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British journal of pharmaceutical research最新文献

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Bersama abyssinica Fresen. (Melianthaceae): Antifungal Activity on Aflatoxin B1-producing Mold Bersama abyssinica Fresen。(Melianthaceae):对产生黄曲霉毒素b1的霉菌的抗真菌活性
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/31695
K. Bene, A. Kra, K. Konan, G. Zirihi
{"title":"Bersama abyssinica Fresen. (Melianthaceae): Antifungal Activity on Aflatoxin B1-producing Mold","authors":"K. Bene, A. Kra, K. Konan, G. Zirihi","doi":"10.9734/BJPR/2017/31695","DOIUrl":"https://doi.org/10.9734/BJPR/2017/31695","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"9 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76352355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Development of Validated RP-HPLC Method for Simultanious Estimation of Cefadroxil and Ambroxol in Pure and Pharmaceutical Dosage Form 建立有效的反相高效液相色谱法同时测定头孢地洛辛和氨溴索纯剂型和制剂剂型的含量
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/bjpr/2017/32225
T. Singh, Dhiraj Kumar, A. Mishra, S. Arora, Durgesh Kumar, Sagar Pamu, H. B. Samal, Velupula Nishanth
{"title":"Development of Validated RP-HPLC Method for Simultanious Estimation of Cefadroxil and Ambroxol in Pure and Pharmaceutical Dosage Form","authors":"T. Singh, Dhiraj Kumar, A. Mishra, S. Arora, Durgesh Kumar, Sagar Pamu, H. B. Samal, Velupula Nishanth","doi":"10.9734/bjpr/2017/32225","DOIUrl":"https://doi.org/10.9734/bjpr/2017/32225","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"24 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79291919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring of Pesticide Poisoning in Different Occupational Groups by the Estimation of Serum Cholinesterase (PChE), ALT, AST & Bilirubin 不同职业人群血清胆碱酯酶(PChE)、谷丙转氨酶(ALT)、谷丙转氨酶(AST)和胆红素监测农药中毒
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/bjpr/2017/33468
H. M. Jamil, Mahamudul Haque, M. W. Rahman, T. Emran, R. Chowdhury, F. Nasrin, Chowdhoury Hasan
{"title":"Monitoring of Pesticide Poisoning in Different Occupational Groups by the Estimation of Serum Cholinesterase (PChE), ALT, AST & Bilirubin","authors":"H. M. Jamil, Mahamudul Haque, M. W. Rahman, T. Emran, R. Chowdhury, F. Nasrin, Chowdhoury Hasan","doi":"10.9734/bjpr/2017/33468","DOIUrl":"https://doi.org/10.9734/bjpr/2017/33468","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"35 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89801855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Mindfulness and Psychological Well-being and Coping Strategies with Stress among Female Basketball Athletes in Tehran 德黑兰女子篮球运动员正念与心理健康及压力应对策略的关系
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/34105
Z. Fazli, S. Ghahari
{"title":"The Relationship between Mindfulness and Psychological Well-being and Coping Strategies with Stress among Female Basketball Athletes in Tehran","authors":"Z. Fazli, S. Ghahari","doi":"10.9734/BJPR/2017/34105","DOIUrl":"https://doi.org/10.9734/BJPR/2017/34105","url":null,"abstract":"Introduction: The well-being and satisfaction with life are two indicators of mental health. The aim of this study was to evaluate the relationship between mindfulness and psychological well-being, and coping strategies with stress in female basketball athletes in Tehran. Methods and Materials: Among all women basketball athletes in Tehran in 2016, two-hundred and fifty women were randomly selected. All samples completed Lazarus and Folkman coping strategies questionnaire, Ryff Psychological well-being Questionnaire and Freiburg Mindfulness Inventory. Data were analyzed using Pearson correlation and multiple regression inSpss-22. Original Research Article Fazli and Ghahari; BJPR, 17(2): 1-8, 2017; Article no.BJPR.34105 2 Results: The results confirmed the hypothesis of this study and suggested a significant positive relationship between the components of mindfulness and psychological well-being, and coping with stress strategies (p<0.01). Conclusion: There was a significant positive relationship between components of mindfulness and psychological well-being, and coping strategies with stress.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"1 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89685453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative Study for In-vitro Evaluation of Metronidazole Prepared Using Natural Chitosan from Oyster Shells of Egeria radiata 天然壳聚糖制备甲硝唑体外评价的比较研究
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/33247
S. Majekodunmi, Ekefre-Abasi Akpan
{"title":"Comparative Study for In-vitro Evaluation of Metronidazole Prepared Using Natural Chitosan from Oyster Shells of Egeria radiata","authors":"S. Majekodunmi, Ekefre-Abasi Akpan","doi":"10.9734/BJPR/2017/33247","DOIUrl":"https://doi.org/10.9734/BJPR/2017/33247","url":null,"abstract":"Objective: The present study investigates the capability of preparing metronidazole loaded microspheres employing a natural chitosan extracted from oyster shells of Egeria radiata. Methods: Microspheres were prepared by external gelation technique using tripolyphosphate (TPP) as the cross-linker. The drug to polymer ratio was selected at various levels of polymer-drug quantities with varying amount of TPP. The prepared microspheres were characterized for % yield, drug entrapment efficiency, surface morphology and drug release profile. Results: Almost spherical, rough and porous microspheres were obtained. % yield and drug entrapment efficiency were found to be in the range of 63.5 – 70.8% and 63.4 – 77.5% respectively; and about 80% of the drug was released in about 6 hours. Conclusion: The results revealed that formulation of metronidazole loaded microspheres in natural chitosan from an oyster shell can be used as a potential oral drug delivery system. Original Research Article Majekodunmi and Akpan; BJPR, 17(1): 1-11, 2017; Article no.BJPR.33247 2","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"26 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78213451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Anti-Cancerous Efficacy of Alcoholic and Aqueous Extracts from an Endemic Plant Thermopsis turcica on Liver Carcinoma 特有种植物大黄草醇提物和水提物对肝癌的抗癌作用
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/32413
M. Ali, İ. Ciğerci
{"title":"Anti-Cancerous Efficacy of Alcoholic and Aqueous Extracts from an Endemic Plant Thermopsis turcica on Liver Carcinoma","authors":"M. Ali, İ. Ciğerci","doi":"10.9734/BJPR/2017/32413","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32413","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"26 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84995330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Anti-Mycobacterium Metabolite from Marine Sponge Iricinia fusca 海海绵鸢尾抗分枝杆菌代谢物
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/bjpr/2017/32881
S. Meesala, Ruby Singh, M. Watve
{"title":"Anti-Mycobacterium Metabolite from Marine Sponge Iricinia fusca","authors":"S. Meesala, Ruby Singh, M. Watve","doi":"10.9734/bjpr/2017/32881","DOIUrl":"https://doi.org/10.9734/bjpr/2017/32881","url":null,"abstract":"Chemical investigation of the marine sponge Ircinia fusca leads to isolation of a new pyrrole derivative (1) and two known compounds namely, 3 methyl decanoic acid (2) and Benzenedicarboxylic acid (3). The structures of compounds were established by 1D and 2D NMR and MS data. Compound 1 exhibited strong antibacterial activity against Mycobacterium smegmatis at MIC 116 μM. Compounds 1-3 showed neither antifungal nor cytotoxic activity.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"12 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75444865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pharmacokinetic Characterization of Piperaquine in Nigerian Healthy Volunteers after Co-administration with a Commercial Brand of Moringa Tea 尼日利亚健康志愿者与商业品牌辣木茶共同给药后哌喹的药动学特征
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/32723
Alero Iseh, A. Adegbola, B. Adeagbo
{"title":"Pharmacokinetic Characterization of Piperaquine in Nigerian Healthy Volunteers after Co-administration with a Commercial Brand of Moringa Tea","authors":"Alero Iseh, A. Adegbola, B. Adeagbo","doi":"10.9734/BJPR/2017/32723","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32723","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"63 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74828275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiangiogenic and Apoptotic Effects of Oleuropein on Breast Cancer Cells 橄榄苦苷对乳腺癌细胞的抗血管生成和凋亡作用
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/33403
R. Liman, F. Çoban, İ. Ciğerci, I. Bulduk, Ş. Bozkurt
{"title":"Antiangiogenic and Apoptotic Effects of Oleuropein on Breast Cancer Cells","authors":"R. Liman, F. Çoban, İ. Ciğerci, I. Bulduk, Ş. Bozkurt","doi":"10.9734/BJPR/2017/33403","DOIUrl":"https://doi.org/10.9734/BJPR/2017/33403","url":null,"abstract":"Oleuropein is a fundamental polyphenol contained in olive fruit, oil, and leaf, with a bitter taste. A decrease in its level is observed as the fruit ripens. Leaves of oil tree were used in this study as a possible origin of oleuropein. In this study, cytotoxic, genotoxic, apoptotic and antiangiogenic impacts of isolated oleuropein (0.5xIC50, IC50 and 2xIC50) on MCF-7 human breast adenocarcinoma cells were examined by means of 3-[4,5Dimethylthiazol-2-yl] 1-2,5diphenyltetrazolium bromide (XTT) kit, Comet assay, Poly (ADP-Ribose) Polymerase (PARP) cleavage ELISA Kit and Vascular Endothelial Growth Factor (VEGF) Human ELISA Kit for 24, 48 and 72 h, respectively. The IC50 value of oleuropein on MCF-7 cells was found to be 11.02±0.52, 9.43±0.41 and 6.81±0.18 μg/mL for 24, 48 and 72 h, respectively. The time and concentrationrelated cytotoxic impacts of oleuropein were determined to be significant. Cleaved PARP level was Original Research Article Liman et al.; BJPR, 16(4): 1-10, 2017; Article no.BJPR.33403 2 significantly increased especially with an increase in the concentration of oleuropein. However, a significant decrease in VEGF level was observed (p<0.05). Furthermore, oleuropein increased damage on DNA for 48 and 72 h. Findings showed oleuropein as a potential antiangiogenic, apoptotic and genotoxic agent for the breast cancer cells.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"72 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75675729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Comparison of the Effects of Ropivacaine and Bupivacaine on Human Umblical Artery Vasoreactivity 罗哌卡因与布比卡因对人脐动脉血管反应性影响的比较
British journal of pharmaceutical research Pub Date : 2017-01-10 DOI: 10.9734/BJPR/2017/32591
K. Nurten, Dalaklioğlu Selvinaz, Bigat Zekiye, Karsli Bilge, Tasatargil Arda
{"title":"Comparison of the Effects of Ropivacaine and Bupivacaine on Human Umblical Artery Vasoreactivity","authors":"K. Nurten, Dalaklioğlu Selvinaz, Bigat Zekiye, Karsli Bilge, Tasatargil Arda","doi":"10.9734/BJPR/2017/32591","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32591","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"13 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79395826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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