Bulletin of emergency and trauma最新文献_第9页

The Outcome Predictors of the Patients with Traumatic Brain Injury; A Cross-Sectional Study. 外伤性脑损伤患者预后的预测因素横断面研究。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2022.95587.1364

Soheil Rafiee, Alireza Baratloo, Arash Safaie, Alireza Jalali, Khalil Komlakh

{"title":"The Outcome Predictors of the Patients with Traumatic Brain Injury; A Cross-Sectional Study.","authors":"Soheil Rafiee, Alireza Baratloo, Arash Safaie, Alireza Jalali, Khalil Komlakh","doi":"10.30476/BEAT.2022.95587.1364","DOIUrl":"https://doi.org/10.30476/BEAT.2022.95587.1364","url":null,"abstract":"Objective: To probe the factors associated with the outcomes of traumatic brain injury (TBI) patients admitted to emergency department (ED).Methods: This is a cross-sectional study that data gathering was performed via census methods, retrospectively. During one year, all head injury's patients who admitted to the ED of a tertiary center in Tehran, Iran were included. Age, gender, mechanism of injury, Glasgow coma scale (GCS) and injury severity score (ISS) on admission, presence of extra-cranial injuries, findings of brain computed tomography (CT), duration of hospitalization, and in hospital outcomes were recorded. Outcome's assessment for survivors was performed within a 6 months-period after discharge based on Glasgow outcome scale (GOS). The variables and outcomes' association were assessed.Results: Totally, 506 patients were evaluated with the mean age of 36.77±21.1 years that 411 (81.2%) were men. Follow up at 6-months post injury was feasible in 487 (96.2%) patients; 59 (11.7%) out of 506 eligible patients died. Logistic regression analysis showed the association between assessed variables and patients' outcome as follows: age>65 years (OR: 12.21; p<0.001), GCS on admission <8 (OR: 62.99; p<0.001), presence of traumatic Intracerebral hemorrhage (ICH) in brain CT scan (OR: 20.11; p=0.010), duration of hospitalization ≥ 5 days (OR: 0.28; p=0.001).Conclusion: The findings of the current study distinguished some variables that were associated with the poor outcome of the patients with TBI. Therefore, TBI patients with any of these risk factors may need close continues monitoring, early ICU admission, and some other special extra care in ED.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 4","pages":"165-171"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/38/bet-10-165.PMC9758707.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10803478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Influencing the Use of Pedestrian Bridges in North of Iran. 影响伊朗北部人行天桥使用的因素。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2022.92068.1297

Zahra Mohtasham-Amiri, Iraj Barge-Gol, Leila Kouchakinejad-Eramsadati, Payam Abedian, Helya Jafari-Shakib

{"title":"Factors Influencing the Use of Pedestrian Bridges in North of Iran.","authors":"Zahra Mohtasham-Amiri, Iraj Barge-Gol, Leila Kouchakinejad-Eramsadati, Payam Abedian, Helya Jafari-Shakib","doi":"10.30476/BEAT.2022.92068.1297","DOIUrl":"https://doi.org/10.30476/BEAT.2022.92068.1297","url":null,"abstract":"Objective: To find out factors that influence the use/non-use of pedestrian bridges in Northern Iran.Methods: In this observational study, 4 pedestrian bridges at four different places in Rasht, North of Iran was studied. In addition to demographic data, pedestrians were interviewed for reasons of use/not use the pedestrian bridge. The data analyzed with SPSS software version 18 by non-parametric tests such as Chi Square.Results: From all 499 participants, more than one-third of pedestrians had not used pedestrian bridges. The most reasons for bridges use among respondents were feeling of safety and security (79.2%) and obey the rules (53.6%). The reasons for the non-use of bridges were time saving (63.7%), laziness (48.7%) and inappropriate of the bridge (34.2%). There were no significant differences in age, sex, education level, and road accidents' history with use of bridge but there was a significant difference between the bridge usage with having a driver's license, rash-hour time, and the presence of a mechanical elevator (p<0.001).Conclusion: The results of this study show that in order to increase the pedestrian bridges use, it is necessary to pay more attention to make standard facilities such as installing escalators or elevators of these bridges.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39915462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Association of Serum Biomarkers with the Mortality of Trauma Victims in a Level -1 Trauma Care Centre of Eastern India. 血清生物标志物与印度东部一级创伤护理中心创伤受害者死亡率的关系。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2022.89155.1222

Kasturi Mukherjee, Debojyoti Bhattacharjee, Jayati Roy Choudhury, Raghunath Bhattacharyya

{"title":"Association of Serum Biomarkers with the Mortality of Trauma Victims in a Level -1 Trauma Care Centre of Eastern India.","authors":"Kasturi Mukherjee, Debojyoti Bhattacharjee, Jayati Roy Choudhury, Raghunath Bhattacharyya","doi":"10.30476/BEAT.2022.89155.1222","DOIUrl":"https://doi.org/10.30476/BEAT.2022.89155.1222","url":null,"abstract":"Objective: To determine correlation of important biochemical laboratory investigations in different trauma patients and their degree of injury severity and overall mortality association.Methods: In this hospital based retrospective observational study, 238 trauma patients were divided into two groups. Group I with injury severity score (ISS)<16 and group II with ISS>16. Haemoglobin (Hb), international normalized ratio, serum creatinine, blood urea nitogen (BUN), serum electrolyte, serum uric acid and liver function parameters were recorded and statistically analyzed.Results: Group II had statistically significant (p<0.0001) elevated levels for referral pulse rate, creatinine, BUN, liver enzymes and decreased level in Hb% and potassium level compared to Group I. Strong positive correlation only exists between BUN and severity score, moderate positive correlation exists between creatinine, aspartate transaminase, and alanine transaminase, alkaline phosphatase and severity score and negative correlation between potassium and severity score. In this study, higher odds of high BUN and creatinine and lower potassium to normal values are associated with bad outcome such as higher mortality in the population of high ISS (>16).Conclusion: The study establishes the absolute need of doing three laboratory parameters (serum creatinine, serum blood urea nitrogen and serum potassium) instead of doing laboratory tests battery at the time of trauma victims admission and predicting survival among injured patients in trauma population from Indian settings.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 1","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39915463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Years of Life Lost (YLLs) Due to Suicide and Homicide in Ilam Province: Iran, 2014-2018. 2014-2018年伊朗伊拉姆省因自杀和凶杀而损失的生命年数。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2022.92045.1293

Yousef Veisani, Amin Bakhtiyari, Fathola Mohamadian

{"title":"Years of Life Lost (YLLs) Due to Suicide and Homicide in Ilam Province: Iran, 2014-2018.","authors":"Yousef Veisani, Amin Bakhtiyari, Fathola Mohamadian","doi":"10.30476/BEAT.2022.92045.1293","DOIUrl":"https://doi.org/10.30476/BEAT.2022.92045.1293","url":null,"abstract":"Objective: To provide detailed of suicide and homicide mortality and calculate of years of life lost (YLLs) in Ilam province Iran, during 2014-2018.Methods: In this cross-sectional study, all deaths due to suicide and homicide were enrolled to estimate YLLs, in Ilam province between 2014-2018. The source of data was legal medicine organization (LMO). All analysis was performed at 0.05 significant levels using statistical software package STATA for Windows version 11.2 and SPSS 21 software.Results: The total YLLs of suicide and homicide were 15685 and 5317, respectively. 522 per 100,000 populations were suicide and 117 for homicide. The YLL and 95% confidence interval form suicide was 34.4 (32.8-36.1) for both sexes that 33.7 (31.6-35.8) for men, and 35.5 (32.7-38.3) for women. In this study period, YLLs rate began to increase over the years in both injury-related in 2016.Conclusion: Results of this study disclosed the most prominent contribution of men and peoples aged 15-29 to the YLLs. Also our results indicate a recent increase in suicide and homicide YLLs for both genders.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 1","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39915460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Prevalence of Pediatric Ocular Trauma in Northern Iran; An Epidemiological Cross-Sectional Study. 伊朗北部儿童眼外伤患病率流行病学横断面研究。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2021.90773.1262

Hanieh Ahmadi, Zahra Alizadeh, Samad Karkhah, Mohammad Javad Ghazanfari

{"title":"Prevalence of Pediatric Ocular Trauma in Northern Iran; An Epidemiological Cross-Sectional Study.","authors":"Hanieh Ahmadi, Zahra Alizadeh, Samad Karkhah, Mohammad Javad Ghazanfari","doi":"10.30476/BEAT.2021.90773.1262","DOIUrl":"https://doi.org/10.30476/BEAT.2021.90773.1262","url":null,"abstract":"Ocular trauma is one of the most common causes of acquired blindness in children. The epidemiological parameters associated with ocular trauma vary in different populations, especially in children. The objective of this study was to assess the ocular trauma epidemiology in children less than 18 years of age. In this cross-sectional study, 145 children (under 18 years) with ocular trauma who referred to the emergency department of Bu-Ali-Sina Hospital in Sari, Iran were enrolled from November 2017 to January 2019. Of the participants, 57.9% were men, 70.4% had blunt trauma, 97.2% had a unilateral eye injury, and 54.5% had a right eye injury. The most risk factor for trauma was stationery (51.0%). Almost half of the patients (52.9%) had corneal injuries. The most trauma locations were at home (67.4%). Most patients (95.0%) had normal relative afferent pupillary defects. Blunt (52.6% vs. 47.4%) and penetrating (72.5% vs. 27.5%) traumas was higher in boys than girls (p=0.03). Most frequent part of eye injuries in blunt and penetrating traumas was related to the cornea (P=0.04). It seems that parents should have more supervision on children at home and give adequate education in using of stationery to school-age children by considering the results of present study.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 1","pages":"40-43"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39915464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Severe Acute Kidney Injury Secondary to Immunoglobulin Infusion in Life-Threatening Guillain Barre Syndrome. 严重急性肾损伤继发免疫球蛋白输注危及生命的格林-巴利综合征。

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2021.85702.1103

José David Orquera, María Marta Pernasetti, Patricia Ojeda, Griselda Agüero, Daniel Agustín Godoy

{"title":"Severe Acute Kidney Injury Secondary to Immunoglobulin Infusion in Life-Threatening Guillain Barre Syndrome.","authors":"José David Orquera, María Marta Pernasetti, Patricia Ojeda, Griselda Agüero, Daniel Agustín Godoy","doi":"10.30476/BEAT.2021.85702.1103","DOIUrl":"https://doi.org/10.30476/BEAT.2021.85702.1103","url":null,"abstract":"Immunoglobulin infusion (IVIG) is one of the first line therapy in Guillain Barre Syndrome (GBS). Several medical complications are associated with GBS (pneumonia, sepsis, deep vein thrombosis, dysautonomy). Acute kidney injury (AKI) is an uncommon complication during IVIG infusion. Several risk factors were associated with AKI during IVIG. These are an older age, previous renal disease, concomitant use of nephrotoxic agents, diabetes mellitus, hypovolemia, sepsis or using of IVIG that contained in its preparation sucrose or mannitol as stabilizers to avoid precipitation and aggregation. Infusion rate and total dose play a determinant role. The most important pathophysiological mechanism of AKI are the osmotic stress applied to the epithelium of proximal tubules and glomeruli. The osmotic overload is principally generated by IVIG stabilizers (sucrose). In general, AKI is reversible but approximately 30% hemodialysis is necessary. It is essential to respect doses, infusion rates and closely monitoring renal function parameters during IVIG infusion.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 1","pages":"44-48"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39915465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trauma and COVID-19: Clinical and Paraclinical similarities between Trauma Patients with Positive and Negative PCR Tests. 创伤与 COVID-19：PCR 检测呈阳性和阴性的外伤患者在临床和辅助临床方面的相似性

Bulletin of emergency and trauma Pub Date : 2022-01-01 DOI: 10.30476/BEAT.2022.96357.1387

Golnar Sabetian, Hossein Abdolrahimzadeh Fard, Mina Ostovan, Sina Azadikhah, Farid Zand, Mansoor Masjedi, Naeimehossadat Asmarian

{"title":"Trauma and COVID-19: Clinical and Paraclinical similarities between Trauma Patients with Positive and Negative PCR Tests.","authors":"Golnar Sabetian, Hossein Abdolrahimzadeh Fard, Mina Ostovan, Sina Azadikhah, Farid Zand, Mansoor Masjedi, Naeimehossadat Asmarian","doi":"10.30476/BEAT.2022.96357.1387","DOIUrl":"10.30476/BEAT.2022.96357.1387","url":null,"abstract":"Objective: To compare clinical and paraclinical similarities between trauma patients with positive RT-PCR tests (PCR+ve) and the RT-PCR negative ones (PCR -ve).Methods: This a case-control study, where cases had a PCR+ve and controls had a negative result. Two groups were compared regarding (para) clinical values. Multivariable binary logistic regression analysis investigated the variables predicting COVID-19 and the mortality rate.Results: Both groups were similar regarding the clinical findings and comorbidities (p>0.05). PCR+ve group had lower lymphocyte count (1.41 [1.45] vs. 1.66 [1.61], p=0.030), CPK level (411 [928.75] vs. 778 [1946.5]. p=0.006) and CRP level (17 [42.5] vs. 24 [50.75], p=0.004). However, none of these findings were significant in the multivariable analysis. Finally, PCR+ve group had increased odds of death (OR=2.88; 95% CI=1.22-7.41).Conclusion: Unlike our primary hypothesis, the study failed to mark any significant (para) clinical features guiding us to detect COVID-19 earlier in trauma patients. Moreover, the PCR+ve group is at increased mortality risk. A larger, multicentric prospective study should be designed to address this issue.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"10 4","pages":"172-180"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/84/bet-10-172.PMC9758711.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10785792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prospective Observational Study of Early Tracheostomy Role in Operated Severe Head Injury Patients at A Level 1 Trauma Center. A级创伤中心重型颅脑损伤手术患者早期气管切开术的前瞻性观察研究

Bulletin of emergency and trauma Pub Date : 2021-10-01 DOI: 10.30476/BEAT.2021.86725.1198

Rohit Bharti, Sindhu Sindhu, Ponraj K Sundaram, Ganesh Chauhan

{"title":"Prospective Observational Study of Early Tracheostomy Role in Operated Severe Head Injury Patients at A Level 1 Trauma Center.","authors":"Rohit Bharti, Sindhu Sindhu, Ponraj K Sundaram, Ganesh Chauhan","doi":"10.30476/BEAT.2021.86725.1198","DOIUrl":"https://doi.org/10.30476/BEAT.2021.86725.1198","url":null,"abstract":"Objective: To evaluate the impact of the early tracheostomy on operated patients with severe head injury.Methods: This prospective observational study was conducted at a level 1 trauma center and medical college over one-year period. The study included all surgically managed severe head injury patients without any other life-threatening major injuries. Patients who underwent tracheostomy within 7 days were classified as early tracheostomy.Results: The patient's mean age of this cohort study was 43.4±14.5 years. Motor-vehicle accidents were being the most common cause of severe head injury. Operated patients were undergoing early tracheostomy on an average of 2.9 days. We were observed that the patients spent on a mechanical ventilation on an average 3.67±2.26 days. This was significantly lower than previous four published studies (p<0.05) which had a range of mean 9.8-15.7 days.Conclusion: We have shown that it is possible to decrease mechanical ventilation (MV) time, intensive care unit (ICU) stay and total hospital stay by doing early tracheostomy in operated severe head injury patients.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"9 4","pages":"188-194"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39553547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics and In-Hospital Outcomes of Pediatric Traumatic Spinal Injuries in A Referral Trauma Center. 某转诊创伤中心儿童外伤性脊柱损伤的特点和住院结果

Bulletin of emergency and trauma Pub Date : 2021-10-01 DOI: 10.30476/BEAT.2021.91333.1275

Hamid Rezaee, Ehsan Keykhosravi, Amin Tavallaii

{"title":"Characteristics and In-Hospital Outcomes of Pediatric Traumatic Spinal Injuries in A Referral Trauma Center.","authors":"Hamid Rezaee, Ehsan Keykhosravi, Amin Tavallaii","doi":"10.30476/BEAT.2021.91333.1275","DOIUrl":"https://doi.org/10.30476/BEAT.2021.91333.1275","url":null,"abstract":"Objective: To evaluate the characteristics and in-hospital outcomes of traumatic spinal injuries among children admitted to a local trauma center in Iran. Methods: Patients aged 0-18 years who had been admitted to Shahid Kamyab trauma center for acute traumatic spinal injury (Mashhad, Iran) between 2011 and 2018 were evaluated retrospectively. Various demographic, clinical, radiological, and outcome variables were recorded and analyzed. Results: A total of 127,300 trauma patients were evaluated and amongst them, 61 children had spinal trauma. The mean age was 11.1 and there was no significant sex preponderance (54% males). Most of the injuries were occurred in summer (34.4%) and the most common trauma mechanism was motor vehicle accidents (55.7%) followed by falling (36.1%). Almost all patients (95.1%) had vertebral fractures, which were in the cervical, thoracic, and lumbosacral area in order to decrease incidence. 67.2% of patients were managed non-surgically. The mean hospital stay was 8.9 days and 82.0% of patients had been discharged with normal motor function. Conclusion: Pediatric spinal trauma is less studied entity in the field of traumatology due to the lower prevalence of these injuries in pediatric patients worldwide. But our study shows a higher prevalence of such injuries in the pediatric population. Although controversial, the leading cause of these injuries is motor vehicle accidents. Fortunately, short term in-hospital outcome seems to be good in such injuries.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"9 4","pages":"178-182"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39553544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

S100 Calcium-Binding Protein B and Glial Fibrillary Acidic Protein in Patients with Mild Traumatic Brain Injury. S100钙结合蛋白B和胶质纤维酸性蛋白在轻度颅脑损伤中的作用。

Bulletin of emergency and trauma Pub Date : 2021-10-01 DOI: 10.30476/BEAT.2021.89355.1231

Ali Meshkini, Amir Ghorbani Haghjo, Zahra Hasanpour Segherlou, Masoud Nouri-Vaskeh

{"title":"S100 Calcium-Binding Protein B and Glial Fibrillary Acidic Protein in Patients with Mild Traumatic Brain Injury.","authors":"Ali Meshkini, Amir Ghorbani Haghjo, Zahra Hasanpour Segherlou, Masoud Nouri-Vaskeh","doi":"10.30476/BEAT.2021.89355.1231","DOIUrl":"https://doi.org/10.30476/BEAT.2021.89355.1231","url":null,"abstract":"Objective: To examine the GFAP and S100B ability in prevention unnecessary brain Computed tomography (CT) scan in mild traumatic brain injury (mTBI) and compare them with the single extremity fracture in orthopedic patients.Methods: In this prospective cohort study, two orthopedics patients' groups and mTBI patients were studied to assess the biomarkers' ability in prevention unnecessary brain CT scan at the emergency setting. There were 40 orthopedics' patients with single extremity fracture and 41 mTBI patients. Brain CT scans were done for all mTBI patients.Results: Brain CT scans showed no intracranial traumatic lesions. The median levels for S100B in the mTBI group was 14.8 (4.4-335.9) ng/L, and in orthopedic patients' group was 13.3 (5-353.10) ng/L. Statistically significant differences were observed between both groups in S100B levels (p=0.006). The median Glial Fibrillary Acidic Protein (GFAP) levels in the mTBI patients' group were 600 (400-16300) and in the orthopedic patients' groups was 60 ng/L (300-14900). Statistically significant differences were observed between groups in GFAP (p=0.041).Conclusion: Our results showed that S100B and GFAP serum levels were significantly higher in patients with mTBI than in patients with a single limb fracture.","PeriodicalId":9333,"journal":{"name":"Bulletin of emergency and trauma","volume":"9 4","pages":"183-187"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39553546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3