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Online journal of neurology and brain disorders最新文献

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Neurological, neuropsychiatric and psychiatric symptoms during COVID-19 infection and after recovery: a systematic review of observational studies 新冠肺炎感染期间和康复后的神经、神经精神和精神症状：观察性研究的系统综述
Online journal of neurology and brain disorders Pub Date : 2021-07-07 DOI: 10.1101/2021.07.02.21259902
M. Stavrou, S. Solomou, A. Kythreotou, A. Ioannou, Eva Lioutas, Joanna Lioutas, P. Karayiannis
{"title":"Neurological, neuropsychiatric and psychiatric symptoms during COVID-19 infection and after recovery: a systematic review of observational studies","authors":"M. Stavrou, S. Solomou, A. Kythreotou, A. Ioannou, Eva Lioutas, Joanna Lioutas, P. Karayiannis","doi":"10.1101/2021.07.02.21259902","DOIUrl":"https://doi.org/10.1101/2021.07.02.21259902","url":null,"abstract":"Background The SARS-CoV-2 virus causes a wide spectrum of disease severity. Initial manifestations include fever, dry cough, and constitutional symptoms, which may progress to respiratory disease. There may also be neurological and psychiatric manifestations, involving both the central and peripheral nervous system. Methods We performed a literature search of the databases PubMed, EMBASE, The Cochrane Library and Web of Science for observational studies reporting neurological, psychiatric, and neuropsychiatric effects of COVID-19. This was followed by a narrative synthesis to summarise the data and discuss neuropsychiatric associations, symptom severity, management, and recovery. Findings The most frequently reported neurological symptoms were ageusia, hyposmia/anosmia, dizziness, headache, and loss of consciousness. Statistically significant relationships were noted between Asian ethnicity and peripheral neuropathy (p=0.0001) and neuro-syndromic symptoms (p=0.001). ITU admission was found to have a statistically significant relationship with male sex (p=0.024). Depression and anxiety were also identified both during and after infection. The most frequent treatments used were intravenous immunoglobulins, followed by antibiotics, antivirals, and hydroxychloroquine; with mean treatment duration of 6 days. Interpretation Various neuropsychiatric symptoms have been associated with COVID-19 infection. More studies are required to further our knowledge in the management of neurological and psychiatric symptoms during and after COVID-19 infection","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44686705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibrinogen and/or Fibrin as a Cause of Neuroinflammation. 纤维蛋白原和/或纤维蛋白作为神经炎症的原因。
Online journal of neurology and brain disorders Pub Date : 2021-04-14 DOI: 10.32474/OJNBD.2021.05.000217
N. Sulimai, D. Lominadze
{"title":"Fibrinogen and/or Fibrin as a Cause of Neuroinflammation.","authors":"N. Sulimai, D. Lominadze","doi":"10.32474/OJNBD.2021.05.000217","DOIUrl":"https://doi.org/10.32474/OJNBD.2021.05.000217","url":null,"abstract":"Involvement of Fibrinogen(Fg) and fibrin during various pathologies associated with neuroinflammatory diseases associated with memory reduction are well known. Elevated level of Fg, called hyperfibrinogenemia (HFg) (e.g. ≥ 4±0.1 mg/ml of plasma during inflammation vs.~2±0.1 mg/ml of normal plasma [1]), accompanies inflammatory diseases such as stroke [2,3], hypertension [1,4], diabetes [5] and Traumatic Brain Injury (TBI) [6-9]. Blood level of Fg increases during inflammation in general [10].","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47430678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Electrophysiological Findings in Neuromyelitis Optica Spectrum Disorder 视谱障碍神经脊髓炎的电生理表现
Online journal of neurology and brain disorders Pub Date : 2021-01-25 DOI: 10.32474/OJNBD.2021.05.000203
K. Ohnari, Hiroaki Adachi
{"title":"Electrophysiological Findings in Neuromyelitis Optica Spectrum Disorder","authors":"K. Ohnari, Hiroaki Adachi","doi":"10.32474/OJNBD.2021.05.000203","DOIUrl":"https://doi.org/10.32474/OJNBD.2021.05.000203","url":null,"abstract":"Neuromyelitis Optica Spectrum Disorder (NMOSD) is an\u0000autoimmune, inflammatory, necrotic disease with lesions...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45318446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibrinogen and/or Fibrin as a Cause of Neuroinflammation. 纤维蛋白原和/或纤维蛋白作为神经炎症的原因。
Online journal of neurology and brain disorders Pub Date : 2021-01-01 Epub Date: 2021-04-14
Nurul Sulimai, David Lominadze
{"title":"Fibrinogen and/or Fibrin as a Cause of Neuroinflammation.","authors":"Nurul Sulimai, David Lominadze","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318361/pdf/nihms-1707287.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39259102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding PTSD and Depression During the Pandemic Watch 在流行病观察期间了解创伤后应激障碍和抑郁症
Online journal of neurology and brain disorders Pub Date : 2020-11-30 DOI: 10.32474/ojnbd.2020.04.000199
Kristi L. Kanel
{"title":"Understanding PTSD and Depression During the Pandemic Watch","authors":"Kristi L. Kanel","doi":"10.32474/ojnbd.2020.04.000199","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000199","url":null,"abstract":"Since the world became familiar with the Pandemic related to\u0000the Novel Corona Virus, or COVID 19, most people have experienced...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42268030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cranio-Cervical Junction Meningioma: A Rare Case Report 颅颈交界处脑膜瘤1例报告
Online journal of neurology and brain disorders Pub Date : 2020-11-06 DOI: 10.32474/ojnbd.2020.04.000198
Sukriti Das, A. Sarker, D. Ghosh, Kanji Fatema Ishrat Zahan, M. S. Khan, A. Khan, B. Chaurasia
{"title":"Cranio-Cervical Junction Meningioma: A Rare Case Report","authors":"Sukriti Das, A. Sarker, D. Ghosh, Kanji Fatema Ishrat Zahan, M. S. Khan, A. Khan, B. Chaurasia","doi":"10.32474/ojnbd.2020.04.000198","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000198","url":null,"abstract":"Meningiomas were named by Harvey Cushing in 1922 and\u0000described as common tumors that arise from arachnoid cap cells...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47686244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Co-Occurrence of High Degree Atrioventricular Block and Facial Pain in Lateral Medullary Stroke 脊髓侧卒中并发高度房室传导阻滞和面部疼痛
Online journal of neurology and brain disorders Pub Date : 2020-10-09 DOI: 10.32474/ojnbd.2020.04.000195
Shairin Sihabdeen, C. Cereda, C. Staedler, G. Chiaro, E. Ventura, M. Manconi
{"title":"Co-Occurrence of High Degree Atrioventricular Block and Facial Pain in Lateral Medullary Stroke","authors":"Shairin Sihabdeen, C. Cereda, C. Staedler, G. Chiaro, E. Ventura, M. Manconi","doi":"10.32474/ojnbd.2020.04.000195","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000195","url":null,"abstract":"Wallenberg syndrome is the most frequent clinical\u0000manifestation of brainstem ischemia, and it is due to lateral...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45537504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhinal Cortices Connecting the Papez and Yakovlev Circuits: An Integrated Viewpoint Through MRI Epidemiology to Animal Experiment for Better Understanding Clinical Features of Alzheimer Disease and Vascular Dementia 连接Papez和Yakovlev回路的鼻皮质:从MRI流行病学到动物实验的综合观点，以更好地了解阿尔茨海默病和血管性痴呆的临床特征
Online journal of neurology and brain disorders Pub Date : 2020-10-07 DOI: 10.32474/ojnbd.2020.04.000193
K. Meguro
{"title":"Rhinal Cortices Connecting the Papez and Yakovlev Circuits: An Integrated Viewpoint Through MRI Epidemiology to Animal Experiment for Better Understanding Clinical Features of Alzheimer Disease and Vascular Dementia","authors":"K. Meguro","doi":"10.32474/ojnbd.2020.04.000193","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000193","url":null,"abstract":"I herein present a unique statement, not focusing on the specific area but present an integrated viewpoint through...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41931431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Potential of TRPM Modulator TRPM调节剂的治疗潜力
Online journal of neurology and brain disorders Pub Date : 2020-10-06 DOI: 10.32474/ojnbd.2020.04.000192
Anil Kumar, N. Rawat, Hemprabha Tainguriya
{"title":"Therapeutic Potential of TRPM Modulator","authors":"Anil Kumar, N. Rawat, Hemprabha Tainguriya","doi":"10.32474/ojnbd.2020.04.000192","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000192","url":null,"abstract":"Transient Receptor Potential (TRP) channels are group of\u0000membrane proteins that play a key role in managing variety...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46226264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synaptopathies, Neurotransmitters and Pharmacological Management of Epilepsy and Neurodevelopmental Disorders 突触病变，神经递质和癫痫和神经发育障碍的药理学管理
Online journal of neurology and brain disorders Pub Date : 2020-10-01 DOI: 10.32474/ojnbd.2020.04.000191
J. Pisón, M. Andrés
{"title":"Synaptopathies, Neurotransmitters and Pharmacological Management of Epilepsy and Neurodevelopmental Disorders","authors":"J. Pisón, M. Andrés","doi":"10.32474/ojnbd.2020.04.000191","DOIUrl":"https://doi.org/10.32474/ojnbd.2020.04.000191","url":null,"abstract":"We pediatric neurologists treat many children with neurodevelopmental disorders and/or epilepsy...","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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