{"title":"海海绵鸢尾抗分枝杆菌代谢物","authors":"S. Meesala, Ruby Singh, M. Watve","doi":"10.9734/bjpr/2017/32881","DOIUrl":null,"url":null,"abstract":"Chemical investigation of the marine sponge Ircinia fusca leads to isolation of a new pyrrole derivative (1) and two known compounds namely, 3 methyl decanoic acid (2) and Benzenedicarboxylic acid (3). The structures of compounds were established by 1D and 2D NMR and MS data. Compound 1 exhibited strong antibacterial activity against Mycobacterium smegmatis at MIC 116 μM. Compounds 1-3 showed neither antifungal nor cytotoxic activity.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"12 1","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Anti-Mycobacterium Metabolite from Marine Sponge Iricinia fusca\",\"authors\":\"S. Meesala, Ruby Singh, M. Watve\",\"doi\":\"10.9734/bjpr/2017/32881\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chemical investigation of the marine sponge Ircinia fusca leads to isolation of a new pyrrole derivative (1) and two known compounds namely, 3 methyl decanoic acid (2) and Benzenedicarboxylic acid (3). The structures of compounds were established by 1D and 2D NMR and MS data. Compound 1 exhibited strong antibacterial activity against Mycobacterium smegmatis at MIC 116 μM. Compounds 1-3 showed neither antifungal nor cytotoxic activity.\",\"PeriodicalId\":9320,\"journal\":{\"name\":\"British journal of pharmaceutical research\",\"volume\":\"12 1\",\"pages\":\"1-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British journal of pharmaceutical research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9734/bjpr/2017/32881\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/bjpr/2017/32881","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-Mycobacterium Metabolite from Marine Sponge Iricinia fusca
Chemical investigation of the marine sponge Ircinia fusca leads to isolation of a new pyrrole derivative (1) and two known compounds namely, 3 methyl decanoic acid (2) and Benzenedicarboxylic acid (3). The structures of compounds were established by 1D and 2D NMR and MS data. Compound 1 exhibited strong antibacterial activity against Mycobacterium smegmatis at MIC 116 μM. Compounds 1-3 showed neither antifungal nor cytotoxic activity.
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