Advancements in journal of urology and nephrology最新文献_第2页

De Novo Minimal Changes Disease Associated to Inoculation with Adenovirus Vector Vaccine (Sputnik V) 与接种腺病毒载体疫苗(Sputnik V)相关的新生微小变化疾病

Advancements in journal of urology and nephrology Pub Date : 2022-01-05 DOI: 10.33140/ajun.04.01.01

{"title":"De Novo Minimal Changes Disease Associated to Inoculation with Adenovirus Vector Vaccine (Sputnik V)","authors":"","doi":"10.33140/ajun.04.01.01","DOIUrl":"https://doi.org/10.33140/ajun.04.01.01","url":null,"abstract":"Due to the pandemic caused by the virus SARS-CoV-2, multiple therapeutic and preventive strategies have been developed in order to avoid its propagation. Vaccines have been proved to be the most efficient means to control the spread of COVID 19, which has prevented both massive admissions of critical patients to intensive care units and the collapse of the health system from happening. To the present day there are different tested vaccine platforms with adenovirus vectors, inactivated vaccines and nucleic acid vaccines, among others [1]. As the vaccination process moved forward around the globe, there has been a number of publications reporting on adverse renal events, which included case reports on Secondary Nephrotic Syndome derived from Minimal Changes Disease (MCD) after the application of both, nucleic acid (RNAm) and adenovirus vector vaccines. Case presentation: male patient presented with nephrotic syndrome without microhematuria and with renal dysfunction after the application of the second dose of SPUTNIK V vaccine, which is why a renal biopsy was carried out. Such biopsy reported it was a case of MCD, which had a complete remission after six weeks of oral corticosteroids.","PeriodicalId":93064,"journal":{"name":"Advancements in journal of urology and nephrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44885900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methylprednisolone Protects Severe Acute Pancreatitis And Pancreatitis-Associated Acute Lung Injury in Mice By Inhibiting NLRP3 Inflammasome Through NF-κB 甲基泼尼松通过NF-κB抑制NLRP3炎症小体保护小鼠重症急性胰腺炎和胰腺炎相关急性肺损伤

Advancements in journal of urology and nephrology Pub Date : 2022-01-05 DOI: 10.33140/ajun.04.01.03

{"title":"Methylprednisolone Protects Severe Acute Pancreatitis And Pancreatitis-Associated Acute Lung Injury in Mice By Inhibiting NLRP3 Inflammasome Through NF-κB","authors":"","doi":"10.33140/ajun.04.01.03","DOIUrl":"https://doi.org/10.33140/ajun.04.01.03","url":null,"abstract":"In serve acute pancreatitis (SAP), the rapid production and releasing of inflammatory cytokines can cause local and systemic excessive inflammation, especially pancreatitis-associated acute lung injury (P-ALI). Methylprednisolone (MP) is a synthetic corticosteroid with potent anti-inflammatory and antioxidant properties used as therapy for a variety of diseases. In this study, we found MP, used in the early phase of SAP, decreased the levels of IL-1β and TNF-α in serum and peritoneal lavage fluids (PLF), reduced the level of serum amylase and the expression of MPO in lung tissue, attenuated the pathological injury of the pancreas and lungs in a dosedependent manner. The expression of NLRP3 and IL-1β in pancreas and lungs was down regulated significantly depending on the MP concentration. In vitro, MP reduced the levels of IL-1β and TNF-α by down regulating the expression of NLRP3, IL-1β and p-NF-κB in isolated peritoneal macrophages. Taken together, MP can attenuate the injury of pancreas and lungs, and the inflammatory response in SAP mice by down regulating the activation of NF-κB and the NLRP3 inflammasome.","PeriodicalId":93064,"journal":{"name":"Advancements in journal of urology and nephrology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41999005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Medical (bedside) Peritoneal Dialysis catheter insertion in Intensive Therapy Unit setting, an overlooked Renal Replacement Therapy option, A Case Study 急性医学（床边）腹膜透析导管在强化治疗室的插入，一种被忽视的肾脏替代治疗选择，一个案例研究

Advancements in journal of urology and nephrology Pub Date : 2021-03-08 DOI: 10.33140/ajun.03.01.03

M. Fawzy

引用次数: 0

Acute Renal Failure Induced by Madder Madder致急性肾衰竭

Advancements in journal of urology and nephrology Pub Date : 2021-03-08 DOI: 10.33140/ajun.03.01.01

引用次数: 2

A Case for Worldwide Mass Immunization with MMR to Limit Deaths from COVID-19 全球大规模接种MMR疫苗以限制COVID-19死亡的案例

Advancements in journal of urology and nephrology Pub Date : 2021-03-08 DOI: 10.33140/ajun.03.01.02

引用次数: 0

Micropercutaneous Laser Lithotripsy: How to Improve Stone Free Rate 微创激光碎石术：如何提高结石清除率

Advancements in journal of urology and nephrology Pub Date : 2020-10-09 DOI: 10.33140/ajun.02.04.02

{"title":"Micropercutaneous Laser Lithotripsy: How to Improve Stone Free Rate","authors":"","doi":"10.33140/ajun.02.04.02","DOIUrl":"https://doi.org/10.33140/ajun.02.04.02","url":null,"abstract":"Introduction: Micropercutaneous Nephrolithotomy is a novel technique with the creation of a 4.85-8F working channel. The advantage of micro-PCNL is the possibility of kidney puncture under direct endoscopic control. Materials and Methods: 99 patients aged 47,3 ± 16.9 years were included in the study. 78 patients had isolated kidney stones (78.8%). The stone size ranged from 8 to 38 mm (13.9 ± 5.4 mm). Group A included stones smaller than 15 mm (57 patients, 57,6%) and Group B included stones larger than 15 mm (42 patients, 42,4%). A 4.85 F percutaneous sheath was used in 38 (38,4%) patients, 8 F sheath was used in 61 (61,6%) patients. A holmium laser for lithotripsy was used in 46.5% cases, the thulium fiber laser in 53.5%. Results: The average surgery time was 39,9 ± 13.7 min (from 13 to 75 min). A stone-free rate (SFR) for patients of both groups was 88.8%. A Double-J stent was placed in 39 (39.4%) patients. In one case conversion to the mini-PCNL was done. In four cases (4%) retrograde stone manipulations were performed through ureteral access sheath. 5 (5.1%) patients required the second micro-PCNL tract. 3 (3%) patients required stenting postoperatively. In 7.1% of cases the episode of acute pyelonephritis developed. In 7 cases (7,1%), Extracorporeal Shock Wave Lithotripsy was required due to residual stones. Conclusions: We recommend using the laser micro-PCNL for the category of patients with severe comorbidities, including coagulopathy. The micro-PCNL could be safely performed in patients with kidney stones larger than 1.5 cm.","PeriodicalId":93064,"journal":{"name":"Advancements in journal of urology and nephrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47365083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Prevalence of Grade III Varicocele and Undescended Testis in Turkish Adolescent Males 土耳其青少年男性III级精索静脉曲张和隐睾的患病率

Advancements in journal of urology and nephrology Pub Date : 2020-10-09 DOI: 10.33140/ajun.02.04.03

{"title":"The Prevalence of Grade III Varicocele and Undescended Testis in Turkish Adolescent Males","authors":"","doi":"10.33140/ajun.02.04.03","DOIUrl":"https://doi.org/10.33140/ajun.02.04.03","url":null,"abstract":"Objective: To determine the grade III varicocele and undescended testis (UDT) prevalence, testicular atrophy rate, and treatment rate in adolescent boys aged 13-15 in the Turkish population. Methods: Healthy boys who were candidates for military high schools were evaluated between June and July 2015. Patients with undescended testis or grade III varicocele were recorded. Also, the presence of testicular atrophy and history of previous surgeries were recorded. The prevalence of grade III varicocele and UDT, testicular atrophy rate and treatment data were assessed. Results: Grade III varicocele was detected in 627 (6.48%) of 9669 boys. Testicular atrophy due to grade III varicocele was detected in 213 (33.97%) of the cases. Patients who did not undergo varicocelectomy are more likely to have testicular atrophy than patients who underwent varicocelectomy (35.37% vs 19.64%, p=0.018). The UDT was detected in 96 (0.99%) candidates. Of those, 76 (79.16%) candidates had unilateral, and 20 (20.83%) candidates had bilateral UDT. 84 (87.50%) candidates underwent at least one surgery for the management of UDT and 12.5% of the candidates (n=12) were not aware of their diseases. Conclusion: This study shows us the prevalence of grade III varicocele in our population. Varicocele is a progressive disease that can cause fertility and testicular atrophy increases with the puberty.","PeriodicalId":93064,"journal":{"name":"Advancements in journal of urology and nephrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45491507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Safe Use of Rituximab In The Management of ANCA-Associated Vasculitis In A Patient With Suspicious Renal Cyst – A Case Report 利妥昔单抗在治疗可疑肾囊肿患者ANCA相关血管炎中的安全应用——一例报告

Advancements in journal of urology and nephrology Pub Date : 2020-10-09 DOI: 10.33140/ajun.02.04.01

引用次数: 0

APOL 1 and kidney disease APOL 1与肾脏疾病

Advancements in journal of urology and nephrology Pub Date : 2020-07-03 DOI: 10.33140/ajun.02.03.04

引用次数: 1

Surgical Complications RevealingNephrotic Syndrome Of Children At ’’Hopital Saint Jean De Dieu De Tanguieta’’ (Benin) 贝宁圣让·德·德·丹吉埃塔医院儿童肾病综合征的外科并发症分析

Advancements in journal of urology and nephrology Pub Date : 2020-07-03 DOI: 10.33140/ajun.02.03.05

{"title":"Surgical Complications RevealingNephrotic Syndrome Of Children At ’’Hopital Saint Jean De Dieu De Tanguieta’’ (Benin)","authors":"","doi":"10.33140/ajun.02.03.05","DOIUrl":"https://doi.org/10.33140/ajun.02.03.05","url":null,"abstract":"Background:Thromboembolic and infectious complications of nephrotic syndrome are powerfuland canbefunctional or life threatening. Surgical complications are rare, hence the interest of our work which aimed to study the therapeutic and evolutionary clinical aspects of the surgical complications of the children’s nephrotic syndrome at ’’Hopital Saint Jean De Dieu De Tanguieta’’ (Benin). Methods: This was a prospective case study of children with complicatednephrotic syndrome followed at ‘’Hopital Saint Jean De Dieu De Tanguieta’’ (Benin) fromOctober 2016 to December 2018. Results: We reported two cases, all male. Before surgical complications the symptoms were dominated by an oedema syndrome lasting for each of them on averageeightmonths. Surgical complications thatrevealednephrotic syndrome were a spontaneous amputation of the right foot due to arterialthrombosis in a seven-year-old boy and a necrotizingfasciitis of the left foot in a 10-year-old child.The nephrotic syndrome wasidiopathic and the cares werebothsurgical and medical. Nephrotic syndrome wascorticosensitivewith a goodevolution in five months. Conclusion: These two cases teach that any childhoodoedema syndrome must bequicklyexplored for appropriated management to avoidtheseserious complications and aftereffects.","PeriodicalId":93064,"journal":{"name":"Advancements in journal of urology and nephrology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45224886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0