Brain Circulation最新文献_第9页

Inverted gull-wing hinge decompressive craniotomy for infantile acute subdural hematoma: A case report. 倒置鸥翼铰链减压开颅术治疗小儿急性硬膜下血肿1例。

IF 1.9 4区医学

Brain Circulation Pub Date : 2023-01-01 DOI: 10.4103/bc.bc_69_22

Yu Okuma, Takao Yasuhara, Ittetsu Kin, Shigeru Daido, Isao Date

引用次数: 0

Lecanemab: A hope in the management of Alzheimer's disease Lecanemab:阿尔茨海默病治疗的希望

4区医学

Brain Circulation Pub Date : 2023-01-01 DOI: 10.4103/bc.bc_10_23

LV Simhachalam Kutikuppala, Nandita Thakkar, PreethamBasil Martis, SaiKiran Kuchana, RanjanK Mohapatra

引用次数: 0

A double-hit: End-stage renal disease patients suffer worse outcomes in intracerebral hemorrhage 双重打击:终末期肾病患者脑出血的预后更差

4区医学

Brain Circulation Pub Date : 2023-01-01 DOI: 10.4103/bc.bc_24_23

Fawaz Al-Mufti, AidenK Lui, Fangyi Lin, Anaz Uddin, Bridget Nolan, Kevin Clare, Terry Nguyen, Eris Spirollari, Eric Feldstein, Yarden Bornovski, Jose Dominguez, George Coritsidis, ChiragD Gandhi

{"title":"A double-hit: End-stage renal disease patients suffer worse outcomes in intracerebral hemorrhage","authors":"Fawaz Al-Mufti, AidenK Lui, Fangyi Lin, Anaz Uddin, Bridget Nolan, Kevin Clare, Terry Nguyen, Eris Spirollari, Eric Feldstein, Yarden Bornovski, Jose Dominguez, George Coritsidis, ChiragD Gandhi","doi":"10.4103/bc.bc_24_23","DOIUrl":"https://doi.org/10.4103/bc.bc_24_23","url":null,"abstract":"BACKGROUND: Intracerebral hemorrhage (ICH) carries significant morbidity and mortality. Previous single-center retrospective analysis suggests that end-stage renal disease (ESRD) is a risk factor for severe ICH and worse outcomes. This investigation aims to examine the impact of ESRD on ICH severity, complications, and outcomes using a multicenter national database. METHODS: The International Classification of Disease, Ninth and Tenth Revision Clinical Modification codes were used to query the National Inpatient Sample for patients with ICH and ESRD between 2010 and 2019. Primary endpoints were the functional outcome, length of stay (LOS), and in-hospital mortality. Multivariate variable regression models and a propensity-score matched analysis were established to analyze patient outcomes associated with baseline patient characteristics. RESULTS: We identified 211,266 patients with ICH, and among them, 7,864 (3.77%) patients had a concurrent diagnosis of ESRD. Patients with ESRD were younger (60.85 vs. 67.64, P < 0.01) and demonstrated increased ICH severity (0.78 vs. 0.77, P < 0.01). ESRD patients experienced higher rates of sepsis (15.9% vs. 6.15%, P < 0.01), acute myocardial infarction (8.05% vs. 3.65%, P < 0.01), and cardiac arrest (5.94% vs. 2.4%, P < 0.01). In addition, ESRD predicted poor discharge disposition (odds ratio [OR]: 2.385, 95% confidence interval [CI]: 2.227–2.555, P < 0.01), longer hospital LOS (OR: 1.629, 95% CI: 1.553–1.709, P < 0.01), and in-hospital mortality (OR: 2.786, 95% CI: 2.647–2.932, P < 0.01). CONCLUSIONS: This study utilizes a multicenter database to analyze the effect of ESRD on ICH outcomes. ESRD is a significant predictor of poor functional outcomes, in-hospital mortality, and prolonged stay in the ICH population.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135749652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for multiple recurrent ischemic strokes. 多次复发性缺血性中风的危险因素。

IF 1.9 4区医学

Brain Circulation Pub Date : 2023-01-01 DOI: 10.4103/bc.bc_73_22

Nevzat Uzuner, Gulnur Tekgol Uzuner

{"title":"Risk factors for multiple recurrent ischemic strokes.","authors":"Nevzat Uzuner, Gulnur Tekgol Uzuner","doi":"10.4103/bc.bc_73_22","DOIUrl":"https://doi.org/10.4103/bc.bc_73_22","url":null,"abstract":"Background: Cardiovascular diseases, hypertension, diabetes mellitus, dyslipidemia, and atrial fibrillation are the most common modifiable risk factors for recurrent ischemic stroke. In this study, we aimed to find the risk factors associated with more than two recurrent ischemic strokes after the first-ever stroke.Methods: We collected the ischemic stroke patients in our stroke registry data bank, and the eligible patients were followed for recurrent ischemic stroke after 2008. Our study consisted of 927 patients who were followed up for 9 years after the first-ever stroke.Results: We found that 185 (20%) patients had a recurrent ischemic stroke, and another 32 (3.5%) patients had more than one recurrence after the first-ever ischemic stroke. The mean time for the first stroke recurrence was 1 year, and the mean time for the multiple stroke recurrences was 3 years. Significant risk factors for multiple recurrences were congestive heart disease (P < 0.015) and diabetes mellitus (P < 0.006).Conclusions: We concluded that even with the appropriate treatments, patients with congestive heart disease and diabetes mellitus have a higher rate of multiple recurrences for ischemic stroke after the first-ever ischemic stroke, indicating that more attention should be paid to this issue.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"9 1","pages":"21-24"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/31/BC-9-21.PMC10158663.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9782984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Research progress of selective brain cooling methods in the prehospital care for stroke patients: A narrative review. 选择性脑冷却方法在脑卒中患者院前护理中的研究进展

IF 1.9 4区医学

Brain Circulation Pub Date : 2023-01-01 DOI: 10.4103/bc.bc_88_22

Xi Chen, Hong An, Di Wu, Xunming Ji

引用次数: 1

Effectiveness of pharmacologic interventions for prevention of cerebral hyperperfusion syndrome following bypass surgery. 药物干预预防搭桥术后脑过度灌注综合征的有效性。

IF 1.9 4区医学

Brain Circulation Pub Date : 2022-12-06 eCollection Date: 2022-10-01 DOI: 10.4103/bc.bc_43_22

Georgios P Skandalakis, Aristotelis Kalyvas, Evgenia Lani, Spyridon Komaitis, Danai Manolakou, Despoina Chatzopoulou, Nikos Pantazis, Georgios A Zenonos, Constantinos G Hadjipanayis, George Stranjalis, Christos Koutsarnakis

{"title":"Effectiveness of pharmacologic interventions for prevention of cerebral hyperperfusion syndrome following bypass surgery.","authors":"Georgios P Skandalakis, Aristotelis Kalyvas, Evgenia Lani, Spyridon Komaitis, Danai Manolakou, Despoina Chatzopoulou, Nikos Pantazis, Georgios A Zenonos, Constantinos G Hadjipanayis, George Stranjalis, Christos Koutsarnakis","doi":"10.4103/bc.bc_43_22","DOIUrl":"10.4103/bc.bc_43_22","url":null,"abstract":"Background: Cerebral hyperperfusion syndrome (CHS) following bypass surgery is a major cause of neurological morbidity and mortality. However, data regarding its prevention have not been assorted until date.Objective: The objective of this study was to review the literature and evaluate whether any conclusion can be drawn regarding the effectiveness of any measure on preventing bypass-related CHS.Methods: We systematically reviewed PubMed and Cochrane Library from September 2008 to September 2018 to collect data regarding the effectiveness of pharmacologic interventions on the refers to pretreatment (PRE) of bypass-related CHS. We categorized interventions regarding their class of drugs and their combinations and calculated overall pooled estimates of proportions of CHS development through random-effects meta-analysis of proportions.Results: Our search yielded 649 studies, of which 23 fulfilled inclusion criteria. Meta-analysis included 23 studies/2,041 cases. In Group A (blood pressure [BP] control), 202 out of 1,174 pretreated cases developed CHS (23.3% pooled estimate; 95% confidence interval [CI]: 9.9-39.4), Group B (BP control + free radical scavenger [FRS]) 10/263 (0.3%; 95% CI: 0.0-14.1), Group C (BP control + antiplatelet) 22/204 (10.3%; 95% CI: 5.1-16.7), and Group D (BP control + postoperative sedation) 29/400 (6.8%; 95% CI: 4.4-9.6)].Conclusions: BP control alone has not been proven effective in preventing CHS. However, BP control along with either a FRS or an antiplatelet agent or postoperative sedation seems to reduce the incidence of CHS.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"8 4","pages":"207-214"},"PeriodicalIF":1.9,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/e8/BC-8-207.PMC10167845.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9470890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroprotective approach in acute ischemic stroke: A systematic review of clinical and experimental studies. 急性缺血性脑卒中的神经保护方法：临床和实验研究的系统综述。

IF 1.9 4区医学

Brain Circulation Pub Date : 2022-12-06 eCollection Date: 2022-10-01 DOI: 10.4103/bc.bc_52_22

Fettah Eren, Sueda Ecem Yilmaz

{"title":"Neuroprotective approach in acute ischemic stroke: A systematic review of clinical and experimental studies.","authors":"Fettah Eren, Sueda Ecem Yilmaz","doi":"10.4103/bc.bc_52_22","DOIUrl":"10.4103/bc.bc_52_22","url":null,"abstract":"Ischemic stroke is a disease with worldwide economic and social negative effects. It is a serious disease with high disability and mortality. Ionic imbalance, excitotoxicity, oxidative stress, and inflammation are induced during and after ischemic stroke. Cellular dysfunction, apoptosis, and necrosis are activated directly or indirectly mechanisms. The studies about neuroprotection in neurodegenerative diseases have increased in recent years. Data about the mechanisms of progressive molecular improvement in the brain tissue are increasing in acute ischemic stroke. Based on these data, preclinical and clinical studies on new neuroprotective treatments are being designed. An effective neuroprotective strategy can prolong the indication period of recanalization treatments in the acute stage of ischemic stroke. In addition, it can reduce neuronal necrosis and protect the brain against ischemia-related reperfusion injury. The current review has evaluated the recent clinical and experimental studies. The molecular mechanism of each of the neuroprotective strategies is also summarized. This review may help develop future strategies for combination treatment to protect the cerebral tissue from ischemia-reperfusion injury.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"8 4","pages":"172-179"},"PeriodicalIF":1.9,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/fc/BC-8-172.PMC10167855.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9468683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Diffuse large B-cell lymphoma: An uncommon diagnosis at the cerebellopontine angle - A case report. 弥漫性大B细胞淋巴瘤：桥小脑角的一种罕见诊断——一例报告。

IF 1.9 4区医学

Brain Circulation Pub Date : 2022-12-06 eCollection Date: 2022-10-01 DOI: 10.4103/bc.bc_46_22

Punit Kumar, Amit Kumar Ghosh, Soutrik Das

引用次数: 0

Isolated cerebellar infarction in a case of JAK 2 mutation-negative polycythemia vera: A case report. JAK2突变阴性真性红细胞增多症患者的孤立性小脑梗死：一例报告。

IF 1.9 4区医学

Brain Circulation Pub Date : 2022-12-06 eCollection Date: 2022-10-01 DOI: 10.4103/bc.bc_37_22

Prasad Krishnan

引用次数: 0

Cerebral venous sinus thrombosis in pregnancy and puerperium: A comprehensive review. 妊娠期和产褥期脑静脉窦血栓形成：一项综合综述。

IF 1.9 4区医学

Brain Circulation Pub Date : 2022-12-06 eCollection Date: 2022-10-01 DOI: 10.4103/bc.bc_50_22

Hussein Algahtani, Abdulrahman Bazaid, Bader Shirah, Raghad N Bouges

{"title":"Cerebral venous sinus thrombosis in pregnancy and puerperium: A comprehensive review.","authors":"Hussein Algahtani, Abdulrahman Bazaid, Bader Shirah, Raghad N Bouges","doi":"10.4103/bc.bc_50_22","DOIUrl":"10.4103/bc.bc_50_22","url":null,"abstract":"Cerebral venous sinus thrombosis (CVST) is a distinct neurological emergency caused by occlusion, either partial or complete, of the dural venous sinus and/or the cerebral veins. It occurs more frequently in women during pregnancy and puerperium as compared to the general population. The clinical diagnosis is difficult in some cases due to its variable clinical presentation with numerous causes and risk factors. The diagnosis can be made at an early stage if clinical suspicion is high with the help of advanced neuroimaging techniques that were developed recently. Early therapeutic intervention using anticoagulants allows for preventing complications and improving outcomes. In this article, we review the topic of CVST in pregnancy and the postpartum period with an emphasis on its epidemiology, pathophysiology, clinical presentation, and treatment. We also elaborate on several practical points that are important to the treating team. This review will help obstetricians, neurologists, and emergency physicians diagnose affected pregnant women as early as possible to provide prompt treatment and avoid adverse outcomes.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"8 4","pages":"180-187"},"PeriodicalIF":1.9,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/55/BC-8-180.PMC10167849.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9473967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1