zhou, Shuo Wang

{"title":"Facilitators and Barriers to Physical Activity Participation in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review Based on the COM-B Model.","authors":"Jiachen Han, Wan Sun, Xin Yin, Luo Wang, Fang Zhou, Shuo Wang","doi":"10.1177/15333175261420561","DOIUrl":"10.1177/15333175261420561","url":null,"abstract":"BackgroundPhysical activity is crucial for preventing cognitive decline in elders with mild cognitive impairment (MCI) or dementia, but increasing it in this group poses challenges.ObjectiveTo summarize and update barriers and facilitators to physical activity using the COM-B (Capability-Opportunity-Motivation-Behavior) model, and examine variations across settings, cognitive levels, and stakeholders' perspectives.MethodsEight databases (PubMed, EMBASE, PsycINFO, CINAHL, Cochrane Library, China National Knowledge Network, Wanfang Data and VIP) were searched from inception to January 20, 2024. Barriers and facilitators were analyzed using directed content analysis based on the COM-B model.ResultsFrom 33 studies, 18 barriers and 15 facilitators were identified, spanning all COM-B domains, with variations across settings, cognitive levels, and stakeholders' perspectives.ConclusionThe findings provide a foundation for developing tailored physical activity promotion strategies for older adults with MCI/dementia, which should be differentiated based on residential settings, cognitive impairment levels, and stakeholders involved.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"41 ","pages":"15333175261420561"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12833146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146032067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of Sporadic Creutzfeldt-Jakob Disease in the Emergency Department. 散发性克雅氏病在急诊科的发病率

IF 2.7

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-10-25 DOI: 10.1177/15333175251391561

Ilse Murrieta-Hernández, Daniel García-Gutiérrez, Sarah Ticehurst-Corona, Enrique Piña-Rosales, Héctor Téllez-Lucero, Isaac Tetlalmatzi-Azuara, Juan Carlos López-Hernández, Mayela Rodríguez-Violante, Brenda Dzul-Garcia, Raúl Medina-Rioja

{"title":"Incidence of Sporadic Creutzfeldt-Jakob Disease in the Emergency Department.","authors":"Ilse Murrieta-Hernández, Daniel García-Gutiérrez, Sarah Ticehurst-Corona, Enrique Piña-Rosales, Héctor Téllez-Lucero, Isaac Tetlalmatzi-Azuara, Juan Carlos López-Hernández, Mayela Rodríguez-Violante, Brenda Dzul-Garcia, Raúl Medina-Rioja","doi":"10.1177/15333175251391561","DOIUrl":"10.1177/15333175251391561","url":null,"abstract":"IntroductionCreutzfeldt-Jakob disease (CJD) is a fatal prion disorder marked by rapidly progressive dementia and neuropsychiatric features. Epidemiological data in Latin America are limited, and no incidence studies exist in Mexico. This study sought to quantify CJD incidence in a neurological reference center.MethodsA cross-sectional study was conducted at the National Institute of Neurology and Neurosurgery, Mexico City, during 2023-2024. Clinical and paraclinical findings were reviewed. Incidence was calculated per 1000 emergency visits, with relative risk (RR) and 95% confidence intervals.ResultsAmong 19 003 patients, 15 fulfilled probable CJD criteria. Incidence was 0.55/1000 in 2023 and 1.01/1000 in 2024 (RR 1.83; 95% CI 0.63-5.35; P = .309). Cognitive and behavioral symptoms predominated (psychosis in 68%). MRI revealed abnormalities in all cases, most often cortical ribboning (93%).ConclusionThis first incidence study highlights the presence of CJD in specialized Mexican centers, underscoring the need for systematic surveillance and improved diagnostic access.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251391561"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12572603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Primary Caregiver: A Scoping Review of Family-Centered Dementia Caregiving Programs. 超越主要照顾者：以家庭为中心的痴呆症护理计划的范围审查。

IF 2.7

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-10-25 DOI: 10.1177/15333175251391571

Alexandra Malia Jackson, Kelly S O'Sullivan, Megan Gilligan, Raven H Weaver

{"title":"Beyond the Primary Caregiver: A Scoping Review of Family-Centered Dementia Caregiving Programs.","authors":"Alexandra Malia Jackson, Kelly S O'Sullivan, Megan Gilligan, Raven H Weaver","doi":"10.1177/15333175251391571","DOIUrl":"10.1177/15333175251391571","url":null,"abstract":"Most dementia caregiver programs focus on a single caregiver, overlooking diverse caregiving networks that include family, friends, and relatives who provide care. We conducted a scoping review of family-centered dementia caregiving programs (ie, interventions with at least 2 caregivers) to (1) describe program components; (2) identify how family members are included; (3) summarize family-level measurements used and the effectiveness of family-centered programs on these outcomes; and (4) explore if and how programs are culturally adapted. We identified 36 articles and 10 programs (individual-family programs, n = 8; multi-family group programs, n = 2). Programs included similar content and effectiveness was reported by the primary caregiver and measured at the individual level. To better support diverse caregiving networks, caregiving programs may benefit from identifying core components of caregiving programs, including best practices in engaging family caregivers, acknowledging varied family structures and the fluidity in caregiving, and measuring strengths and deficits at the family-level.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251391571"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12572605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging Adults' Perception of the Typical Dementia Patient Based on Gender and Race. 基于性别和种族的新兴成人对典型痴呆患者的认知

IF 2.7

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-09-17 DOI: 10.1177/15333175251378275

Angel I M Collie, Jody S Nicholson, Curtis E Phills

引用次数: 0

Risk Factors Profile in Dementia Patients at a Tertiary Care Hospital in Nepal: A Cross-Sectional Study. 尼泊尔三级医院痴呆患者的危险因素概况：一项横断面研究

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-03-23 DOI: 10.1177/15333175251328472

Omkar Dhungel, Pawan Sharma, Nidesh Sapkota

引用次数: 0

Predicting and Evaluating Cognitive Status in Aging Populations Using Decision Tree Models. 使用决策树模型预测和评估老年人的认知状态。

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-05-05 DOI: 10.1177/15333175251339730

Zhidi Luo, Stella Ping Wang, Emily H Ho, Lihua Yao, Richard C Gershon

{"title":"Predicting and Evaluating Cognitive Status in Aging Populations Using Decision Tree Models.","authors":"Zhidi Luo, Stella Ping Wang, Emily H Ho, Lihua Yao, Richard C Gershon","doi":"10.1177/15333175251339730","DOIUrl":"https://doi.org/10.1177/15333175251339730","url":null,"abstract":"Objective: To improve the identification of cognitive impairment by distinguishing normal cognition (NC), mild cognitive impairment (MCI), and Alzheimer's disease (AD). Methods: A recursive partitioning tree model was developed using ARMADA data and the NIH Toolbox, a multidimensional health assessment tool. It incorporated demographic and clinical assessment variables to predict NC, MCI, and AD. Model performance was evaluated using AUC, precision, recall, and F1 score. Robustness was tested through 5-fold cross-validation, sensitivity, scenario, and subgroup analyses. Results: The model achieved macro-AUC and micro-AUC scores of 0.92 and 0.91 (training) and 0.89 and 0.86 (testing). Key predictors included the Picture Sequence Memory Test and List Sorting Working Memory Test. Cross-validation yielded 70.22% accuracy and a Kappa of 0.52. Conclusion: Machine learning effectively uses a small set of assessments to distinguish NC, MCI, and AD, offering a valuable tool to support clinical decision-making. Future research should validate this model across diverse populations.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251339730"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12056332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics. 利用深度学习和放射组学自动检测白质高强度患者的认知障碍。

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-03-14 DOI: 10.1177/15333175251325091

Junbang Feng, Xingyan Le, Li Li, Lin Tang, Yuwei Xia, Feng Shi, Yi Guo, Yueqin Zhou, Chuanming Li

{"title":"Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics.","authors":"Junbang Feng, Xingyan Le, Li Li, Lin Tang, Yuwei Xia, Feng Shi, Yi Guo, Yueqin Zhou, Chuanming Li","doi":"10.1177/15333175251325091","DOIUrl":"10.1177/15333175251325091","url":null,"abstract":"White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH patients from hospital 2 were used as an external validation set. Cognitive status was determined based on neuropsychological assessment results. A deep learning convolutional neural network of VB-Nets was used to automatically identify and segment whole-brain subregions and WMH. The PyRadiomics package in Python was used to automatically extract radiomic features from the WMH and bilateral hippocampi. Delong tests revealed that the random forest model based on combined features had the best performance for the detection of cognitive impairment in WMH patients, with an AUC of 0.900 in the external validation set. Our results provide clinical doctors with a reliable tool for the early diagnosis of cognitive impairment in WMH patients.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251325091"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional and Non-traditional Caregivers Define "Family" and Caregiving Obligations. 传统和非传统照顾者定义“家庭”和照顾义务。

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-07-14 DOI: 10.1177/15333175251357328

Sarah E Patterson, Kelsi Caywood, Samantha M Pantelic, Olivia Morreale

引用次数: 0

Examining Care Network Composition by Nativity Status in Adults Living With Cognitive Impairment. 成人认知障碍患者出生状况对护理网络构成的影响。

IF 2.7

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-10-09 DOI: 10.1177/15333175251387431

Sophia Tsuker, Rebecca George, Wenjing Li, Wenhua Lai, Amanda N Leggett

{"title":"Examining Care Network Composition by Nativity Status in Adults Living With Cognitive Impairment.","authors":"Sophia Tsuker, Rebecca George, Wenjing Li, Wenhua Lai, Amanda N Leggett","doi":"10.1177/15333175251387431","DOIUrl":"10.1177/15333175251387431","url":null,"abstract":"Foreign-born people living with cognitive impairment (PLwCI) and their family caregivers may have distinct caregiving networks compared to their U.S.-born counterparts. Data is drawn from the 2022 wave of the National Health and Aging Trends Study. Descriptive statistics and mean difference tests were run by native and foreign-born PLwCI. Linear and logistic regressions were run controlling for foreign-born PLwCI demographics with categorized time in the U.S. as the predictor of network characteristics. Foreign-born PLwCI networks were more likely to have a daughter caregiver and engage in household task-sharing, but less likely to have a spouse and non-family caregiver. In adjusted regressions, residing in the U.S. for less than 30 years was associated with greater odds of having a daughter and generalist in network, and greater task-sharing in household and self-care/mobility domains, relative to those residing over 50 years. Results underscore the importance of acculturation in shaping care networks among PLwCI.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251387431"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alzheimer's Disease Dementia Prevalence in the United States: A County-Level Spatial Machine Learning Analysis. 美国阿尔茨海默病痴呆患病率：县级空间机器学习分析。

American journal of Alzheimer's disease and other dementias Pub Date : 2025-01-01 Epub Date: 2025-04-21 DOI: 10.1177/15333175251335570

Abolfazl Mollalo, George Grekousis, Hermes Florez, Brian Neelon, Leslie A Lenert, Alexander V Alekseyenko

{"title":"Alzheimer's Disease Dementia Prevalence in the United States: A County-Level Spatial Machine Learning Analysis.","authors":"Abolfazl Mollalo, George Grekousis, Hermes Florez, Brian Neelon, Leslie A Lenert, Alexander V Alekseyenko","doi":"10.1177/15333175251335570","DOIUrl":"https://doi.org/10.1177/15333175251335570","url":null,"abstract":"A growing body of literature has examined the impact of neighborhood characteristics on Alzheimer's disease (AD) dementia, yet the spatial variability and relative importance of the most influential factors remain underexplored. We compiled various widely recognized factors to examine spatial heterogeneity and associations with AD dementia prevalence via geographically weighted random forest (GWRF) approach. The GWRF outperformed conventional models with an out-of-bag R2 of 74.8% in predicting AD dementia prevalence and the lowest error (MAE = 0.34, RMSE = 0.45). Key findings showed that mobile homes were the most influential factor in 19.9% of U.S. counties, followed by NDVI (17.4%), physical inactivity (12.9%), households with no vehicle (11.3%), and particulate matter (10.4%), while other primary factors affecting <10% of U.S. counties. Findings highlight the need for county-specific interventions tailored to local risk factors. Policies should prioritize increasing affordable housing stability, expanding green spaces, improving transportation access, promoting physical activity, and reducing air pollution exposure.","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"40 ","pages":"15333175251335570"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0