Interventional pulmonology (Middletown, Del.)最新文献_第10页

The growing role of flexible therapheuticbroncoscopy 灵活支气管镜的作用越来越大

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3138

Blanca de Vega Sánchez, C. Vicente, Sofia Jaurrieta Largo, Vicente Roig Figueroa, S. Martínez

引用次数: 0

Transbronchial forcep and cryobiopsy of peripheral cavitary lung lesion under R-EBUS guidance in tuberculous endemic setting 结核地方性病例R-EBUS引导下肺外周腔性病变的支气管钳和低温活检

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa317

S. S. Kho, C. Chai, T. T. Tee, S. K. Chan, S. T. Tie

引用次数: 0

Therapeutic Bronchoscopy Under Extracorporeal Membrane Oxygenation (ECMO) Support: Case Series 体外膜氧合(ECMO)支持下的支气管镜治疗:病例系列

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3404

V. Thanthitaweewat, T. Sriprasart

引用次数: 0

Feasibility of endoscopic oxygen uptake measurement for target lobe selection in endobronchial valve treatment 内镜下摄氧量测定用于支气管内瓣膜治疗靶叶选择的可行性

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa5173

Jorrit B. A. Welling, K. Klooster, J. Charbonnier, E. V. Rikxoort, C. Barends, H. Kerstjens, N. T. Hacken, J. Hartman, D. Slebos

引用次数: 1

Late Breaking Abstract - Bronchial Rheoplasty For Treatment of Chronic Bronchitis: 6 Month Results from a Prospective Multi-Center Study 支气管流变成形术治疗慢性支气管炎:一项为期6个月的前瞻性多中心研究结果

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.rct448

A. Valipour, A. Ing, J. Williamson, T. Saghaie, Daniel P Steinfort, L. Irving, M. Fortin, S. Martel, G. Snell, E. Dabscheck, Jonathan Waldstreicher, W. Krimsky, S. Fernández-Bussy

{"title":"Late Breaking Abstract - Bronchial Rheoplasty For Treatment of Chronic Bronchitis: 6 Month Results from a Prospective Multi-Center Study","authors":"A. Valipour, A. Ing, J. Williamson, T. Saghaie, Daniel P Steinfort, L. Irving, M. Fortin, S. Martel, G. Snell, E. Dabscheck, Jonathan Waldstreicher, W. Krimsky, S. Fernández-Bussy","doi":"10.1183/13993003.congress-2019.rct448","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.rct448","url":null,"abstract":"Introduction: Chronic bronchitis (CB) is characterized by a productive cough due to excessive mucus production in the airways, resulting in quality of life impairment and increased exacerbation risk. Bronchial Rheoplasty (BR) is a procedure in which an endobronchial catheter applies non-thermal pulsed electric fields to the airways. Preclinical studies demonstrated epithelial ablation followed by rapid regeneration of normalized epithelium. The present study evaluated the feasibility, safety and efficacy of BR in CB patients. Methods: Prospective, multi-center study enrolling 32 patients who underwent BR under general anesthesia. Right-sided airways were treated first; the left side was treated one month later. Follow-up through 6 months included assessment of adverse events and changes in symptoms and quality of life (QOL) using the St. George’s Respiratory Questionnaire (SGRQ) and COPD Assessment Test (CAT). Results: Bronchial rheoplasty was successfully performed in all 32 patients (62.5% male, mean age 67, post-BD FEV1 64.1±20.8%, SGRQ 59.4±15.0). Respiratory serious adverse events through 6-months included COPD exacerbation (4 patients), mucosal sail (1 patient), pleural effusion (1 patient), and unrelated lung cancer (1 patient). Mean changes from baseline to 6 months in SGRQ and CAT scores were -14.0±3.4 points (p Conclusion: This study provides clinical evidence of the feasibility, safety and clinical performance of BR in symptomatic CB patients. The results suggest that BR may provide improvement in symptoms and QOL for this patient population.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91229789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Endobronchial/ Endoscopic Ultrasound Examination and Rapid On-Site Evaluation- Experience In A UK Centre 支气管内/内窥镜超声检查和快速现场评估-英国中心的经验

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa4779

P. Shetty, R. Mogal, A. Barlow, A. Maddox

{"title":"Endobronchial/ Endoscopic Ultrasound Examination and Rapid On-Site Evaluation- Experience In A UK Centre","authors":"P. Shetty, R. Mogal, A. Barlow, A. Maddox","doi":"10.1183/13993003.congress-2019.pa4779","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4779","url":null,"abstract":"Introduction: Endobronchial ultrasound (EBUS) / Endoscopic ultrasound (EUS) has become an essential investigation tool in lung malignancy. In our centre we use Rapid on-site evaluation (ROSE), which is performed by our Cytopathology team comprising a trained Biomedical Scientist and, a Cytopathologist, allows rapid assessment of adequacy, provisional diagnosis and appropriate triage of EBUS/EUS specimens. We have audited our data in our centre since the establishment of EBUS/EUS TBNA and ROSE. Methods and Results: We present here a cohort of patients with suspected lung malignancy who underwent EBUS /EUS TBNA and ROSE in our centre between from October 2013 to June 2018. A total of 295 aspirates sites from 249 patients with suspected lung malignancy were collected during this period. Mean number passes for diagnoses on ROSE was 1.4 and mean number of total nodal passes was 3.2. Mean number of nodal sites biopsied per patient was 1.18. In 253 aspirates, malignancy was confirmed as per initial ROSE assessment. 34 aspirates were suggestive of malignancy, 4 aspirates were equivocal and 4 were assessed as benign, and the final outcome of these aspirates were malignant on cell block. 26 of these patients had Next Generation Sequencing (NGS) of cytological samples and we had a success rate of 21 /26 ( 77%). 5 patient had repeat procedure for molecular analysis. Conclusion: EBUS/EUS with ROSE is effective in achieving diagnoses with fewer needle passes and reduces inadequate rate and therefore the need for repeat procedures. The samples obtained with the aid of ROSE can be maximised so that the majority of the sample can be made into a cell block for further studies.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88575435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of fiberoptic bronchoscopy procedures in the diagnostic of pulmonary tuberculosis 纤维支气管镜检查在肺结核诊断中的作用

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa4789

C. Antunes, J. Barbosa, Eva Brysch, A. Almendra, Tiago Abreu, Leonor Mota, J. Semedo, C. Bárbara

{"title":"The role of fiberoptic bronchoscopy procedures in the diagnostic of pulmonary tuberculosis","authors":"C. Antunes, J. Barbosa, Eva Brysch, A. Almendra, Tiago Abreu, Leonor Mota, J. Semedo, C. Bárbara","doi":"10.1183/13993003.congress-2019.pa4789","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4789","url":null,"abstract":"Objective: To evaluate the role of bronchial and lung biopsies in comparison to bronchoalveolar lavage (BAL) in patients with suspicion of pulmonary tuberculosis (TB). Methods: Three-year retrospective study with 372 patients with clinical and/or radiological suspicion of TB that underwent bronchoscopy. BAL was performed in all patients, bronchial biopsies (BB) in 25 (6.7%) and transbronchial lung biopsies(TBLB) in 98 (26.3%). BAL samples were submitted to microbiological and cytological analysis, whereas BB and TBLB samples were presented to mycobacterial examination and culture and histopathological examination. Results: Of the 372 patients, 161 (43.3%) were diagnosed by bronchoscopy subsidiaries techniques: bacterial and fungal infections in 95 (25.5%); pulmonary tuberculosis in 48 (12.9%); lung cancer in 9 (2.4%); non-infectious granulomatous disease in 6 (1.6%); and nontuberculous mycobacterial infections in 3 (0.8%). In the TB group (n=48), BAL was diagnostic in 46 patients (44 positive BAL culture and 2 positive PCR test); BB where positive in 7 cases and TBLB in 5 cases. All patients with positive BB had bronchial mucosa abnormalities and in 2 patients it was the only positive result for TB. BB and BPTB accounted for 7 and 18 alternative results, respectively. Minor post-procedure complications occurred in only 1.9% of the cases. Conclusions: Despite not significantly impacting TB diagnosis, bronchial and lung biopsies facilitated the differential diagnosis with other pulmonary diseases.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85997017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The value of lobar ventilation and perfusion in selecting targeted lobe for Endoscopic Lung Volume Reduction in COPD 肺叶通气灌注在COPD内镜下肺减容术中选择靶肺叶的价值

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa5168

Li Yang, N. Hersch, K. Ho-Shon, Ciaan Perrera, J. Williamson, A. Ing

引用次数: 1

Endobronchial valve treatment in patients with severe emphysema due to alpha-1 antitrypsin deficiency α -1抗胰蛋白酶缺乏所致严重肺气肿的支气管内瓣膜治疗

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa4800

A. Delage, D. Hogarth, Michael A. Zgoda, M. Reed

{"title":"Endobronchial valve treatment in patients with severe emphysema due to alpha-1 antitrypsin deficiency","authors":"A. Delage, D. Hogarth, Michael A. Zgoda, M. Reed","doi":"10.1183/13993003.congress-2019.pa4800","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4800","url":null,"abstract":"Alpha-1 Antitrypsin Deficiency (AATD) an inherited disorder raises the risk for lung disease and often leads to emphysema. We report on the 6 & 12-month results of the AATD arm of the EMPROVE study. 20 AATD subjects on optimal medical management with hyperinflation, severe dyspnea were treated with SVS valves at 12 centers. Target lobe selection was done using high resolution computed tomography. Targeted lobe was a lower lobe in 85% and an upper lobe in 15% of patients. A mean of 4.4 valves per patient were used to isolate the target lobe, with an average procedure time of 20 minutes. Results are presented as baseline and mean changes in FEV1, Target Lobe Volume (TLV), disease specific quality of life measures – St. George’s Respiratory Questionnaire (SGRQ), modified Medical Research Council dyspnea score (mMRC), and COPD Assessment Test (CAT) and exercise capacity measured by 6-minute walk distance (6MWD). Changes at 6 and 12 months are shown in table 1. Through 12-months, there was one death. Most frequent serious adverse events were COPD exacerbation (15%), pneumonia (15%) and pneumothorax (20%). Implantation of the SVS in AATD patients with severe emphysema provides clinically meaningful improvements in FEV1, target lobe volume reduction quality of life parameters and exercise capacity, with an acceptable safety profile.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86354496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Cryobiopsy: a paradigm shift in the invasive diagnosis of IPF 冷冻活检:IPF侵入性诊断的范式转变

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3110

S. Tomassetti, A. Arcadu, M. Marchi, C. Ravaglia, S. Puglisi, Aurora Mendez, F. Carriço, A. Cavazza, G. Rossi, T. Colby, S. Piciucchi, B. Ley, H. Collard, J. Ryu, C. Gurioli, L. Donati, M. Bosi, A. Dubini, V. Poletti

引用次数: 0