Journal of hazardous materials letters最新文献

Occurrence and transformation of antimony in a full-scale municipal wastewater treatment plant 某大型城市污水处理厂锑的发生与转化

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2025-12-24 DOI: 10.1016/j.hazl.2025.100173

Yunao Zhao , Dawei Yu , Yuansong Wei

{"title":"Occurrence and transformation of antimony in a full-scale municipal wastewater treatment plant","authors":"Yunao Zhao , Dawei Yu , Yuansong Wei","doi":"10.1016/j.hazl.2025.100173","DOIUrl":"10.1016/j.hazl.2025.100173","url":null,"abstract":"<div><div>Antimony (Sb), a key controlled heavy metal sourcing from brake pads and tires as a trending friction stabilization, is increasingly detected in urban drainage systems. However, Sb’s occurrence and transformation in wastewater treatment facilities are missing. The Sb distribution, speciation, and transformation along the wastewater treatment processes were thus investigated in a full-scale municipal wastewater treatment plant (WWTP). Results showed dissolved Sb dominated by Sb(III) (81.7 %) in the influent. Along the treatment train, a dynamic redox cycle was identified: near-complete oxidation of Sb(III) to Sb(V) occurred under aerobic conditions, while substantial Sb(V) reduction and Sb(III) re-accumulation prevailed in anaerobic/anoxic zones. This transformation was governed by an interplay of abiotic factors (e.g., Fe/Mn oxides) and microbial activity, evidenced by the abundance of key functional genes (e.g., <em>arsC_gult</em>, <em>dsrA/B</em>). Consequently, Sb was efficiently removed (74.8 %) via sequestration into sludge, where it was enriched to 20.2 mg/kg. The residual fraction dominated Sb speciation in sludge (85–96 %), primarily attributed to sulfide precipitation as Sb<sub>2</sub>S<sub>3</sub> driven by microbial sulfate reduction. However, this effective removal led to significant sludge enrichment, with a geo-accumulation index (Igeo) of 3.36 indicating a moderate-to-heavy contamination risk. This study underscores that enhancing reductive conditions in terminal units is key to immobilizing Sb and highlights the need for integrated strategies to manage this emerging contaminant throughout the wastewater treatment cycle.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100173"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanism of selenite reduction in Bacillus subtilis SR41: Role of thioredoxin reductase and threshold-driven transcriptomic response 枯草芽孢杆菌SR41亚硒酸盐还原的机制：硫氧还蛋白还原酶的作用和阈值驱动的转录组反应

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2025-12-05 DOI: 10.1016/j.hazl.2025.100172

Yuanzhi Cheng , Tao Gong , Xiao Li , Jie Fu , Yuanli Jin , Lei Qiao , Luoyi Zhu , Fengqin Wang , Mingliang Jin , Zeqing Lu , Yizhen Wang

{"title":"Mechanism of selenite reduction in Bacillus subtilis SR41: Role of thioredoxin reductase and threshold-driven transcriptomic response","authors":"Yuanzhi Cheng , Tao Gong , Xiao Li , Jie Fu , Yuanli Jin , Lei Qiao , Luoyi Zhu , Fengqin Wang , Mingliang Jin , Zeqing Lu , Yizhen Wang","doi":"10.1016/j.hazl.2025.100172","DOIUrl":"10.1016/j.hazl.2025.100172","url":null,"abstract":"<div><div>Selenium, an essential trace element for humans and animals, plays critical roles in various biological processes. However, selenite, a highly toxic form of selenium, presents substantial environmental hazards. Microbial-mediated detoxification of selenite into selenium nanoparticles (SeNPs) has emerged as an eco-friendly strategy. <em>Bacillus subtilis</em> SR41, a selenite-tolerant probiotic, can biosynthesize SeNPs with an average size of 67.0 ± 0.6 nm. This study is the first to report that SR41 exhibits distinct growth patterns when exposed to selenite concentrations above or below the detoxification threshold. Through a combination of <em>in vitro</em> assays, transcriptomics, and detection of selected-gene expression levels, thioredoxin reductase (TrxR) is identified as the primary enzyme responsible for selenite reduction, rather than glutathione reductase or fumarate reductase. The selenite reduction rate of recombinant TrxR was modeled using Michaelis-Menten kinetics, with nonlinear least squares analysis yielding a <em>K</em><sub>m</sub> value of 282.5–406.7 μM and a <em>V</em><sub>max</sub> of 332.9–373.0 μM·h⁻¹ .Notably, under selenite concentrations exceeding the detoxification threshold, TrxR is upregulated 18.21-fold, while SR41 exhibits an activation of ribosome-associated genes to mitigate the toxicity. Gene knockout experiments demonstrate the indispensability of TrxR-encoding genes. This study elucidates mechanisms of microbial selenite detoxification across concentration gradients and offers insights for environmental bioremediation applications.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100172"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145737545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytoremediation and phytoscreening of micropollutants using black poplar: Integration of LC-MS/MS multiscreening and rhizospheric microbiome analysis 黑杨树微污染物的植物修复与植物筛选：LC-MS/MS多重筛选与根际微生物组分析的集成

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2025-11-24 DOI: 10.1016/j.hazl.2025.100170

Stanislava Vrchovecká , Petra Štochlová , Aday Amirbekov , Stanisław Wacławek

{"title":"Phytoremediation and phytoscreening of micropollutants using black poplar: Integration of LC-MS/MS multiscreening and rhizospheric microbiome analysis","authors":"Stanislava Vrchovecká , Petra Štochlová , Aday Amirbekov , Stanisław Wacławek","doi":"10.1016/j.hazl.2025.100170","DOIUrl":"10.1016/j.hazl.2025.100170","url":null,"abstract":"<div><div>The increasing occurrence of micropollutants, including pesticides and perfluoroalkyl substances (PFAS), in groundwater, presents a growing challenge for environmental monitoring and remediation. This study investigates the phytoremediation potential of black poplar (<em>Populus nigra</em>) in hydroponic systems as an alternative and cost-effective tool for groundwater quality monitoring and contaminant attenuation. A multiscreening analytical method based on UHPLC-MS/MS was developed and validated for the simultaneous quantification of 21 micropollutants and their degradation products in plant biomass using a combination of QuEChERS and HLB solid-phase extraction. Hydroponic exposure experiments revealed that black poplar contributed to the removal of 12–87 % of the target compounds, with accumulation primarily in root tissues. Translocation to stems and leaves was compound-specific and related to physicochemical properties such as log K<sub>ow</sub>. Root concentration factors (RCF) ranged from 0.01 to 55.53, and translocation factors (TF) from 0.01 to 4.08. In addition, 16S rRNA and ITS amplicon profiling indicated exploratory shifts in rhizospheric bacterial and fungal communities under selected micropollutants, suggesting testable links to plant–microbe interactions and contaminant attenuation. The results confirm that black poplar can be used both for phytoscreening and phytoremediation of diverse classes of micropollutants, supporting its application in integrated strategies for groundwater protection and ecological risk assessment.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100170"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145610370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxidation of polyaniline-derived carbon using microwaves for adsorptive removal of pharmaceuticals with an amino group 用微波氧化聚苯胺衍生的碳以吸附去除含有氨基的药物

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2026-01-15 DOI: 10.1016/j.hazl.2026.100176

Dae Sung Kwon , Minyoung Yoon , Sung Hwa Jhung

{"title":"Oxidation of polyaniline-derived carbon using microwaves for adsorptive removal of pharmaceuticals with an amino group","authors":"Dae Sung Kwon , Minyoung Yoon , Sung Hwa Jhung","doi":"10.1016/j.hazl.2026.100176","DOIUrl":"10.1016/j.hazl.2026.100176","url":null,"abstract":"<div><div>Carbonaceous materials, especially oxidized ones, have been frequently used as adsorbents. Oxidation of carbons has usually been carried out using ammonium persulfate/H<sub>2</sub>SO<sub>4</sub> solution under electric heating. In this work, polyaniline-derived carbons were oxidized with both the conventional method and HNO<sub>3</sub> under microwaves. The obtained carbons, after thorough characterization, were applied to the adsorptive purification of water polluted with emerging contaminants, especially basic pharmaceuticals with amino groups (like atenolol (ATNL) and diphenhydramine (DPHA)). The carbon oxidized under microwave was much more effective in the adsorption than the carbon oxidized by the conventional method using electric heating. Both the adsorbed quantities and adsorption kinetic constants increased with increasing oxidation (by microwaves) temperatures up to 100 °C. The best performing MPDC(100) was recyclable and highly competitive in the adsorption of ATNL and DPHA. The mechanism of ATNL and DPHA adsorptions over MPDC(100) was investigated by checking surface charge and adsorbed quantities under wide pH conditions. Electrostatic interaction with π-π interaction and hydrogen bonding (adsorbent: hydrogen-acceptor) was the major mechanism for the effective adsorption over MPDC(100). Finally, porous carbon with a high concentration of anionic sites like carboxylates can be suggested as an effective adsorbent to remove basic pharmaceuticals with amino groups.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100176"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Confined Fe(III) in carbon nitride shifted peroxymonosulfate activation from radical to high-valent iron pathways for efficient dioxin degradation 氮化碳中限制的铁（III）将过氧单硫酸盐活化从自由基转移到高价铁途径，以有效降解二恶英

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2026-01-19 DOI: 10.1016/j.hazl.2026.100174

Jibo Dou , Yichao Xu , Yunfei He , Ruoru Xu , Yao Yue , Feifei Chen , Yuchi Zhong , Xuetong Qu , Jiafeng Ding , Hangjun Zhang

{"title":"Confined Fe(III) in carbon nitride shifted peroxymonosulfate activation from radical to high-valent iron pathways for efficient dioxin degradation","authors":"Jibo Dou , Yichao Xu , Yunfei He , Ruoru Xu , Yao Yue , Feifei Chen , Yuchi Zhong , Xuetong Qu , Jiafeng Ding , Hangjun Zhang","doi":"10.1016/j.hazl.2026.100174","DOIUrl":"10.1016/j.hazl.2026.100174","url":null,"abstract":"<div><div>Fe-doped carbon matrices have garnered significant attention as peroxymonosulfate (PMS) activators for the removal of refractory organic pollutants. However, the role of Fe dopant in PMS activation remains unclear, especially concerning the relative contributions and reaction pathways of high-valent iron oxidations. In this study, a series of Fe-doped carbon nitride (CN) catalysts with varying iron contents was synthesized and utilized for the catalytic degradation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Results showed that Fe doping significantly enhanced PMS activation, with the highest TCDD degradation rate achieved by Fe-CN-3, exhibiting a 4.6-fold improvement. Quenching experiment revealed that increasing Fe content shifted the degradation mechanism from a radical-dominated process (76.1 %) to a Fe<sup>V</sup>=O-driven nonradical pathway (55.8 %); consequently, the Fe-CN-3/PMS system exhibited significant resistance to common environmental interferents. Theoretical calculations further confirmed that the Fe(III)-PMS interaction weakened both the O<sub>2</sub>-O<sub>3</sub> and O<sub>3</sub>-H bonds, thereby enabling their thermodynamically feasible cleavage and the subsequent generation of Fe<sup>V</sup>=O via a coupled electron-proton transfer pathway, which ultimately enhanced the electrophilic σ-attack on TCDD. These findings highlight the criticality of the metal dopant's local coordination environment in steering persulfate activation pathways, guiding the rational design of catalysts for selective oxidant generation.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100174"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waste PU-derived PDMS/ZIF-8/bentonite composite sponge for reusable oil sorption 废pu衍生PDMS/ZIF-8/膨润土复合海绵可重复使用吸油

IF 8.1

Journal of hazardous materials letters Pub Date : 2026-11-01 Epub Date: 2026-01-13 DOI: 10.1016/j.hazl.2026.100175

Minji Kim , Da Kyung Kwon , Hyeonjeong Kim , Wonseok Park , Byungjun Cha , Yeonji Yea , Yeomin Yoon , S.SD. Elanchezhiyan , Chang Min Park

{"title":"Waste PU-derived PDMS/ZIF-8/bentonite composite sponge for reusable oil sorption","authors":"Minji Kim , Da Kyung Kwon , Hyeonjeong Kim , Wonseok Park , Byungjun Cha , Yeonji Yea , Yeomin Yoon , S.SD. Elanchezhiyan , Chang Min Park","doi":"10.1016/j.hazl.2026.100175","DOIUrl":"10.1016/j.hazl.2026.100175","url":null,"abstract":"<div><div>Rapid urbanization and population growth have intensified oil pollution, highlighting the need for efficient, selective, and multifunctional oil sorbents. In this study, a cost-effective hydrophobic composite was developed from waste polyurethane (PU) sponge with a durable 3D macroporous structure. The sponge was modified via dip-coating with zeolitic imidazolate framework (ZIF-8), bentonite, and polydimethylsiloxane (PDMS) to enhance hydrophobicity. The resulting PDMS/ZIF-8/bentonite-incorporated PU (ZBPU) sponge was characterized using powder X-ray Diffraction, Fourier Transform Infrared spectroscopy, and Scanning Electron Microscopy analyses. Contact angle measurements confirmed the hydrophobicity for the prepared ZBPU-3 sponge, indicating its suitability for oil separation applications. Sorption performance was tested with canola oil, methylene blue dye, and non-aqueous phase liquids (chloroform, toluene, xylene, benzene). ZBPU-3 exhibited an oil sorption capacity of 0.97 g/cm<sup>3</sup>, about twice that of pristine PU, and maintained effective performance for up to five sorption–desorption cycles, with oil uptake governed mainly by physical interactions.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"7 ","pages":"Article 100175"},"PeriodicalIF":8.1,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated concentrations of quaternary ammonium compounds in childcare centers: A pilot study 托儿中心季铵化合物浓度升高：一项初步研究

IF 6.6

Journal of hazardous materials letters Pub Date : 2025-11-01 Epub Date: 2025-01-02 DOI: 10.1016/j.hazl.2024.100138

Yao Cheng , Zhong Lv , Erika Schreder , Min Hu , Abby Mutic , Guomao Zheng , Amina Salamova

{"title":"Elevated concentrations of quaternary ammonium compounds in childcare centers: A pilot study","authors":"Yao Cheng , Zhong Lv , Erika Schreder , Min Hu , Abby Mutic , Guomao Zheng , Amina Salamova","doi":"10.1016/j.hazl.2024.100138","DOIUrl":"10.1016/j.hazl.2024.100138","url":null,"abstract":"<div><div>Quaternary ammonium compounds (QACs) are used as antimicrobials, preservatives, and antistatic agents in cleaning, disinfecting and personal care products, and textiles. High levels of QACs have been found in indoor dust in residential homes; however, there is limited information on QAC exposure in non-residential environments serving sensitive populations, such as childcare centers. In this study, we investigated the occurrence of QACs, including benzylalkyldimethyl ammonium compounds (BACs), dialkyldimethylammonium compounds (DADMACs), and alkyltrimethylammonium compounds (ATMACs), in dust from childcare centers and estimated daily intake of QACs by toddlers in chidlcare via dust ingestion. Nineteen QACs were detected in dust with a median total QAC concentration (ΣQAC) of 150 μg/g. BACs were the most abundant QAC group found at concentrations ranging from 2.67 to 1370 μg/g (median 90.4 μg/g) and constituted 64 % of the ΣQAC concentrations. The QAC levels in dust from childcare centers were significantly higher than concentrations previosly reported in homes. The EDIs for BACs, DADMACs, and ATMACs via dust ingestion calculated based on the 95th percentile concentrations in childcare dust were up to 30 times higher than those for toddlers in residential homes. These findings demonstrate high QAC exposure in childcares, posing significant early-life exposure for toddlers.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"6 ","pages":"Article 100138"},"PeriodicalIF":6.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micropellets of Pleurotus ostreatus for copper removal: Influence of nutritional conditions and laccase activity on adsorption 平菇微球除铜：营养条件和漆酶活性对吸附的影响

IF 6.6

Journal of hazardous materials letters Pub Date : 2025-11-01 Epub Date: 2025-06-21 DOI: 10.1016/j.hazl.2025.100157

Dinay Eloisa Durán-Sequeda , Aldo Ibarra-Rondón , Pedro Fragoso-Castilla

{"title":"Micropellets of Pleurotus ostreatus for copper removal: Influence of nutritional conditions and laccase activity on adsorption","authors":"Dinay Eloisa Durán-Sequeda , Aldo Ibarra-Rondón , Pedro Fragoso-Castilla","doi":"10.1016/j.hazl.2025.100157","DOIUrl":"10.1016/j.hazl.2025.100157","url":null,"abstract":"<div><div><em>Pleurotus ostreatus</em> has emerged as a promising model for heavy metal bioremediation. Given the known role of laccases in copper oxidation, it was hypothesized that higher laccase activity would correlate with increased copper removal. This study evaluated how the composition of the culture medium influences copper adsorption and its relationship with copper-induced laccase activity in this fungus. Fungal pellets were produced in two different media, and their morphological characteristics, laccase activity, and copper removal capacity were evaluated. The results show that, contrary to expectations, pellets with more complex morphology and higher laccase activity exhibited a maximum copper loading capacity approximately six-fold lower than those produced in media with lower laccase activity. Analysis of the pellets by SEM-EDX, FTIR, and confocal microscopy revealed some physicochemical differences. Pellets with higher copper loading capacity had higher fluorescence suggesting more cell wall polysaccharide content, but lower laccase activity. These results offer a possible link between copper removal and copper-induced laccase activity associated with compositional medium for fungal culture. This finding represents a novel approach to designing and optimizing fungal biotechnological solutions in heavy metal bioremediation.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"6 ","pages":"Article 100157"},"PeriodicalIF":6.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PFAS in biosolids: Insights into current and future challenges PFAS在生物固体：洞察当前和未来的挑战

IF 8.1

Journal of hazardous materials letters Pub Date : 2025-11-01 Epub Date: 2025-09-09 DOI: 10.1016/j.hazl.2025.100163

Prashant Srivastava , Becky Macdonald

{"title":"PFAS in biosolids: Insights into current and future challenges","authors":"Prashant Srivastava , Becky Macdonald","doi":"10.1016/j.hazl.2025.100163","DOIUrl":"10.1016/j.hazl.2025.100163","url":null,"abstract":"<div><div>Biosolids, valued as nutrient-rich soil amendments, are now approached cautiously by farmers due to growing public concern, and increasingly stringent and varying per- and poly-fluoroalkyl substances (PFAS) regulatory standards across jurisdictions. PFAS concentrations in biosolids vary widely between countries and wastewater treatment plants. Inconsistent monitoring and testing protocols hinder accurate assessment and comparison across sites. The fragmented regulatory landscape, with diverse thresholds and evolving requirements, complicates compliance and long-term planning for water utilities, challenging infrastructure investment. A key issue is lack of proven, scalable PFAS treatment technologies for municipal wastewater plants. Current solutions often lack performance, cost-effectiveness, and practicality at scale. Utilities face financial burdens for monitoring and remediation while balancing other priorities, like managing emerging contaminants and reducing greenhouse gas emissions from energy-intensive processes. Effective source control to limit PFAS entry into wastewater systems is critical and cost-effective. Integrated strategies targeting multiple pollutants can optimize investments. Clear, science-based regulatory standards for PFAS in biosolids are urgently needed to guide compliance. Collaboration among utilities, academia, technology providers, and stakeholders, supported by transparent engagement, is essential for practical PFAS management solutions and rebuilding public trust. Sustainable biosolids management depends on evidence-based, interdisciplinary efforts integrating technological innovation, regulatory clarity, and socioecological resilience.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"6 ","pages":"Article 100163"},"PeriodicalIF":8.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Di(2-ethylhexyl) phthalate exposure disrupts intestinal microbiota and activates immune signaling pathways in zebrafish intestine 二（2-乙基己基）邻苯二甲酸酯暴露破坏肠道微生物群并激活斑马鱼肠道中的免疫信号通路

IF 8.1

Journal of hazardous materials letters Pub Date : 2025-11-01 Epub Date: 2025-10-28 DOI: 10.1016/j.hazl.2025.100168

Liang Lyu , Yi-Yuan Zeng , Xuan Yang , Kaoutar Abaakil , Yong-Hui Wu , Xiao-Feng Zhang

{"title":"Di(2-ethylhexyl) phthalate exposure disrupts intestinal microbiota and activates immune signaling pathways in zebrafish intestine","authors":"Liang Lyu , Yi-Yuan Zeng , Xuan Yang , Kaoutar Abaakil , Yong-Hui Wu , Xiao-Feng Zhang","doi":"10.1016/j.hazl.2025.100168","DOIUrl":"10.1016/j.hazl.2025.100168","url":null,"abstract":"<div><div>Di(2-ethylhexyl) phthalate (DEHP), a common plasticizer, exhibits environmental persistence and multisystem toxicity. With plastic production continually rising, China’s annual output exceeded 77 million tons in 2024, reflecting a 2.9 % year-on-year increase (Ministry of Industry and Information Technology). This reflects large-scale consumption and increasing environmental pressure. However, its toxic mechanisms on the intestine, a key organ for defense and metabolism, remain poorly understood. This study indicated that DEHP exposure causes damage to zebrafish intestinal tissue, resulting in a reduction in commensal bacteria such as <em>Fusobacterium</em> and <em>Cetobacterium</em>, and enrichment of <em>Allorhizobium–Neorhizobium–Pararhizobium–Rhizobium</em> and <em>Pseudomona</em>. The analysis suggested that the expression of Toll-like receptor pathways, NOD-like receptor signaling pathways, and MAPK signaling pathways related to immunity and metabolism was upregulated. In addition,genes such as <em>tlr4</em>, <em>myd88</em>, <em>nf-κb</em>, and <em>il10</em> were significantly upregulated. Together, these findings show that DEHP may raise the risk of intestinal immune injury via the TLR4/MyD88/NF-κB pathway and dysbiosis of the intestinal microbiota. This study contributes to the assessment and control of health risks associated with DEHP contamination in water.</div></div>","PeriodicalId":93463,"journal":{"name":"Journal of hazardous materials letters","volume":"6 ","pages":"Article 100168"},"PeriodicalIF":8.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145415375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0