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Novel Therapeutic Efficacy of Curcumin and Fish Oil (Omega-3 Fatty Acids) on Inhibiting Neuroinflammation and Neuronal Apoptosis via LPS Induction in BV-2 Cells 姜黄素和鱼油(Omega-3脂肪酸)通过LPS诱导抑制BV-2细胞的神经炎症和神经元凋亡的新疗效
American journal of biomedical science & research Pub Date : 2023-06-23 DOI: 10.34297/ajbsr.2023.19.002570
Suhail Rasool
{"title":"Novel Therapeutic Efficacy of Curcumin and Fish Oil (Omega-3 Fatty Acids) on Inhibiting Neuroinflammation and Neuronal Apoptosis via LPS Induction in BV-2 Cells","authors":"Suhail Rasool","doi":"10.34297/ajbsr.2023.19.002570","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002570","url":null,"abstract":"Neurological disorders, such as Parkinson’s Disease and Alzheimer’s Disease, have become more common in recent years, with the number of deaths due to neurological disorders increasing by about 39% since 1990 (GBD 2016 Neurology collaborators, 2019). Neuroinflammation (NI), an inflammatory response within the brain or spinal cord has been shown to accelerate the development of Parkinson’s and Alzheimer’s disease. Conventional pharmaceutical drugs to treat NI can be expensive and promote financial burdens for chronic treatment. The goal of this study was to identify possible natural product alternatives that control NI and stable cell morphology. One viable alternative is curcumin, a chemical compound found in turmeric (Curcuma longa). Another alternative is fish oil, a natural product enriched with omega-3 fatty acids. Pretreatment with curcumin or fish oil significantly attenuated lipopolysaccharide (LPS)-induced cytokine release from acute and chronically treated BV-2 microglial cells and reduced Caspase 3/7 expression in HT-22 neuronal cells.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136084216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solving the Problem of Treating Chronic Bacterial Prostatitis 解决慢性细菌性前列腺炎的治疗问题
American journal of biomedical science & research Pub Date : 2023-06-22 DOI: 10.34297/ajbsr.2023.19.002568
Sergey Roslyak
{"title":"Solving the Problem of Treating Chronic Bacterial Prostatitis","authors":"Sergey Roslyak","doi":"10.34297/ajbsr.2023.19.002568","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002568","url":null,"abstract":"The treatment of chronic prostatitis should be complex and include, if necessary, antibiotic therapy, physiotherapy, diet, anti-inflammatory therapy, herbal medicine, prostate massage, immunoreactive therapy, and so on.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136287405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discovering of Asbestos Fibers and Corn Starch in Talc Material for Baby Powder Samples from Different Markets in Benghazi City 班加西市不同市场婴儿爽身粉样品滑石粉中石棉纤维和玉米淀粉的发现
American journal of biomedical science & research Pub Date : 2023-06-21 DOI: 10.34297/ajbsr.2023.19.002566
Mariam Farag Ambarak
{"title":"Discovering of Asbestos Fibers and Corn Starch in Talc Material for Baby Powder Samples from Different Markets in Benghazi City","authors":"Mariam Farag Ambarak","doi":"10.34297/ajbsr.2023.19.002566","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002566","url":null,"abstract":"This work gives mastery over the asbestos fibers that found their way to talc material in baby powder. There are two kinds of baby powder made up of","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135089965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scientific Discoveries of the 21st Century : Authorised Nobel Award Nominators Take Notice, Please! 21世纪的科学发现:诺贝尔奖提名者请注意!
American journal of biomedical science & research Pub Date : 2023-06-16 DOI: 10.34297/ajbsr.2023.19.002564
Dr Ahmed N M Ghanem
{"title":"Scientific Discoveries of the 21st Century : Authorised Nobel Award Nominators Take Notice, Please!","authors":"Dr Ahmed N M Ghanem","doi":"10.34297/ajbsr.2023.19.002564","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002564","url":null,"abstract":"Introduction and Objective: To report the new scientific discoveries in physics, physiology, and medicine by one author.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135670867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Estimating Three Key Parameters from Measurements in Experiments of Heat Induced Flight 热诱导飞行实验中三个关键参数的估算
American journal of biomedical science & research Pub Date : 2023-06-15 DOI: 10.34297/ajbsr.2023.19.002563
Hong Zhou
{"title":"Estimating Three Key Parameters from Measurements in Experiments of Heat Induced Flight","authors":"Hong Zhou","doi":"10.34297/ajbsr.2023.19.002563","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002563","url":null,"abstract":"We study the problem of heat-induced flight action when a subject is exposed to a millimeter wave beam. There are three key parameters in the model: the nociceptor activation temperature, the subjective threshold for flight initiation, and the human reaction time. We explore mathematical formulations for inferring the three parameters from data measured in exposure tests using the method of limit. We find that the simultaneous inference of the three parameters depends on the experimental design in the sequence of exposure tests. When the beam power density and beam radius of exposure tests span a rectangular region along its two diagonal directions, the three parameters are robustly estimated. Future experiments should consider this pattern of beam power density and beam radius when designing exposure tests. In the case of fluctuating subjective threshold, the medians of three parameters are still reliably estimated when the relative uncertainty in subjective threshold is small or moderate.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135860784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature Loss of the First Permanent Molar. School Solidarity with Panama.2020-2022. 第一恒磨牙过早脱落。学校声援巴拿马:2020-2022年。
American journal of biomedical science & research Pub Date : 2023-06-14 DOI: 10.34297/ajbsr.2023.19.002562
Pedro Rolando López Rodríguez
{"title":"Premature Loss of the First Permanent Molar. School Solidarity with Panama.2020-2022.","authors":"Pedro Rolando López Rodríguez","doi":"10.34297/ajbsr.2023.19.002562","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002562","url":null,"abstract":"The first permanent molar is one of the most important dental structures for the development of a physiological occlusion and an adequate masticatory function, since it defines the development of a practical occlusion, it allows entering the posterior part with a large space, its existence being important for the stability and growth of the occlusion [1].","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136017446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of Anterior Knee Pain After Total Knee Arthroplasty 全膝关节置换术后膝关节前侧疼痛的发生率
American journal of biomedical science & research Pub Date : 2023-06-13 DOI: 10.34297/ajbsr.2023.19.002561
Imran Khan
{"title":"Frequency of Anterior Knee Pain After Total Knee Arthroplasty","authors":"Imran Khan","doi":"10.34297/ajbsr.2023.19.002561","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.19.002561","url":null,"abstract":"Introduction: Anterior Knee Pain (AKP) is one of the most common causes of persistent problems after knee replacement. Total Knee Arthroplasty (TKA) is a surgical procedure in which an artificial joint or prosthesis replaces the damaged knee. A significant proportion of the patients experience AKP after surgery. The pain is described as a retro patellar or peripatellar pain. Patients have trouble standing from sitting position, walking up and down stairs, and riding a bicycle in AKP.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136222891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mini review: Angiogenic Osteogenic Coupled Stents 小回顾:血管生成成骨耦合支架
American journal of biomedical science & research Pub Date : 2023-05-17 DOI: 10.34297/ajbsr.2023.18.002525
Cai Mingxiang Liu Xiangning
{"title":"Mini review: Angiogenic Osteogenic Coupled Stents","authors":"Cai Mingxiang Liu Xiangning","doi":"10.34297/ajbsr.2023.18.002525","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.18.002525","url":null,"abstract":"Bone defect refers to the loss of bone structure caused by trauma, tumor, congenital deformity and other reasons. Bone defect repair is a difficult problem in orthopedics clinic. Bone tissue engineering has brought hope for the repair of bone defects. However, the clinical integration of bone tissue engineering scaffolds is still very low. The major obstacle is the lack of accompanying vascularization of the engineered bone construct, resulting in cell necrosis and bone failure in the area within the implant material. This small review briefly summarizes the novel bone tissue engineering scaffolds with good curative effect in repairing bone defects.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135916547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Pin Site Infection Rate between Schanz Screws And K-Wires in Ilizarov Fixator for Tibial Fracture 胫骨骨折Ilizarov固定架中Schanz螺钉与k -丝钉钉位感染率的比较
American journal of biomedical science & research Pub Date : 2023-05-04 DOI: 10.34297/ajbsr.2023.18.002509
Imran Khan
{"title":"Comparison of Pin Site Infection Rate between Schanz Screws And K-Wires in Ilizarov Fixator for Tibial Fracture","authors":"Imran Khan","doi":"10.34297/ajbsr.2023.18.002509","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.18.002509","url":null,"abstract":"Introduction: Different methods are used to fix external fixator after tibial fracture each having advantages and disadvantages. Objectives: To compare frequency of pin site infection rate between Schanz screws and k-wires in Ilizarov fixator for tibial fracture. Material and Methods: This Randomized control trial Study was conducted in the Department of Orthopedics, Lady Reading Hospital Medical Teaching Institute Peshawar Pakistan from September 2022 till March 2023 on 166 patients aged 20 to 60 years of both gender undergoing Ilizarov fixation after isolated fracture of tibia were enrolled using non-probability consecutive sampling technique, after approval of hospital ethical committee and written informed consent of patients. Patients were randomly divided into two groups using computer generated random sequence number. Patients in group A were stabilized using K-wires and patients in group B were stabilized using K-wire and Schanz screws. Pin site infection was noted in both groups at the end of 12 weeks. Data was entered and analyzed using SPSS 22. Results: In our study 166 patients were enrolled, 83 patients in each group. Mean age was 35.83±7.1 years in group A and 37.7±11.6 years in group B. There were 66.3% males in group A and 69.9% males in group B, females were 33.7% in group and 30.1% in group B. Pin site infection was more common in K-wire group as compared to Schanz group i.e., 18.1%versus 7.2%, p-value 0.036. Conclusion: Schanz screw is associated with decrease pin site infection rate as compared to K-wire in Ilizarov fixator for tibial fracture.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136375128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emphysematous Gastritis 肺气肿的胃炎
American journal of biomedical science & research Pub Date : 2023-04-19 DOI: 10.34297/ajbsr.2023.18.002492
Luis Enrique Nunez Moscoso
{"title":"Emphysematous Gastritis","authors":"Luis Enrique Nunez Moscoso","doi":"10.34297/ajbsr.2023.18.002492","DOIUrl":"https://doi.org/10.34297/ajbsr.2023.18.002492","url":null,"abstract":"","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135861945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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