{"title":"纤维蛋白原和/或纤维蛋白作为神经炎症的原因。","authors":"N. Sulimai, D. Lominadze","doi":"10.32474/OJNBD.2021.05.000217","DOIUrl":null,"url":null,"abstract":"Involvement of Fibrinogen(Fg) and fibrin during various pathologies associated with neuroinflammatory diseases associated with memory reduction are well known. Elevated level of Fg, called hyperfibrinogenemia (HFg) (e.g. ≥ 4±0.1 mg/ml of plasma during inflammation vs.~2±0.1 mg/ml of normal plasma [1]), accompanies inflammatory diseases such as stroke [2,3], hypertension [1,4], diabetes [5] and Traumatic Brain Injury (TBI) [6-9]. Blood level of Fg increases during inflammation in general [10].","PeriodicalId":93346,"journal":{"name":"Online journal of neurology and brain disorders","volume":"5 4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Fibrinogen and/or Fibrin as a Cause of Neuroinflammation.\",\"authors\":\"N. Sulimai, D. Lominadze\",\"doi\":\"10.32474/OJNBD.2021.05.000217\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Involvement of Fibrinogen(Fg) and fibrin during various pathologies associated with neuroinflammatory diseases associated with memory reduction are well known. Elevated level of Fg, called hyperfibrinogenemia (HFg) (e.g. ≥ 4±0.1 mg/ml of plasma during inflammation vs.~2±0.1 mg/ml of normal plasma [1]), accompanies inflammatory diseases such as stroke [2,3], hypertension [1,4], diabetes [5] and Traumatic Brain Injury (TBI) [6-9]. Blood level of Fg increases during inflammation in general [10].\",\"PeriodicalId\":93346,\"journal\":{\"name\":\"Online journal of neurology and brain disorders\",\"volume\":\"5 4 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-04-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Online journal of neurology and brain disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32474/OJNBD.2021.05.000217\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Online journal of neurology and brain disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32474/OJNBD.2021.05.000217","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fibrinogen and/or Fibrin as a Cause of Neuroinflammation.
Involvement of Fibrinogen(Fg) and fibrin during various pathologies associated with neuroinflammatory diseases associated with memory reduction are well known. Elevated level of Fg, called hyperfibrinogenemia (HFg) (e.g. ≥ 4±0.1 mg/ml of plasma during inflammation vs.~2±0.1 mg/ml of normal plasma [1]), accompanies inflammatory diseases such as stroke [2,3], hypertension [1,4], diabetes [5] and Traumatic Brain Injury (TBI) [6-9]. Blood level of Fg increases during inflammation in general [10].
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