{"title":"Metastatic Colorectal Cancer in two Young Patients with Inflammatory Bowel Disease – Relevance of Tight Endoscopic Surveillance Especially in Early-Onset IBD and Review of the Literature","authors":"H. E, Nagl S, F. C., E. A, Messmann H, Schnoy E","doi":"10.47829/coo.2021.5501","DOIUrl":"https://doi.org/10.47829/coo.2021.5501","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90855314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 and Cancer","authors":"Hunis Ap","doi":"10.47829/COO.2021.4403","DOIUrl":"https://doi.org/10.47829/COO.2021.4403","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88065407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Guo, H. Wang, Y. Ma, B. Han, G. Liu, Z. Yang, Z. Liang, F. Hu, Xiucai Ding
{"title":"Dosimetric Consequences of Intrafraction Variation of Tumor Motion in Lung Stereotactic Body Radiotherapy","authors":"Y. Guo, H. Wang, Y. Ma, B. Han, G. Liu, Z. Yang, Z. Liang, F. Hu, Xiucai Ding","doi":"10.47829/COO.2021.4102","DOIUrl":"https://doi.org/10.47829/COO.2021.4102","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89196204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screening Tests for Cervical Cancer Up-To-Date","authors":"Hernandez Vmv","doi":"10.47829/coo.2021.5401","DOIUrl":"https://doi.org/10.47829/coo.2021.5401","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87136743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contextual Factors Associated with Health-Related Quality of Life in Older Adult Cancer Survivors","authors":"S. Vang","doi":"10.47829/coo.2021.5603","DOIUrl":"https://doi.org/10.47829/coo.2021.5603","url":null,"abstract":"1. Abstract 1.1. Aims: The purpose of this study was to examine contextual factors associated with physical and mental health-related quality of life (HRQOL) in older adult cancer survivors. 1.2. Methods: This study is a secondary data analysis of the 2014 Behavioral Risk Factor Surveillance System. Only adults age 65 and older who had a cancer history in the Cancer Survivorship module were included (n=3,846). 1.3. Results: Racialethnic minorities were 52% less likely to report good mental HRQOL compared to non-Hispanic whites. Having completed treatment also improved odds of having good mental HRQOL. Being employed and having exercised in the past month increased likelihood of having good physical HRQOL. Having physical comorbidities and a history of depression were related to poor mental HRQOL. 1.4. Conclusion: Older adult cancer survivors who are unmarried, experienced cost as a barrier to care, have physical comorbidities, or a history of depression should be included in interventions to improve HRQOL. Special attention should be paid to older adult cancer survivors who have had a stroke, as they could be at greater risk of poor physical and mental HRQOL. To reduce disparities in HRQOL of cancer survivors, greater effort needs to be made to improve the HRQOL of racial/ethnic minorities and those facing difficulties completing treatment. Greater research is needed to understand the effect of race, aging, and cancer on HRQOL 2. Introduction Adults diagnosed with cancer are living longer now than ever before. Today, 69% of cancer patients in the United States (U.S.) can expect to survive 5 years or more beyond diagnosis, up 20% from the previous three decades [1]. Of these cancer survivors, 62% are older adults (age 65 years or older); by 2040, this proportion is expected to climb to 73%, resulting in over 19 million older adult cancer survivors [2]. Recognizing these trends, professional organizations and governmental agencies, such as the American Society of Clinical Oncology and the National Institutes of Health have developed best practices for providing clinical care to older adult cancer survivors with the aim of promoting health-related quality of life (HRQOL). HRQOL is a subjective assessment of the impact of a disease on an individual’s quality of life, particularly the extent to which the disease interferes with one’s physical and mental functioning [3]. It is also a meaningful metric for assessing a cancer patient’s well-being in comparison to the non-cancer population [4, 5]. Furthermore, HRQOL has strong prognostic value, as HRQOL declines are linked to poorer survival following diagnosis. As greater survival is achieved from cancer, HRQOL is increasingly being recognized as an important endpoint in clinical cancer care. It is widely acknowledged that older adult cancer survivors experience worse HRQOL following a cancer diagnosis. Cancer and its sequelae can cause chronic pain, fatigue, and other decrements in physical functioning ","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85808685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Molecular Biomarker Prediction Model for Preoperative Radio sensitivity in Rectal Cancer: An Analysis of 33 Patients’ Information","authors":"Wang Y, Ai Y, L. R, W. F, Zhang J, Dai Y, J. W","doi":"10.47829/coo.2021.5402","DOIUrl":"https://doi.org/10.47829/coo.2021.5402","url":null,"abstract":"Wang Y1, Ai Y2, Li R1*, Wang F1, Zhang J1, Dai Y1 and Jian W1 1Department of radiation oncology, The First Affiliated Hospital of Kunming Medical University, Kunming, China 2Department of radiation oncology, The Third Affiliated Hospital of Kunming Medical University, Kunming, China A Molecular Biomarker Prediction Model for Preoperative Radiosensitivity in Rectal Cancer: An Analysis of 33 Patients’ Information","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86267593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Progress in Chronic Lymphocytic Leukemia","authors":"I. Ali, Y Jiamg, W. Fan, S. Liu","doi":"10.47829/coo.2021.5101","DOIUrl":"https://doi.org/10.47829/coo.2021.5101","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84125501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extensive Marjolin’s Ulcer of Scalp in a Patient with Cardiac Dysfunction - A Reconstructive Challenge","authors":"Rout Sk, Giri Sk, R. Panda, S. Bansal, N. Singh","doi":"10.47829/coo.2021.4502","DOIUrl":"https://doi.org/10.47829/coo.2021.4502","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78295611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast MR Imaging Helps Differentiate Malignant and Benign Mammographic Microcalcifications: A Study Based on the 5th Edition of BI-RADS","authors":"L. R., W. L., W. D., Z. Y., Chen Y","doi":"10.47829/coo.2021.5301","DOIUrl":"https://doi.org/10.47829/coo.2021.5301","url":null,"abstract":"Objective: To investigate whether breast MR imaging could help in differentiating malignant from benign mammographic microcalcifications. Methods: The study consecutively included 106 patients with 112 mammographic microcalcifications between January 2014 and April 2017 in our institute. Pre-operative mammograms and breast MR images were analyzed in a blind manner by two trained breast imaging subspecialists. Each lesion was described and categorized according to the 5th BI-RADS atlas. AUC, sensitivity, specificity, positive Likelihood Ratio (LR) were used to evaluate the value of MR imaging in differentiating malignancy from benignity. Results: Of the 112 lesions, pathologic results revealed 81 benign, 12 pre-cancerous and 19 malignant (10 invasive cancer and 9 ductal carcinoma in situ) findings. The number of lesions assigned to BIRADS 3, 4B, 4C, and 5 was 2, 92, 16, and 2, respectively, resulting in a PPV of 14.7% (17/108) for MG-BI-RADS 4 microcalcifications. The number of MRI classification 1 to 5 to the corresponding BI-RADS 4B microcalcifications were 37, 2, 33, 27, and 9 respectively. MR-BI-RADS criteria ruled out 72 benign MG-BI-RADS 4 lesions with none malignancy missed, while MRI enhancement criteria ruled out 46 benign lesions. MR-BI-RADS criteria were significantly better in AUC (0.896, P<0.0001), specificity (79.12%, P<0.0001), and positive LR (4.79) than mammography and MRI enhancement criteria. Conclusion: Breast MR imaging is useful in the evaluation of BI-RADS 4 mammographic microcalcifications by avoiding 79.12% unnecessary biopsies with none false-negative diagnosis.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81650054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monge Blandon A, Ballestero Masis M, Peralta Jm, Oliver Rex M, Ruiz Monteagut N, S. L, Ruiz Baixauli J, R. I, Recio J, Pedro Rollan
{"title":"Bone Marrow Aplasia Secondary to Etoposide (Vepesid) in A Patient Who Simulated a Lung Tumor, Finally Being Diagnosed with Munchausen Syndrome. A Reflection of The Telephone Consultations in The COVID 2019 Pandemic","authors":"Monge Blandon A, Ballestero Masis M, Peralta Jm, Oliver Rex M, Ruiz Monteagut N, S. L, Ruiz Baixauli J, R. I, Recio J, Pedro Rollan","doi":"10.47829/coo.2021.5602","DOIUrl":"https://doi.org/10.47829/coo.2021.5602","url":null,"abstract":"Bone Marrow Aplasia Secondary to Etoposide (Vepesid) in A Patient Who Simulated a Lung Tumor, Finally Being Diagnosed with Munchausen Syndrome. A Reflection of The Telephone Consultations in The COVID 2019 Pandemic Monge Blandon A1*, Ballestero Masis M1, Peral Blanco JM1 Oliver Rex M2, Ruiz Monteagut N2, Suarez L3, Ruiz Baixauli J4, Romaniouk I4, Recio J4 and Pedro Rollan5 1San Judas Tadeo University. Costa Rica 2Catholic University of Valencia, Spain 3Oncomedicine department, Hospital Vithas 9 of October, Spain 4Intern Medicine, Hospital Vithas 9 of October, Valencia, Spain 5Cardiology, Hospital Vithas 9 of October, Valencia Spain","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85856071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}