Wanlin Fan,Martine Johanna Jager,Weiwei Dai,Ludwig M Heindl
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引用次数: 0
Abstract
AIMS
Our aim is to develop a deep learning-based system for automatically identifying and classifying benign and malignant tumours of the eyelid to improve diagnostic accuracy and efficiency.
METHODS
The dataset includes photographs of normal eyelids, benign and malignant eyelid tumours and was randomly divided into a training and validation dataset in a ratio of 8:2. We used the training dataset to train eight convolutional neural network models to classify normal eyelids, benign and malignant eyelid tumours. These models included VGG16, ResNet50, Inception-v4, EfficientNet-V2-M and their variants. The validation dataset was used to evaluate and compare the performance of the different deep learning models.
RESULTS
All eight models achieved an average accuracy greater than 0.746 for identifying normal eyelids, benign and malignant eyelid tumours, with an average sensitivity and specificity exceeding 0.790 and 0.866, respectively. The mean area under the receiver operating characteristic curve (AUC) for the eight models was more than 0.904 in correctly identifying normal eyelids, benign and malignant eyelid tumours. The dual-path Inception-v4 network demonstrated the highest performance, with an AUC of 0.930 (95% CI 0.900 to 0.954) and an F1-score of 0.838 (95% CI 0.787 to 0.882).
CONCLUSION
The deep learning-based system shows significant potential in improving the diagnosis of eyelid tumours, providing a reliable and efficient tool for clinical practice. Future work will validate the model with more extensive and diverse datasets and integrate it into clinical workflows for real-time diagnostic support.
目的:我们的目标是开发一个基于深度学习的系统,用于自动识别和分类眼睑的良性和恶性肿瘤,以提高诊断的准确性和效率。方法数据集包括正常眼睑、良性和恶性眼睑肿瘤的照片,按8:2的比例随机分为训练和验证数据集。我们使用训练数据集训练了8个卷积神经网络模型来对正常眼睑、良性和恶性眼睑肿瘤进行分类。这些型号包括VGG16、ResNet50、Inception-v4、EfficientNet-V2-M及其变体。验证数据集用于评估和比较不同深度学习模型的性能。结果8种模型对正常眼睑、良性和恶性眼睑肿瘤的识别准确率均大于0.746,平均敏感性和特异性分别大于0.790和0.866。8种模型在正确识别正常眼睑、良性和恶性眼睑肿瘤时,受试者工作特征曲线下的平均面积(AUC)均大于0.904。双路径Inception-v4网络表现出最高的性能,AUC为0.930 (95% CI 0.900至0.954),f1得分为0.838 (95% CI 0.787至0.882)。结论基于深度学习的眼睑肿瘤诊断系统在提高眼睑肿瘤诊断水平方面具有显著潜力,为临床提供了可靠、高效的工具。未来的工作将用更广泛和多样化的数据集验证该模型,并将其集成到临床工作流程中,以提供实时诊断支持。
期刊介绍:
The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. It also provides major reviews and also publishes manuscripts covering regional issues in a global context.