Interventional pulmonology (Middletown, Del.)最新文献_第9页

Targeted Lung Denervation modulates the bronchial epithelial transcriptome in COPD 靶向肺去神经支配调节COPD支气管上皮转录组

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa5169

K. Srikanthan, L. Kistemaker, D. Slebos, W. Gesierich, K. Darwiche, P. Bonta, G. Deslée, P. Shah, R. Gosens

引用次数: 1

Transbronchial cryobiopsy in the multidisciplinary diagnosis of pneumoconiosis 经支气管冷冻活检在尘肺病多学科诊断中的应用

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3106

Shuliang Guo, Z. Ao, Wanling Zeng, Yishi Li, S. Jin, Xianghua Yi, Xuyou Zhu, Jinyue Jiang, Yang Xiao, Xingxing Jin

引用次数: 1

Mechanisms of action of endobronchial coil treatment 支气管内线圈治疗的作用机制

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3154

J. Hartman, K. Klooster, Sonja W. S. Augustijn, W. H. V. Geffen, J. Garner, P. Shah, N. T. Hacken, D. Slebos

引用次数: 0

Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases 肺间质性疾病患者获得高质量支气管肺泡灌洗的预测变量

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa4790

P. Ortega, A. Papadopoulos, Julie M Martin, Christopher Craig, Andrew Cheng, C. Hayton, C. Leonard, N. Chaudhuri, A. Montero

{"title":"Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases","authors":"P. Ortega, A. Papadopoulos, Julie M Martin, Christopher Craig, Andrew Cheng, C. Hayton, C. Leonard, N. Chaudhuri, A. Montero","doi":"10.1183/13993003.congress-2019.pa4790","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4790","url":null,"abstract":"Introduction: Bronchoalveolar lavage (BAL) is a well-recognised diagnostic tool in patients with Interstitial Lung Disease (ILD). According to the guidelines published by the American Thoracic Society/European Respiratory Society, a BAL is considered of adequate quality when percentage of other cells (epithelial/columnar cells) is Objectives: Determine the predictive variables for obtaining BAL of adequate quality in ILD patients. Methods: Retrospective study of all BALs performed from August 2018 to January 2019 on a dedicated ILD bronchoscopy list of a thoracic referral centre in the United Kingdom. Demographic, clinical, computed tomography (CT) pattern, procedure technique and histopathological data were collected. Results: 63 BALs were performed (27 women and 36 men, mean age of 63 years-old). We obtained adequate BAL quality in 19 patients (30%). Table 1 shows all the variables evaluated according to the quality of BAL. The absence of smoking history and the CT pattern of indeterminate for usual interstitial pneumonia were independent variables associated with an adequate BAL quality (p-value of 0.05 and 0.02, respectively). Conclusion: Smoking history and CT pattern could influence the BAL quality, regardless of lung function and procedure technique.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80798772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early and late complications of lung volume reduction coil therapies 肺减容线圈治疗的早期和晚期并发症

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3152

A. Gülşen, A. Girgin

{"title":"Early and late complications of lung volume reduction coil therapies","authors":"A. Gülşen, A. Girgin","doi":"10.1183/13993003.congress-2019.pa3152","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa3152","url":null,"abstract":"Introduction: Bronchoscopic lung volume reduction coil (LVRC) therapy is a non-invasive procedure with potential complications in the early and late follow-up period. Aims and Objectives: The main objective of this study is to determine the incidence of complications in LVRC therapies (during the procedure, and follow-up), and to discuss treatment options. Methods: Forty-five patients who underwent bilateral LVRC treatment for severe emphysema between 2013 and 2015 were included in the study. We retrospectively evaluated the files of all patients, and the study was done in a single pneumology center in Turkey. Results: The most common observed complications during the procedure were mild bleeding (24.4%). Pneumothorax was seen (2.3%) in one patient. The procedure was postponed in 2 patients (4.4%) due to hemodynamic changes during the procedure. In general, the most common complication was COPD exacerbation (26.6%) and procedure related pneumonitis or pneumonia (13.3%) in the follow-up period. Conclusions: Preventive therapies are routinely performed after the procedure, but a common consensus is needed to define risk factors, prevent and manage the complications. In addition, we think that it would be more beneficial to use the percentages as per procedures or per patients in the identification of complications.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80353556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchoscopic lung volume reduction: do sequential endobronchial valve placements reduce pneumothorax rate? 支气管镜下肺减容:序贯支气管内瓣膜置放能降低气胸率吗?

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3153

T. Born, C. Mallinckrodt, P. Grandjean, N. Tekeli

引用次数: 2

Clinical outcomes and micro-costing of bronchial thermoplasty in severe asthma in the UK 英国严重哮喘支气管热成形术的临床结果和微观成本

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa4802

L. White, A. Mansur, C. Capobianco

{"title":"Clinical outcomes and micro-costing of bronchial thermoplasty in severe asthma in the UK","authors":"L. White, A. Mansur, C. Capobianco","doi":"10.1183/13993003.congress-2019.pa4802","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4802","url":null,"abstract":"Bronchial thermoplasty (BT) is a cost-effective (Zafari Z et al. PLoS One. 2016, 11:1) therapy for severe asthma (SA) delivered in three bronchoscopic procedures. National Institute for Health and Care Excellence recently recognized the safety and efficacy of BT for SA treatment (NICE IPG635,2018). Aim: Measure patient outcomes pre and post BT treatment and compare the actual cost of BT to national reference costs and tariff income to assess the adequacy of current payment in the UK. Methods: We performed a retrospective micro costing study on 53 BT procedures (total of 18 patients) over the 2012-2017 period at a UK hospital. We collected patient outcomes 12 months before and after BT. For comparison we used 2017/18 national reference costs and national tariffs of the HRG DZ67Z Major Therapeutic Bronchoscopy. Results: After BT, we observed a significant improvement in mean FEV1(1.99L ± 0.64 vs 2.50L ± 0.66; p=0.001), and a reduction of mean rescue oral corticosteroid/year (6.6 ± 4.2 vs 1.5 ± 1.7; p=0.00004). The average cost of a BT session was £3362 for day cases (DC) performed under sedation (n=22), £4354 for elective admissions (EL) under sedation (n=27), £6925 for EL under general anesthesia (n=4). This compares to 2017/18 reference costs for DC and EL of £1380 and £2563 respectively, demonstrating an average deficit of £2064. 2017/18 tariff for DC and EL of £2050 does not cover BT admission costs whether BT is done as a DC or EL. Conclusions: In this patient group BT improved health outcomes. Micro costing reveals that reference costs do not reflect the actual cost of BT. Since reimbursement is based on reference costs, BT is underfunded, which may represent a barrier to patient access.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75871372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endobronchial Ultrasound Transbronchial Needle Aspiration (EBUS-TBNA) versus Flexible 19G Endobronchial Ultrasound Transbronchial Needle (Flex 19G EBUS-TBNA) in the Assessment of Mediastinal and Hilar Lymphadenopathy: a Randomised Trial 支气管超声经支气管针抽吸(EBUS-TBNA)与柔性19G支气管超声经支气管针(Flex 19G EBUS-TBNA)评估纵隔和肺门淋巴结病的随机试验

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa324

E. Tenda, A. Aboelhassan, K. Kontogianni, A. Rice, S. Crichton, J. Garner, K. Srikanthan, A. Nicholson, A. Harms, F. Herth, S. Kemp, R. Eberhardt, P. Shah

引用次数: 5

Added value of cone beam CT imaging to electromagnetic navigation bronchoscopy in diagnosing small pulmonary lesions 锥形束CT成像对电磁导航支气管镜诊断肺部小病变的价值

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3116

R. Verhoeven, J. Fütterer, W. Hoefsloot, E. V. D. Heijden

引用次数: 2

First in human experience of placement of a new size endobronchial valve 5.5LP 在人类经验中首次置入新尺寸的5.5LP支气管内瓣膜

Interventional pulmonology (Middletown, Del.) Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa3150

K. Klooster, D. Koster, M. V. Dijk, J. Hartman, E. V. Rikxoort, D. Slebos

{"title":"First in human experience of placement of a new size endobronchial valve 5.5LP","authors":"K. Klooster, D. Koster, M. V. Dijk, J. Hartman, E. V. Rikxoort, D. Slebos","doi":"10.1183/13993003.congress-2019.pa3150","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa3150","url":null,"abstract":"Introduction: Bronchoscopic Lung Volume Reduction using Zephyr® EBV is a guideline treatment for patients with advanced emphysema. To achieve volume reduction it is crucial that there is absence of collateral ventilation and a full occlusion of the target lobe. While 3 EBV sizes (4.0;4.0LP;5.5) are currently available to accommodate all airway sizes, local anatomical variations sometimes warrant a wide but shorter valve. To address this, a new ‘low profile’ 5.5LP EBV has been introduced. Aim: We evaluated feasibility, safety and efficacy of this 5.5LP EBV. Method: This was a single center, prospective open label study. Patients were included if eligible for valve treatment with a local anatomy suitable to place at least one EBV5.5LP to achieve complete lobar occlusion. Feasibility of placement of the EBV5.5LP was reported. Safety, CT and PFT were assessed at baseline and 45day post treatment. Results: Fourteen patients (FEV1 27±10%;RV 254±39%) were included. Besides the regular EBV sizes, the 5.5LP EBV were placed into the segments: RB(2), RB6(3), RB9/10(1), LB3(1),LB6(7),LB8-10(3). No valve adjustment was needed, no dislocation occurred up to 45 day post treatment. One asymptomatic small pneumothorax was observed. See figure for procedure and efficacy. Conclusion: In this first in human study the 5.5LP EBV was feasible and could be placed into wide segments with a shorter landing space without complications and with good efficacy outcomes.","PeriodicalId":93455,"journal":{"name":"Interventional pulmonology (Middletown, Del.)","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76016968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0