Journal of pancreatology最新文献_第5页

Pancreatic tuberculosis misdiagnosed for surgical treatment: Clinical analysis 胰腺结核误诊手术治疗:临床分析

Journal of pancreatology Pub Date : 2023-08-29 DOI: 10.1097/jp9.0000000000000142

Bin Zhou, Zusen Wang, Caiyan Yu, Shuxiang Jin, Tengfei Qu

引用次数: 0

Chinese Expert Consensus on Multidisciplinary Diagnosis and Treatment of Pancreatic Neuroendocrine Liver Metastases 胰腺神经内分泌肝转移多学科诊治中国专家共识

Journal of pancreatology Pub Date : 2023-08-24 DOI: 10.1097/jp9.0000000000000141

Y. Chi, Liming Jiang, S. Shi, S. He, C. Bai, D. Cao, Qichen Chen, Xiao Chen, Yiqiao Deng, S. Du, Zhen Huang, Li Huo, Yuan Ji, Jie Li, W. Lou, Jie Luo, Xueying Shi, Lijie Song, Bei Sun, H. Tan, Feng Wang, Xuan Wang, Zhewen Wei, Wenming Wu, D. Xiu, Jianming Xu, Huadan Xue, Yi Yang, Fei Yin, Jiangyuan Yu, C. Yuan, Ye‐fan Zhang, Weixun Zhou, Dongbing Zhao, Hong Zhao

{"title":"Chinese Expert Consensus on Multidisciplinary Diagnosis and Treatment of Pancreatic Neuroendocrine Liver Metastases","authors":"Y. Chi, Liming Jiang, S. Shi, S. He, C. Bai, D. Cao, Qichen Chen, Xiao Chen, Yiqiao Deng, S. Du, Zhen Huang, Li Huo, Yuan Ji, Jie Li, W. Lou, Jie Luo, Xueying Shi, Lijie Song, Bei Sun, H. Tan, Feng Wang, Xuan Wang, Zhewen Wei, Wenming Wu, D. Xiu, Jianming Xu, Huadan Xue, Yi Yang, Fei Yin, Jiangyuan Yu, C. Yuan, Ye‐fan Zhang, Weixun Zhou, Dongbing Zhao, Hong Zhao","doi":"10.1097/jp9.0000000000000141","DOIUrl":"https://doi.org/10.1097/jp9.0000000000000141","url":null,"abstract":"Many management strategies are available for pancreatic neuroendocrine neoplasms with liver metastases. However, a lack of biological, molecular, and genomic information and an absence of data from rigorous trials limit the validity of these strategies. This review presents the viewpoints from an international conference consisting of several expert working groups. The working groups reviewed a series of questions of particular interest to clinicians taking care of patients with pancreatic neuroendocrine neoplasms with liver metastases by reviewing the existing management strategies and literature, evaluating the evidence on which management decisions were based, developing internationally acceptable recommendations for clinical practice, and making recommendations for clinical and research endeavors. The review for each question will be followed by recommendations from the panel.","PeriodicalId":92925,"journal":{"name":"Journal of pancreatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41507031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pancreatic Cancer Related Pain: Mechanism and Management 胰腺癌相关疼痛:机制和管理

Journal of pancreatology Pub Date : 2023-08-17 DOI: 10.1097/jp9.0000000000000140

Meijing Wu, A-Fang Zhu, Le Shen

引用次数: 0

Consensus of clinical diagnosis and treatment for non-functional pancreatic neuroendocrine neoplasms with diameter less than 2cm 直径小于2cm的非功能性胰腺神经内分泌肿瘤的临床诊治共识

Journal of pancreatology Pub Date : 2023-08-10 DOI: 10.1097/jp9.0000000000000139

Wenming Wu, S. Cai, Rufu Chen, D. Fu, C. Ge, C. Hao, J. Hao, Heguang Huang, Z. Jian, G. Jin, Fei Li, Hai-ming Li, Sheng-ping Li, Weiqin Li, Yixiong Li, T. Liang, Xu-Bao Liu, W. Lou, Y. Miao, Yiping Mou, C. Peng, R. Qin, C. Shao, B. Sun, Guang-xi Tan, Huaizhi Wang, Lei Wang, Wei Wang, Weilin Wang, Junmin Wei, Heshui Wu, Zheng-Ren Wu, Chang-qing Yan, Yinmo Yang, Xiaoyu Yin, Xianjun Yu, C. Yuan, Yupei Zhao

引用次数: 0

Comparison of Outcomes with Stapler Versus Hand-Sewn Closure of the Pancreatic Stump following Minimally Invasive Distal Pancreatectomy: A Retrospective Cohort Study 微创远端胰腺切除术后吻合吻合钉与手缝合胰腺残端的疗效比较：一项回顾性队列研究

Journal of pancreatology Pub Date : 2023-08-10 DOI: 10.1097/jp9.0000000000000138

Tao Qian, Kaiquan Huang, Wenqing Chen, X. Bai, Shunliang Gao, Yan Shen, M. Zhang, Jian Wu, Jun Yu, T. Ma, T. Liang

{"title":"Comparison of Outcomes with Stapler Versus Hand-Sewn Closure of the Pancreatic Stump following Minimally Invasive Distal Pancreatectomy: A Retrospective Cohort Study","authors":"Tao Qian, Kaiquan Huang, Wenqing Chen, X. Bai, Shunliang Gao, Yan Shen, M. Zhang, Jian Wu, Jun Yu, T. Ma, T. Liang","doi":"10.1097/jp9.0000000000000138","DOIUrl":"https://doi.org/10.1097/jp9.0000000000000138","url":null,"abstract":"\u0000 \u0000 Pancreatic fistula after distal pancreatectomy is a common and potentially lethal complication. The optimal closure method for the pancreatic remnant during minimally invasive distal pancreatectomy (MDP) remains unclear.\u0000 \u0000 \u0000 \u0000 Data of consecutive patients who underwent MDP in our institution between July 2018 and June 2021 were collected. The outcomes of MDP with stapler and hand-sewn closure were compared. The primary outcome was clinically relevant postoperative pancreatic fistula (CR-POPF) per the International Study Group of Pancreatic Surgery definition.\u0000 \u0000 \u0000 \u0000 Of the 384 patients (stapler closure, 339; hand-sewn closure, 45) enrolled, 249 developed CR-POPF (grades B and C: 242 and 7 patients, respectively). The rates of grade B and grade C POPF in the stapler group were similar to the corresponding rates in the hand-sewn group (64.6% and 1.5% vs. 51.1% and 4.4%, P = 0.078 and P = 0.223, respectively). No differences between the stapler and hand-sewn groups were observed regarding the median operation time (207 min vs. 222 min, P = 0.139), incidence of major complications (16.5% vs. 20.0%, P = 0.559), and mortality (0.2% vs. 0%, P = 1.000). The independent risk factors of CR-POPF were abdominal abscess, prolonged operation time, and transection site (P = 0.004, 0.006, and 0.001, respectively).\u0000 \u0000 \u0000 \u0000 The incidence and severity of CR-POPF by stapler closure of the pancreatic stump were comparable to those associated with hand-sewn closure in MDP in this retrospective cohort. Randomized controlled trials are needed to verify this finding.\u0000","PeriodicalId":92925,"journal":{"name":"Journal of pancreatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47631886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PANCREATIC BIOMARKERS: ROLE IN DIABETES MELLITUS 胰腺生物标志物在糖尿病中的作用

Journal of pancreatology Pub Date : 2023-08-10 DOI: 10.1097/jp9.0000000000000137

Sana Rafaqat, Ramsha Hafeez, Rida Mairaj, Abeer Saleem, Saira Rafaqat

{"title":"PANCREATIC BIOMARKERS: ROLE IN DIABETES MELLITUS","authors":"Sana Rafaqat, Ramsha Hafeez, Rida Mairaj, Abeer Saleem, Saira Rafaqat","doi":"10.1097/jp9.0000000000000137","DOIUrl":"https://doi.org/10.1097/jp9.0000000000000137","url":null,"abstract":"Diabetes mellitus refers to a group of diseases that cause high blood sugar levels. The most common type is type 2 diabetes, which is caused by insulin resistance and inadequate insulin production. However, diabetes can also result from conditions affecting the exocrine pancreas. Both type 1 and type 2 diabetes patients may experience changes in their pancreatic exocrine function, leading to reduced levels of fecal elastase-1 in many cases. This review paper focuses on the role of specific pancreatic biomarkers in diabetes mellitus, including cholecystokinin, trypsin, chymotrypsin, carboxypeptidase, amylase, lipase, secretin, elastase-1, and retinol-binding protein 4 about recent advances and discoveries, significant gaps in the literature, current debates, and potential directions for future research related to these biomarkers about diabetes mellitus. This review article discusses various biomarkers related to pancreatic exocrine and endocrine function and their implications in diabetes. It suggests that gut cholecystokinin may play a role in lowering glucose synthesis through a neural network and resistance to it could contribute to hyperglycemia in diabetic patients. It also discusses the use of various markers such as serum trypsin concentration, amylase and lipase levels, pancreatic elastase levels, and fasting secretin levels to assess pancreatic exocrine function. Additionally, the article explores the role of carboxypeptidase E in the endocrine and neurological systems and its association with disorders. Moreover, it also highlights the involvement of retinol-binding protein 4 in the development of type 2 diabetes and insulin resistance.","PeriodicalId":92925,"journal":{"name":"Journal of pancreatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46022594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological and Non-pharmacological Prophylaxis in the Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis; A Narrative Review 内镜下逆行胰胆管造影后胰腺炎的药物和非药物预防叙述性回顾

Journal of pancreatology Pub Date : 2023-08-04 DOI: 10.1097/jp9.0000000000000136

Amina Ehsan

{"title":"Pharmacological and Non-pharmacological Prophylaxis in the Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis; A Narrative Review","authors":"Amina Ehsan","doi":"10.1097/jp9.0000000000000136","DOIUrl":"https://doi.org/10.1097/jp9.0000000000000136","url":null,"abstract":"Endoscopic retrograde cholangiopancreatography is a diagnostic and therapeutic procedure for various gastrointestinal problems. Pancreatitis is a severe complication of the procedure. The main objective of this study was to address if post-ERCP pancreatitis can be prevented and what are the various pharmacological and non-pharmacological options along with their efficacy. Keywords ‘post-ERCP’ and ‘pancreatitis’ were used to search articles in Pubmed. Randomized controlled trials on patients undergoing ERCP due to any disease using pharmacological or non-pharmacological intervention published in the last seven years were included. Observational studies, descriptive studies, reviews, and studies with no full access were excluded. The primary outcome in the trials was a frequency of post-ERCP pancreatitis. NSAIDs were the most effective drugs in reducing the incidence of pancreatitis. The preferred route was rectal. After NSAIDs, intravenous hydration and sublingual nitrate showed promising outcomes, especially when combined with rectal NSAIDs. Other drugs like magnesium sulfate and nafamostat mesilate did reduce the incidence, but the results were not statistically significant. Epinephrine spray on duodenal papilla showed no benefits and instead had a risk of increasing the incidence. Stent placement also reduced the incidence of pancreatitis. In conclusion, rectal NSAIDs alone or combined with IV hydration and sublingual nitrate significantly reduced the incidence of pancreatitis, and stent placement was comparable to pharmacological interventions. Thus, regular use of pharmacological interventions before the procedure can help to reduce the incidence of this grave complication.","PeriodicalId":92925,"journal":{"name":"Journal of pancreatology","volume":"260 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136118872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellular crosstalk of regulatory T cells in pancreatic ductal adenocarcinoma 胰腺导管腺癌中调节性T细胞的细胞串扰

Journal of pancreatology Pub Date : 2023-07-14 DOI: 10.1097/jp9.0000000000000135

Xuqing Shi, Hangqi Liu, Zhiyong Liang

引用次数: 0

Isolated myeloid sarcoma of the pancreas: A case report 胰腺分离性髓系肉瘤1例报告

Journal of pancreatology Pub Date : 2023-06-29 DOI: 10.1097/jp9.0000000000000134

Lei Jiang, Y. Miao, Jishu Wei

引用次数: 0

Pancreatic Adenocarcinoma and Ageing: Understanding the Menace for Better Management 胰腺腺癌与衰老：了解威胁以便更好地治疗

Journal of pancreatology Pub Date : 2023-06-26 DOI: 10.1097/jp9.0000000000000133

Tianxing Zhou, Jingrui Yan, J. Hao, Jun Yu

引用次数: 0