British Journal of Ophthalmology最新文献_第9页

Nationwide age-, sex-, cause-specific burden of blindness and vision impairment in China. 全国不同年龄、性别、病因的失明和视力损害负担。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-20 DOI: 10.1136/bjo-2025-327389

Xiao Guo, Ruilin Xiong, Jingwei Yao, Huangdong Li, Ziyu Zhu, Yanping Chen, Wenyong Huang, Mingguang He, Wei Wang

{"title":"Nationwide age-, sex-, cause-specific burden of blindness and vision impairment in China.","authors":"Xiao Guo, Ruilin Xiong, Jingwei Yao, Huangdong Li, Ziyu Zhu, Yanping Chen, Wenyong Huang, Mingguang He, Wei Wang","doi":"10.1136/bjo-2025-327389","DOIUrl":"10.1136/bjo-2025-327389","url":null,"abstract":"Background: Despite over 90% of vision impairment (VI) being preventable, in China, a routine screening programme is currently unavailable in primary healthcare. Robust epidemiological evidence is needed to guide national strategies.Method: Using Global Burden of Disease 2021 data, we estimated prevalence, years lived with disability (YLDs), and age-standardized rates of VI by cause and severity. Temporal changes were decomposed into contributions from population growth, ageing, and shifts in age-specific prevalence. Estimated annual percentage changes (EAPCs) assessed trends, and Bayesian age-period-cohort models projected burden to 2040.Results: In 2021, China had 767.4 million (95% UI 576.6 to 1009.3) VI cases, comprising: 324.4 million (237.7 to 435.4) uncorrected presbyopia, 4.1 million (3.4 to 5.0) moderate VI, 46.7 million (39.4 to 55.3) severe VI and 8.6 million (7.0 to 10.2) blindness. Population ageing emerged as the predominant driver, accounting for 164.25% of the cataract-related burden increase. Women had a higher burden than men (53.79% of cases; 54.87% of YLDs), and the burden peaked at older ages. Uncorrected refractive errors and cataracts were the leading aetiologies, constituting 50.65% of moderate VI and 35.08% of blindness. Projections indicate that by 2040, the age-standardised YLD rate for VI may nearly double from 2021 levels, reaching 596.4 (95% UI 72.0 to 1240.4) per 100 000 population.Conclusions: VI is a growing public health challenge in China, driven primarily by ageing. Many cases are preventable, underscoring the need for targeted interventions, particularly among women and older adults.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":"1002-1011"},"PeriodicalIF":4.5,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146099701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes of and a risk score model for moderate-risk to high-risk penetrating keratoplasty. 中危至高危穿透性角膜移植术的长期预后及风险评分模型。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-20 DOI: 10.1136/bjo-2025-328901

Zhewen Zheng, Yangqi Zhang, Wenyan Peng, Xueqin Gong, Jinyu Zhang, Chunxiao Wang, Shiyou Zhou

{"title":"Long-term outcomes of and a risk score model for moderate-risk to high-risk penetrating keratoplasty.","authors":"Zhewen Zheng, Yangqi Zhang, Wenyan Peng, Xueqin Gong, Jinyu Zhang, Chunxiao Wang, Shiyou Zhou","doi":"10.1136/bjo-2025-328901","DOIUrl":"10.1136/bjo-2025-328901","url":null,"abstract":"Background/aims: To develop a risk score for moderate-risk to high-risk penetrating keratoplasty (PK) based on various risk factors and use it to stratify grafts.Methods: We collected data on clinical features and survival status from the electronic health records of patients who underwent moderate-risk to high-risk PK between January 2012 and December 2021. Feature selection was performed using multivariate Cox regression analyses. The risk score was derived from the coefficient of variables obtained through the Cox proportional hazards model. The performance of the risk score was assessed using receiver operating characteristic curve analysis. Risk stratification was performed based on the risk scores.Results: The study cohort comprised 2297 eyes (2166 patients) subjected to moderate-risk to high-risk PK. The risk score was derived based on six variables. Each variable was assigned a score of 0, 1, 2 or 3 based on its coefficient. The discriminative ability of this score was robust, achieving an area under the receiver operating characteristic curve of 0.747 in the external validation cohort, which surpassed the predictive performance of any single variable alone. According to the established risk score, patients were stratified into three distinct prognostic subgroups: moderate-risk (0-2 points), high-risk (3-5 points) and extremely high-risk groups (≥6 points). The survival curves across these stratified groups differed significantly (log-rank test, p<0.001).Conclusion: The risk score demonstrated good discriminatory ability for moderate-risk to high-risk PK and can help to further stratify these grafts.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":"981-989"},"PeriodicalIF":4.5,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Manchester buckle study: 15-year outcomes and predictive factors for success in scleral buckling for primary rhegmatogenous retinal detachment. 曼彻斯特扣环研究：原发性孔源性视网膜脱离巩膜扣环成功的15年结果和预测因素。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-20 DOI: 10.1136/bjo-2025-328525

Myrta Lippera, Peter Kiraly, Naseer Ally, Nouf Alnafisee, Ritu Agarwal, Assad Jalil, Tsveta Ivanova, George Moussa, Felipe Dhawahir-Scala, Niall Patton, George Turner, Stephen Charles, Kirti Jasani

{"title":"The Manchester buckle study: 15-year outcomes and predictive factors for success in scleral buckling for primary rhegmatogenous retinal detachment.","authors":"Myrta Lippera, Peter Kiraly, Naseer Ally, Nouf Alnafisee, Ritu Agarwal, Assad Jalil, Tsveta Ivanova, George Moussa, Felipe Dhawahir-Scala, Niall Patton, George Turner, Stephen Charles, Kirti Jasani","doi":"10.1136/bjo-2025-328525","DOIUrl":"10.1136/bjo-2025-328525","url":null,"abstract":"Aims: To assess the long-term anatomical and visual outcomes of primary scleral buckle (SB) surgery for rhegmatogenous retinal detachment (RRD) and identify predictors of surgical and functional success.Methods: All primary SB procedures performed at Manchester Royal Eye Hospital between January 2008 and December 2023 were reviewed retrospectively. Preoperative, intraoperative and postoperative data were extracted from electronic records. Primary end-points were single-surgery anatomical success (SSAS) and final best-corrected visual acuity (BCVA); univariate and multivariate regression analyses examined predictive variables and complications.Results: 608 eyes were included. SSAS was achieved in 515 eyes (85%) and final anatomical success in 602 eyes (99%). Mean BCVA improved from 0.62±0.85 to 0.32±0.49 logarithm of the minimum angle of resolution (logMAR) (p<0.01). On multivariate analysis, age >40 years (OR 0.55, 95% CI 0.37 to 0.83; p=0.004), macula-off status (OR 0.65, 95% CI 0.44 to 0.97; p=0.034) and ocular trauma (OR 0.40, 95% CI 0.19 to 0.82; p=0.012) independently reduced SSAS. For visual outcomes, macula-off detachment (β=+0.36; p<0.001) and ocular trauma (β=+0.42; p<0.001) were independent predictors of worse postoperative BCVA. The most common complications were subretinal haemorrhage (4.6%), inadvertent deep sutures (3.9%) and postoperative ocular hypertension (7.4%).Conclusions: Primary SB provided high anatomical success, significant visual improvement and a favourable safety profile in this large single-centre study. Age above 40 years, macula-off status and ocular trauma predicted poorer SSAS; trauma and macula-off status were also associated with worse postoperative BCVA on multivariate logistic regression.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":"1070-1075"},"PeriodicalIF":4.5,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitomycin C-based angio-regression for corneal neovascularisation: outcomes with intravascular (MICE), intrastromal (MIST) and combined delivery routes. 基于丝裂霉素c的血管消退治疗角膜新生血管：血管内（MICE）、基质内（MIST）和联合给药途径的结果

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-20 DOI: 10.1136/bjo-2026-329997

Alice L Milligan, Alexander C Day, Su-Yin Koay, Mark Wilkins, Vincenzo Maurino, Martin Watson

{"title":"Mitomycin C-based angio-regression for corneal neovascularisation: outcomes with intravascular (MICE), intrastromal (MIST) and combined delivery routes.","authors":"Alice L Milligan, Alexander C Day, Su-Yin Koay, Mark Wilkins, Vincenzo Maurino, Martin Watson","doi":"10.1136/bjo-2026-329997","DOIUrl":"10.1136/bjo-2026-329997","url":null,"abstract":"Background: Corneal neovascularisation (NV) is a refractory condition associated with lipid deposition, scarring and vision loss. Mitomycin C (MMC) intravascular chemoembolisation (MICE) has shown early promise but real-world data remain limited. This study evaluates the efficacy and safety of MICE and MMC intrastromal injection (MIST).Methods: Retrospective case series of patients with corneal NV treated with MICE and/or MIST at Moorfields Eye Hospital between March 2023 and March 2025. NV regression was assessed using (1) ImageJ quantitative analysis, (2) masked independent grading of slit-lamp photographs and (3) surgeon-reported outcomes. Corrected distance visual acuity and complications were recorded.Results: 39 procedures were performed; median follow-up was 12 months. MIST alone was performed in 70% as intravascular cannulation was achieved in only 15%. NV regression was demonstrated in 59% by ImageJ analysis, 71% by independent grading and 81% by surgeon-reported outcomes. Four patients subsequently underwent successful keratoplasty without NV recurrence. Most complications were mild and self-limiting. Two serious complications involving anterior chamber MMC migration occurred in eyes with significant corneal thinning or prior perforation.Conclusions: In the largest cohort reported to date, MICE and MIST represent effective angio-regressive strategies for refractory corneal NV. MIST alone produces meaningful vascular regression, offering a more accessible surgical approach. MMC-based angio-regression appears to be the most effective treatment currently available and may have an important role in stabilising high-risk corneas prior to keratoplasty.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":"990-996"},"PeriodicalIF":4.5,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148052734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aqueous humour outflow improvement after excimer laser trabeculostomy. 准分子激光小梁造口术后房水流出改善。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-20 DOI: 10.1136/bjo-2025-328720

Martin Kallab, Isabella Vieboeck, Parsa Panahi, Kaweh Mansouri, Matthias Bolz, Alex S Huang, Clemens Strohmaier

引用次数: 0

Association of glaucoma and glaucoma treatments with cataract in the UK Biobank: a cross-sectional observational study. 青光眼和青光眼治疗与白内障在英国生物库的关联：一项横断面观察研究。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-19 DOI: 10.1136/bjo-2026-329580

Amy Yen-Chi Chen, Aldric Khoo, Helen Victoria Danesh-Meyer, William Schierding

{"title":"Association of glaucoma and glaucoma treatments with cataract in the UK Biobank: a cross-sectional observational study.","authors":"Amy Yen-Chi Chen, Aldric Khoo, Helen Victoria Danesh-Meyer, William Schierding","doi":"10.1136/bjo-2026-329580","DOIUrl":"https://doi.org/10.1136/bjo-2026-329580","url":null,"abstract":"Background: Glaucoma and cataract are among the leading causes of visual impairment worldwide. Both are prevalent in older adults, but it remains unclear whether their association is independent of age and shared risk factors.Aim: To assess whether glaucoma and its treatments are independently associated with cataract odds using a population-based sample.Methods: Cross-sectional analysis of UK Biobank participants recruited between 2006 and 2010. (Analysis completed in April 2026). Glaucoma and cataract were defined using self-report and International Classification of Diseases-codes from hospital and primary care records. Participants were grouped as no glaucoma, glaucoma with no recorded treatment, topical medications, laser procedures or glaucoma surgery. Multivariable logistic regression estimated cataract odds ratios (OR, 95% CI). Models adjusted for demographic variables, clinical comorbidities and ocular parameters.Results: Among 497 109 adults, glaucoma was associated with higher odds of cataract (OR 3.09, 95% CI 2.73 to 3.49, p<0.01) in fully adjusted models. Odds were higher among those using topical glaucoma treatments (OR 3.14, 95% CI 2.54 to 3.89, p<0.01). Participants who had undergone glaucoma surgery had the highest odds of cataract (OR 12, 95% CI 8.99 to 16.2, p<0.01). Findings were consistent in sensitivity analyses using alternative case definitions.Conclusion: Glaucoma and its management were associated with increased odds of cataract, although the adjusted analysis for the first-line laser subgroup was limited by sample size and cannot be reliably estimated. Longitudinal studies are needed; if confirmed, the results may inform cataract surveillance and timing of operation, relevant in ageing populations.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing physical activity and sleep patterns in glaucoma using wearable devices. 使用可穿戴设备评估青光眼患者的身体活动和睡眠模式。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-18 DOI: 10.1136/bjo-2026-329606

Isaac Bernstein, Sheharbano Jafry, Kuldev Singh, Sophia Y Wang

{"title":"Assessing physical activity and sleep patterns in glaucoma using wearable devices.","authors":"Isaac Bernstein, Sheharbano Jafry, Kuldev Singh, Sophia Y Wang","doi":"10.1136/bjo-2026-329606","DOIUrl":"10.1136/bjo-2026-329606","url":null,"abstract":"Background/aims: Glaucoma has been linked to reduced physical activity and disturbed sleep, but large-scale studies using objective wearable data are scarce. We compared activity and sleep metrics between adults with and without glaucoma using commercial wrist-worn devices.Methods: We conducted a retrospective cross-sectional study within the All of Us Research Program (Registered Tier v8). Participants aged ≥40 years with Fitbit data and with or without a glaucoma diagnosis were included (n=40 743). Daily averages of steps, activity intensity, active calories and time in sleep stages were calculated. Multivariable linear mixed-effects models were adjusted for demographics, body mass index, comorbid sleep disorders and cardiovascular diseases.Results: Of 40 743 participants with complete data, 1245 (3.1%) had glaucoma, contributing a mean of 2.5 years of wearable data. Compared with controls, glaucoma participants had lower daily active calories, fewer lightly and fairly active minutes and fewer steps. They spent less time in bed and asleep, with relatively more light sleep but less deep sleep, REM sleep and restless time. After adjustment, glaucoma remained associated with fewer restless minutes of sleep.Conclusion: In this large wearable-based cohort, glaucoma was independently associated with modest reductions in restless minutes, but not physical activity or other measures of sleep architecture.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adaptive optics imaging in bilateral vitelliform maculopathy. 双侧黄斑黄斑病变的自适应光学成像。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-17 DOI: 10.1136/bjo-2026-329595

Darren Hargreaves, Richard Hagan, Claire Delaney, Jane Gray, Panagiotis Sergouniotis, Karen Mary Hampson

引用次数: 0

Topographic analysis of choroidal thickness in pachychoroid disease using ultra-widefield swept-source optical coherence tomography. 超宽视场扫描源光学相干断层扫描对厚脉络膜疾病脉络膜厚度的地形分析。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-17 DOI: 10.1136/bjo-2026-329844

Alberto Quarta, Ceren Soylu, Rouzbeh Abbasgholizadeh, Shinichiro Chujo, Jianfeng Huang, Mai Alhelaly, Paolo Forte, Swetha Velaga, Muneeswar Nittala, Giulia Corradetti, SriniVas Sadda

{"title":"Topographic analysis of choroidal thickness in pachychoroid disease using ultra-widefield swept-source optical coherence tomography.","authors":"Alberto Quarta, Ceren Soylu, Rouzbeh Abbasgholizadeh, Shinichiro Chujo, Jianfeng Huang, Mai Alhelaly, Paolo Forte, Swetha Velaga, Muneeswar Nittala, Giulia Corradetti, SriniVas Sadda","doi":"10.1136/bjo-2026-329844","DOIUrl":"https://doi.org/10.1136/bjo-2026-329844","url":null,"abstract":"Purpose: To characterise regional and topographic choroidal thickness (CT) profiles using ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) and to compare topographic CT between normal eyes and eyes with pachychoroid disease.Methods: All participants underwent UWF SS-OCT using an approximately 26 mm × 21 mm field of view with fixation centred on the fovea. CT was quantified within concentric rings centred on the optic nerve head and stratified by sector. Linear mixed-effects models were performed separately for each sector, adjusting for age, sex and spherical equivalent (SE). Main outcome measures were regional CT differences between normal and pachychoroid eyes.Results: 60 subjects were included in the study. 37 participants (61.7%) were males and 23 (38.3%) were females. 24 participants (40%) were classified as pachychoroid and 36 (60.0%) as normal. Across all sectors and eccentricities, pachychoroid eyes demonstrated significantly greater CT compared with normal eyes (p<0.001). The largest differences were observed in the temporal sector. In mixed-effects models, pachychoroid status remained a significant independent predictor of increased CT in all sectors (p<0.05) after adjusting for age, SE and sex. SE was independently associated with CT in the inferior, superior and temporal sectors, whereas age and sex were not consistently associated.Conclusions: UWF SS-OCT shows that pachychoroid disease is associated with diffuse, sectorally heterogeneous choroidal thickening extending beyond the fovea. These findings support the concept of pachychoroid disorders as conditions of global choroidal remodelling and highlight the value of regional, distance-based choroidal assessment as a potential imaging biomarker.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic discrepancies in glaucoma: underdiagnosis, overdiagnosis and missed opportunities in a nationwide South Korean population. 青光眼的诊断差异：在韩国全国人口中诊断不足、过度诊断和错失机会。

IF 4.5 2区医学

British Journal of Ophthalmology Pub Date : 2026-08-14 DOI: 10.1136/bjo-2026-329939

Sung Do Cho, Se Hie Park, Young Kook Kim

{"title":"Diagnostic discrepancies in glaucoma: underdiagnosis, overdiagnosis and missed opportunities in a nationwide South Korean population.","authors":"Sung Do Cho, Se Hie Park, Young Kook Kim","doi":"10.1136/bjo-2026-329939","DOIUrl":"https://doi.org/10.1136/bjo-2026-329939","url":null,"abstract":"Background/aims: To investigate glaucoma prevalence and diagnostic discrepancies-undiagnosed glaucoma, missed diagnostic opportunities and false-positive diagnoses-in South Korea and to identify factors contributing to these errors.Methods: This nationwide cross-sectional study used data from the Korea National Health and Nutrition Examination Survey 2019-2021. Participants aged ≥20 years who had gradable ophthalmic examinations were included. Glaucoma was adjudicated by specialists using International Society of Geographical and Epidemiological Ophthalmology criteria. Survey-weighted logistic regression analyses were performed to identify factors associated with undiagnosed glaucoma and missed diagnostic opportunities.Results: The final analytical cohort comprised 18 710 participants. The weighted prevalence of glaucoma was 3.9% (95% CI 3.6% to 4.2%). The awareness rate was only 17.1%, leaving 82.9% (95% CI 80.4% to 85.4%) of cases undiagnosed. Notably, 44.7% (95% CI 41.0% to 48.3%) of undiagnosed cases represented a missed diagnostic opportunity. Multivariable analysis identified high myopia as the strongest predictor of a missed diagnostic opportunity (OR 23.53, 95% CI 5.65 to 98.09, p<0.001), alongside younger age (OR 0.98, p=0.039), rural residence (OR 1.97, p=0.047) and thicker retinal nerve fibre layer (OR 1.09, p<0.001). The lowest household income quartile was associated with undiagnosed glaucoma (OR 1.87, p=0.019).Conclusion: Diagnostic discrepancies present a dual burden: profound underdiagnosis coexists with frequent false-positive diagnosis. High myopia, milder disease phenotype and rural residence are central drivers of missed diagnostic opportunities. Reducing discrepancies will therefore require efforts at both the clinical-professional and health system levels.","PeriodicalId":9313,"journal":{"name":"British Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0