Azeem Rathore, Cameron Kahn, Sawyer J. Bawek, A. Bajwa
{"title":"Robotic-assisted bronchoscopy for peripheral pulmonary lesions: A single-center experience of the Ion platform","authors":"Azeem Rathore, Cameron Kahn, Sawyer J. Bawek, A. Bajwa","doi":"10.46439/pulmonology.1.004","DOIUrl":"https://doi.org/10.46439/pulmonology.1.004","url":null,"abstract":"Rationale: The diagnostic yield of electromagnetic navigational bronchoscopy to access lung lesions remains low. The multicenter NAVIGATE study showed the diagnostic yield to be 71% for lesions up to 3 cm and 67% for lesions up to 2 cm. The introduction of robotic-assisted navigational platforms may overcome some of the traditional barriers encountered with previous approaches. We aim to assess the navigational and diagnostic yield of the Ion™ endoluminal system (Intuitive Surgical, Inc., Sunnyvale, California) regarding pulmonary lesions that could not previously be biopsied using conventional white light bronchoscopy. \u0000\u0000Methods: We retrospectively reviewed and analyzed data from our first 76 consecutive robotic-assisted navigational bronchoscopy (RAB) cases performed by a single proceduralist at our single center between March 11, 2020, to November 25, 2020. Secondary endpoints included the safety of the platform, such as incidences of pneumothoraces and significant bleeding events.\u0000\u0000Results: The ability to localize the lesion using the shape sensing technology was 100% (n=76). Navigational success, as determined by lesion visualization using radial endobronchial ultrasound confirmation, was 76% (n=58) of the nodules. The additional use of 2D-fluoroscopy for needle-in-lesion guidance and Rapid Onsite Evaluation to assess for adequate tissue sampling resulted in a diagnostic yield of 92% (n=70). There was a 0% complication rate for pneumothorax and significant bleeding events in the postoperative phase.\u0000\u0000Conclusions: Our study supports the current literature regarding the safety and efficacy of the Ion™ RAB for use in obtaining biopsy of peripheral lung lesions. Depending on the definition of navigational success, based on our results, the Ion™ RAB is comparable to or better than flexible bronchoscopy. The diagnostic yield is comparable to or better than flexible bronchoscopy but slightly lower than the gold standard computed tomography-guided transthoracic biopsy (CTTB) for peripheral lung lesions. However, in contrast to CTTB, the Ion™ RAB has lower complication rates for pneumothoraces and major bleeding. Further studies are needed to directly compare the current two robotic systems with a third system, Galaxy System™ by Noah Medical that is pending FDA approval.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87323603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between the prevalence of obstructive lung disease and the use of aspirin in a diabetic population","authors":"M. Ramos-Nino, Charles D MacLean, B. Littenberg","doi":"10.46439/pulmonology.1.002","DOIUrl":"https://doi.org/10.46439/pulmonology.1.002","url":null,"abstract":"Background: Many diabetic patients take a daily low-dose of aspirin because they are two to three times more likely to suffer from heart attacks and strokes, but its role in obstructive lung diseases is less clear. Methods: A total of 1,003 subjects in community practice settings were interviewed at home. Patients self-reported their personal and clinical characteristics, including any history of obstructive lung disease (including COPD or asthma). Current medications were obtained by the direct observation of medication containers. We performed a cross-sectional analysis of the interviewed subjects to assess for a possible association between obstructive lung disease history and the use of aspirin. Results: In a multivariate logistic regression model, a history of obstructive lung disease was significantly associated with the use of aspirin even after correcting for potential confounders, including gender, low income (<USD 30,000/year), number of comorbidities, number of medications, cigarette smoking, and alcohol problems (adjusted odds ratio = 0.67, P = 0.03, 95% confidence interval = 0.47, 0.97). The opposite was found with aspirin and that for diabetic individuals that use insulin. A secondary analysis discovered a significant interaction between aspirin use and insulin: aspirin was associated with lower rates of lung disease except among those taking both drugs where the prevalence is significantly higher. Conclusion: These data suggest a negative correlation between the use of aspirin and obstructive lung disease prevalence in patients with diabetes but not for those that use insulin. Further studies are required to determine if this association is causal.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"38 1","pages":"5 - 10"},"PeriodicalIF":0.0,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76601637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential enhanced association between obstructive lung disease and history of depression in patients with diabetes","authors":"M. Ramos-Nino, Charles D MacLean, B. Littenberg","doi":"10.46439/pulmonology.1.001","DOIUrl":"https://doi.org/10.46439/pulmonology.1.001","url":null,"abstract":"Background: Depression is one of the most common comorbidities of chronic diseases including diabetes and obstructive lung diseases (emphysema, chronic bronchitis, and asthma). Obstructive lung diseases and depression have few symptoms in common. However, they are both common in adults and associated with chronic inflammation. It is not clear if their coappearance in diabetic patients is coincidental or associated beyond that expected by chance. Methods: A total of 1,003 adults with diabetes in community practice settings were interviewed at home at the time of their enrolment into the Vermont Diabetes Information System, a clinical decision support program. Patients self-reported their personal and clinical characteristics, including any obstructive lung disease. Laboratory data were obtained directly from the clinical laboratory, and current medications were obtained by direct observation of medication containers. We performed a cross-sectional analysis of the interviewed subjects to assess a possible association between the prevalence of obstructive lung disease and depression. Results: In a multivariate logistic regression model, obstructive lung disease was significantly associated with depression even after correcting for gender, obesity (≥30 kg/m2), high comorbidities (>2), low annual income (<$30,000/ year), cigarette smoking, alcohol problems, and education level (odds ratio=1.83; 95% confidence interval 1.27, 2.62; P <0.01). Conclusion: These data suggest a potential enhanced association between obstructive lung disease and depression in patients with diabetes. Future studies are needed to identify if inflammation is implicated in this association as a common denominator.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"95 1","pages":"1 - 4"},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75126142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria E Ramos-Nino, Charles D MacLean, Benjamin Littenberg
{"title":"Association between the prevalence of obstructive lung disease and the use of aspirin in a diabetic population.","authors":"Maria E Ramos-Nino, Charles D MacLean, Benjamin Littenberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Many diabetic patients take a daily low-dose of aspirin because they are two to three times more likely to suffer from heart attacks and strokes, but its role in obstructive lung diseases is less clear.</p><p><strong>Methods: </strong>A total of 1,003 subjects in community practice settings were interviewed at home. Patients self-reported their personal and clinical characteristics, including any history of obstructive lung disease (including COPD or asthma). Current medications were obtained by the direct observation of medication containers. We performed a cross-sectional analysis of the interviewed subjects to assess for a possible association between obstructive lung disease history and the use of aspirin.</p><p><strong>Results: </strong>In a multivariate logistic regression model, a history of obstructive lung disease was significantly associated with the use of aspirin even after correcting for potential confounders, including gender, low income (<USD 30,000/year), number of comorbidities, number of medications, cigarette smoking, and alcohol problems (adjusted odds ratio = 0.67, <i>P</i> = 0.03, 95% confidence interval = 0.47, 0.97). The opposite was found with aspirin and that for diabetic individuals that use insulin. A secondary analysis discovered a significant interaction between aspirin use and insulin: aspirin was associated with lower rates of lung disease except among those taking both drugs where the prevalence is significantly higher.</p><p><strong>Conclusion: </strong>These data suggest a negative correlation between the use of aspirin and obstructive lung disease prevalence in patients with diabetes but not for those that use insulin. Further studies are required to determine if this association is causal.</p>","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"1 1","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margarida Silva, S. Neves, S. Campainha, D. Coutinho, J. Almeida, Ana Oliveira
{"title":"Rapid on-site cytological evaluation during endobronchial ultrasound guided transbronchial fine needle aspiration","authors":"Margarida Silva, S. Neves, S. Campainha, D. Coutinho, J. Almeida, Ana Oliveira","doi":"10.1183/13993003.congress-2021.pa2455","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa2455","url":null,"abstract":"","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75418825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Catarina Gouveia Cardoso, M. Serino, D. BARROS COELHO, S. Guimarães, C. Souto Moura, P. Caetano Mota, N. Melo, J. Pereira, R. Cunha, André Carvalho, A. Morais, Hélder Novais-Bastos
{"title":"Predictors of pneumothorax after transbronchial lung cryobiopsy for diagnosis of interstitial lung diseases","authors":"Ana Catarina Gouveia Cardoso, M. Serino, D. BARROS COELHO, S. Guimarães, C. Souto Moura, P. Caetano Mota, N. Melo, J. Pereira, R. Cunha, André Carvalho, A. Morais, Hélder Novais-Bastos","doi":"10.1183/13993003.congress-2021.pa852","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa852","url":null,"abstract":"","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79833266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sundaralingam, R. Banka, Nicky Russel, E. Bedawi, N. Kanellakis, Ellayeh Mohamed, V. George, D. Addala, R. Hallifax, J. Wrightson, N. Rahman
{"title":"Comparison of Direct vs Indirect Thoracic Ultrasound (TUS) guidance for pleural procedures and effects on pain scores","authors":"A. Sundaralingam, R. Banka, Nicky Russel, E. Bedawi, N. Kanellakis, Ellayeh Mohamed, V. George, D. Addala, R. Hallifax, J. Wrightson, N. Rahman","doi":"10.1183/13993003.congress-2021.pa3787","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3787","url":null,"abstract":"","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"110 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91432710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kapetanakis, A. Kostroglou, P. Matsota, I. Tomos, P. Tomos, T. Sidiropoulou
{"title":"Monitored Anesthesia Care with Dexmedetomidine in Patients Undergoing Pleuroscopy: Effect on Oxygenation and Respiratory Function. A Prospective, Single-center Study","authors":"E. Kapetanakis, A. Kostroglou, P. Matsota, I. Tomos, P. Tomos, T. Sidiropoulou","doi":"10.1183/13993003.congress-2021.pa3790","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3790","url":null,"abstract":"","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83541671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kontogianni, J. Brock, F. Trudzinski, C. Heussel, F. Herth, R. Eberhardt
{"title":"Evaluation of the Lung Volume Reduction Reverser System (LVR-R) in treating patients with severe emphysema. Feasibility and safety at 6 months follow up; preliminary results","authors":"K. Kontogianni, J. Brock, F. Trudzinski, C. Heussel, F. Herth, R. Eberhardt","doi":"10.1183/13993003.congress-2021.pa3799","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3799","url":null,"abstract":"","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89985309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}