Journal of Health Science and Medical Research (JHSMR)最新文献

Prehospital Time Intervals in Thailand during COVID-19 2019冠状病毒病期间泰国院前时间间隔

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-13 DOI: 10.31584/jhsmr.20231013

Patiman Chanrak, Kanthika Kraisawat

{"title":"Prehospital Time Intervals in Thailand during COVID-19","authors":"Patiman Chanrak, Kanthika Kraisawat","doi":"10.31584/jhsmr.20231013","DOIUrl":"https://doi.org/10.31584/jhsmr.20231013","url":null,"abstract":"Objective: To determine the effect of the coronavirus disease, 2019 (COVID-19) pandemic on the prehospital time intervals of emergency medical services (EMS) in Thailand. Material and Methods: This retrospective cohort study analyzed the prehospital time intervals of EMS in Thailand; from January 1, 2019 to September 30, 2021 using data obtained from the national EMS database. Patients with incomplete medical records, prehospital time intervals <1 or >300 minutes, and those admitted between January 1 and March 31, 2020 were excluded. Data were compared between the following groups: Group 1, pre-COVID-19; Group 2, first- and second-wave of COVID-19; and Group 3, third-wave of COVID-19: Kruskal–Wallis, Wilcoxon rank-sum, and chi-square tests were used. Results: A total of 3,863,153 patients were enrolled into this study. The median total prehospital time was significantly longer in Group 2 when compared to Group 1, [25 (17,34) vs. 24 (17,33) minutes, p-value<0.001]; longer on-scene time, [4 (2,7) vs. 3 (2,6) minutes, p-value<0.001]; shorter transportation time, [10 (6,17) vs. 11 (6,18) minutes, p-value<0.001]. The median total prehospital time [27 (19,37) vs. 25 (17,34) minutes, p-value<0.001], response time [8 (5,14) vs. 7 (4,11) minutes, p-value<0.001], and transportation time were significantly longer in Group 3 than in Group 2 [11 (6,18) vs. 10 (6,17) minutes, p-value<0.001]. Conclusion: The EMS prehospital time intervals in Thailand during COVID-19 were significantly longer in both the non-trauma and trauma subgroups. Appropriate pre-hospital strategies and monitoring should be developed to manage future pandemics.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"51 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136346560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthesia For Patients Receiving Single-Lung Transplantation in Non-Pulmonary Surgical Intervention: A Case Report 非肺外科干预中单肺移植患者的麻醉:1例报告

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-09 DOI: 10.31584/jhsmr.20231012

Laortip Rattanapittayaporn, Mantana Saetang, Wirat Wasinwong, Jutarat Tanasansuttiporn

引用次数: 0

Establishment of Thin Layer Chromatographic Fingerprints for the Quality Control of Chanthalila Preparation, A Thai Traditional Antipyretic Medicine 泰国传统解热药鸡头菜制剂质量控制的薄层色谱指纹图谱建立

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-07 DOI: 10.31584/jhsmr.20231010

Dujhathai Anekchai, Athip Sakunphueak

{"title":"Establishment of Thin Layer Chromatographic Fingerprints for the Quality Control of Chanthalila Preparation, A Thai Traditional Antipyretic Medicine","authors":"Dujhathai Anekchai, Athip Sakunphueak","doi":"10.31584/jhsmr.20231010","DOIUrl":"https://doi.org/10.31584/jhsmr.20231010","url":null,"abstract":"Objective: This study aimed to develop thin layer chromatographic (TLC) fingerprints to control the quality of Chanthalila preparation (CP).Material and Methods: Twelve batches of reference CP were prepared from various sources and used as reference batches (CP1 to CP12). Artemisinin, atractylodin, eurycomanone, imperatorin and loureirin A were used as markers. The common and characteristic bands were assigned using the reference TLC fingerprints and applied to assess the qualitative parameters used in the identification and chemical profiling of eight commercial CPs.Results: The reference TLC fingerprints were established on a silica gel GF254 plate with two mobile phase systems, System A and System B. In System A, atractylodin, imperatorin, and loureirin A were assigned as characteristic bands along with 10-12 common bands under Ultraviolet (UV) 254 nm, UV 366 nanometer (nm), and derivatization. In System B, 6 common bands were observed under UV 254 nm, while 11 fluorescent bands were detected under UV 366 nm. Eurycomanone and artemisinin were not found in any reference CP batches, which revealed the TLC method had poor sensitivity. The TLC patterns of commercial CPs were markedly different from those of the reference fingerprints. Most commercial products failed to meet the specification criteria because only imperatorin appeared in the chromatogram.Conclusion: TLC fingerprinting is a fast and efficient method that can be employed in the quality control of CP. It enables the revelation of the quality of the raw materials in the chromatograms, which can be useful to manufacturers to evaluate their supplier sources. However, the sensitivity of this method for determining some markers was quite low.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"52 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135432090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Fibre Consumption in a Sample of Italian Adults: Relationship Between Dietary Habits and Gender, Ponderal Status and Physical Activity 意大利成年人的膳食纤维摄入量:饮食习惯与性别、身体状况和体力活动之间的关系

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-07 DOI: 10.31584/jhsmr.20231011

Myriam Galfo, Fabrizia Maccati, Francesca Melini, Valentina Melini

{"title":"Dietary Fibre Consumption in a Sample of Italian Adults: Relationship Between Dietary Habits and Gender, Ponderal Status and Physical Activity","authors":"Myriam Galfo, Fabrizia Maccati, Francesca Melini, Valentina Melini","doi":"10.31584/jhsmr.20231011","DOIUrl":"https://doi.org/10.31584/jhsmr.20231011","url":null,"abstract":"Objective: The aim of this study was to investigate the consumption frequency of foods rich in dietary fibre; in relation to gender, ponderal status and physical activity, in a sample of Italian adults.Material and Methods: A cross-sectional online survey was conducted; from November 2021 to June 2022, on 300 subjects by a questionnaire on sociodemographic characteristics, lifestyle behaviours and consumption frequency of dietary fibre-rich foods.Results: The consumption frequency of dietary fibre is higher in females than in males. A higher percentage of obese people never or rarely consumed foods rich in dietary fibre. In regards to the consumption of whole-meal biscuits/whole-meal rusks/whole grains, it was observed that a higher percentage of overweight subjects ate them every day, more so than those who were obese, of normal-underweight and in overweight females; with the difference being significant (52.6% vs 16.7% and 32.6%; p-value=0.0366). The same trend was observed for fruit and vegetable consumption; wherein, 11.1% of overweight participants consumed 5 or more servings per day of fruit and vegetables. In contrast, only 7.9% of normal-underweight and 3.6% of obese behave according to WHO recommendations. In overweight females, this difference was significant (12.8% vs 8.3% and 8.3%; p-value=0.0103). A significant (p-value<0.05) higher consumption of dietary fibre was observed in physically active people than in physical inactive people, while no significant differences existed between those who exercise for at least 150 minutes/week and those who exercise less than 150minutes.Conclusion: Dietary fibre consumption was moderately associated with gender and weight status and significantly associated with physical activity.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"52 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135432085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrospinning of Polycaprolactone Nanofibrous Scaffolds Containing Folic Acid for Nerve Tissue Engineering 静电纺丝制备含叶酸聚己内酯纳米纤维支架用于神经组织工程

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-06 DOI: 10.31584/jhsmr.20231007

Rattanan Thaitrong, Praneet Opanasopit, Natthan Charernsriwilaiwat

{"title":"Electrospinning of Polycaprolactone Nanofibrous Scaffolds Containing Folic Acid for Nerve Tissue Engineering","authors":"Rattanan Thaitrong, Praneet Opanasopit, Natthan Charernsriwilaiwat","doi":"10.31584/jhsmr.20231007","DOIUrl":"https://doi.org/10.31584/jhsmr.20231007","url":null,"abstract":"Objective: The aim of the study was to employ electrospinning technology to fabricate aligned nanofibrous scaffolds of polycaprolactone (PCL) containing folic acid (FA) for nerve tissue engineering. Material and Methods: Scanning electron microscopy (SEM) was used to assess the diameter distribution and degree of alignment of the nanofibers. Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (PXRD) were used to analyze the chemical and crystalline structures of the scaffold. Additionally, the content and release behavior of FA in the PCL fibrous scaffolds were examined. Finally, the biocompatibility of the scaffolds was evaluated using rat Schwann cells, assessing cell proliferation, alignment, and morphology. Results: The study revealed that the nanofiber diameters ranged from 210.07 to 227.36 nm, and the scaffolds maintained an amorphous form with no effects on their chemical structure following the electrospinning process. The investigation demonstrated that PCL fibers could accommodate FA loading within a range of 99.25-102.49% w/w and that the release profile of FA followed Higuchi model. Moreover, the FA-containing PCL nanofibrous scaffolds significantly enhanced rat Schwann cell proliferation during the initial two days of culture when compared to a normal PCL nanofiber scaffold. The hydrophilic properties of folic acid are thought to have facilitated directional growth along the electrospun nanofibers, contributing to the observed results. Conclusion: Finally, PCL-containing FA nanofibrous scaffolds may be applicable to nerve tissue engineering.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135634628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the Impact of Feeding Stray Dogs on Stray Dog-Related Issues: A Community-Based Study in Songkhla, Thailand 评估喂养流浪狗对流浪狗相关问题的影响:泰国宋卡的一项社区研究

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-06 DOI: 10.31584/jhsmr.20231008

Afia Saree, Anda Klinpikul, Apissara Kongchu, Arya Wongaree, Bussabong Navykarn, Chaowanet Songsakul, Chayapa Kongsuwan, Chuttama Kiewlek, Hillmee Waesalaemae, Isarawadee Sarasutjari, Jehrusdee Benjama, Napak Thongprasert, Nathchanon Sukchaiya, Nititon Suksai, Pakjira Jongthitinon, Pattiya Chorueangsak, Pattamaporn Kiattisaksophon, Pawanya Boonbandan, Phansang Sanguthai, Ponnapat Apiwatgaroon, Pornlapat Rattanakhot, Prapasiri Poomivanichakij, Sattawat Kao-ian, Supatcha Thongchai, Surathep Ongprakobkul, Tanabadee Sritulakan, Thanatcha Saisrikosol, Sikarin Sae Jong, Jutapoln Sunghan, Panya Chamroonkiadtikun, Polathep Vichitkunakorn

{"title":"Assessing the Impact of Feeding Stray Dogs on Stray Dog-Related Issues: A Community-Based Study in Songkhla, Thailand","authors":"Afia Saree, Anda Klinpikul, Apissara Kongchu, Arya Wongaree, Bussabong Navykarn, Chaowanet Songsakul, Chayapa Kongsuwan, Chuttama Kiewlek, Hillmee Waesalaemae, Isarawadee Sarasutjari, Jehrusdee Benjama, Napak Thongprasert, Nathchanon Sukchaiya, Nititon Suksai, Pakjira Jongthitinon, Pattiya Chorueangsak, Pattamaporn Kiattisaksophon, Pawanya Boonbandan, Phansang Sanguthai, Ponnapat Apiwatgaroon, Pornlapat Rattanakhot, Prapasiri Poomivanichakij, Sattawat Kao-ian, Supatcha Thongchai, Surathep Ongprakobkul, Tanabadee Sritulakan, Thanatcha Saisrikosol, Sikarin Sae Jong, Jutapoln Sunghan, Panya Chamroonkiadtikun, Polathep Vichitkunakorn","doi":"10.31584/jhsmr.20231008","DOIUrl":"https://doi.org/10.31584/jhsmr.20231008","url":null,"abstract":"Objective: Increasing stray dog populations have transformed stray dog issues from a third-world problem to a global public health priority. This study aimed to determine factors related to feeding stray dogs and other factors that can impact stray dog-related issues. Material and Methods: This community-based cross-sectional study was conducted in Songkhla, Thailand, from the 4th to the 29th of January 2021. Data was collected via phone interviews. Logistic regression was performed to measure the association between the independent variables and problems related to stray dogs. Results: Among 168 participants, 137 (81.5%) reported having experienced a negative impact in connection with problems caused by stray dogs. The most common problem was garbage scavenging (62.5%), which predominantly occurred between 18:00 and midnight. Feeding stray dogs was significantly associated with stray dog-related problems (odds ratio [OR]=3.94 with a 95% confidence interval [CI] 1.26-17.41). Conclusion: Providing food to stray dogs causes problems and is also prohibited by law. It is important for media, community leaders, and other influential groups to create awareness and foster cooperation among communities to address this issue.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135635434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical Analysis and Evaluation of Antioxidant and Antibacterial Activities of Kratom-Containing Formulations of Ya-Gae-Bid-Na-Ron 含紫丁香制剂抗氧化、抗菌活性的植物化学分析与评价

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-03 DOI: 10.31584/jhsmr.20231006

Suhaila Doloh, Boonsong Wungsintaweekul, Juraithip Wungsintaweekul

{"title":"Phytochemical Analysis and Evaluation of Antioxidant and Antibacterial Activities of Kratom-Containing Formulations of Ya-Gae-Bid-Na-Ron","authors":"Suhaila Doloh, Boonsong Wungsintaweekul, Juraithip Wungsintaweekul","doi":"10.31584/jhsmr.20231006","DOIUrl":"https://doi.org/10.31584/jhsmr.20231006","url":null,"abstract":"Objective: This study aimed to evaluate the antioxidant and antibacterial activities of Ya-Gae-Bid-Na-Ron (YGBNR).Material and Methods: YGBNR formulations were prepared using kratom collected from different provinces in Thailand. Mitragynine content was determined using high-performance liquid chromatography (HPLC), while total phenolic content (TPC), total tannin content (TTC), and total flavonoid content (TFC) were determined using colorimetric methods. Antioxidant power was estimated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric-reducing antioxidant power (FRAP) assays. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of YGBNR were determined using a broth dilution technique and plating of the bacterial solution, respectively.Results: Mitragynine content, TPC, TTC, and TFC varied among different sources of kratom. DPPH assay indicated that YGBNR had an average IC50 of 0.44±0.04 mg/mL, and the FRAP assay ranged from 61.48±0.55 to 102.98±0.94 mg gallic acid equivalent (GAE), per gram of dry extract. YGBNR extracts did not exhibit any antibacterial activity. However, the volatile oil fraction showed MIC against Escherichia coli and Pseudomonas aeruginosa at a concentration of 3 mg/mL.Conclusion: Phytochemical analysis revealed the abundance of phenolic compounds in YGBNR. YGBNR exhibits promising antioxidant potential, but does not exert any antibacterial activity.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"104 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135869143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Development of Nanoparticles Containing α-Mangostin for Wound Application 伤口用α-山竹苷纳米颗粒的设计与研制

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-11-01 DOI: 10.31584/jhsmr.20231005

Peerapat Chidchai, Kanokwan Singpanna, Kamonchai Ketduang, Aristarn Uamjan, Prasopchai Patrojanasophon, Chaiyakarn Pornpitchanarong

{"title":"Design and Development of Nanoparticles Containing α-Mangostin for Wound Application","authors":"Peerapat Chidchai, Kanokwan Singpanna, Kamonchai Ketduang, Aristarn Uamjan, Prasopchai Patrojanasophon, Chaiyakarn Pornpitchanarong","doi":"10.31584/jhsmr.20231005","DOIUrl":"https://doi.org/10.31584/jhsmr.20231005","url":null,"abstract":"Objective: The objective of this research was to design and develop nanoparticles containing α-mangostin (α-MG) for wound applications. Material and Methods: The nanoparticles were composed of polycaprolactone (PCL) and Eudragit® S 100 (EDG), with 10% wt of α-MG; wherein, the optimal compositions of the nanoparticles were studied using a mixture-typed simplex lattice design. The amount of PCL (5-20 milligram/milliliter (mg/mL)) and EDG (5-20 mg/mL) were varied, and the effects of the components toward particle size, size distribution, zeta potential; drug content, and drug release were examined. The physicochemical properties of the nanoparticles were analyzed using a zetasizer. The content of α-MG was quantified using High Pressure Liquid Chromatography. Results: It was found that the nanoparticles having different mixtures of PCL and EDG did not affect the physicochemical properties nor the drug content. However, the release of α-MG can be tuned by varying the nanoparticle composition. Formulations with higher EDG showed greater drug release at pH 7.4, because of the polymer dissolution at a specified pH. The composition of the optimized formulation composed of 16.5 mg/mL of EDG and 8.5 mg/mL of PCL. The optimized nanoparticle showed a controlled release profile of up to 12 h, which was superior to the α-MG solution. Conclusion: The developed nanoparticles of PCL and EDG can be considered as a promising platform to deliver α-MG for wound applications.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"284 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135273653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vitro Bioactivities of Alcohol-Free Benzydamine Oromucosal Solutions 无醇苄胺口腔粘膜溶液的体外生物活性研究

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-10-31 DOI: 10.31584/jhsmr.20231002

Suwipa Ungphaiboon, Sutasinee Ardhanwanich, Sonsawan Kongpuckdee, Duangkhae Maneenuan, Teerapol Srichana

{"title":"In Vitro Bioactivities of Alcohol-Free Benzydamine Oromucosal Solutions","authors":"Suwipa Ungphaiboon, Sutasinee Ardhanwanich, Sonsawan Kongpuckdee, Duangkhae Maneenuan, Teerapol Srichana","doi":"10.31584/jhsmr.20231002","DOIUrl":"https://doi.org/10.31584/jhsmr.20231002","url":null,"abstract":"Objective: This research aimedto evaluate the effects of chitosan and poloxamer 407 on in vitro cytotoxicity, anti-inflammatory, wound healing, and antimicrobial activities of 0.3% w/v benzydamine hydrochloride (HCl) oromucosal solutions.Material and Methods: The effects of three alcohol-free benzydamine HCl oromucosal formulations; containing: 1) 0.5% w/v chitosan, 2) 15% w/v poloxamer 407, and 3) a combination of 0.5% w/v chitosan and 15% w/v poloxamer 407, on in vitro cytotoxicity and biological activities were evaluated and compared to a commercial benzydamine HCl mouth spray, containing alcohol and 0.12% chlorhexidine solution.Results: All alcohol-free benzydamine HCl formulations and their vehicles were less cytotoxic to the macrophage RAW 264.7 cell line than the commercial spray and to the human gingival fibroblast cell line than chlorhexidine, respectively. The formulation containing 0.5% w/v chitosan exhibited the highest wound healing activity on the fibroblast cells among all tested products, and showed anti-inflammatory activity on macrophage cells, which is comparable to benzydamine HCl. Furthermore, from the time-kill assay, this formulation completely inhibited Streptococcus mutans within 1 minute, similar to 0.12% chlorhexidine solution, and reduced the cell number of Candida albicans more rapidly than the commercial spray.Conclusion: The alcohol-free benzydamine HCl solution containing 0.5% w/v chitosan as a mucoadhesive polymer is a promising oral care candidate, which is safe to be used, and has wound healing, anti-inflammatory, and antimicrobial activities.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"33 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135808731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contrast-enhanced Computed Tomography Versus Contrast and Non-contrast Enhanced Computed Tomography for Detecting Blunt Abdominal Injury 对比增强计算机断层扫描与对比增强和非对比增强计算机断层扫描检测钝性腹部损伤

Journal of Health Science and Medical Research (JHSMR) Pub Date : 2023-10-31 DOI: 10.31584/jhsmr.20231003

Kornkanok Naraweerawut, Kamonwon Cattapan, Panjai Choochuen, Khanin Khanungwanitkul

{"title":"Contrast-enhanced Computed Tomography Versus Contrast and Non-contrast Enhanced Computed Tomography for Detecting Blunt Abdominal Injury","authors":"Kornkanok Naraweerawut, Kamonwon Cattapan, Panjai Choochuen, Khanin Khanungwanitkul","doi":"10.31584/jhsmr.20231003","DOIUrl":"https://doi.org/10.31584/jhsmr.20231003","url":null,"abstract":"Objective: This study aimed to compare the diagnostic ability of contrast-enhanced computed tomography (CECT) and CECT combined with non-contrast computed tomography (NCT) for intraabdominal organ injury in patients with blunt abdominal injury.Material and Methods: Overall, 195 adult patients having had blunt abdominal trauma underwent CT at this institution; from 2016 and 2021. All CT images were retrospectively reviewed by two radiologists. The efficacy of detection of organ injuries and the degree of intra-abdominal injury were recorded. The radiologists scored their diagnostic confidence for each CT image dataset on a five-point scale: inter-observer agreement was also calculated.Results: All included patients underwent CT for blunt abdominal trauma. The most common cause of injury was motorcycle accident (59.5%), with patients being predominantly male: the mean patient age was 44 years. Hemoperitoneum was the most common CT finding, with a significantly higher detection rate on CECT combined with NCT than on CECT alone. There was no statistically significant difference in the diagnostic efficacy of the detected organ injury nor other types of organ injuries between CECT alone and CECT combined with NCT. Nevertheless, the accuracy of CECT in detecting hemoperitoneum may diminish in patients with severe fatty liver disease; especially in the perihepatic region.Conclusion: CECT alone is a potential tool for detecting abdominal injuries in patients with blunt trauma. NCT provides no additional benefits in detecting organ injury; except in cases of severe fatty liver disease. NCT is recommended as an optional protocol; particularly for patients with obesity.","PeriodicalId":93205,"journal":{"name":"Journal of Health Science and Medical Research (JHSMR)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0