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Asbestos and benign pleural diseases: a narrative review. 石棉与良性胸膜疾病：叙述性回顾。
IF 2.3
Breathe Pub Date : 2025-05-13 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0236-2024
Lucía Ferreiro, María E Toubes, Nuria Rodríguez-Núñez, Luis Valdés
{"title":"Asbestos and benign pleural diseases: a narrative review.","authors":"Lucía Ferreiro, María E Toubes, Nuria Rodríguez-Núñez, Luis Valdés","doi":"10.1183/20734735.0236-2024","DOIUrl":"10.1183/20734735.0236-2024","url":null,"abstract":"<p><p>The term \"asbestos\" is used to refer to a group of silicate minerals that often break down into fibres and whose inhalation over time can cause a number of diseases, especially pleuropulmonary diseases. While the most serious complications are malignant diseases, inhalation of these fibres can also cause benign pleural diseases such as round atelectasis, pleural plaques, diffuse pleural thickening and non-malignant asbestos pleural effusion. Although asbestos is banned in most developed countries (in the European Union, since 2002), it is still used in developing countries. Despite these restrictions, the prevalence of diseases due to inhalation remains high due to the long latency period between the onset of exposure and the onset of disease. In this paper we review benign pleural diseases induced by asbestos exposure, update the diagnostic criteria for these disorders, and describe the approaches suggested so far to differentiate them from malignant pleural diseases.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240236"},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of forced oscillation technique in children with restrictive physiology. 强迫振荡技术在限制性生理患儿中的应用。
IF 2.3
Breathe Pub Date : 2025-05-13 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0106-2024
Andre Gie, Ruan Swanepoel, Marieke M van der Zalm, Pierre Goussard
{"title":"The use of forced oscillation technique in children with restrictive physiology.","authors":"Andre Gie, Ruan Swanepoel, Marieke M van der Zalm, Pierre Goussard","doi":"10.1183/20734735.0106-2024","DOIUrl":"10.1183/20734735.0106-2024","url":null,"abstract":"<p><p><b>The forced oscillation technique (FOT) may not identify lung function abnormalities in children with restrictive physiology. FOT findings correlate poorly with spirometry and plethysmography testing in children with diffuse parenchymal lung disease.</b> https://bit.ly/4h4liIh.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240106"},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interstitial lung diseases. 肺间质性疾病。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0169-2025
Imran Sulaiman
{"title":"Interstitial lung diseases.","authors":"Imran Sulaiman","doi":"10.1183/20734735.0169-2025","DOIUrl":"https://doi.org/10.1183/20734735.0169-2025","url":null,"abstract":"<p><p><b>This issue of <i>Breathe</i> focuses on interstitial lung diseases</b> https://bit.ly/4lhll67.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"250169"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The lung microbiome in interstitial lung disease. 肺间质性疾病的肺微生物组。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0167-2024
Sheridan G Mikhail, David N O'Dwyer
{"title":"The lung microbiome in interstitial lung disease.","authors":"Sheridan G Mikhail, David N O'Dwyer","doi":"10.1183/20734735.0167-2024","DOIUrl":"https://doi.org/10.1183/20734735.0167-2024","url":null,"abstract":"<p><p>Interstitial lung disease (ILD) is a heterogeneous chronic form of lung disease. The pathogenesis of ILD is poorly understood and a common form of ILD, idiopathic pulmonary fibrosis (IPF) is associated with poor prognosis. There is evidence for substantial dysregulated immune responses in ILD. The microbiome is a key regulator of the immune response, and the lung microbiome correlates with alveolar immunity and clinical outcomes in ILD. Most observational lung microbiome studies have been conducted in patients with IPF. A consistent observation in these studies is that the bacterial burden of the lung is elevated in patients with IPF and predicts mortality. However, our understanding of the mechanism is incomplete and our understanding of the role of the lung microbiome in other forms of ILD is limited. The microbiomes of the oropharynx and gut may have implications for the lung microbiome and pulmonary immunity in ILD but require substantial further research. Here, we discuss the studies supporting a role for the lung microbiome in the pathogenesis of IPF, and briefly describe the putative role of the oral-lung axis and the gut-lung axis in ILD.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240167"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of mechanical ventilation in interstitial lung disease. 机械通气在间质性肺疾病中的应用。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0172-2024
Timothy J Nolan, Isabel Dwyer, Pierce Geoghegan
{"title":"The use of mechanical ventilation in interstitial lung disease.","authors":"Timothy J Nolan, Isabel Dwyer, Pierce Geoghegan","doi":"10.1183/20734735.0172-2024","DOIUrl":"https://doi.org/10.1183/20734735.0172-2024","url":null,"abstract":"<p><p>This review explores the challenges and strategies for managing mechanical ventilation in interstitial lung disease (ILD), particularly during acute exacerbations. It highlights the unique physiological barriers posed by fibrotic, non-compliant lungs, discusses evidence-based approaches to noninvasive and invasive ventilation, and emphasises the importance of balancing life-sustaining treatments with palliative care. This review aims to provide practical insights into optimising respiratory support for ILD patients while aligning treatment goals with patient prognosis and preferences.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240172"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of pulmonary and cutaneous sarcoidosis. 肺及皮肤结节病1例。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0228-2024
Eimear Foley, Ahmad Basirat, Ankit Yadav, Shane O'Brien, Patrick D Mitchell, Seamas C Donnelly
{"title":"A case of pulmonary and cutaneous sarcoidosis.","authors":"Eimear Foley, Ahmad Basirat, Ankit Yadav, Shane O'Brien, Patrick D Mitchell, Seamas C Donnelly","doi":"10.1183/20734735.0228-2024","DOIUrl":"https://doi.org/10.1183/20734735.0228-2024","url":null,"abstract":"<p><p><b>A case demonstrating refractory cutaneous and pulmonary sarcoidosis, with classic clinical, spirometry and radiological features, despite OCS and low-dose HCQ treatment that responded clinically and functionally to the addition of a TNF inhibitor</b> https://bit.ly/4h8Gix1.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240228"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A non-resolving cough in a 41-year-old woman: a case of familial pulmonary fibrosis. 41岁妇女止咳不愈：家族性肺纤维化1例。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0258-2024
Aoife Carolan, Mari Ozaki, Wan Lin Ng, John Ryan, Michael W O'Reilly, Ruth Dunne, Aurelie Fabre, Nadia Nathan, Caroline Kannengiesser, Raphael Borie, Killian Hurley
{"title":"A non-resolving cough in a 41-year-old woman: a case of familial pulmonary fibrosis.","authors":"Aoife Carolan, Mari Ozaki, Wan Lin Ng, John Ryan, Michael W O'Reilly, Ruth Dunne, Aurelie Fabre, Nadia Nathan, Caroline Kannengiesser, Raphael Borie, Killian Hurley","doi":"10.1183/20734735.0258-2024","DOIUrl":"https://doi.org/10.1183/20734735.0258-2024","url":null,"abstract":"<p><p><b>Identification of cases of familial pulmonary fibrosis is important with the risk of a monogenic cause. Patients appear to be younger and may have a more progressive disease. Consideration for antifibrotics and early transplant referral should be made.</b> https://bit.ly/42jJ3aO.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240258"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent unilateral pleural effusion in a 63-year-old man: the answer lies in the mediastinum. 63岁男性复发性单侧胸腔积液：答案在于纵隔。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0237-2024
Lorenzo Carriera, Guido Levi, Federico Cremonesi, Giulia Gri, Venere Piluso, Maroon Salameh, Iacopo Ghini, Luisa Lorenzi, Gianpietro Marchetti, Damiano Bottone
{"title":"Recurrent unilateral pleural effusion in a 63-year-old man: the answer lies in the mediastinum.","authors":"Lorenzo Carriera, Guido Levi, Federico Cremonesi, Giulia Gri, Venere Piluso, Maroon Salameh, Iacopo Ghini, Luisa Lorenzi, Gianpietro Marchetti, Damiano Bottone","doi":"10.1183/20734735.0237-2024","DOIUrl":"https://doi.org/10.1183/20734735.0237-2024","url":null,"abstract":"<p><p><b>Benign vascular masses in the mediastinum, such as haemangiomas, should be considered in the differential diagnosis of unexplained pleural effusions</b> https://bit.ly/4fOjtO1.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240237"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cough in idiopathic pulmonary fibrosis: what is new. 特发性肺纤维化的咳嗽：什么是新的。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0176-2024
Marta Alexandra Carvalho da Silva, Rui Miguel Mouro de Santos Rolo, Maria Joana Pereira Catarata, Eva Filipa de Sousa Antunes Dias Padrão
{"title":"Cough in idiopathic pulmonary fibrosis: what is new.","authors":"Marta Alexandra Carvalho da Silva, Rui Miguel Mouro de Santos Rolo, Maria Joana Pereira Catarata, Eva Filipa de Sousa Antunes Dias Padrão","doi":"10.1183/20734735.0176-2024","DOIUrl":"https://doi.org/10.1183/20734735.0176-2024","url":null,"abstract":"<p><p>Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal interstitial fibrosing disease and, despite some well-known risk factors, its cause is still unknown. Cough is experienced by most patients and is commonly chronic and refractory, having a significant impact on quality of life. Its aetiology is complex, combining factors related to interstitial lung disease (ILD) such as an increased sensitivity of cough-sensitive nerves, structural lung changes and inflammation, genetic factors, several comorbidities and medication-adverse effects. Despite the therapeutic advancements in IPF over the past decade with the introduction of antifibrotic drugs that slow disease progression, effective treatment options for cough in IPF remain unavailable. Cough management often relies on empirical approaches based on studies involving chronic cough patients of unspecified causes and ILD physicians' personal experiences. Different classes of medications have been tried over time and, more recently, the focus has turned to neuromodulators and opioids, but several studies have shown suboptimal efficacy in cough. On the other hand, these drugs are associated with significant physical, psychological and economic burdens. However, the future brings us hope to the extent that most current ongoing clinical trials are using new molecules and some have demonstrated promising antitussive effects. This review aims to provide a practical guide to understanding and managing cough in IPF patients, presenting pharmacological and non-pharmacological approaches over time, as well as those treatments that are currently being investigated in clinical settings.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240176"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracic ultrasound in interstitial lung disease. 肺间质性疾病的胸部超声诊断。
IF 2.3
Breathe Pub Date : 2025-04-17 eCollection Date: 2025-04-01 DOI: 10.1183/20734735.0170-2024
Dishant Joy Shah, Anthony Esposito, Areen Pitaktong, Harald Sauthoff
{"title":"Thoracic ultrasound in interstitial lung disease.","authors":"Dishant Joy Shah, Anthony Esposito, Areen Pitaktong, Harald Sauthoff","doi":"10.1183/20734735.0170-2024","DOIUrl":"https://doi.org/10.1183/20734735.0170-2024","url":null,"abstract":"<p><p><b>B-lines and pleural line thickening on LUS are sensitive but nonspecific signs of ILD. LUS aids in early detection and monitoring, but HRCT and PFT remain the gold standards. Limitations include operator dependence and lack of standardised protocols.</b> https://bit.ly/41vUQSn.</p>","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 2","pages":"240170"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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