International journal of diabetes and clinical research最新文献

{"title":"Insulin Injection Abscesses caused by Bacteria of the Burkholderia cepacia Complex","authors":"Alam Md Ejaz, Bhat Mohammad Hayat Ahmad, Patto Shoiab M, Bhat Mohammad Afaan","doi":"10.23937/2377-3634/1410174","DOIUrl":"https://doi.org/10.23937/2377-3634/1410174","url":null,"abstract":"","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":"73 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycaemic Control and Weight Reduction in Type 2 Diabetes Mellitus Patient Using a Wholly Nigerian Diet - A Hospital Based Study","authors":"Akoko Sokiprim, Siminialayi Iyeopu M, Chinenye Sunday","doi":"10.23937/2377-3634/1410172","DOIUrl":"https://doi.org/10.23937/2377-3634/1410172","url":null,"abstract":"","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":"101 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139133789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remission of Type 2 Diabetes with High-Fiber, Low-Fat, and Calorie Restricted Plant-Based Diet Study","authors":"Panigrahi Gunadhar","doi":"10.23937/2377-3634/1410167","DOIUrl":"https://doi.org/10.23937/2377-3634/1410167","url":null,"abstract":"Background: Type 2 Diabetes (T2D) is a chronic progressive disease, and its prevalence is on the rise around the world. Despite advances in pharmacotherapy, mitigating the burden of the disease on individuals, societies and the healthcare system remains a challenge. Remission has emerged as a therapeutic target in T2D with wide range of interventions. A plant-based diet seems to be promising to achieve","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48763430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back to the Beginning: Diagnosis Experiences of Persons with Type Two Diabetes","authors":"Haase Christie","doi":"10.23937/2377-3634/1410170","DOIUrl":"https://doi.org/10.23937/2377-3634/1410170","url":null,"abstract":"Background: One in ten adults in the United States has diabetes; the vast majority are diagnosed with type two diabetes mellitus (T2DM). Even though diabetes care has significantly evolved, and a wide variety of pharmacological treatments are available, approximately one-half of people with type two diabetes do not achieve a hemoglobin A1C of less than seven percent. In addition, self-management is a consequential contributor to glycemic control. In light of the mortality, morbidity, decreased quality of life, and financial burden caused by T2DM, the author wanted to explore the diagnosis experiences of type two diabetics. Could their experiences be a contributing factor to less-than-optimal treatment outcomes? Methods: The author interviewed nine consenting adults with T2DM in person, over the telephone, and via videoconference over four weeks in March and April 2023. The data from each transcript was analyzed independently and then compared, identifying meanings and clustering themes found throughout utilizing descriptive phenomenology as the underpinning for this study.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49118754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Predictors of Diabetic Retinopathy among Newly Diagnosed Type 2 Diabetic Patients at Chronic Follow-Up Clinic of University of Gondar Specialized Hospital: A Retrospective Follow-Up Study","authors":"Tassew Worku Chekol, Birhan Nigussie, Zewdu Yemataw","doi":"10.23937/2377-3634/1410169","DOIUrl":"https://doi.org/10.23937/2377-3634/1410169","url":null,"abstract":"Background: Diabetic retinopathy is a complication of type 2 diabetes resulting from long-term accumulated damage to retinal blood vessels and one of the life-threatening complications and is the most common cause of acquired blindness in adults and it affects 93 million people worldwide. DR is the principal cause of blindness in adults of working age and responsible for a worsening in quality of life despite preventable and treatable causes. To date, most of the epidemiological research on DR in Ethiopia has been limited to prevalence estimates from cross-sectional studies. This study determined the incidence of retinopathy and its predictors among type 2 diabetic patients Methods: Hospital-based retrospective follow-up study was conducted among 420 adults with newly diagnosed type 2 diabetic patients from January 1, 2014, to December 31, 2019. Data were extracted from medical records and entered into Epi info version7.2.2.6and exported to Stata 14 for analysis. Bivariable and multivariable Cox proportional hazard model were used to identify predictors of diabetic retinopathy. In a multivariable analysis variable having a p-value < 0.05 in the Cox; PH model was considered as predictors of diabetic retinopathy. Results: Overall, 19.5% (95% CI; 16.2-23.8) of the study population developed diabetic retinopathy, with a median survival time of 30.4 months. Congestive heart failure [AHR: 2.53 (95% CI; 1.49, 4.29)], chronic kidney disease [AHR: 5.02(95% CI; 2.73, 9.26)], hypertension [AHR: 2.07(95% CI; 1.17, 2.89)], and HBA1c [AHR: 10.5 (95% CI; 5.6, 19.6)] were found to be predictors of diabetic retinopathy.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41317562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Hyperglycemia on Outcome in COVID-19 Patients with Known Diabetes: A Retrospective Observational Study","authors":"Singh Yudhyavir, S. Abhishek, Surbhi Surbhi, Soni Kapil Dev, Aggarwal Richa, Trikha Anjan","doi":"10.23937/2377-3634/1410168","DOIUrl":"https://doi.org/10.23937/2377-3634/1410168","url":null,"abstract":"Background: The blood glucose level in a patient with diabetes is an important prognostic factor for any form of severe illness requiring intensive care hospitalization. We conducted this retrospective study to examine the effect of hyperglycemia on outcomes in patients with diabetes with coronavirus diseases (COVID-19) admitted to the intensive care unit (ICU). Method: A retrospective analysis of 25 adult patients with diabetes with COVID-19 admitted to the ICU between 1st January to 15 th February 2021 was done. Demographics details, past medical history, random blood sugar, medical management, ventilatory requirements, and survival data were obtained from medical record files and computerized patient recording systems. Outcomes such as mortality, need for mechanical ventilation, length of ICU stay, and length of hospital stay were analyzed. Result: The median age of the patients was 61 years with a male preponderance. Hypertension is the most common co-morbidity associated with diabetes patients. The median blood sugar level was consistently high in the non-survivors although the result was not statistically significant. Clinical management showed that 84% of patients received insulin, 16% (oral hypoglycemic agents) 72% (steroids) and (64%) mechanical ventilation. The median ICU stay was 8(2-72) days, the median hospital stay was 13(6-79) days and overall mortality in patients with diabetes with COVID-19 was 52%. Conclusion: Hyperglycemia in critically ill COVID-19 patients with preexisting diabetes shows worst outcome in terms of complications, need for mechanical ventilation, and mortality a well-designed prospective study is needed to determine the optimal target for glucose control and its effect on outcomes in patients with diabetes and COVID-19.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48843004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized, Double-Blind, Monocentric, and Placebo-Controlled Blood Glycemic Response Evaluation of Sweetch, a Natural Sugar Replacement Blend, on Healthy Volunteers","authors":"Minh Le A, Tu Do A, A. Khaiat","doi":"10.23937/2377-3634/1410165","DOIUrl":"https://doi.org/10.23937/2377-3634/1410165","url":null,"abstract":"Diabetes mellitus is a serious global concern due to its long-term health-related effects and the financial burden it poses to healthcare systems and families around the world. Excess consumption of sugar is one of the main causes of the issue. There are many sweetening ingredients that claim to be the solution to substitute normal sugar while maintaining the blood sugar level at a low level, yet the evidence is lacking and not always substantiated. Sweetch Natural Sugar Replacement is a proprietary natural sugar alternative product composed of a blend of different plant-derived sweetening ingredients. It has zero calories, no added flavor, non-GMO, and the same taste profile and measure as sugar (1:1 replacement). It is appropriate in drinks as well as any form of cooking. The objective of this study is to evaluate changes in blood sugar levels, as well as the safety of human volunteers after oral absorption of Sweetch Natural Sugar Replacement, substantiating Sweetch claim on zero glycemic response. The efficacy and safety analyses were performed using the principles of a fasting blood sugar level test on 22 randomized subjects practicing a healthy lifestyle. Participants were divided into 2 groups: An active group using the investigational product (IP; 50 g of the IP dissolved into mineral water.) versus a controlled group using a placebo (plain mineral water). After 12 hours of overnight fasting, volunteers took their drink orally and their blood samples were taken at specific time points (T0, T30 min, and T2 h) to measure blood glucose levels. Results indicate that there is no significant difference in the average blood glucose level at various time points between the active group and the placebo group. This study confirms that Sweetch Natural Sugar Replacement does not cause any noticeable changes in blood sugar levels post-oral administration. No adverse health events were observed throughout the study. Through this study, Sweetch Natural Sugar Replacement’s claim on zero glycemic index (GI) is proven legitimate.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48493990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of Continuous Glucose Monitors in a Group Medical Visit Setting","authors":"Kirk Julienne K","doi":"10.23937/2377-3634/1410164","DOIUrl":"https://doi.org/10.23937/2377-3634/1410164","url":null,"abstract":"Aim: The aim of this study is to assess the utilization of CGMs in a GMV setting to improve patient activation and engagement, quality of life, and metabolic outcomes including glycemic control through modified lifestyle behaviors in patients with Type 2 diabetes. Background: Group medical visits (GMV) are an evidence-based care model shown to improve outcomes in diabetes. Monitoring tools that readily demonstrate cause-and-effect relationships between recommended lifestyle interventions and optimal glycemic control in the short and long term can be utilized to improve diabetes outcomes. Continuous glucose monitoring systems (CGMs) are wearable devices that continuously measure interstitial glucose and provide valuable feedback on glycemic changes in response to diet and exercise. With this data, patients are given nearly immediate feedback, empowering them to make dynamic behavioral changes. Methods: We implemented GMV for 16 adults from an academic community-based primary care clinic. Two separate cohorts consisting of 8 participants each, met for a total of 14 weeks with sessions every 2 weeks. Baseline HbA1c and lipid panels were collected within 3 months of the first GMV and at the end of the 14 weeks. Validated questionnaires (PAM-13 and SF-12) were collected at the initial and final GMV. Paired t-tests for these differences between the two times were also calculated. Significance was set at p < 0.05. Findings: At the end of the 14 weeks, participants had a significant reduction in HbA1c (0.4%; p < 0.05), weight (6.4 lbs; p < 0.05), and average glucose (calculated by CGM, 21.1 mg/dl; p < 0.05). 38.5% of participants decreased their HbA1c to the prediabetes range. There was no significant difference for lipids, PAM-13, or SF-12 or blood pressure. Participants reported subjectively that the CGM was helpful to see the relationship of foods and their glycemia.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48890431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes and Driving - Significant Deficits in Knowledge and Practice","authors":"Khan In, Capatana F, Premawardhana Ld, Adlan Ma","doi":"10.23937/2377-3634/1410163","DOIUrl":"https://doi.org/10.23937/2377-3634/1410163","url":null,"abstract":"Motor vehicle drivers who are diabetic and health care professionals who care for them, lack awareness of regulations pertaining to safe driving. We aim to assess their knowledge, practice, and adherence to recommendations in this study of diabetics who drive while taking hypoglycaemic agents. Methods: We recruited 185 subjects from our secondary care diabetes clinic, and obtained details about demographic characteristics, medications, blood glucose monitoring, hypoglycaemia and knowledge of current regulations. Results: The majority were males (72.5%) and their median age was 60 years. 92.4% of subjects were on hypoglycaemic agents (109 on insulin and 62 on sulphonylureas alone or in combination). Of the subjects on hypoglycaemic agents - (a) 87% regularly monitored blood glucose - 60% of them did so twice/day or more; (b) 66.5% had been advised by health care professionals about driving regulations (77% of those on insulin); (c) 79% thought their knowledge was adequate about regulations and 21% requested more information (d) 55.4% reported hypoglycaemic awareness and (e) only 55.2% checked blood glucose before driving. Discussion: This study confirms deficits in knowledge and practice amongst both patients and healthcare professionals about diabetes and driving. Educating these groups appropriately should become a priority locally and nationally.","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47051080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic Complications and Associated Factors among Diabetic Patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia","authors":"Gedamu Melak, Mulusew Camilla, Senbeta Mamo Feyissa","doi":"10.23937/2377-3634/1410160","DOIUrl":"https://doi.org/10.23937/2377-3634/1410160","url":null,"abstract":"Background: Diabetes mellitus is a rapidly increasing chronic disease associated with complications resulting in long-term damage and failure of various organ systems. In Ethiopia, there is a dearth of evidence on the prevalence of Diabetic complications. Objective: To assess the prevalence of diabetic complications and associated factors among diabetic patients on follow-up at the diabetic center of","PeriodicalId":92797,"journal":{"name":"International journal of diabetes and clinical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47540106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}