[Rinsho ketsueki] The Japanese journal of clinical hematology最新文献_第7页

[Thrombopoietin-mediated regulation of hematopoietic stem cells]. [血小板生成素介导的造血干细胞调节]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.872

Ayako Nakamura-Ishizu

引用次数: 0

[Novel therapies for multiple myeloma]. [多发性骨髓瘤的新疗法]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.547

Masaki Ri

引用次数: 0

[Expectations and challenges for clinical application of cancer genome panels in acute myeloid leukemia]. [在急性髓性白血病中临床应用癌症基因组面板的期望与挑战]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.343

SungGi Chi

引用次数: 0

[Recent findings and advances in treatment of chronic myeloid leukemia]. [慢性骨髓性白血病治疗的最新发现和进展]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.385

Tomoiku Takaku

引用次数: 0

[Usefulness of web-based application for health surveys before and after peripheral blood stem cell harvest from healthy donors]. [健康捐献者外周血干细胞采集前后健康调查网络应用的实用性]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.321

Yosuke Makuuchi, Hiroshi Okamura, Yukari Umemoto, Akinori Nishikawa, Rie Tanaka, Akari Sato, Kazuki Sakatoku, Kentaro Ido, Mirei Horiuchi, Masatomo Kuno, Teruhito Takakuwa, Mitsutaka Nishimoto, Yasuhiro Nakashima, Mika Nakamae, Shingo Yano, Masayuki Hino, Hirohisa Nakamae

{"title":"[Usefulness of web-based application for health surveys before and after peripheral blood stem cell harvest from healthy donors].","authors":"Yosuke Makuuchi, Hiroshi Okamura, Yukari Umemoto, Akinori Nishikawa, Rie Tanaka, Akari Sato, Kazuki Sakatoku, Kentaro Ido, Mirei Horiuchi, Masatomo Kuno, Teruhito Takakuwa, Mitsutaka Nishimoto, Yasuhiro Nakashima, Mika Nakamae, Shingo Yano, Masayuki Hino, Hirohisa Nakamae","doi":"10.11406/rinketsu.65.321","DOIUrl":"10.11406/rinketsu.65.321","url":null,"abstract":"Health surveys to assess adverse events after peripheral blood stem cell harvest (PBSCH) have conventionally been conducted by phone, but phone calls are suboptimal for conducting frequent surveys. We developed a web-based application (donor app) that enables donors to inform healthcare professionals (HCPs) of their health status as an electronic patient-reported outcome (ePRO). In this prospective observational study, we compared the usefulness of this donor app to phone calls for conducting health surveys. App users reported ePRO daily, and patients called by HCPs reported their health status at least once a week when called. The observation period was from the first administration of granulocyte colony-stimulating factor to the first follow-up visit after PBSCH, excluding the hospitalization period. Each group consisted of eight donors with a median age of 32 years (range: 19-58). Nine (56.3%) were female. There were eight related donors in the phone call group and four in the donor app group. During the observation period, HCPs obtained health status reports more frequently from app users than from phone call recipients (mean proportion of days with reports made during the observation period, 27.0% vs 53.5%; p<0.05). Average time spent by the HCPs for one follow-up and total follow-ups were both significantly shorter when the donor app was used. There were no differences in donor burden or satisfaction with donation. Our study suggests that use of a donor app could provide more detailed health survey data without increasing the burden on donors and HCPs.","PeriodicalId":93844,"journal":{"name":"[Rinsho ketsueki] The Japanese journal of clinical hematology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Challenges and strategies for improving efficacy in CAR-T therapy]. [提高 CAR-T 疗法疗效的挑战和策略]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.597

Ryosuke Uchibori

引用次数: 0

[Diagnosis and treatment of iron deficiency anemia]. [缺铁性贫血的诊断和治疗]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.503

Hiroshi Kawabata

{"title":"[Diagnosis and treatment of iron deficiency anemia].","authors":"Hiroshi Kawabata","doi":"10.11406/rinketsu.65.503","DOIUrl":"10.11406/rinketsu.65.503","url":null,"abstract":"The causes of iron deficiency anemia include blood loss, increased demand, insufficient dietary intake, and disorders affecting iron absorption. In certain circumstances, atrophic gastritis, either autoimmune or due to Helicobacter pylori infection, may contribute. On very rare occasions, iron-refractory iron deficiency anemia can develop as a consequence of TMPRSS6 mutations. Iron deficiency anemia is diagnosed by identification of microcytic hypochromic anemia with low serum ferritin levels. In cases of chronic disorders such as chronic kidney disease, chronic heart failure, and chronic inflammatory disorders, the diagnosis may also incorporate transferrin saturation. Treatment of underlying diseases is recommended along with iron supplementation. While oral iron supplements are the first choice, intravenous iron may be considered when oral administration is impractical, iron absorption is impaired, or rapid iron replenishment is necessary. Recently, high-dose intravenous iron formulations became available in Japan, but their use requires caution due to potential risks of allergic reactions, hypophosphatemia/osteomalacia, iron overload, and vascular leakage. Notably, the benefits of high-dose intravenous iron for patients with heart failure and iron deficiency are recognized in the field of cardiology. This article provides an overview, incorporating recent developments in the field of iron deficiency anemia.","PeriodicalId":93844,"journal":{"name":"[Rinsho ketsueki] The Japanese journal of clinical hematology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.53

引用次数: 0

[Kidney transplantation for end-stage renal disease after third allogeneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia]. [费城染色体阳性急性淋巴细胞白血病第三次异基因造血干细胞移植后终末期肾病的肾移植]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.7

Akihiko Nishijima, Naoki Shingai, Akihito Ohta, Kiyoko Suda, Kazuya Omoto, Shinya Ishida, Kosuke Yoshioka, Shuhei Kurosawa, Yutaro Hino, Yasushi Senoo, Aiko Igarashi, Gaku Oshikawa, Atsushi Hamamura, Takashi Toya, Hiroaki Shimizu, Yuho Najima, Takeshi Kobayashi, Kyoko Haraguchi, Yoshiki Okuyama, Kazuteru Ohashi, Noriko Doki

{"title":"[Kidney transplantation for end-stage renal disease after third allogeneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia].","authors":"Akihiko Nishijima, Naoki Shingai, Akihito Ohta, Kiyoko Suda, Kazuya Omoto, Shinya Ishida, Kosuke Yoshioka, Shuhei Kurosawa, Yutaro Hino, Yasushi Senoo, Aiko Igarashi, Gaku Oshikawa, Atsushi Hamamura, Takashi Toya, Hiroaki Shimizu, Yuho Najima, Takeshi Kobayashi, Kyoko Haraguchi, Yoshiki Okuyama, Kazuteru Ohashi, Noriko Doki","doi":"10.11406/rinketsu.65.7","DOIUrl":"10.11406/rinketsu.65.7","url":null,"abstract":"An 18-year-old man underwent allogenic bone marrow transplantation (BMT) for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL). Ph+ALL relapsed 3 months after the first BMT, and the patient underwent a second BMT. However, Ph+ALL relapsed 4 months after the second BMT, and he received a haploidentical peripheral blood stem cell transplantation (haplo-PBSCT) from his father. Molecular complete remission was confirmed 29 days after haplo-PBSCT. However, the patient needed dialysis for end-stage renal disease due to thrombotic microangiopathy 3 years and 2 months after haplo-PBSCT. He received a kidney transplantation from his father 7 years and 10 months after haplo-PBSCT, and got off dialysis after the kidney transplantation. Immunosuppressive therapy with methylprednisolone, tacrolimus, and mycophenolate mofetil was started for kidney transplantation, but the dose of immunosuppressive agents was reduced successfully without rejection soon after kidney transplantation. The patient has maintained long-term remission since the haplo-PBSCT, and his kidney function was restored by the kidney transplantation from his father.","PeriodicalId":93844,"journal":{"name":"[Rinsho ketsueki] The Japanese journal of clinical hematology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Role of aberrant RNA splicing in acquired sideroblastic anemia]. [异常 RNA 剪接在获得性红细胞性贫血中的作用]。

[Rinsho ketsueki] The Japanese journal of clinical hematology Pub Date : 2024-01-01 DOI: 10.11406/rinketsu.65.222

Tetsuro Ochi

引用次数: 0