International journal of diabetes and clinical research最新文献

{"title":"The Level of Satisfaction of Diabetic Patients with Healthcare Personnel Attending Outpatient Health Clinics in Jamaica","authors":"B. Paula, M. Donovan, Ragoobirsingh Dalip","doi":"10.23937/2377-3634/1410101","DOIUrl":"https://doi.org/10.23937/2377-3634/1410101","url":null,"abstract":"Introduction: The burden of diabetes mellitus is increasing in low-income and middle-income countries, and it is a major contributor to premature mortality. The care of patients with diabetes mellitus is multidisciplinary and involves a number of healthcare personnel. Effective communication between diabetic patients and healthcare personnel influence selfmanagement and health outcomes. Aim: The study evaluated the diabetic patient’s assessment of the communication skills of the healthcare providers, as well as an assessment of the patients’ understanding of the health information. Method: The study is a cross-sectional design using primarily a quantitative methodology. The study population consisted of 101 diabetic patients. A 14-point interviewer administered questionnaire was used to solicit information on socio-demographics, medical history, rating of provider communication, and the evaluation of specific health care workers and information sharing. The data was analysed using SPSS version 17.0 and Microsoft Excel 2007. Descriptive statistical analysis was applied with a 95% confidence level and a precision ± 5%. Results: The findings revealed that 45.5% of diabetic patients rate the level of communication with regards to health worker sharing information about diabetes mellitus and its management as ‘very good’ (45.5%) with a the mean score was 2.79 ± 0.86. Descriptive analysis revealed that 52.5% of respondents were generally satisfied with the providers’ communication, while 47.5% was not (mean score obtained 9.6 ± 2.77). There was no association between total satisfaction and gender (p = 0.065), neither with age (p = 0.813), education level (p = 0.153) or employment status (p = 0.701). Conclusion: The findings from this study revealed that the level of communication of information by the healthcare personnel about diabetes mellitus and its management was very good. Just about one-half of the respondents were generally satisfied with the provider’s communication. The multidisciplinary approach to care of diabetic patients by healthcare professionals should be structured to promote better communication by maximizing the presentation and exchange of information, and better understanding of diabetes care. ReseaRch aRticle","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44896115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Thyroid Stimulating Hormone and Free Thyroxine with Urinary Albumin Excretion in Euthyroid Subjects with Type 2 Diabetes Mellitus","authors":"K. Aljabri, Ibrahim M Alnasser, Facharatz Facharatz, S. Bokhari, Muneera Alshareef, Patan Murthuza Khan, Abdulla M Mallosho, H. M. Abuelsaoud, Mohammad M Jalal, Rania F Safwat, Rehab El Boraie, Nawaf K Aljabri, Bandari K Aljabri, Arwa Y Alsuraihi, Amjad I Hawsawi","doi":"10.23937/2377-3634/1410102","DOIUrl":"https://doi.org/10.23937/2377-3634/1410102","url":null,"abstract":"","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48135783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Type 2 Diabetes Prevalence, Distribution and Risk Factors in St. Kitts and Nevis, West Indies.","authors":"Jeanita W Richardson, Kelsie D Kelly, Trina K Kumodzi, Nicole Slack Liburd, Hazel Laws","doi":"10.23937/2377-3634/1410114","DOIUrl":"10.23937/2377-3634/1410114","url":null,"abstract":"<p><strong>Objectives: </strong>This study in collaboration with the St. Kitts & Nevis Ministry of Health (MOH) investigated the prevalence of type 2 diabetes and its risk factors, the second leading cause of death in the country.</p><p><strong>Methods: </strong>Medical records of patients between the ages of 18 and 75 as of January 1, 2010 treated between January 1, 2010 and December 31, 2015 in the government-funded health centers (HCs) were eligible for inclusion (N = 2737). All HC visits (n = 4169) generated by a representative sample of patients (n = 761) were evaluated using Caribbean Public Health Association Public Health Association (CARPHA) guidelines for risk ranges.</p><p><strong>Results: </strong>The prevalence of type 2 diabetes is 23% and is concentrated in the 45-64 year-old cohort. Though women outnumber men 3:1 in the sample, gender-prevalence rates are similar (23% and 22% respectively). There is also evidence that comorbidities are prevalent among diabetics (76%) and many nondiabetics are at risk of diabetes (20%).</p><p><strong>Conclusion: </strong>This study confirmed the MOH's concerns that type 2 diabetes presents local risk and brings into question historic assumptions that women are at greater risk of diabetes than men.</p>","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37540819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Complications and Composition of the Intestinal Microbiome in Patients with Type 2 Diabetes","authors":"Siegel Eg, B. J. Lorenzo, I. Flade, C. Hasslacher","doi":"10.23937/2377-3634/1410086","DOIUrl":"https://doi.org/10.23937/2377-3634/1410086","url":null,"abstract":"Background: The composition of the gut microbiome appears to exert an influence on the development of cardiovascu lar complications (CVCs). We investigate here the relation ship between the composition of the gut microbiome and the prevalence of CVCs in patients with type 2 diabetes. Methods: Demographic characteristics, routine laboratory results, data on the prevalence of CVCs and the compo sition of the gut microbiome assessed by 16S rRNA se quencing logistic butyrate-producing bacteria. These findings may reflect an impaired intestinal barrier and should be investigated in future prospective studies. Glo merular Filtration Percutaneous Transluminal Angioplasty; Ischemic TMA: Trimethylamine","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45745070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin Acts as Stimulatory Agent in Diabetes-Related Escherichia Coli Pathogenesis","authors":"Madacki-Todorović Kamelija, Eminović Izet, Mehmedinović Nadira Ibrišimović, I. Mirza","doi":"10.23937/2377-3634/1410098","DOIUrl":"https://doi.org/10.23937/2377-3634/1410098","url":null,"abstract":"Background: In general, diabetic patients are more prone to microbial infections, which is believed to be caused due to high glucose levels in blood which compromise components of the immune system. However, it is little known about role of therapeutic insulin administration on dissemination of infectious diseases in people with diabetes mellitus. Methods: The study included the clinically isolated strains of Escherichia coli (E. coli) with biofilm forming capacity as well as referent non-biofilm former E. coli strain as control. Metabolic activity, level of virulence and biofilm forming capacity of tested E. coli strains were investigated in vitro conditions under presence of human hormone insulin at different incubation time points. Results: Administration of hormone insulin in concentration of 2.5 U/ml resulted in significant increase in proliferation of all tested E. coli strains under in vitro conditions at 37 °C. Presence of insulin also stimulated expression of E. coli virulent factor enzyme aspartyl proteinase, which in synergism with human insulin served as signal molecules for bacterial quorum sensing and biofilm formation. Conclusion: Results of this study present first report about direct effect of hormone insulin on elevated metabolic activity of E. coli in a linkage with its biofilm forming capability. This opens a new look at understanding the cause of various bacterial infections in diabetic patients, as well as their multi-resistance to antibiotics that occurs due to changed bacterial metabolism and their newly acquired colonization abilities.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44852072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Pharmacist Role in Diabetes Education in Sri Lanka: A Cross-Sectional Descriptive Randomized Step-Up Study","authors":"Cooray Bulathsinghalage Poornima Reshamie, Morrissey Hana, Waidyarathne Eisha Indumani, Ball Patrick Anthony, Sumanathilake Manilka","doi":"10.23937/2377-3634/1410085","DOIUrl":"https://doi.org/10.23937/2377-3634/1410085","url":null,"abstract":"Introduction: The prevalence of Type 2 diabetes is globally on the rise, in both developed and developing countries. Type 2 diabetes is a major public health issue in Sri Lanka. This study aims to investigate the effect of structured self-management health education intervention based on ‘PITS model’ (Pathophysiology, Indications, Treatment and Specifics) would result in a clinically significant improvement in glycaemic control of type 2 Diabetes Mellitus (T2DM) patients. Methods: Patients who were diagnosed with T2DM at two tertiary care hospitals in Sri Lanka, comply with the selection criteria were enrolled to the study. The intervention consisted with two repeated one to one education sessions followed up in six and twelve months. HbA1c, lipid profiles, waist circumference, BMI and other biomedical measurements were done in both groups. Analysis of covariance between groups were conducted to determine the effectiveness of the intervention. Results: Mean HbA1c level in both intervention and usual care group was 8.6% with deviation from their target glycaemic level (6.5%,48 mmol/mol) at baseline. At six months, there was a significant reduction (P<0.001; size of effect = 0.69) in HbA1c between the intervention and the usual care group controlling the baseline values. Conclusion: The results demonstrate the effectiveness of one to one diabetes self-management intervention among the adults with T2DM.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41795510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Urinary Tract Infections and Allergic Conditions among Type 2 Diabetes Mellitus Patients in Rural Hospital Clinics in Sri Lanka","authors":"Sachinthana Jga, Kariyawasam Gm, Edirisinghe Emdt, Peiris Hsn, Dayara-thna Dark, Mowlana Fm, Jayasekara Jmkb","doi":"10.23937/2377-3634/1410097","DOIUrl":"https://doi.org/10.23937/2377-3634/1410097","url":null,"abstract":"Background: Urinary tract infections (UTI) and allergic conditions in individuals with diabetes mellitus (DM) may evolve to serious complications unless managed properly. Early diagnosis and evaluation of these conditions of DM patients are important to maintain the quality of life of the patients. The objective of the current study was to identify the incidence of UTIs among type 2 DM patients. Method: A retrospective cross-sectional study was conducted on 260 type 2 DM patients, who participated in a diabetic clinic conducted in the District General Hospital, Ampara. The study was conducted for a period of one month. Information like demography, history of UTI reported in the last 12 months, glycemic control of patients and other relevant details were collected via a questionnaire. In addition, Urine Full Report (UFR) of spot urine sample and Full Blood Count (FBC) investigations were performed in the hospital laboratory and analyzed. Results: The incidence of UTI in the study population was 27.2% (n = 72). UFR showed 25% of the study population had evidence of UTI (presence of 10 or more puss cells/ high power field of the microscope). A significant association was noticed between the incidence of UTI and the gender (p < 0.01). High incidence of UTI was observed in females (81.9%) with a relative risk of 2.0 (95% CI 0.208, 0.701). Moreover, the study showed a statistically significant association between the incidence of UTI (p < 0.05, relative risk, 2.5 (95% CI = 1.053, 5.936)) and female patients having poor glycemic control. A statistically significant association was also shown between the incidence of UTI and the duration of DM (p < 0.05) which was seen to be greater than 6.5 years. The incidence of allergic conditions in the study population was 25.8% (n = 67). RESEARcH ARTiclE","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49438521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinc Supplementation Attenuated Calcium-High Diet Effect on Zinc Status and Carbohydrate Metabolism of Non-Diabetic and Diabetic Rats","authors":"Derouiche Samir, Kechrid Zine","doi":"10.23937/2377-3634/1410095","DOIUrl":"https://doi.org/10.23937/2377-3634/1410095","url":null,"abstract":"Background: The bioavailability of zinc can be influenced by several dietary factors, among them calcium level, which leads to zinc metabolism disturbance. Thus, the present study was under taken to evaluate the effect of zinc supplementation on zinc status and carbohydrate metabolism in non-diabetic and diabetic rats fed high-calcium diet. Methods: Sixty male Wistar rats were randomly divided into six equal groups. The first and fourth groups were non-diabetic and diabetic controls respectively. The second, third, fifth and sixth groups were calcium, calcium + zinc, diabetes + calcium and diabetes + calcium + zinc groups, respectively. Diabetes in fourth, fifth and sixth groups were induced by alloxan. Calcium (35 mg/kg feed) as CaCO3 and zinc (231 mg/kg feed) as ZnSO4.7H2O in feed were supplemented to the animals in groups for 21 days. Results: High dietary calcium significantly decreased body weight gain, serum zinc, tissue zinc levels, alkaline phosphatase, lactic dehydrogenases and aldolase activities and led to an increase of cholesterol, transaminases and uric acid concentrations in both diabetic and non-diabetic rats. However, zinc supplementation in animals fed calcium assured a partial correction of the previous parameters. Conclusion: The investigation revealed that zinc supplementation has a positive role against the negative effect of calcium, which provoked metabolic disturbance in diabetic and non-diabetic rats.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48137329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Individual Health Education on Health Literacy: Evaluation of the Translated Version (Sinhala) of Health Education Impact Questionnaire in Type 2 Diabetes","authors":"Cooray Bulathsinghalage Poornima Reshamie, Morrissey Hana, Waidyarathne Eisha Indumani, Ball Patrick Anthony, Sumanathilake Manilka","doi":"10.17554/J.ISSN.2414-2409.2018.01.5","DOIUrl":"https://doi.org/10.17554/J.ISSN.2414-2409.2018.01.5","url":null,"abstract":"Introduction: Type 2 diabetes mellitus and its complications is increasingly prevalent in Sri Lanka. Patients with low health literacy worsen the glycaemic control and diabetes complications. However, lack of studies on the effect of health literacy that affects clinical health outcomes and the effect of health education on it. Aim: This study aimed to evaluate the effect of health education impact questionnaire, translated into Sinhala is an appropriate tool to evaluate the impact of health education program for type 2 diabetes patients based on literacy improvement. Methods: This project was designed as a preliminary case-control study, with health education as the main intervention. Repeated health-education interventions were compared to the control group at baseline, followed up at six and 12 months. The improvements in knowledge assessed through health education impact questionnaire that was translated and culturally adapted to Sinhala language. Results: The study outcomes from 150 patients reveal that all heiQTM domains showed at least low to moderate correlations with the follow ups in intervention while, small effect had been shown in health service navigation in control group. Conclusion: This study reveals that the translated version of health education questionnaire well adapted in assessing knowledge improvement among Sri Lankan participants with type 2 diabetes.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41456146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin Resistance Modification is a Game Changer for Type 2 Diabetes Treatment Strategy","authors":"Gmitrov Juraj","doi":"10.23937/2377-3634/1410096","DOIUrl":"https://doi.org/10.23937/2377-3634/1410096","url":null,"abstract":"Insulin resistance, appearing years before diabetes main diagnostic sign, hyperglycemia, stands in the origin of type 2 diabetes (T2DM), generated by complex impairment of a spectrum biochemical processes the most important of which is the failure of phosphatidylinositol 3-kinase enzymatic chain responsible for glucose uptake and endothelial nitric oxide (NO) synthase activation. Therefore in conditions with insulin resistance the impairment of glucose uptake is strongly coupled with NO deficit and severe vasodilatory dysfunction. However T2DM conventional treatment even worsens diabetes fundamental pathophysiological mechanisms reflected by aggravated obesity and insulin resistance. These may generate vasodilatory dysfunction, arterial hypertension and dyslipidemia, diminishing intensive glycemic control mainly microvascular benefit. Glucocentric model of T2DM management should be replaced by approach focused primarily to impede insulin resistance rather then manage its cardiometabolic consequences. Antidiabetics should be selected to achieve hypoglycemic goals without increase of body weight and with ability to decrease insulin resistance, the key triggering factor of global vascular impairment and T2DM cardiovascular mortality.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45539911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}