International journal of physiology最新文献_第3页

Effect of Laurusnobilis extract and Atorvastatin on Liver and Kidney function of Hyperlipidemia Male Rats 月桂提取物和阿托伐他汀对高脂血症雄性大鼠肝肾功能的影响

International journal of physiology Pub Date : 2022-01-01 DOI: 10.37506/ijop.v10i1.3208

Faraj Hato

{"title":"Effect of Laurusnobilis extract and Atorvastatin on Liver and Kidney function of Hyperlipidemia Male Rats","authors":"Faraj Hato","doi":"10.37506/ijop.v10i1.3208","DOIUrl":"https://doi.org/10.37506/ijop.v10i1.3208","url":null,"abstract":"Introduction: Hyperlipidemia associated with increase of atherosclerosis and heart, blood vessels diseases. the present study was discuss of potentials effect of bay leave extract (BLE) and atorvastatin drug at diet with high fat, feeding rat types. Material and Methods: The Rats were randomly classificationfor 4 groups each group have 10 rats. control feed standard diet, group two rats feed HFD, group three rats feed HFD + ( BLE 250mg/kg ) and group four rats feed HFD + Atorvastatin 20 mg/kg in the experiment, the treatment done by gavage and treated with 4 weeks daily. Results and Conclusion : The results show increased significantly at the end body weights also the weight gain at group two by treated (HFD) , while hepatic levels was inhibited for the cholesterol, and also triglycerides, also the low-density lipoprotein cholesterol; While the hepatic levels and serum of high-density lipoprotein cholesterol may be increased when the animal treated 250 mg/kg BLE and 20mg/kg atorvastatin , also the result showed increased significantly in serum AST ,ALT, ALP, urea and creatinine in group of animals treated HFD , and caused decreased significantly in the value of above parameters when the animals treated 250 mg/kg BLE and 20mg/kg atorvastatin ,it reach the control. In conclusion, bay leave exerts and atorvastatin have amelioration effect against hyperlipidemia in HFD-fed rats.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69907061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of weight bearing exercises on Spastic Diplegic Children 负重运动对痉挛性双瘫儿童的影响

International journal of physiology Pub Date : 2022-01-01 DOI: 10.37506/ijop.v10i3.3294

引用次数: 0

Physiological and Motor Performance Characteristics in Rugby and Soccer Players: Data from a Developing Country 橄榄球和足球运动员的生理和运动表现特征:来自发展中国家的数据

International journal of physiology Pub Date : 2022-01-01 DOI: 10.37506/ijop.v10i4.3342

引用次数: 0

Comparative Study Of Physical Fitness Index And Predicted VO2max among Rural And Urban Female Students 城乡女大学生体质指数与预测VO2max的比较研究

International journal of physiology Pub Date : 2022-01-01 DOI: 10.37506/ijop.v10i2.3253

G.Suneethi

{"title":"Comparative Study Of Physical Fitness Index And Predicted VO2max among Rural And Urban Female Students","authors":"G.Suneethi","doi":"10.37506/ijop.v10i2.3253","DOIUrl":"https://doi.org/10.37506/ijop.v10i2.3253","url":null,"abstract":"Background: Physical fitness index (PFI) measures fitness for muscular work and ability to recover from work. It assess cardiopulmonary efficiency. Vo2 max refers to maximum amount of oxygen that an individual can utilize during intense exercise and is best indicator of cardiovascular fitness and aerobic endurance. PFI and Vo2 max are dependent on height, weight, BMI. Differences in anthropometry among urban and rural subjects due to different environmental, social, nutritional and life style habits can affect PFI and Vo2 max. Thus present study is intended to compare PFI and predicted Vo2 max among rural and urban female students . Materials and Methods: 50 participants of age group 18-20 years, 25 sedentary female subjects from each of rural and urban sectors of 1 st year MBBS were taken by random sampling. PFI was determined by modified Harvard step test and Vo2 max was determined by Indirect Queens college step test. Mean PFI was higher in rural group compared to urban group (p= 0.48). Mean Vo2 max was similar in both the groups (p=0.99). PFI was positively correlated with Vo2 max in both the groups (p<0.05). Conclusion: Rural female students do not have a statistically significant higher value of PFI and Vo2 max than urban female students.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69907694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Post – COVID 19 Sequelae: A Retrospective Study COVID - 19后后遗症评估:一项回顾性研究

International journal of physiology Pub Date : 2022-01-01 DOI: 10.37506/ijop.v10i2.3252

D. Celine, S.Suguna, M.Nishanth

{"title":"Assessment of Post – COVID 19 Sequelae: A Retrospective Study","authors":"D. Celine, S.Suguna, M.Nishanth","doi":"10.37506/ijop.v10i2.3252","DOIUrl":"https://doi.org/10.37506/ijop.v10i2.3252","url":null,"abstract":"Background: COVID–19 is an acute respiratory illness caused by SARS–CoV–2. COVID-19 created a major impact on physical, cognitive, mental health and social status in patients with SARS–CoV–2. Aim and Objective : To assess the post COVID sequelae in COVID19 recovered individuals. To assess the functional limitations using post COVID functional status scale after 4weeks of onset of illness. Materials and Methods : Subjects were selected from compiled list of Triage OP from Chengalpattu Medical College and Hospital. The semi structured questionnaire enclosed with Socio – demographic details, physical and socio – psychological domains based on COVID-19 Yorkshire Rehabilitation Screening tool (C19-YRS) were assessed and the impact of each domain was graded using a Likert scale. Post – COVID 19 functional status scale (PCFS) to assess functional limitations was also sent through Google form and the details were collected. Analysis: Collected data was analyzed using Microsoft Excel with descriptive statistics. Result: 1044 individuals participated in the study. On Assessment of post COVID sequelae fatigue was major symptom reported followed by cough and other neuropsychiatric symptoms. 53.4% of COVID recovered individuals had functional limitations and 2.4% of these individuals had severe functional limitations and they require assistance for daily living. Conclusion: Most COVID–19 recovered individuals had persistence of some clinical symptoms. From PCFS it was observed that 23% individuals had moderate to severe functional limitations, therefore early detection and rehabilitation measures are recommended.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69907687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetican Alysis of the Role of Connexin 37 Polymorphism in Spontaneous Abortion 连接蛋白37多态性在自然流产中的遗传分析

International journal of physiology Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3088

Nayela Sayeed, W. Nagadeepa, Vemulapalli Ravi Kumar

{"title":"Genetican Alysis of the Role of Connexin 37 Polymorphism in Spontaneous Abortion","authors":"Nayela Sayeed, W. Nagadeepa, Vemulapalli Ravi Kumar","doi":"10.37506/ijop.v9i4.3088","DOIUrl":"https://doi.org/10.37506/ijop.v9i4.3088","url":null,"abstract":"Introduction: Among unique cardiovascular risk factors in women are complications during pregnancy,including miscarriage. Important risk factor is also genetic background. One of powerful candidate genesfor cardiovascular disease of atherosclerotic origin (aCVD) is gene for connexin 37 (Cx37) with stronggene-environment interaction including smoking status, that is also strong risk factor for complications inpregnancy including spontaneous abortion (SA). Material and Methods: We analysed association betweenSA and Cx37 gene polymorphism (1019C>T; Pro319Ser) in 547 foetuses and its potential interaction withsmoking status of mothers. Using genetic analyses from women from general population as controls, ORsfor T allele, found in our previous studies to be protective against a CVD, were calculated. This study wasa secondary analysis of a randomized controlled trial. Results and Conclusion: T allele carriers (foetuses),had OR 0.91 (95 % CI 0.72-1.14) and no interaction with smoking was observed. In conclusion, no significantassociation between Cx37 polymorphism and SA was observed and no modifying effect of smoking statuson this association was detected.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46173148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study of Lipid Profile in Obese Hypertensive Subjects 肥胖高血压患者血脂水平的研究

International journal of physiology Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3086

Anant Kumar, R. Ranjan, Priyanka., V. Rani, R. Singh

{"title":"A Study of Lipid Profile in Obese Hypertensive Subjects","authors":"Anant Kumar, R. Ranjan, Priyanka., V. Rani, R. Singh","doi":"10.37506/ijop.v9i4.3086","DOIUrl":"https://doi.org/10.37506/ijop.v9i4.3086","url":null,"abstract":"Background: Obesity is a significant risk factor for metabolic syndrome in adults. Central fat distributiongreatly alters the lipid profile and induces atherogenic dyslipidemia even in normoglycaemic, nonhypertensivesubjects.Aim and Objectives: Hence, the aim of the present study to assess lipid profile changes in non-obesehypertensive subjects. Obesity, hypertension and dyslipidemia are the three highly significant risk factorfor the deranged lipid profile. Obesity can be defined as excess accumulation of body fat arising froma sustained or a periodic positive energy balance that when energy intake exceeds energy expenditure1.Indicators of overweight are useful in the diagnosis and management of obesity in both children and adults.Material & Methods: This study was conducted on newly diagnosed cases of essential hypertensionattending medical outdoor of M.G.M. Medical College, Kisangani. A complete clinical examinationincluding laboratory investigation was done to exclude any systemic or other diseases which are likely toaffect blood lipid levels directly or indirectly.Results- The association between dyslipidaemia, obesity and hypertension is well establishedand all havebeen found to be major risk factor for the development of CAD, a leading cause of visits to physician andcause of death .Conclusion: Our study was envisaged to know the effect of obesity on lipid profile profile only inhypertensive and not in general population, and the study found some definite but paradoxical effects.These are that in obesity on a background of hypertension, the total and LDL cholesterol as also the HDLcholesterol are decreased, but on use other hand, the value of VLDL cholesterol and triglycerides are grosslyand significantly increased. These finding have two major Clinical implications in that obese hypertensiveswill be more prone to metabolic syndrome and type 2 diabetes mellitus, and steps should be taken to preventthem accordingly and also apart from statins one should treat the obese hypertensives with fibrates, fatrestriction and physical exercise also.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43186925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study of Red Blood Cell Indices among Covid 19 Individuals in Tertiary Care Triage Centre 三级医疗分诊中心新冠肺炎患者红细胞指标的研究

International journal of physiology Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3085

A.Anitha, P.Sudhakar, S.Ramapriya

{"title":"A Study of Red Blood Cell Indices among Covid 19 Individuals in Tertiary Care Triage Centre","authors":"A.Anitha, P.Sudhakar, S.Ramapriya","doi":"10.37506/ijop.v9i4.3085","DOIUrl":"https://doi.org/10.37506/ijop.v9i4.3085","url":null,"abstract":"Background: SARS-CoV-2 infection is characterized by the development and progression of inflammatoryresponses. The exploration of prognostic predictors for patients with COVID-19 is vital for prompt clinicalintervention. Our study aims to explore the predictive value of hematological parameters in categorizationof patients with COVID-19.We aimed to investigate associations between hematological parameters anddisease severity in patients with SARS-CoV-2infection.The red blood cell distribution width (RDW),an indicator of anisocytosis has emerged as a potential tool for risk stratification of critically ill patients.Materials and Methods: Retrospective study after getting approval from Institutional ethics committeewas performed with data obtained from triage OPD in Chengalpattu Medical College & Hospital. Thedemographic, clinical, laboratory profile of COVID 19 positive patients who attended Triage OPD for aperiod of one month were collected. 3000 RT-PCR confirmed COVID positive patients of age group 20to 70 years of both genders were included in the study. COVID 19 positive paediatric cases, antenatal andpostnatal mothers, postoperative cases and sick cases admitted in COVID ICU were excluded from thestudy. Symptoms, associated co-morbidities and severity of COVID 19 were tabulated. Complete BloodCount measured by Automated Sysmex Analyser at the time of reporting to triage was noted. Red bloodcell indices were analysed using SPSS 21.0 version. Results: There was statistically significant increase inRDW and decrease in MCV among patients with co-morbidity and severe illness compared to those withmild disease. There is no statistically significant difference in Red blood cell indices between patients withand without symptoms and patients without co-morbidities. Conclusion: RDW was found to be a screeningtool to identify patients with severe COVID-19 and the results of this study suggest that RDW should be partof routine laboratory assessment and monitoring of COVID-19.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47200503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on Neutrophil Lymphocyte Ratio in Covid 19 Patients in Tertiary Care Centre 三级医疗中心新冠肺炎患者中性粒细胞比例的研究

International journal of physiology Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3087

Céline, T. Vijayalakshmi, G. Chandini

{"title":"A Study on Neutrophil Lymphocyte Ratio in Covid 19 Patients in Tertiary Care Centre","authors":"Céline, T. Vijayalakshmi, G. Chandini","doi":"10.37506/ijop.v9i4.3087","DOIUrl":"https://doi.org/10.37506/ijop.v9i4.3087","url":null,"abstract":"Introduction: COVID-19 pandemic is spread by droplet infectionwith symptoms of fever, cough,diarrhea,dyspnea, fatigue, myalgia, headache, anosmia and ageusia. Morbidity and mortality is higher amongelderly and in patients with comorbidities especially Diabetes Mellitus(DM). Biomarkers of inflammationare potential predictors for prognosis in covid patients.Aim: To analyze the association of NLR in covid 19 patients with symptoms and diabetic status Objective:1. To studyNLR in covid 19 patients with and without symptoms2. To study the association of NLR between diabetic and non-diabetic covid 19 patients.3. To study the association between symptomatology and NLR in diabeticcovid 19 patients.Methodology: 3000 RT-PCR confirmed Covid 19 patients who attended triage op were included afterEthicscommittee approval.Patients were grouped as patients with and without symptoms and patients with andwithout DM.The diabetic Covid patients were also analyzed based on the symptoms. Blood samplesonreporting were used for analysis of NLR andparameters analyzed using SPSS23.0 version.Result: There is no statistically significant difference in NLR among Covid symptomatic and asymptomaticpatients. But NLR is markedly raised in covid symptomatic patients with diabetes mellitus.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48253627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Descriptive Study to Assess the Perceptions of Undergraduate Medical Students Towards Acceptance of E-Learning Vs Conventional Methods in An Integrated Curriculum in Physiology 一项描述性研究评估本科医学生在生理学综合课程中对接受电子学习与传统方法的看法

International journal of physiology Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3090

S. Ali, Hifzur Rehman, P. Ba

{"title":"A Descriptive Study to Assess the Perceptions of Undergraduate Medical Students Towards Acceptance of E-Learning Vs Conventional Methods in An Integrated Curriculum in Physiology","authors":"S. Ali, Hifzur Rehman, P. Ba","doi":"10.37506/ijop.v9i4.3090","DOIUrl":"https://doi.org/10.37506/ijop.v9i4.3090","url":null,"abstract":"Background: Institutions across the world have shifted to virtual education to keep the academic activitiesgoing due to the COVID-19 pandemic jeopardizing the academiccalendars. E-learning was being used asa part of distance learning courses but the preparedness, designing and effectiveness in using it towardsconducting regular courses have been the main concern in countries where students are not used to virtualclasses due to technical constraints like faculty training, suitability of devices and bandwidth availabilityposing a serious challenge. Methods: A cross-sectional, web-based study was done among 50 second yearmedical undergraduate students in 2020. A standardized, electronic, self-administered, Google Form datacollection sheet was distributed. It included the seven components to evaluate; Course Schedule, objectives,time management, teaching methods, assessment methods, academic achievement and student concerns.Descriptive, inferential statistics were applied. Results: e-learning has been accepted very well by thestudents (48%) and they found it to add as a better learning resource (44%). About 25% of students find bothe-leaning and conventional methods as convenient in learning.The major advantage in conventional methodswere due to peer interaction, student-faculty interaction and active participation of faculty with feedback.Conclusion: Most of the students appraised that e-learning can be used as complementary to conventionalmethods. The conventional methods had an upper hand in long term; teaching concepts, peer interaction andfaculty feedback with better planning and implementation of curricular activities holding the key for successin fulfilling the expected outcomes by either of the methods.","PeriodicalId":92916,"journal":{"name":"International journal of physiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44710109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0