Mini review: Angiogenic Osteogenic Coupled Stents

Abstract

Bone defect refers to the loss of bone structure caused by trauma, tumor, congenital deformity and other reasons. Bone defect repair is a difficult problem in orthopedics clinic. Bone tissue engineering has brought hope for the repair of bone defects. However, the clinical integration of bone tissue engineering scaffolds is still very low. The major obstacle is the lack of accompanying vascularization of the engineered bone construct, resulting in cell necrosis and bone failure in the area within the implant material. This small review briefly summarizes the novel bone tissue engineering scaffolds with good curative effect in repairing bone defects.