Journal of surgical protocols and research methodologies最新文献

{"title":"Robotic surgery: an evolution in practice","authors":"E. Goh, T. Ali","doi":"10.1093/jsprm/snac003","DOIUrl":"https://doi.org/10.1093/jsprm/snac003","url":null,"abstract":"","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45486818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-based surgery and collaborative research","authors":"Khalid Hussain, J. Al Shakarchi, Tariq Ali, V. Dewan","doi":"10.1093/jsprm/snab011","DOIUrl":"https://doi.org/10.1093/jsprm/snab011","url":null,"abstract":"","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48819222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemotherapy vs radiotherapy in the treatment of primary cutaneous malignancies or cutaneous metastases from primary solid organ malignancies: a protocol for a systematic review and meta-analysis","authors":"Angus E. McMillan, Luke McElroy, L. O’Toole, P. Matteucci, J. Totty","doi":"10.1093/jsprm/snac005","DOIUrl":"https://doi.org/10.1093/jsprm/snac005","url":null,"abstract":"\u0000 Electrochemotherapy has emerged as a valuable tool in the treatment of cutaneous malignancies that are unamenable to surgical resection. Despite growing recognition and recommendation in national guidelines, to date, no Level 1 evidence exists comparing its use to radiotherapy in the management of cutaneous malignancies. A systematic review and meta-analysis will be undertaken in line with the Cochrane Handbook and Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement and checklist. A comprehensive search strategy will be applied to MEDLINE, Embase, CINAHL, CENTRAL and ClinicalTrials.gov from the time period from inception to December 2021. Supplementary searches of the grey literature will also be undertaken. Studies in humans which compare treatment with electrochemotherapy to radiotherapy and report tumour response with at least a 4-week follow-up will be eligible. Studies will be included regardless of publication language or country of origin. Screening of studies and data extraction will be undertaken independently by two authors. Our primary outcome will be tumour volume response according to Response Evaluation Criteria in Solid Tumors. We will also extract any secondary outcomes reported, such as patient-reported outcome measures, pain, toxicity/adverse events and progression-free survival. Included studies will be assessed for risk of bias using recognized tools. Evidence quality will be appraised using the Grading of Recommendations, Assessment, Development and Evaluation approach. If studies are of acceptable clinical homogeneity and suitable data is extracted, a meta-analysis will be performed. If adequate data are present, various subgroup analyses will be performed. Publication bias will be assessed using a funnel plot and Egger’s test.\u0000 PROSPERO CRD42021285415","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42507124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A joint effort: collaboration between surgeons and sports physicians can streamline return to play in elite athletes","authors":"Manroy Sahni, C. Speers, G. Bhogal","doi":"10.1093/jsprm/snac001","DOIUrl":"https://doi.org/10.1093/jsprm/snac001","url":null,"abstract":"","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42392881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of evidence-based surgery, surgical protocols and research methodologies","authors":"Tariq Ali, J. A. Shakarchi, V. Dewan, Khalid Hussain","doi":"10.1093/jsprm/snab003","DOIUrl":"https://doi.org/10.1093/jsprm/snab003","url":null,"abstract":"The objective of clinical research is to establish ethically and methodologically sound evidence that can aid clinical decision-making, inform ongoing research and add to the existing body of knowledge. Surgical clinical research can encompass a wide spectrum of activities, from the assessment of technical innova-tions, determining the efficacy of pharmaceuticals and medical devices, evaluating preventative interventions or validating diagnostic and prognostic tools; the list is not exhaustive. Due to its interventional nature, clinical research in surgery can be an exceptionally complex endeavour to undertake. Investigators may encounter challenges that are less problematic in other forms of biomedical research. Blinding is a very obvious example:researchinganoperativeinterventioncouldpotentially unblind the subject and double blinding is impossible to achieve, as the investigator needs perform the procedure.The prospect of placebo surgery, although there are notable studies that employ this technique, also opens up some very serious ethical considerations. Is ‘doing harm’ for the sake of a study acceptable? Is this any less ethical than omitting a treatment where one exists? Furthermore, standardizing an operative approach may be difficult to achieve amongst different operators let alone between multiple centres. Indeed, the expertise that are present during particular periods of time or located in certain centres may drastically alter any outcome that may be investigated. These challenges can only be tackled if investigators thoroughly consider the ethical, scientific and methodological aspects oftheir proposed study.The studyprotocol istheintegral document that defines the research question and outlines its objectives and outcome measures. The protocol should include but not be limited to the following: the justification for the research, the characteristics of the population that is to be studied, details on data management and analysis, assessment of the independent and confounding variables as well as the ethical considerations and quality assurance methodology. This document can be used to evaluate and regulate the","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44544199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to set up and run a surgical research laboratory","authors":"A. Beggs","doi":"10.1093/jsprm/snab007","DOIUrl":"https://doi.org/10.1093/jsprm/snab007","url":null,"abstract":"\u0000 Laboratory fundamental science research has lost prominence in recent years, with alternate academic careers paths being available to surgeons. Strengthening fundamental science in surgery has never been so vital and so this article sets out to discuss the steps needed to set up and develop a surgical research laboratory.","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45362471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the global outcomes of traumatic brain injury in low-, middle- and high- income countries: a prospective, global neurosurgery, multicenter cohort study (Global NeuroSurg 1 Study Protocol)","authors":"A. Negida, Zoe E. Teton, Brittany Stedelin, Caleb S Nerison, Hieder Al-Shami, A. Hegazy, Ahmed M. Raslan","doi":"10.1093/jsprm/snab002","DOIUrl":"https://doi.org/10.1093/jsprm/snab002","url":null,"abstract":"\u0000 Globally, traumatic brain injury (TBI) affects 69 million individuals every year. However, there are wide variations in the management of TBI across low-, middle- and high-income countries which reflects on the outcomes of TBI worldwide. This study aims to provide a comprehensive global picture of the surgical and nonsurgical management and outcomes of TBI. The Global NeuroSurg 1 study is a prospective international multicentre cohort study conducted in self-selected registered centers. Any hospital receiving and managing TBI patients is eligible to participate (registration through www.globalneurosurg.org). After obtaining institutional ethical approvals, collaborator teams collect consecutive TBI patient data within any 2 weeks from the 1 June 2019 to the 30 September 2021 with 90 days of follow-up for every patient. Data items include (1) patient demographics, (2) TBI timing, severity and mechanism, (3) clinical status of the patient, (4) radiographic findings, (5) surgical and nonsurgical management and (6) patient survival and Glasgow outcome score. All data are submitted to the secure RedCap system of Oregon Health and Science University, OR. Binary logistic regression analysis will be conducted to evaluate the predictors of 30-day mortality. The odds ratios and the corresponding 95% confidence intervals will be calculated for each variable. Then variables that are independently contributing to the mortality will be selected and examined. Study ethical approvals or ethical approval waivers are obtained from all participating centers. All collected data are kept confidential and will be used only for the purpose of this study.","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42097022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The British Orthopaedic Oncology Management audit protocol","authors":"James E. Archer, Govind S Chauhan, Khabab Osman, Calum Thomson, V. Dewan, R. Nandra, J. Stevenson","doi":"10.1093/jsprm/snab005","DOIUrl":"https://doi.org/10.1093/jsprm/snab005","url":null,"abstract":"\u0000 Metastatic bone disease (MBD) is a frequently encountered condition in trauma and orthopaedic practice, and delayed or inappropriate management may lead to worse oncological outcomes, dysfunction and reoperation. Updated guidance from the British Orthopaedic Oncology Society (BOOS) and British Orthopaedic Association (BOA), in 2015, aimed to raise awareness of such risks and to set clear standards for the provision of care in MBD patients. However, it is unclear whether these recommendations have been routinely adopted into clinical practice. BOOS and BOA aim to revise and update this guidance, and British Orthopaedic Association Standard for Trauma (BOAST) guidelines relating to MBD management are due to be published. The aim of this collaborative audit is to evaluate and benchmark current practice in the management of MBD prior to the publication of these BOAST guidelines, providing a baseline comparison for further future re-audit.","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43348059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study protocol for ELIXIR: an evaluation of learning and exposure to the undergraduate Interventional Radiology curriculum","authors":"F. Osman, J. Koe, E. Lau, D. Nagaraj, H. Ng, A. Ng, A. Asif, R. Uberoi, V. Chan, T. Wah","doi":"10.1093/jsprm/snab006","DOIUrl":"https://doi.org/10.1093/jsprm/snab006","url":null,"abstract":"\u0000 \u0000 \u0000 Despite the initiation of a suggested undergraduate curriculum for Interventional Radiology (IR) by the British Society of Interventional Radiology, there is still a lack of exposure to IR amongst medical students and junior doctors. It is unclear how much of the proposed curriculum is implemented in the undergraduate curricula of the respective medical schools in the UK.\u0000 \u0000 \u0000 \u0000 This is a cross-sectional study that aims to evaluate the level of awareness of IR as a subspecialty amongst medical students in the UK. All final year students from the 34 UK medical universities that award primary medical qualifications are eligible for the study. A student representative from each university will be recruited through a social media drive to distribute a survey. The online questionnaire is divided into five different sections; (i) Particulars, (ii) Basic knowledge on IR, (iii) Medical School Curriculum and Exposure, (iv) Career Prospects and (v) Satisfaction with Medical School Curriculum, with the intent of gauging their exposure and understanding of IR throughout the years of medical school and assessing their perceptions of IR as a potential career choice.\u0000","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47720579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study protocol for a national retrospective review of femoral periprosthetic fracture management. Is there variation in practice?","authors":"A. Nasser, Govind S Chauhan, Khabab Osman, Saroop Nandra, R. Nandra, A. Mahmood","doi":"10.1093/jsprm/snab004","DOIUrl":"https://doi.org/10.1093/jsprm/snab004","url":null,"abstract":"\u0000 \u0000 \u0000 The incidence of femoral periprosthetic fractures (PPFs) in the UK is on the rise. This rising incidence presents a clinical and an economic burden on the national health care services. There is also uncertainty about the most effective treatment modality for femoral PPFs, as well as a lack of evidence for a standardized management approach. We aimed to identify the true incidence and any variation in the management of femoral PPFs nationally.\u0000 \u0000 \u0000 \u0000 This multicentre national collaborative study has been designed by a trainee led research network in collaboration with a well-established university research organization. Data will be collected from participating centres over a period of 10 years (2010–2019). All adults presenting with a femoral PPF will be identified, and the mode of treatment for each fracture subtype will be recorded. Other measures will evaluate patient and treatment variables, objective and subjective outcome measures. Univariate and multivariate regression analyses will be used, as well as the coefficient of determination (R) in an attempt to measure the degree to which the models could explain the variation in management.\u0000 \u0000 \u0000 \u0000 This multicentre national project was approved by the local clinical governance department at each participating hospital site. The results of this study will be submitted to international peer reviewed journals and appropriate national and international conferences.\u0000","PeriodicalId":93590,"journal":{"name":"Journal of surgical protocols and research methodologies","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48373427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}